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testing the paradigm of a single plastid origin in eukaryotes
photosynthesis was acquired by eukaryotes through endosymbiosis with cyanobacteria which resulted in new cellular organelles the plastids from the origin of plastids evolved the first eukaryotic algae giving rise to land plants but also triggering the evolution of most photosynthetic eukaryotes by subsequent endosymbio...
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stable isotope study of bone and dental remains hydrogen and oxygen methodological developments
the study of the interactions between ancient societies and their environment is a key element to decisionmaking in the global context of climate change stable isotope analysis of biological bone and dental remains provides insights into climatic conditions dietary habits and geographical mobility of modern and past po...
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ocean night helping society understand the importance of the marine ecosystem
life started in the oceans oceans cover the majority of earths surface and are the single largest ecosystem on the planet billions of humans live in coastal areas and depend on the functioning of this ecosystem to live unfortunately human activities are seriously endangering the health of the marine ecosystem it is the...
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space4earth
globeeye provides a new unique and complete perspective on global economic environmental and social developmentsleveraging frontier technologies in space data and artificial intelligence it delivers valuable insights for decisionmakers in financebusiness and government it contributes to overcoming out times major chall...
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the best way to know your health we have integrated a medical device into a toilet allowing people to take an autonomous exam related to several health parameters with simplicity and regularity
abluteis the best way to know your health by integrating a urinalysis device into a waterefficient toilet people can take exams with the simplicity of using a bathroom regular screening is the most reliable method to early detect diseases ablute delivers simplicity to health examination fostering regularity the equipme...
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ancient viruslike transposons from horizontal gene transfer to the evolution of novelty
from antiparasitic toxins in butterflies to antifreeze proteins in fish horizontal gene transfer hgtthe nonsexual exchange of genes between specieshas been observed in all major eukaryotic lineages however one of its most fascinating aspects the transfer mechanism remains a mystery despite decades of research how can d...
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synthetic antibody synab receptors for the detection and isolation of cyclic depsipeptide cdp toxins in food samples
food safety plays a critical role in society when it comes to avoiding food poisoning most of the attention goes to preventing microbial growth in food products however the cause of intoxication is the presence of toxins produced by these microorganisms yet standard industrial or household food processing and preparati...
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a step change in prediction mapping acceptance testing and costeffective mitigation for railway noise and vibration
quieterrail aims to introduce a step change in predicting and mapping railway noise and vibration in the acceptance testing of rolling stock and in promoting costeffective noise mitigation the established twinsbased approach for rolling noise is extended to include curves squeal noise models are developed including fla...
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improving green innovation for the blue revolution new tools and opportunities for a more sustainable animal farming
animal health and welfare are issues of high research priority for european aquaculture in particular improving animal welfare whilst reducing the use of veterinary drugs are current research priorities in line with minimizing the environmental impact of the industry preventing or reducing the impact of disease is of p...
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when was greenland green perspectives from basal ice and sediments from ice cores
green2ice will investigate the deepest and oldest ice and basal sediments drilled from the greenland ice sheet gris ice cores have been drilled the last 55 years but the deepest ice containing basal materials has been preserved until now and still holds undeciphered paleoclimatic messages the breakthrough of green2ice ...
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zeroco2 cement through carbonation of calcium silicates and aluminates
contrabass zeroco2 cement through carbonation of calcium silicates and aluminateswe live in a world of concrete according to the global cement and concrete association gcca cement is consumed at a rate of 150 tonnes each second and it accounts for approximately 8 of all co2 emissions and 7 of industry energy use in ord...
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computational scanning for responding clonotypes in immune repertoires
personalized medicine promises to exploit the diversity of human immune repertoires to design targeted t cell and b cellbased vaccines and therapeutics however even for mass vaccine design identifying responding clonotypes to new viruses is costly labor intensive and time consumingrespond turns existing algorithmic sol...
