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| 2-LTR circle formation REACT:R-HSA-164843 |
| 2-Oxocarboxylic acid metabolism KEGG:hsa01210 |
| 5-Phosphoribose 1-diphosphate biosynthesis REACT:R-HSA-73843 |
| Abacavir metabolism REACT:R-HSA-2161541 |
| Abacavir transmembrane transport REACT:R-HSA-2161517 |
| Abacavir transport and metabolism REACT:R-HSA-2161522 |
| Abasic sugar-phosphate removal via the single-nucleotide replacement pathway REACT:R-HSA-73930 |
| ABC-family proteins mediated transport REACT:R-HSA-382556 |
| ABC transporter disorders REACT:R-HSA-5619084 |
| ABC transporters KEGG:hsa02010 |
| ABC transporters in lipid homeostasis REACT:R-HSA-1369062 |
| Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate REACT:R-HSA-2978092 |
| Abortive elongation of HIV-1 transcript in the absence of Tat REACT:R-HSA-167242 |
| Acetylation REACT:R-HSA-156582 |
| Acetylcholine Binding And Downstream Events REACT:R-HSA-181431 |
| Acetylcholine Neurotransmitter Release Cycle REACT:R-HSA-264642 |
| Acetylcholine regulates insulin secretion REACT:R-HSA-399997 |
| Acrosome Reaction REACT:R-HSA-1300645 |
| Activated NOTCH1 Transmits Signal to the Nucleus REACT:R-HSA-2122948 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 REACT:R-HSA-5625886 |
| Activated point mutants of FGFR2 REACT:R-HSA-2033519 |
| activated TAK1 mediates p38 MAPK activation REACT:R-HSA-450302 |
| Activated TLR4 signalling REACT:R-HSA-166054 |
| Activation and oligomerization of BAK protein REACT:R-HSA-111452 |
| Activation, myristolyation of BID and translocation to mitochondria REACT:R-HSA-75108 |
| Activation of AKT2 REACT:R-HSA-165158 |
| Activation of AMPA receptors REACT:R-HSA-399710 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis REACT:R-HSA-5617472 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins REACT:R-HSA-176814 |
| Activation of ATR in response to replication stress REACT:R-HSA-176187 |
| Activation of BAD and translocation to mitochondria REACT:R-HSA-111447 |
| Activation of BH3-only proteins REACT:R-HSA-114452 |
| Activation of BIM and translocation to mitochondria REACT:R-HSA-111446 |
| Activation of BMF and translocation to mitochondria REACT:R-HSA-139910 |
| Activation of C3 and C5 REACT:R-HSA-174577 |
| Activation of CaMK IV REACT:R-HSA-442745 |
| Activation of Ca-permeable Kainate Receptor REACT:R-HSA-451308 |
| Activation of caspases through apoptosome-mediated cleavage REACT:R-HSA-111459 |
| Activation of DNA fragmentation factor REACT:R-HSA-211227 |
| Activation of GABAB receptors REACT:R-HSA-991365 |
| Activation of gene expression by SREBF (SREBP) REACT:R-HSA-2426168 |
| Activation of G protein gated Potassium channels REACT:R-HSA-1296041 |
| Activation of HOX genes during differentiation REACT:R-HSA-5619507 |
| Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon REACT:R-HSA-936964 |
| Activation of Kainate Receptors upon glutamate binding REACT:R-HSA-451326 |
| Activation of Matrix Metalloproteinases REACT:R-HSA-1592389 |
| Activation of Na-permeable Kainate Receptors REACT:R-HSA-451307 |
| Activation of NF-kappaB in B cells REACT:R-HSA-1169091 |
| Activation of Nicotinic Acetylcholine Receptors REACT:R-HSA-629602 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 REACT:R-HSA-2980767 |
| Activation of NMDA receptor upon glutamate binding and postsynaptic events REACT:R-HSA-442755 |
| Activation of NOXA and translocation to mitochondria REACT:R-HSA-111448 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation REACT:R-HSA-2151209 |
| Activation of PUMA and translocation to mitochondria REACT:R-HSA-139915 |
| Activation of Rac REACT:R-HSA-428540 |
| Activation of RAS in B cells REACT:R-HSA-1169092 |
| Activation of SMO REACT:R-HSA-5635838 |
| Activation of the AP-1 family of transcription factors REACT:R-HSA-450341 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S REACT:R-HSA-72662 |
| Activation of the phototransduction cascade REACT:R-HSA-2485179 |
| Activation of the pre-replicative complex REACT:R-HSA-68962 |
| Activation of the TFAP2 (AP-2) family of transcription factors REACT:R-HSA-8866907 |
| Activation of TRKA receptors REACT:R-HSA-187015 |
| Activation, translocation and oligomerization of BAX REACT:R-HSA-114294 |
| Activin signaling KEGG:hsa_M00681 |
| Acute myeloid leukemia KEGG:hsa05221 |
| Acyl chain remodeling of CL REACT:R-HSA-1482798 |
| Acyl chain remodeling of DAG and TAG REACT:R-HSA-1482883 |
| Acyl chain remodelling of PC REACT:R-HSA-1482788 |
| Acyl chain remodelling of PE REACT:R-HSA-1482839 |
| Acyl chain remodelling of PG REACT:R-HSA-1482925 |
| Acyl chain remodelling of PI REACT:R-HSA-1482922 |
| Acyl chain remodelling of PS REACT:R-HSA-1482801 |
| Acylglycerol degradation KEGG:hsa_M00098 |
| Adaptive Immune System REACT:R-HSA-1280218 |
| Adenine ribonucleotide biosynthesis, IMP => ADP,ATP KEGG:hsa_M00049 |
| Adenosine P1 receptors REACT:R-HSA-417973 |
| Adenylate cyclase activating pathway REACT:R-HSA-170660 |
| Adenylate cyclase inhibitory pathway REACT:R-HSA-170670 |
| Adherens junction KEGG:hsa04520 |
| Adherens junctions interactions REACT:R-HSA-418990 |
| Adipocytokine signaling pathway KEGG:hsa04920 |
| ADP signalling through P2Y purinoceptor 1 REACT:R-HSA-418592 |
| ADP signalling through P2Y purinoceptor 12 REACT:R-HSA-392170 |
| Adrenaline,noradrenaline inhibits insulin secretion REACT:R-HSA-400042 |
| Adrenaline signalling through Alpha-2 adrenergic receptor REACT:R-HSA-392023 |
| Adrenergic signaling in cardiomyocytes KEGG:hsa04261 |
| Adrenoceptors REACT:R-HSA-390696 |
| Advanced glycosylation endproduct receptor signaling REACT:R-HSA-879415 |