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protein landscapes the political geography of the production and consumption of animal proteins
despite the devastating effects of the meatdairy industry on climate and environment the production and consumption of animalbased protein is at historically high levels i refer to this as the protein paradox why are we collectively unable to reduce our reliance on meat and dairy from the extant literature we know that...
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the chromite record of mafic crustal growth
understanding earths crustal growth is crucial to understanding the evolution of its tectonics the birth of the first continents and the fundamental changes that transformed earth into a habitable planet however much of our understanding of earths crustal growth is predicated on a single mineral zircon that is strongly...
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identifications a psychoanalyticpolitical study of performances countering intraeuropean cultural racism
the enlargement of the european union to include central and eastern europe 2004 2007 brought with it the rise of rightwing politics in western europe factors that contributed to the ensuing institutionalisation of rightwing parties include the european debt crisis 20092018 the imposing of austerity measures and the un...
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strengthening the resilience of textile aerospace and construction smes to transition towards greener and more digital sectors with social and business innovation
in transit aims to strengthen the resilience of textile aerospace and construction smes towards greener and more digital sectors withsocial and business model with a mixed support mechanism including individual assessment support and a lump sum and coachingto ensure their consolidation and sustainabilityin transit will...
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towards reliable and safe gfr
gascooled fast reactor gfr is considered as one of the six most promising advanced nuclear reactor technologies supported worldwide by the generation iv international forum and esnii in europe with concepts under development in europe and the usa it excels in versatility combining very high core outlet temperatures and...
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complex contagion of childcare strategies amongst lowincome parents
background high quality childcare greatly improves outcomes in later life yet childcare access and usage are distributed unevenly leading to amplified inequalities in later life outcomes parents from lowincome households are 50 less likely to use formal childcare services than highincome households and use them when th...
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the genetic basis of host resistance and pathogen virulence in the septoriawheat pathosystem
increasing agricultural sustainability has become more than ever a priority in this sense wheat plays a central role in eu agriculture as a major crop and controlling yield losses due to diseases can be a serious bottleneck for agricultural sustainability septoria tritici blotch stb caused by zymoseptoria tritici is a ...
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using museum specimens to understand mushroom population genomics
museum collections and other repositories contain a vast amount of specimens associated with metadata detailing the locationhabitat and ecological observations of the specimen at the moment of collection since these specimens are biological tissues dnasequencing techniques can be used to study them however their applic...
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a principled plan to prevent transient execution attacks
ghostbuster is a research program to stop advanced transient execution attacks which by themselves already rank among the most advanced attacks everby finding vulnerable code fragments analyzing them for exploitability and injecting mitigations where needed the vulnerabilities such as spectre meltdown and others origin...
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democratising and making sense out of heterogeneous scholarly content
scilakes mission is to build upon the openaire ecosystem and eosc services to a facilitate and empower the creation interlinking and maintenance of scientificscholarly knowledge graphs skgs and the execution of data science and graph mining queries on top of them b contribute to the democratization of scholarly content...
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bioeconomy and circular economy fair network digitally fair and accessible network for reducing ghg activities with circular and bioeconomy models
bioeconomy and circular economy fair network biofairnet is designed to support hotspots and specific value chains heavily reliant on greenhouse gas ghgintensive industries into leaders of a sustainable biocircular economy via a digital cooperative network the network understood as a digital platform and stakeholder eng...
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supramolecular photocatalytic latestage ch functionalization
organic synthesis is still one of the main limiting factors in drugdiscovery projects traditionally the generation of compounds libraries requires tedious synthetic routes to introduce modifications into the lead compound thus the implementation of new methodologies to modify drugs in a selective way in the late stages...
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patronage and european perspective in brandenburg prussia the painter etcher johann friedrich wentzel 16701729
eubrand sheds light on a forgotten chapter of europes intellectual and artistic history based on the following research question how did painting contribute to the creation of a visual language of absolutism during the reign of the first prussian king frederick i eubrand fosters research and innovation by combining his...