| Aflatoxin activation and detoxification REACT:R-HSA-5423646 |
| African trypanosomiasis KEGG:hsa05143 |
| AGE-RAGE signaling pathway in diabetic complications KEGG:hsa04933 |
| Agmatine biosynthesis REACT:R-HSA-351143 |
| AKT-mediated inactivation of FOXO1A REACT:R-HSA-211163 |
| AKT phosphorylates targets in the cytosol REACT:R-HSA-198323 |
| AKT phosphorylates targets in the nucleus REACT:R-HSA-198693 |
| Alanine, aspartate and glutamate metabolism KEGG:hsa00250 |
| Alcoholism KEGG:hsa05034 |
| Aldosterone-regulated sodium reabsorption KEGG:hsa04960 |
| Aldosterone synthesis and secretion KEGG:hsa04925 |
| ALKBH2 mediated reversal of alkylation damage REACT:R-HSA-112122 |
| ALKBH3 mediated reversal of alkylation damage REACT:R-HSA-112126 |
| Allograft rejection KEGG:hsa05330 |
| Alpha-defensins REACT:R-HSA-1462054 |
| alpha-linolenic acid (ALA) metabolism REACT:R-HSA-2046106 |
| alpha-Linolenic acid metabolism KEGG:hsa00592 |
| alpha-linolenic (omega3) and linoleic (omega6) acid metabolism REACT:R-HSA-2046104 |
| Alpha-oxidation of phytanate REACT:R-HSA-389599 |
| Alternative complement activation REACT:R-HSA-173736 |
| Alzheimer's disease KEGG:hsa05010 |
| AMER1 mutants destabilize the destruction complex REACT:R-HSA-4839748 |
| Amine-derived hormones REACT:R-HSA-209776 |
| Amine ligand-binding receptors REACT:R-HSA-375280 |
| Amine Oxidase reactions REACT:R-HSA-140179 |
| Amino Acid conjugation REACT:R-HSA-156587 |
| Amino acid synthesis and interconversion (transamination) REACT:R-HSA-70614 |
| Amino acid transport across the plasma membrane REACT:R-HSA-352230 |
| Aminoacyl-tRNA biosynthesis KEGG:hsa00970 |
| Aminoacyl-tRNA biosynthesis, eukaryotes KEGG:hsa_M00359 |
| Amino sugar and nucleotide sugar metabolism KEGG:hsa00520 |
| Amoebiasis KEGG:hsa05146 |
| Amphetamine addiction KEGG:hsa05031 |
| AMPK inhibits chREBP transcriptional activation activity REACT:R-HSA-163680 |
| AMPK signaling pathway KEGG:hsa04152 |
| Amplification of signal from the kinetochores REACT:R-HSA-141424 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal REACT:R-HSA-141444 |
| Amyloid fiber formation REACT:R-HSA-977225 |
| Amyotrophic lateral sclerosis (ALS) KEGG:hsa05014 |
| Anchoring fibril formation REACT:R-HSA-2214320 |
| Anchoring of the basal body to the plasma membrane REACT:R-HSA-5620912 |
| Androgen biosynthesis REACT:R-HSA-193048 |
| Antagonism of Activin by Follistatin REACT:R-HSA-2473224 |
| Antifolate resistance KEGG:hsa01523 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers REACT:R-HSA-983695 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC REACT:R-HSA-983170 |
| Antigen processing and presentation KEGG:hsa04612 |
| Antigen processing-Cross presentation REACT:R-HSA-1236975 |
| Antigen processing: Ubiquitination & Proteasome degradation REACT:R-HSA-983168 |
| Antimicrobial peptides REACT:R-HSA-6803157 |
| Antiviral mechanism by IFN-stimulated genes REACT:R-HSA-1169410 |
| APC/C:Cdc20 mediated degradation of Cyclin B REACT:R-HSA-174048 |
| APC/C:Cdc20 mediated degradation of mitotic proteins REACT:R-HSA-176409 |
| APC/C:Cdc20 mediated degradation of Securin REACT:R-HSA-174154 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 REACT:R-HSA-174178 |
| APC/C complex KEGG:hsa_M00389 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint REACT:R-HSA-179419 |
| APC-Cdc20 mediated degradation of Nek2A REACT:R-HSA-179409 |
| APC/C-mediated degradation of cell cycle proteins REACT:R-HSA-174143 |
| APC truncation mutants are not K63 polyubiquitinated REACT:R-HSA-5467333 |
| APC truncation mutants have impaired AXIN binding REACT:R-HSA-5467337 |
| Apelin signaling pathway KEGG:hsa04371 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway REACT:R-HSA-5649702 |
| APOBEC3G mediated resistance to HIV-1 infection REACT:R-HSA-180689 |
| Apoptosis KEGG:hsa04210 |
| Apoptosis REACT:R-HSA-109581 |
| Apoptosis induced DNA fragmentation REACT:R-HSA-140342 |
| Apoptosis - multiple species KEGG:hsa04215 |
| Apoptotic cleavage of cell adhesion proteins REACT:R-HSA-351906 |
| Apoptotic cleavage of cellular proteins REACT:R-HSA-111465 |
| Apoptotic execution phase REACT:R-HSA-75153 |
| Apoptotic factor-mediated response REACT:R-HSA-111471 |
| Apoptotic machinery KEGG:hsa_M00685 |
| Aquaporin-mediated transport REACT:R-HSA-445717 |
| Arachidonate production from DAG REACT:R-HSA-426048 |
| Arachidonic acid metabolism KEGG:hsa00590 |
| Arachidonic acid metabolism REACT:R-HSA-2142753 |
| Arginine and proline metabolism KEGG:hsa00330 |
| Arginine biosynthesis KEGG:hsa00220 |
| ARL13B-mediated ciliary trafficking of INPP5E REACT:R-HSA-5624958 |
| ARMS-mediated activation REACT:R-HSA-170984 |
| Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 REACT:R-HSA-211957 |
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) KEGG:hsa05412 |
| Aryl hydrocarbon receptor signalling REACT:R-HSA-8937144 |
| Ascorbate and aldarate metabolism KEGG:hsa00053 |
| Asparagine N-linked glycosylation REACT:R-HSA-446203 |
| Assembly of collagen fibrils and other multimeric structures REACT:R-HSA-2022090 |
| Assembly Of The HIV Virion REACT:R-HSA-175474 |
| Assembly of the ORC complex at the origin of replication REACT:R-HSA-68616 |
| Assembly of the pre-replicative complex REACT:R-HSA-68867 |
| Assembly of Viral Components at the Budding Site REACT:R-HSA-168316 |
| Association of licensing factors with the pre-replicative complex REACT:R-HSA-69298 |
| Association of TriC/CCT with target proteins during biosynthesis REACT:R-HSA-390471 |
| Asthma KEGG:hsa05310 |
| Astrocytic Glutamate-Glutamine Uptake And Metabolism REACT:R-HSA-210455 |
| Asymmetric localization of PCP proteins REACT:R-HSA-4608870 |
| A tetrasaccharide linker sequence is required for GAG synthesis REACT:R-HSA-1971475 |
| ATF4 activates genes REACT:R-HSA-380994 |
| ATF6 (ATF6-alpha) activates chaperone genes REACT:R-HSA-381183 |
| ATF6 (ATF6-alpha) activates chaperones REACT:R-HSA-381033 |
| ATP sensitive Potassium channels REACT:R-HSA-1296025 |
| Attachment of GPI anchor to uPAR REACT:R-HSA-162791 |
| Attenuation phase REACT:R-HSA-3371568 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA REACT:R-HSA-450408 |
| AURKA Activation by TPX2 REACT:R-HSA-8854518 |
| Autodegradation of Cdh1 by Cdh1:APC/C REACT:R-HSA-174084 |
| Autodegradation of the E3 ubiquitin ligase COP1 REACT:R-HSA-349425 |
| Autoimmune thyroid disease KEGG:hsa05320 |
| Autointegration results in viral DNA circles REACT:R-HSA-177539 |
| Autophagy - animal KEGG:hsa04140 |
| Autophagy - other KEGG:hsa04136 |
| AXIN missense mutants destabilize the destruction complex REACT:R-HSA-5467340 |
| AXIN mutants destabilize the destruction complex, activating WNT signaling REACT:R-HSA-4839735 |
| Axonal growth inhibition (RHOA activation) REACT:R-HSA-193634 |
| Axonal growth stimulation REACT:R-HSA-209563 |
| Axon guidance KEGG:hsa04360 |
| Axon guidance REACT:R-HSA-422475 |
| Bacterial invasion of epithelial cells KEGG:hsa05100 |
| Basal cell carcinoma KEGG:hsa05217 |
| Basal transcription factors KEGG:hsa03022 |
| Base excision repair KEGG:hsa03410 |
| Base Excision Repair REACT:R-HSA-73884 |
| Base-Excision Repair, AP Site Formation REACT:R-HSA-73929 |
| Basigin interactions REACT:R-HSA-210991 |
| BBSome-mediated cargo-targeting to cilium REACT:R-HSA-5620922 |
| B cell receptor signaling pathway KEGG:hsa04662 |
| BER complex KEGG:hsa_M00296 |
| beta-Alanine metabolism KEGG:hsa00410 |
| Beta-catenin independent WNT signaling REACT:R-HSA-3858494 |
| Beta-catenin phosphorylation cascade REACT:R-HSA-196299 |
| Beta defensins REACT:R-HSA-1461957 |
| betaKlotho-mediated ligand binding REACT:R-HSA-1307965 |
| beta-Oxidation KEGG:hsa_M00087 |
| beta-Oxidation, acyl-CoA synthesis KEGG:hsa_M00086 |
| Beta oxidation of butanoyl-CoA to acetyl-CoA REACT:R-HSA-77352 |
| Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA REACT:R-HSA-77346 |
| Beta oxidation of hexanoyl-CoA to butanoyl-CoA REACT:R-HSA-77350 |
| Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA REACT:R-HSA-77310 |
| Beta oxidation of myristoyl-CoA to lauroyl-CoA REACT:R-HSA-77285 |
| Beta oxidation of octanoyl-CoA to hexanoyl-CoA REACT:R-HSA-77348 |
| Beta oxidation of palmitoyl-CoA to myristoyl-CoA REACT:R-HSA-77305 |
| Beta-oxidation of pristanoyl-CoA REACT:R-HSA-389887 |
| Beta-oxidation of very long chain fatty acids REACT:R-HSA-390247 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members REACT:R-HSA-111453 |
| Bicarbonate transporters REACT:R-HSA-425381 |
| Bile acid and bile salt metabolism REACT:R-HSA-194068 |
| Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate KEGG:hsa_M00104 |
| Bile secretion KEGG:hsa04976 |
| Binding and entry of HIV virion REACT:R-HSA-173107 |
| Binding and Uptake of Ligands by Scavenger Receptors REACT:R-HSA-2173782 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters REACT:R-HSA-4411364 |
| Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB REACT:R-HSA-141333 |
| Biological oxidations REACT:R-HSA-211859 |
| Biosynthesis of A2E, implicated in retinal degradation REACT:R-HSA-2466712 |
| Biosynthesis of amino acids KEGG:hsa01230 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein REACT:R-HSA-446193 |
| Biosynthesis of unsaturated fatty acids KEGG:hsa01040 |
| Biotin metabolism KEGG:hsa00780 |
| Biotin transport and metabolism REACT:R-HSA-196780 |
| Bladder cancer KEGG:hsa05219 |
| Bloom's syndrome complex KEGG:hsa_M00414 |
| BMAL1:CLOCK,NPAS2 activates circadian gene expression REACT:R-HSA-1368108 |
| BMP signaling KEGG:hsa_M00679 |
| Branched-chain amino acid catabolism REACT:R-HSA-70895 |
| BRCA1-associated genome surveillance complex (BASC) KEGG:hsa_M00295 |
| Breakdown of the nuclear lamina REACT:R-HSA-352238 |
| Breast cancer KEGG:hsa05224 |
| Budding REACT:R-HSA-168302 |
| Budding and maturation of HIV virion REACT:R-HSA-162588 |
| Butanoate metabolism KEGG:hsa00650 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA REACT:R-HSA-450385 |
| Butyrophilin (BTN) family interactions REACT:R-HSA-8851680 |
| B-WICH complex positively regulates rRNA expression REACT:R-HSA-5250924 |
| C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone KEGG:hsa_M00110 |
| C1-unit interconversion, eukaryotes KEGG:hsa_M00141 |
| C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone KEGG:hsa_M00108 |
| C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone KEGG:hsa_M00109 |
| C5 isoprenoid biosynthesis, mevalonate pathway KEGG:hsa_M00095 |
| C6 deamination of adenosine REACT:R-HSA-75102 |
| Ca2+ activated K+ channels REACT:R-HSA-1296052 |
| Ca2+ pathway REACT:R-HSA-4086398 |
| Ca-dependent events REACT:R-HSA-111996 |
| Caffeine metabolism KEGG:hsa00232 |
| Calcitonin-like ligand receptors REACT:R-HSA-419812 |
| Calcium signaling pathway KEGG:hsa04020 |
| Calmodulin induced events REACT:R-HSA-111933 |
| Calnexin/calreticulin cycle REACT:R-HSA-901042 |
| CaMK IV-mediated phosphorylation of CREB REACT:R-HSA-111932 |
| CaM pathway REACT:R-HSA-111997 |
| Cam-PDE 1 activation REACT:R-HSA-111957 |
| cAMP signaling KEGG:hsa_M00695 |
| cAMP signaling pathway KEGG:hsa04024 |
| Cap binding complex KEGG:hsa_M00399 |