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compressed sensing for climate a novel approach to localize quantify and characterize urban greenhouse gas emitters
climate change is a defining issue of our time without significant rapid greenhouse gas ghg emission reductions we will face unpredictable consequences for climate and life to effectively reduce ghgs the emissions must be accurately quantified and unknown emitters found however measuring global ghg emissions is very ch...
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dso for digital twins
dsos for digital twins accelerating the uptake of digital twins of the european electricity grid across europe
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science platform cloud infrastructure for outsize usage scenarios
the spacious project aims to boost the scientific exploitation of esa mission data by offering a new computational framework for astrophysical research that requires big data and data mining technologies to be employed spacious will raise the competitiveness of the eu scientific community by increasing the big data and...
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design study for a european infrastructure on advanced genomics technologies
innovation in the genomics field is extremely intense and requires high upfront investments the toolbox of sequencing platforms with unique features that require specialized training and leverage extensive crossfunctional expertise is rapidly expanding the easigends project evolves from two eu infrastructure projects t...
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young international academics postdoctoral programme
the young international academics postdoctoral programme yia is a career development program proposed by the university of luxembourg unilu to nurture earlycareer postdoctoral applicants to gain momentum in interdisciplinaryintersectoral research yia applicants are international talents willing to propose and realize t...
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social and human centered xr
the social and human centered xr sun project aims at investigating and developing extended reality xr solutions that integrate the physical and the virtual world in a convincing way from a human and social perspective the virtual world will be a means to augment the physical world with new opportunities for social and ...
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making old objects valuable again the cultural economic challenges and sustainability opportunities of antiques in the 21st century
what do old porcelain wooden furniture and silverware have in common all of these antiques fall into the category of informal heritage regardless of their cultural significance many of these objects remain on the margins both in cultural institutions and scholarly research as a result the question of how antiques are s...
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overnight vulnerable emotion reset normalizing invalidating generalized hyperaroused tension
anxiety and insomnia account for onethird of the global mental health burden prognosis is poor chronicity and relapse are common because treatment effectiveness is moderate while this situation calls for treatment innovation the required knowledge on targetable key mechanisms is lackingtheir shared core symptom is hype...
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green innovations in hydrogen for sustainable energy transition
the h2start project aims to establish a centre of excellence coe in stara zagora to spearhead the advancement of innovative technologies for renewable hydrogen production and uptake as an essential component of the transition towards a lowcarbon and energysecure economy renewable hydrogen holds tremendous promise for b...
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fair food and trade systems for africa through food convergence innovation
the fci4africa project champions a holistic approach to african agriculture promoting fair sustainable climateneutral and healthpromoting trading practices while ensuring economic prosperity at all levels and respecting human rights it bridges the gap between technical compliance and social justice by empowering smallh...
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the politics of wildfires a comparative study of norms power and conflict in the global south
extreme wildfires have been on the rise across the globe due to climate change and other human actions despite the abundant literature on fire ecology and a recognition of the linkages of wildfires to global warming a patchy understanding of the relationship between fire and anthropogenic actions and their political dr...
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derisking the drug discovery process of oncology and metabolic diseases
excellence vitala technologies brings together organonchip ooc hyperpolarized magnetic resonance spectroscopic imaging hp mrsi and advanced data analysis tools to provide a patented and revolutionary test for the monitoring of the efficacy in treatment of a new drug moving through the metabolic pathways of a cell this ...
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accelerated additive manufacturing digital discovery of a new process generation
additive manufacturing am by laser powder bed fusion lpbf has the potential to revolutionize future product development design and supply chains since the underlying multiscale physics are not well understood its potential can presently not be exploited suboptimal process conditions lead to severe defects on different ...
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philosophy of social physics
philosophy of social physics sophy intends to explore the impact of physics on the genesis of the social sciences and to define the current use of social physics in the scientific discourse on big data related to crowd behaviors the general hypothesis is that physical narratives and notions such as force resistance bal...