| Cap-dependent Translation Initiation REACT:R-HSA-72737 |
| Carbohydrate digestion and absorption KEGG:hsa04973 |
| Carbon metabolism KEGG:hsa01200 |
| Cardiac conduction REACT:R-HSA-5576891 |
| Cardiac muscle contraction KEGG:hsa04260 |
| Cargo concentration in the ER REACT:R-HSA-5694530 |
| Cargo recognition for clathrin-mediated endocytosis REACT:R-HSA-8856825 |
| Cargo trafficking to the periciliary membrane REACT:R-HSA-5620920 |
| Carnitine synthesis REACT:R-HSA-71262 |
| CASP8 activity is inhibited REACT:R-HSA-5218900 |
| Caspase activation via extrinsic apoptotic signalling pathway REACT:R-HSA-5357769 |
| Caspase-mediated cleavage of cytoskeletal proteins REACT:R-HSA-264870 |
| Catabolism of glucuronate to xylulose-5-phosphate REACT:R-HSA-5661270 |
| Catecholamine biosynthesis REACT:R-HSA-209905 |
| Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline KEGG:hsa_M00042 |
| Cation-coupled Chloride cotransporters REACT:R-HSA-426117 |
| CD209 (DC-SIGN) signaling REACT:R-HSA-5621575 |
| CD22 mediated BCR regulation REACT:R-HSA-5690714 |
| CD28 co-stimulation REACT:R-HSA-389356 |
| CD28 dependent PI3K/Akt signaling REACT:R-HSA-389357 |
| CD28 dependent Vav1 pathway REACT:R-HSA-389359 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A REACT:R-HSA-174184 |
| CDC6 association with the ORC:origin complex REACT:R-HSA-68689 |
| CDK-mediated phosphorylation and removal of Cdc6 REACT:R-HSA-69017 |
| CDO in myogenesis REACT:R-HSA-375170 |
| CDT1 association with the CDC6:ORC:origin complex REACT:R-HSA-68827 |
| Cell adhesion molecules (CAMs) KEGG:hsa04514 |
| Cell-Cell communication REACT:R-HSA-1500931 |
| Cell-cell junction organization REACT:R-HSA-421270 |
| Cell cycle KEGG:hsa04110 |
| Cell Cycle REACT:R-HSA-1640170 |
| Cell Cycle Checkpoints REACT:R-HSA-69620 |
| Cell cycle - G1/S transition KEGG:hsa_M00692 |
| Cell cycle - G2/M transition KEGG:hsa_M00693 |
| Cell Cycle, Mitotic REACT:R-HSA-69278 |
| Cell death signalling via NRAGE, NRIF and NADE REACT:R-HSA-204998 |
| Cell-extracellular matrix interactions REACT:R-HSA-446353 |
| Cell junction organization REACT:R-HSA-446728 |
| Cell redox homeostasis REACT:R-HSA-1222541 |
| Cell surface interactions at the vascular wall REACT:R-HSA-202733 |
| Cellular responses to stress REACT:R-HSA-2262752 |
| Cellular response to heat stress REACT:R-HSA-3371556 |
| Cellular response to hypoxia REACT:R-HSA-2262749 |
| Cellular Senescence REACT:R-HSA-2559583 |
| Central carbon metabolism in cancer KEGG:hsa05230 |
| Centrosome maturation REACT:R-HSA-380287 |
| Ceramide biosynthesis KEGG:hsa_M00094 |
| Ceramide signalling REACT:R-HSA-193681 |
| cGMP effects REACT:R-HSA-418457 |
| cGMP-PKG signaling pathway KEGG:hsa04022 |
| cGMP signaling KEGG:hsa_M00694 |
| Chagas disease (American trypanosomiasis) KEGG:hsa05142 |
| Chaperonin-mediated protein folding REACT:R-HSA-390466 |
| Chemical carcinogenesis KEGG:hsa05204 |
| Chemokine receptors bind chemokines REACT:R-HSA-380108 |
| Chemokine signaling pathway KEGG:hsa04062 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex REACT:R-HSA-75035 |
| CHL1 interactions REACT:R-HSA-447041 |
| Cholecalciferol biosynthesis KEGG:hsa_M00103 |
| Cholesterol biosynthesis REACT:R-HSA-191273 |
| Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol KEGG:hsa_M00101 |
| Cholesterol biosynthesis via desmosterol REACT:R-HSA-6807047 |
| Cholesterol biosynthesis via lathosterol REACT:R-HSA-6807062 |
| Choline catabolism REACT:R-HSA-6798163 |
| Choline metabolism in cancer KEGG:hsa05231 |
| Cholinergic synapse KEGG:hsa04725 |
| Chondroitin sulfate biosynthesis REACT:R-HSA-2022870 |
| Chondroitin sulfate degradation KEGG:hsa_M00077 |
| Chondroitin sulfate/dermatan sulfate metabolism REACT:R-HSA-1793185 |
| ChREBP activates metabolic gene expression REACT:R-HSA-163765 |
| Chromatin modifying enzymes REACT:R-HSA-3247509 |
| Chromatin organization REACT:R-HSA-4839726 |
| Chromosome Maintenance REACT:R-HSA-73886 |
| Chronic myeloid leukemia KEGG:hsa05220 |
| Chylomicron-mediated lipid transport REACT:R-HSA-174800 |
| Cilium Assembly REACT:R-HSA-5617833 |
| Circadian Clock REACT:R-HSA-400253 |
| Circadian entrainment KEGG:hsa04713 |
| Circadian rhythm KEGG:hsa04710 |
| Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate KEGG:hsa_M00010 |
| Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate KEGG:hsa_M00011 |
| Citrate cycle (TCA cycle) KEGG:hsa00020 |
| Citrate cycle (TCA cycle, Krebs cycle) KEGG:hsa_M00009 |
| Citric acid cycle (TCA cycle) REACT:R-HSA-71403 |
| Class A/1 (Rhodopsin-like receptors) REACT:R-HSA-373076 |
| Class B/2 (Secretin family receptors) REACT:R-HSA-373080 |
| Class C/3 (Metabotropic glutamate/pheromone receptors) REACT:R-HSA-420499 |
| Classical antibody-mediated complement activation REACT:R-HSA-173623 |
| Classical Kir channels REACT:R-HSA-1296053 |
| Class II GLUTs REACT:R-HSA-428776 |
| Class I MHC mediated antigen processing & presentation REACT:R-HSA-983169 |
| Clathrin derived vesicle budding REACT:R-HSA-421837 |
| Clathrin-mediated endocytosis REACT:R-HSA-8856828 |
| Clearance of Nuclear Envelope Membranes from Chromatin REACT:R-HSA-2993913 |
| Cleavage of Growing Transcript in the Termination Region REACT:R-HSA-109688 |
| Cleavage of the damaged purine REACT:R-HSA-110331 |
| Cleavage of the damaged pyrimidine REACT:R-HSA-110329 |
| CLEC7A (Dectin-1) induces NFAT activation REACT:R-HSA-5607763 |
| CLEC7A (Dectin-1) signaling REACT:R-HSA-5607764 |
| CLEC7A/inflammasome pathway REACT:R-HSA-5660668 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism REACT:R-HSA-196741 |
| Cocaine addiction KEGG:hsa05030 |