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joint sensing and communications for future interactive immersive and intelligent connectivity beyond communications
the instinct project is going to enable globally sustainable interactive immersive and intelligent beyond communications 6g connectivity by developing three complementary but critical breakthrough technology pillarssensingassisted communication technologies thus allowing localization tracking mapping monitoring imaging...
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boosting ingenium for excellence
the bi4e project is born out from the ingenium alliance of european universities with the ambition of enhancing the existing interuniversity cooperation between the partner universities as well as with other entities both international and local and to strengthen the higher education institutions heis capacity to meet ...
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miniaturized plasma emission spectroscopybased breath analysis for unobtrusive athome monitoring and prediction of copd exacerbations
patients suffering from chronic obstructive pulmonary disease copd suffer from persistent airway obstruction causing shortness of breath and extreme fatigue patients are repeatedly hospitalized due to acute flareups known as exacerbations which are largely responsible for the morbidity and mortality associated with cop...
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beyond influence the connected histories of ethiopic and syriac christianity
the innovative beinf project interrogates the connected histories of ethiopic and syriac christianity in their various complexities and nuances it accomplishes this task through a series of five discrete but complementary case studies addressing 1 aramaic loanwords in ethiopic 2 the socalled nagran episode in which the...
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resilient multimodal freight transport network
remunet identifies and signals disruptive events and assesses their impact on multimodal transport corridors it reacts quickly and seamlessly upon disruptive events in realtime it supports tmsproviders to improve route planning resilience remunet communicates alternative predefined multimodal transport routes to logist...
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autonomous learning agents in physics
in recent years the use of machine learning ml for the study of physics has experienced a strong boost however most of the machines used are black boxes and the causal relation between inputs and outputs is often impossible to extract nonetheless a critical aspect when dealing with physical systems is not only to make ...
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global estimates for nonlinear stochastic pdes
the project is concerned with the global behaviour of solutions to stochastic partial differential equations spdes from mathematical physics which arise eg in the description of scaling limits of interacting particle systems and in the analysis of quantum field theories the equations contain noise terms which describe ...
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participatory algorithmic justice a multisited ethnography to advance algorithmic justice through participatory design
ai comes with great promises but more critically it comes with demonstrated harms from racial and gender bias to discrimination wrongful arrests defamation surveillance or the extractive labor and practices required for its creation i contend that the most concerning aspect of ai is the exacerbation of existing structu...
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giving voice to hispanic chant through a phylogenetic study of medieval plainchant
plainchant the sacred christian chant is the most ancient western corpus preserved in musical notation before the unifying adoption of the gregorian liturgy throughout europe in the 9th century a number of liturgical families each one with its own chant repertoire emerged in the ancient western roman provinces among th...
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liberation analysis for optimizing extraction and processing of crms
the crm act together with other eu policies towards the green and digital objetives of the ce and the eu current context pose some challenges and needs to the extractive and processing industries improve and facilitate access to raw materials and reduce eu dependency increase circularity ensure recycling into secondary...
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universal prevention of maternal perinatal mental disorders and its implementation as normalized routine practice
maternal mental disorders are the most common complications during pregnancy and within the first year after childbirth defined as the perinatal period and are the leading cause of maternal suicide affected mothers cannot function properly causing a devastating impact on the entire family effective primary prevention i...
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rylenediimidebistriazinyls synthesis characterization and magnetic properties
polycyclic aromatic hydrocarbons pahs with stable openshell groundstates are needed for stateoftheart applications eg organic spintronics electronics energy storage etc herein we propose rylenediimides naphthalenediimide ndi perylenediimide pdi as promising pah scaffolds for building multifaceted blattertype diradical ...
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the role of lasp1 and pdlim4 in stress fiber dynamics and mechanoresponsive signaling
the lim domain proteins lasp1 and pdlim4 are associated with the actin cytoskeleton and implicated in many diseases however their precise molecular functions are poorly understood recent protein interaction studies from my host laboratory provided evidence that these two proteins associate with stress fibers sfs the co...
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gut microbiotainduced tregs for inflammatoryboweldisease ibd immunotherapy miti2
our project focuses on the regulatory properties of a subset of microbiotaspecific tr1like regulatory t treg cells for which we have already shown an unprecedented association with the clinical outcome of patients in various inflammatory diseases for a therapeutic use in inflammatory bowel diseases ibd ibd is a disabli...
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medieval appetites food plants in multicultural iberia 5001100 ce
the islamic conquest of iberia in the 8th century brought in profound changes in the political social and economic realms that transformed the everyday life of local rural and urban communities technological innovations and the arrival of new crops impacted their agriculture diet and culinary practicesplants were prese...
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control of hydrogen and enrichedhydrogen reacting flows with water injection and intensive strain for ultralow emissions
we are racing against time to find a clean yet abundant energy source able to arrest global warming hydrogen has all the characteristics to address this challenge it can be produced cleanly from water it is incredibly energetic and more importantly it is carbonfree however hydrogens strong reactivity and diffusivity ma...
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minimisation of the offshore wind and tidal turbine acoustic footprint on marine life
for renewable energies to be sustainable in the future their impact and harmful effects on the environment should be minimum recent evidences suggest that offshore wind and tidal turbines can have an acoustic damaging impact on marine life due to the sustained generation of noise which propagates very efficiently under...
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on rosalyn turecks legacy for bach performance in the 21st century
js bachs musical legacy is astonishingly rich we have been responding to his music for more than 300 years the american keyboardist rosalyn tureck 19132003 devoted more than six decades to performing researching teaching and writing about bachs works as well as music and arts in general she has left an abundant heritag...
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taxonomy and azole resistance in aspergillus section flavi
the project on taxonomy and azole resistance in aspergillus section flavi aims to investigate the classification and drug resistance patterns of fungal species within this specific section aspergillus section flavi comprises various species known to produce carcinogenic aflatoxins posing significant risks to human and ...
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induction of neuromuscular plasticity for natural motor rehabilitation
neurorehabilitation technologies aim to promote functional neural plasticity in patients suffering from neuromuscular disabilities noninvasive systems for the magnetic or electrical stimulation of the neural pathways are particularly promising for interfacing directly with the nervous system of the patients and restori...
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the early exploitation of cetacean in western europe during the late upper palaeolithic
the whalebone project builds upon new advances in the study of past human adaptations to coastal environments focusing on a key case study early interactions between late upper palaeolithic foragers and cetaceans at the end of the last glaciation in western europe over the last decade a growing body of evidence suggest...
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should we prohibit luxury emissions of greenhouse gases on top of price constraints
many share the intuition that the luxury emissions of the global top 1 are morally wrong given the current state of the climate crisis yet the subsistenceluxury distinction has been used so far to justify a right to subsistence emissions rather than a ban on luxury and extravagant emissions prohiblux aims to develop a ...
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selflearning aibased transport optimization software as a service for the most complex logistics scenarios in realtime enabling doubledigit cost co2 and tyre wear savings
smartlanes aibased dispatch software logisticsbrain is a selflearning cloudbased software for automated transport optimization smartlanes core technology the scenariobased optimization ai algorithms in combination with kpi and process analysis optimizes costs by 40 planning time by 90 resources co2 emissions and fine d...
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worlds first devicebased treatment for small abdominal aortic aneurysms based on revolutionary new treatment paradigm
the angiolutions device is a firstofitskind device stopping the lifethreatening progression of small abdominal aortic aneurysm aaa a pathological dilation of the aortaangiolutions awardwinning patentprotected solution leverages a fundamentally new understanding of aaa growth discovered by the founders at stanford unive...