| Coenzyme A biosynthesis REACT:R-HSA-196783 |
| Coenzyme A biosynthesis, pantothenate => CoA KEGG:hsa_M00120 |
| Cohesin Loading onto Chromatin REACT:R-HSA-2470946 |
| Collagen biosynthesis and modifying enzymes REACT:R-HSA-1650814 |
| Collagen chain trimerization REACT:R-HSA-8948216 |
| Collagen degradation REACT:R-HSA-1442490 |
| Collagen formation REACT:R-HSA-1474290 |
| Collecting duct acid secretion KEGG:hsa04966 |
| Colorectal cancer KEGG:hsa05210 |
| Common Pathway of Fibrin Clot Formation REACT:R-HSA-140875 |
| Complement and coagulation cascades KEGG:hsa04610 |
| Complement cascade REACT:R-HSA-166658 |
| Complex I biogenesis REACT:R-HSA-6799198 |
| Condensation of Prometaphase Chromosomes REACT:R-HSA-2514853 |
| Condensation of Prophase Chromosomes REACT:R-HSA-2299718 |
| Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate KEGG:hsa_M00106 |
| Conjugation of benzoate with glycine REACT:R-HSA-177135 |
| Conjugation of carboxylic acids REACT:R-HSA-159424 |
| Conjugation of phenylacetate with glutamine REACT:R-HSA-177162 |
| Conjugation of salicylate with glycine REACT:R-HSA-177128 |
| Constitutive Signaling by Aberrant PI3K in Cancer REACT:R-HSA-2219530 |
| Constitutive Signaling by AKT1 E17K in Cancer REACT:R-HSA-5674400 |
| Constitutive Signaling by EGFRvIII REACT:R-HSA-5637810 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants REACT:R-HSA-1236382 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants REACT:R-HSA-2691232 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants REACT:R-HSA-2894862 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants REACT:R-HSA-2644606 |
| Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant REACT:R-HSA-2660826 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase REACT:R-HSA-176407 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding REACT:R-HSA-6814122 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding REACT:R-HSA-389958 |
| COPI-dependent Golgi-to-ER retrograde traffic REACT:R-HSA-6811434 |
| COPII (Coat Protein 2) Mediated Vesicle Transport REACT:R-HSA-204005 |
| COPII complex KEGG:hsa_M00404 |
| COPI-independent Golgi-to-ER retrograde traffic REACT:R-HSA-6811436 |
| COPI-mediated anterograde transport REACT:R-HSA-6807878 |
| Costimulation by the CD28 family REACT:R-HSA-388841 |
| COX reactions REACT:R-HSA-140180 |
| Creatine metabolism REACT:R-HSA-71288 |
| Creatine pathway KEGG:hsa_M00047 |
| Creation of C4 and C2 activators REACT:R-HSA-166786 |
| CREB phosphorylation REACT:R-HSA-199920 |
| CREB phosphorylation through the activation of Adenylate Cyclase REACT:R-HSA-442720 |
| CREB phosphorylation through the activation of CaMKII REACT:R-HSA-442729 |
| CREB phosphorylation through the activation of CaMKK REACT:R-HSA-442717 |
| CREB phosphorylation through the activation of Ras REACT:R-HSA-442742 |
| CRMPs in Sema3A signaling REACT:R-HSA-399956 |
| cRNA Synthesis REACT:R-HSA-192869 |
| Crosslinking of collagen fibrils REACT:R-HSA-2243919 |
| Cross-presentation of particulate exogenous antigens (phagosomes) REACT:R-HSA-1236973 |
| Cross-presentation of soluble exogenous antigens (endosomes) REACT:R-HSA-1236978 |
| CS/DS degradation REACT:R-HSA-2024101 |
| c-src mediated regulation of Cx43 function and closure of gap junctions REACT:R-HSA-191647 |
| CTLA4 inhibitory signaling REACT:R-HSA-389513 |
| C-type lectin receptors (CLRs) REACT:R-HSA-5621481 |
| Cul3-SPOP complex KEGG:hsa_M00384 |
| Cul4-DDB1-CSA complex KEGG:hsa_M00386 |
| Cul4-DDB1-DDB2 complex KEGG:hsa_M00385 |
| Cyclin A/B1 associated events during G2/M transition REACT:R-HSA-69273 |
| Cyclin A:Cdk2-associated events at S phase entry REACT:R-HSA-69656 |
| Cyclin B2 mediated events REACT:R-HSA-157881 |
| Cyclin D associated events in G1 REACT:R-HSA-69231 |
| Cyclin E associated events during G1/S transition REACT:R-HSA-69202 |
| CYP2E1 reactions REACT:R-HSA-211999 |
| Cysteine and methionine metabolism KEGG:hsa00270 |
| Cysteine biosynthesis, homocysteine + serine => cysteine KEGG:hsa_M00338 |
| Cysteine formation from homocysteine REACT:R-HSA-1614603 |
| Cytochrome bc1 complex KEGG:hsa_M00152 |
| Cytochrome bc1 complex respiratory unit KEGG:hsa_M00151 |
| Cytochrome c-mediated apoptotic response REACT:R-HSA-111461 |
| Cytochrome c oxidase KEGG:hsa_M00154 |
| Cytochrome P450 - arranged by substrate type REACT:R-HSA-211897 |
| Cytokine-cytokine receptor interaction KEGG:hsa04060 |
| Cytokine Signaling in Immune system REACT:R-HSA-1280215 |
| Cytosolic DNA-sensing pathway KEGG:hsa04623 |
| Cytosolic iron-sulfur cluster assembly REACT:R-HSA-2564830 |
| Cytosolic sensors of pathogen-associated DNA REACT:R-HSA-1834949 |
| Cytosolic sulfonation of small molecules REACT:R-HSA-156584 |
| Cytosolic tRNA aminoacylation REACT:R-HSA-379716 |
| DAG and IP3 signaling REACT:R-HSA-1489509 |
| DAP12 interactions REACT:R-HSA-2172127 |
| DAP12 signaling REACT:R-HSA-2424491 |
| D-Arginine and D-ornithine metabolism KEGG:hsa00472 |
| DARPP-32 events REACT:R-HSA-180024 |
| DCC mediated attractive signaling REACT:R-HSA-418885 |
| Deactivation of the beta-catenin transactivating complex REACT:R-HSA-3769402 |
| Deadenylation-dependent mRNA decay REACT:R-HSA-429914 |
| Deadenylation of mRNA REACT:R-HSA-429947 |
| Death Receptor Signalling REACT:R-HSA-73887 |
| Decapping complex KEGG:hsa_M00395 |
| Dectin-1 mediated noncanonical NF-kB signaling REACT:R-HSA-5607761 |
| Dectin-2 family REACT:R-HSA-5621480 |
| Defective ABCA12 causes autosomal recessive congenital ichthyosis type 4B REACT:R-HSA-5682294 |
| Defective ABCA1 causes Tangier disease REACT:R-HSA-5682113 |
| Defective ABCA3 causes pulmonary surfactant metabolism dysfunction 3 (SMDP3) REACT:R-HSA-5688399 |
| Defective ABCA3 causes pulmonary surfactant metabolism dysfunction type 3 (SMDP3) REACT:R-HSA-5683678 |
| Defective ABCB11 causes progressive familial intrahepatic cholestasis 2 and benign recurrent intrahepatic cholestasis 2 REACT:R-HSA-5678520 |
| Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1 REACT:R-HSA-5678771 |
| Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7) REACT:R-HSA-5683371 |
| Defective ABCC2 causes Dubin-Johnson syndrome REACT:R-HSA-5679001 |
| Defective ABCC6 causes pseudoxanthoma elasticum (PXE) REACT:R-HSA-5690338 |
| Defective ABCC8 can cause hypoglycemias and hyperglycemias REACT:R-HSA-5683177 |
| Defective ABCC9 causes dilated cardiomyopathy 10, familial atrial fibrillation 12 and hypertrichotic osteochondrodysplasia REACT:R-HSA-5678420 |
| Defective ABCD1 causes adrenoleukodystrophy (ALD) REACT:R-HSA-5684045 |
| Defective ABCD4 causes methylmalonic aciduria and homocystinuria, cblj type (MAHCJ) REACT:R-HSA-5683329 |
| Defective ABCG5 causes sitosterolemia REACT:R-HSA-5679096 |
| Defective ABCG8 causes gallbladder disease 4 and sitosterolemia REACT:R-HSA-5679090 |
| Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) REACT:R-HSA-5579031 |
| Defective ACY1 causes encephalopathy REACT:R-HSA-5579007 |
| Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) REACT:R-HSA-5578997 |
| Defective ALG11 causes ALG11-CDG (CDG-1p) REACT:R-HSA-4551295 |
| Defective ALG12 causes ALG12-CDG (CDG-1g) REACT:R-HSA-4720489 |
| Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) REACT:R-HSA-5633231 |
| Defective ALG1 causes ALG1-CDG (CDG-1k) REACT:R-HSA-4549380 |
| Defective ALG2 causes ALG2-CDG (CDG-1i) REACT:R-HSA-4549349 |
| Defective ALG3 causes ALG3-CDG (CDG-1d) REACT:R-HSA-4720475 |
| Defective ALG6 causes ALG6-CDG (CDG-1c) REACT:R-HSA-4724289 |
| Defective ALG8 causes ALG8-CDG (CDG-1h) REACT:R-HSA-4724325 |
| Defective ALG9 causes ALG9-CDG (CDG-1l) REACT:R-HSA-4720454 |
| Defective AMN causes hereditary megaloblastic anemia 1 REACT:R-HSA-3359462 |
| Defective AVP causes neurohypophyseal diabetes insipidus (NDI) REACT:R-HSA-5619099 |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 REACT:R-HSA-4420332 |
| Defective B3GALTL causes Peters-plus syndrome (PpS) REACT:R-HSA-5083635 |
| Defective B3GAT3 causes JDSSDHD REACT:R-HSA-3560801 |
| Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) REACT:R-HSA-3656244 |
| Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) REACT:R-HSA-4793953 |
| Defective B4GALT7 causes EDS, progeroid type REACT:R-HSA-3560783 |
| Defective BTD causes biotidinase deficiency REACT:R-HSA-3371598 |
| Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) REACT:R-HSA-5083632 |
| Defective CD320 causes methylmalonic aciduria REACT:R-HSA-3359485 |
| Defective CFTR causes cystic fibrosis REACT:R-HSA-5678895 |
| Defective CHST14 causes EDS, musculocontractural type REACT:R-HSA-3595174 |
| Defective CHST3 causes SEDCJD REACT:R-HSA-3595172 |
| Defective CHST6 causes MCDC1 REACT:R-HSA-3656225 |
| Defective CHSY1 causes TPBS REACT:R-HSA-3595177 |
| Defective CP causes aceruloplasminemia (ACERULOP) REACT:R-HSA-5619060 |
| Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4) REACT:R-HSA-5688890 |
| Defective CSF2RB causes pulmonary surfactant metabolism dysfunction 5 (SMDP5) REACT:R-HSA-5688849 |
| Defective CUBN causes hereditary megaloblastic anemia 1 REACT:R-HSA-3359463 |
| Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR) REACT:R-HSA-5579026 |
| Defective CYP11B1 causes Adrenal hyperplasia 4 (AH4) REACT:R-HSA-5579017 |
| Defective CYP11B2 causes Corticosterone methyloxidase 1 deficiency (CMO-1 deficiency) REACT:R-HSA-5579009 |
| Defective CYP17A1 causes Adrenal hyperplasia 5 (AH5) REACT:R-HSA-5579028 |
| Defective CYP19A1 causes Aromatase excess syndrome (AEXS) REACT:R-HSA-5579030 |
| Defective CYP1B1 causes Glaucoma REACT:R-HSA-5579000 |
| Defective CYP21A2 causes Adrenal hyperplasia 3 (AH3) REACT:R-HSA-5579021 |
| Defective CYP24A1 causes Hypercalcemia, infantile (HCAI) REACT:R-HSA-5579010 |
| Defective CYP26B1 causes Radiohumeral fusions with other skeletal and craniofacial anomalies (RHFCA) REACT:R-HSA-5579015 |
| Defective CYP26C1 causes Focal facial dermal dysplasia 4 (FFDD4) REACT:R-HSA-5579004 |
| Defective CYP27A1 causes Cerebrotendinous xanthomatosis (CTX) REACT:R-HSA-5578996 |
| Defective CYP27B1 causes Rickets vitamin D-dependent 1A (VDDR1A) REACT:R-HSA-5579014 |
| Defective CYP2R1 causes Rickets vitamin D-dependent 1B (VDDR1B) REACT:R-HSA-5579027 |
| Defective CYP2U1 causes Spastic paraplegia 56, autosomal recessive (SPG56) REACT:R-HSA-5579011 |
| Defective CYP4F22 causes Ichthyosis, congenital, autosomal recessive 5 (ARCI5) REACT:R-HSA-5579005 |
| Defective CYP7B1 causes Spastic paraplegia 5A, autosomal recessive (SPG5A) and Congenital bile acid synthesis defect 3 (CBAS3) REACT:R-HSA-5579013 |
| Defective DHDDS causes retinitis pigmentosa 59 REACT:R-HSA-4755609 |
| Defective DOLK causes DOLK-CDG (CDG-1m) REACT:R-HSA-4755583 |
| Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 REACT:R-HSA-4549356 |
| Defective DPM1 causes DPM1-CDG (CDG-1e) REACT:R-HSA-4717374 |
| Defective DPM2 causes DPM2-CDG (CDG-1u) REACT:R-HSA-4719377 |
| Defective DPM3 causes DPM3-CDG (CDG-1o) REACT:R-HSA-4719360 |
| Defective EXT1 causes exostoses 1, TRPS2 and CHDS REACT:R-HSA-3656253 |
| Defective EXT2 causes exostoses 2 REACT:R-HSA-3656237 |
| Defective FMO3 causes Trimethylaminuria (TMAU) REACT:R-HSA-5579019 |