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european identity theft observatory system
eithos will develop a novel identity theft observatory system empowering european citizens law enforcements agencies leas and policy makers to further contribute to the prevention detection and investigation of identity theft related crime it will provide a common gateway for identity theft information and intelligence...
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in silico bioevolutio novel ai paradigm for molecular biology
the success of phage therapies relies on correctly matching a therapeutic phage to bacterial strain however calibration of therapy recipe may last for years presented solution enable to accelerate this by in silico simulations on ai platform for in vitro it is able to find optimal phage that meets the phenotype imposed...
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membrane electrode assembly for the high pressure electrochemical conversion of co2 to c2h4
the electrochemical conversion of co2 to chemical fuels is a promising technology for recycling co2 and closing the carbon cycle amon the different products of the electrochemical reduction of co2 multicarbon c2 product are more desirable because of their high energy density and high market price among them ethylene is...
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celtic language and identity in northern italy and the alpine region
the research project cliniar celtic language and identity in northern italy and the alpine region investigates the linguistic and sociolinguistic landscape of celtic northern italy and the alpine region in the iron age the project will be conducted at maynooth university mu ireland under the supervision of the leading ...
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faithbased refugee relief in europe connecting the empirical and the ethical
fabric develops a new ethics of migration by understanding and utilizing the moral insights and the moral ideas that faithbased refugee relief organizations develop and deploy in practice for the crossdisciplinary debate about the ethics of forced migration in europe globally forced migration is one of the most pressin...
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the epistemology of dark matter and modified gravity
andromeda is an unprecedented study regarding the philosophy and epistemology of dark matter and modified gravity the project will synthesize existing knowledge from cosmology and philosophy of science in order to realize an innovative and original study of the epistemological foundations of the debate between theories...
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structural and biophysical characterisation of insulin receptor and glutamate receptors ampar and nmdar in complex with sorcs coreceptors 1 and 2
type ii diabetes t2d alzheimers disease ad and parkinsons disease pd are common agerelated diseases which have reached endemic levels and become a burden for the global health lifestyle and environment are risk factors but cannot explain all cases genes also predispose for these diseases common for t2d ad and pd is abn...
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dynamic resource scheduling in massive mimo based noma with rf imperfections and energy harvesting for 6g networks
yahya6g aims to propose new signal processing solutions doped with machinelearning we will focus on the detectionand compensation of rf imperfections in mmimo massive multiple input multiple output based noma nonorthogonal multipleaccess pair in other hand yahya6g target is to minimize the longterm power consumption ba...
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boosting excellence in environmental epigenetics
the epiboost project joins a widening partner and two internationallyleading partners that will steer a solid capacitation strategy towards tackling the challenges to the recently proposed uptake of epigenomics by environmental assessment frameworks capacitation activities cover for 5 specific objectives the 1st is to ...
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high throughtput electrophysiological measurements coupled with transcriptomics to reveal cellular dysfunction in type 2 diabetes
in this project i will develop methods to simultaneously measure transcriptomes with singlecell resolution and perform highthroughput functional measurements of individual pancreatic islet cells i will focus on and cells which regulate glucose levels by secreting the two main glucoregulatory hormones insulin and glucag...
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citiobs enhancing citizen observatories for healthy sustainable resilient and inclusive cities
citiobs will consolidate and apply tools and practicebased knowledge for cocreating data knowledge and local action via citizen observatories cos these tools will enhance existing and new citizen observatories to engage citizens and marginalised communities add value to environmental observations in the urban context i...
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reprogramming endothelial cells in immunecold tumors
lung cancer is the leading cause of cancerrelated deaths worldwide currently immunotherapy it is the standard of care for the treatment of some subtypes with only nominal success it works best in inflamed hot tumors and is often ineffective in immune celldesert cold tumors in krasmutated lung adenocarcinoma luad the mo...