| Defective GALE can cause Epimerase-deficiency galactosemia (EDG) REACT:R-HSA-5609977 |
| Defective GALK1 can cause Galactosemia II (GALCT2) REACT:R-HSA-5609976 |
| Defective GALNT12 causes colorectal cancer 1 (CRCS1) REACT:R-HSA-5083636 |
| Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) REACT:R-HSA-5083625 |
| Defective GALT can cause Galactosemia REACT:R-HSA-5609978 |
| Defective GCK causes maturity-onset diabetes of the young 2 (MODY2) REACT:R-HSA-5619073 |
| Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) REACT:R-HSA-5578999 |
| Defective GFPT1 causes CMSTA1 REACT:R-HSA-4085023 |
| Defective GGT1 causes Glutathionuria (GLUTH) REACT:R-HSA-5579022 |
| Defective GIF causes intrinsic factor deficiency REACT:R-HSA-3359457 |
| Defective GNE causes sialuria, Nonaka myopathy and inclusion body myopathy 2 REACT:R-HSA-4085011 |
| Defective GSS causes Glutathione synthetase deficiency (GSS deficiency) REACT:R-HSA-5579006 |
| Defective HK1 causes hexokinase deficiency (HK deficiency) REACT:R-HSA-5619056 |
| Defective HLCS causes multiple carboxylase deficiency REACT:R-HSA-3371599 |
| Defective LARGE causes MDDGA6 and MDDGB6 REACT:R-HSA-5083627 |
| Defective LFNG causes SCDO3 REACT:R-HSA-5083630 |
| Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF REACT:R-HSA-3359458 |
| Defective MAN1B1 causes MRT15 REACT:R-HSA-4793950 |
| Defective MAOA causes Brunner syndrome (BRUNS) REACT:R-HSA-5579012 |
| Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) REACT:R-HSA-5579024 |
| Defective MGAT2 causes MGAT2-CDG (CDG-2a) REACT:R-HSA-4793952 |
| Defective MMAA causes methylmalonic aciduria type cblA REACT:R-HSA-3359475 |
| Defective MMAB causes methylmalonic aciduria type cblB REACT:R-HSA-3359471 |
| Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC REACT:R-HSA-3359474 |
| Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD REACT:R-HSA-3359473 |
| Defective MOGS causes MOGS-CDG (CDG-2b) REACT:R-HSA-4793954 |
| Defective MPDU1 causes MPDU1-CDG (CDG-1f) REACT:R-HSA-4687000 |
| Defective MPI causes MPI-CDG (CDG-1b) REACT:R-HSA-4043916 |
| Defective MTR causes methylmalonic aciduria and homocystinuria type cblG REACT:R-HSA-3359469 |
| Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE REACT:R-HSA-3359467 |
| Defective MUT causes methylmalonic aciduria mut type REACT:R-HSA-3359478 |
| Defective NEU1 causes sialidosis REACT:R-HSA-4341670 |
| Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) REACT:R-HSA-5578998 |
| Defective PAPSS2 causes SEMD-PA REACT:R-HSA-3560796 |
| Defective PGM1 causes PGM1-CDG (CDG1t) REACT:R-HSA-5609974 |
| Defective PMM2 causes PMM2-CDG (CDG-1a) REACT:R-HSA-4043911 |
| Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 REACT:R-HSA-5083628 |
| Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 REACT:R-HSA-5083633 |
| Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2 REACT:R-HSA-5083629 |
| Defective pro-SFTPB causes pulmonary surfactant metabolism dysfunction 1 (SMDP1) and respiratory distress syndrome (RDS) REACT:R-HSA-5688031 |
| Defective pro-SFTPC causes pulmonary surfactant metabolism dysfunction 2 (SMDP2) and respiratory distress syndrome (RDS) REACT:R-HSA-5688354 |
| Defective RFT1 causes RFT1-CDG (CDG-1n) REACT:R-HSA-4570571 |
| Defective RHAG causes regulator type Rh-null hemolytic anemia (RHN) REACT:R-HSA-5619042 |
| Defective SFTPA2 causes idiopathic pulmonary fibrosis (IPF) REACT:R-HSA-5687868 |
| Defective SLC11A2 causes hypochromic microcytic anemia, with iron overload 1 (AHMIO1) REACT:R-HSA-5619048 |
| Defective SLC12A1 causes Bartter syndrome 1 (BS1) REACT:R-HSA-5619104 |
| Defective SLC12A3 causes Gitelman syndrome (GS) REACT:R-HSA-5619087 |
| Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) REACT:R-HSA-5619039 |
| Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT) REACT:R-HSA-5619070 |
| Defective SLC17A5 causes Salla disease (SD) and ISSD REACT:R-HSA-5619035 |
| Defective SLC17A8 causes autosomal dominant deafness 25 (DFNA25) REACT:R-HSA-5619076 |
| Defective SLC1A1 is implicated in schizophrenia 18 (SCZD18) and dicarboxylic aminoaciduria (DCBXA) REACT:R-HSA-5619067 |
| Defective SLC1A3 causes episodic ataxia 6 (EA6) REACT:R-HSA-5619062 |
| Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) REACT:R-HSA-5619111 |
| Defective SLC22A12 causes renal hypouricemia 1 (RHUC1) REACT:R-HSA-5619071 |
| Defective SLC22A18 causes lung cancer (LNCR) and embryonal rhabdomyosarcoma 1 (RMSE1) REACT:R-HSA-5619066 |
| Defective SLC22A5 causes systemic primary carnitine deficiency (CDSP) REACT:R-HSA-5619053 |
| Defective SLC24A1 causes congenital stationary night blindness 1D (CSNB1D) REACT:R-HSA-5619077 |
| Defective SLC24A4 causes hypomineralized amelogenesis imperfecta (AI) REACT:R-HSA-5619055 |
| Defective SLC24A5 causes oculocutaneous albinism 6 (OCA6) REACT:R-HSA-5619036 |
| Defective SLC26A2 causes chondrodysplasias REACT:R-HSA-3560792 |
| Defective SLC26A3 causes congenital secretory chloride diarrhea 1 (DIAR1) REACT:R-HSA-5619085 |
| Defective SLC26A4 causes Pendred syndrome (PDS) REACT:R-HSA-5619046 |
| Defective SLC27A4 causes ichthyosis prematurity syndrome (IPS) REACT:R-HSA-5619108 |
| Defective SLC29A3 causes histiocytosis-lymphadenopathy plus syndrome (HLAS) REACT:R-HSA-5619063 |
| Defective SLC2A10 causes arterial tortuosity syndrome (ATS) REACT:R-HSA-5619068 |
| Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1) REACT:R-HSA-5619043 |
| Defective SLC2A2 causes Fanconi-Bickel syndrome (FBS) REACT:R-HSA-5619098 |
| Defective SLC2A9 causes hypouricemia renal 2 (RHUC2) REACT:R-HSA-5619047 |