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biocatalytic fluorescence switchon polymerizations for signal amplification in ultrasensitive diagnostics and biosensing of malaria
malaria is one of the most catastrophic infectious diseases causing nearly 250 million deaths in 2021 according to who although malaria is curable delayed diagnosis is the leading cause of death in malaria patients the major obstacle in malaria diagnosis is clinical assessment by conventional methods which requires wel...
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measuring and modelling tectonic co2 emissions through time
geological processes governed paleoatmospheric co2 variations and exerted major control on past climate change beyond the millionyear time scale vast deep carbon reservoirs are known to be activated at continental rifts where the faulted lithosphere provides co2 pathways and where recent surveys detected massive co2 em...
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promoting ocean and water literacy in school communities
probleu will expand and support the network of european blue schools attract a wide diversity of new members improve ocean and water literacy across school communities and contribute to the objectives of the mission in particular 1 to protect marine and freshwater ecosystems and biodiversity and 2 to prevent and elimin...
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croatiacyprus excellence hub on ecoinnovative technologies for healthy and productive seas
the main goal of the seatechub project is to strengthen croatian and cyprus placebased innovation ecosystems and improve access to excellence for ri actors by crossborder collaboration on a common strategy and alongside value adding chains within the area of ecoinnovative technologies for healthy and productive seas fo...
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predicting the fate of plastic on beaches by their 3ddistribution and weathering processes
recent global plastic pollution models predict that two thirds of the plastic mass released from land into the ocean since 1950s is likely to have stranded around the worlds shoreline yet our knowledge about the degradation burial and transportation fate of beached marine plastic debris mpd remains limited and little i...
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fintech investor network and ecosystem
fine aims to create more inclusive and connected networks between fintech ecosystems on a local and international level by promoting collaboration between investors through coinvestment for fintech startups thus creating a richer investment climate that will support innovation and company scaleup across borders fine wi...
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ai engineering suite to support agile efficient software engineering
ai4softeng represents an excellent chemistry of 13 partners including experts and practitioners in modeldrive software engineering and ai engineering particularly llms from across europe and usa with four usecases from software development healthcare cyberphysical system involving multiarchitectural and resourceconstra...
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dangerous liaisons classical antiquity and lgbtq movements in greece the uk and the us
contemporary lesbian gay bisexual trans and queer lgbtq movements actively engage with the past through archival selection and historiographical accounts they construct interpret and preserve their collective identities the proposed project homoclassicisms focuses specifically on the cases of lgbtq movements in greece ...
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the first ivdrapproved commercial software solutions for aipowered rnabased companion and precision cancer diagnostics of acute myeloid leukaemia and bladder cancer
qlucore is developing visualisationbased analytical solutions with an established position in the nextgeneration sequencing ngs market as pioneers in rnadata analysis we aim to revolutionise the field of companion and clinical diagnostics by developing software platforms integrating aipowered machinelearning classifica...
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mechanisms of human cotranslational quality control and its role in neural tissue
ribosomeassociated quality control rqc is crucial for degrading truncated nascent proteins produced on aberrant mrnas this is done by elongation of the nascent chain on the large ribosomal subunit in the absence of mrna and the small ribosomal subunit cat tailing and by marking the nascent chain for degradation mutatio...
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the spatial organization of gene regulation in embryonic development
master transcription factors tfs cooperate with chromatin in regulating genomic activity in animal development and stress response local clustering of tfs into dense submicrometer size condensates is emerging as a key feature of transcriptional regulation this includes intranuclear condensates formed by pioneer tfs dur...
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development of functional fish feed based on bioactive compounds of marine and herbal origin
feedactiv focuses on the development of innovative aquaculture feed based on natural bioactive compounds that boost the immune system of farmed fish various species of marine microalgae as well as seaweed and land based herbal plants are going to be used as enrichment of the fish feed and hopefully as partial fishmeal ...
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magnificoprecommercialization of multifunctional targeted mricontrast enhancing agents for brain research
magnetic resonance imaging mri is a nondamaging and noninvasive imaging modality with the abilities to effortlessly image the entire brain at any depth however mri provides images with low contrast and very poor resolution and these are but an indirect description of features in the tissue eg cells because mri images w...
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building vascular networks and bloodbrainbarriers through a biomimetic manufacturing technology for the fabrication of human tissues and organs
tenths of millions of people with organ failures or suffering from degenerative diseases are waiting for a novel cellular therapy or for a transplant of a donor compatible organ and the immense majority of these patients will die before receiving the tissue or organ they need despite the significant advances in tissue ...
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democracy autocracy and international cooperation
one of the most consistent findings in the study of world politics is the positive relationship between democratic regimes and international cooperation yet events in recent years suggest a more complicated picture several democracies have withered in their support for international organizations while autocracies simu...
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strengthening research and innovation excellence in autonomous aerial systems
built on lessons learned and experience gained upon successful implementation of twinning project aerotwin this proposal is conceived as an effort to stream aerotwin positive effects on a network of higher education institutions heis from croatia and bosnia and herzegovina in order to enlarge capacity for research and ...
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probing the finelyresolved 100 tev gammaray sky for ultraheavy dark matter
dark100 will shine a light into an underexplored dark matter particle mass range driven by recent theoretical developments both in tools and motivation dark100 will search for dark matter particles between 100 tev and several tens of pev leveraging novel costeffective telescope technology dark100 will deploy an array o...
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the roots of civility french renaissance literature as a laboratory of modern civility
renaissance men and women had a passion for virtue and a genius for cruelty they had wonderful manners and barbaric inclinations lovely clothes and terrible diseases can they really teach us something about civility i think they can they were made of contradictions and so are we and both we and they dream of a society ...
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the role of structural variation in adaptive radiation
long distance dispersal and adaptive radiation events have produced some of the most species rich ecosystems in the world while colonizing lineages can adapt to new environments the selective processes by which they do so is unclear given the paucity of genetic diversity in founder populations recent interest in the ev...
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formalizing verifying and applying isa security guarantees as universal contracts
the instruction set architecture isa is the interface that processor hardware offers to software developers current isas do not explicitly specify the security properties guaranteed by that interface so that for example recent severe microarchitectural sidechannel vulnerabilities like spectre did not even violate the s...
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targetting neutrophilmediated neurotoxicity for the treatment of alzheimers disease
with the neutrad erc poc project we present the first diseasemodifying alzheimers disease ad drugs that abrogate leukocytemediated neurotoxicity and represent a novel class of drugs in the treatment of adad is a neurological disorder characterized by progressive deterioration of cognitive function and leads to death wi...
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a leap towards sae l4 automated driving features
the introduction of connected cooperative and automated mobility ccam can make a significant improvement to logistic chains the modi project will identify and largely resolve barriers on confined areas and on public roads for sae l4 ccam vehicles on the corridor from rotterdam to oslo and demonstrate the solutions coor...
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facilitating innovations for resilient livestock farming systems
the overall objective of relivestock is to evaluate and mobilize the adoption of innovative practices applied crossscale animal herd farm sector and region to reduce ghg emissions from livestock farming systems and increase their capacity to dealing with potential climate change impacts to reach our aim relivestock hav...
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life cycle center for power cable diagnosis
the eu goals for the clean energy transition require at least a 55 reduction in greenhouse gas emissions from 1990 levels by 2030 according to the fit for 55 package to achieve these goals electricity grids will be required to operate in an overall context of 50 electricity production from res of any scale by 2030 the ...
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environmental gentrification and emerging collectives in uncertain times
in the global north in the face of the looming threats of manifold environmental crises there is an increasing sense of urgency to enhance cities sustainability yet topdown paradigms of urban regeneration can contribute creating enclaves of environmental privilege thereby excluding lower income and minority groups from...