| Defective SLC33A1 causes spastic paraplegia 42 (SPG42) REACT:R-HSA-5619061 |
| Defective SLC34A1 causes hypophosphatemic nephrolithiasis/osteoporosis 1 (NPHLOP1) REACT:R-HSA-5619040 |
| Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM) REACT:R-HSA-5619045 |
| Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM) REACT:R-HSA-5687583 |
| Defective SLC34A3 causes Hereditary hypophosphatemic rickets with hypercalciuria (HHRH) REACT:R-HSA-5619097 |
| Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F) REACT:R-HSA-5619037 |
| Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F) REACT:R-HSA-5663020 |
| Defective SLC35A2 causes congenital disorder of glycosylation 2M (CDG2M) REACT:R-HSA-5619072 |
| Defective SLC35A3 causes arthrogryposis, mental retardation, and seizures (AMRS) REACT:R-HSA-5619083 |
| Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C) REACT:R-HSA-5619078 |
| Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) REACT:R-HSA-5579020 |
| Defective SLC36A2 causes iminoglycinuria (IG) and hyperglycinuria (HG) REACT:R-HSA-5619041 |
| Defective SLC39A4 causes acrodermatitis enteropathica, zinc-deficiency type (AEZ) REACT:R-HSA-5619088 |
| Defective SLC3A1 causes cystinuria (CSNU) REACT:R-HSA-5619113 |
| Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) REACT:R-HSA-5655799 |
| Defective SLC40A1 causes hemochromatosis 4 (HFE4) (macrophages) REACT:R-HSA-5619049 |
| Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) REACT:R-HSA-5619050 |
| Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) REACT:R-HSA-5619054 |
| Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) REACT:R-HSA-5656364 |
| Defective SLC5A2 causes renal glucosuria (GLYS1) REACT:R-HSA-5658208 |
| Defective SLC5A5 causes thyroid dyshormonogenesis 1 (TDH1) REACT:R-HSA-5619096 |
| Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A) REACT:R-HSA-5619114 |
| Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A) REACT:R-HSA-5658471 |
| Defective SLC6A18 may confer susceptibility to iminoglycinuria and/or hyperglycinuria REACT:R-HSA-5619079 |
| Defective SLC6A18 may confer susceptibility to iminoglycinuria and/or hyperglycinuria REACT:R-HSA-5659729 |
| Defective SLC6A19 causes Hartnup disorder (HND) REACT:R-HSA-5619044 |
| Defective SLC6A19 causes Hartnup disorder (HND) REACT:R-HSA-5659735 |
| Defective SLC6A2 causes orthostatic intolerance (OI) REACT:R-HSA-5619109 |
| Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) REACT:R-HSA-5619081 |
| Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) REACT:R-HSA-5660724 |
| Defective SLC6A5 causes hyperekplexia 3 (HKPX3) REACT:R-HSA-5619089 |
| Defective SLC7A7 causes lysinuric protein intolerance (LPI) REACT:R-HSA-5660862 |
| Defective SLC7A9 causes cystinuria (CSNU) REACT:R-HSA-5660883 |
| Defective SLC9A6 causes X-linked, syndromic mental retardation,, Christianson type (MRXSCH) REACT:R-HSA-5619092 |
| Defective SLC9A9 causes autism 16 (AUTS16) REACT:R-HSA-5619052 |
| Defective SLCO1B1 causes hyperbilirubinemia, Rotor type (HBLRR) REACT:R-HSA-5619110 |
| Defective SLCO1B1 causes hyperbilirubinemia, Rotor type (HBLRR) REACT:R-HSA-5661182 |
| Defective SLCO1B3 causes hyperbilirubinemia, Rotor type (HBLRR) REACT:R-HSA-5619058 |
| Defective SLCO2A1 causes primary, autosomal recessive hypertrophic osteoarthropathy 2 (PHOAR2) REACT:R-HSA-5619095 |
| Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ REACT:R-HSA-4755579 |
| Defective ST3GAL3 causes MCT12 and EIEE15 REACT:R-HSA-3656243 |
| Defective TBXAS1 causes Ghosal hematodiaphyseal dysplasia (GHDD) REACT:R-HSA-5579032 |
| Defective TCN2 causes hereditary megaloblastic anemia REACT:R-HSA-3359454 |
| Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) REACT:R-HSA-5578995 |
| Defective TRP may confer susceptibility towards thyroid papillary carcinoma (TPC) REACT:R-HSA-5619107 |
| Defective UGT1A1 causes hyperbilirubinemia REACT:R-HSA-5579002 |
| Defective UGT1A4 causes hyperbilirubinemia REACT:R-HSA-5579016 |
| Defects in biotin (Btn) metabolism REACT:R-HSA-3323169 |
| Defects in cobalamin (B12) metabolism REACT:R-HSA-3296469 |
| Defects in vitamin and cofactor metabolism REACT:R-HSA-3296482 |
| Defensins REACT:R-HSA-1461973 |
| Degradation of AXIN REACT:R-HSA-4641257 |
| Degradation of beta-catenin by the destruction complex REACT:R-HSA-195253 |
| Degradation of cysteine and homocysteine REACT:R-HSA-1614558 |
| Degradation of DVL REACT:R-HSA-4641258 |
| Degradation of GABA REACT:R-HSA-916853 |
| Degradation of GLI1 by the proteasome REACT:R-HSA-5610780 |
| Degradation of GLI2 by the proteasome REACT:R-HSA-5610783 |
| Degradation of the extracellular matrix REACT:R-HSA-1474228 |
| Deletions in the AMER1 gene destabilize the destruction complex REACT:R-HSA-5467343 |
| Deletions in the AXIN genes in hepatocellular carcinoma result in elevated WNT signaling REACT:R-HSA-5467345 |
| Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels REACT:R-HSA-112308 |
| Depolymerisation of the Nuclear Lamina REACT:R-HSA-4419969 |
| Deposition of new CENPA-containing nucleosomes at the centromere REACT:R-HSA-606279 |
| Depurination REACT:R-HSA-73927 |
| Depyrimidination REACT:R-HSA-73928 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models REACT:R-HSA-8862803 |
| Dermatan sulfate biosynthesis REACT:R-HSA-2022923 |
| Dermatan sulfate degradation KEGG:hsa_M00076 |
| Detoxification of Reactive Oxygen Species REACT:R-HSA-3299685 |
| Deubiquitination REACT:R-HSA-5688426 |
| Developmental Biology REACT:R-HSA-1266738 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production REACT:R-HSA-3134963 |
| D-Glutamine and D-glutamate metabolism KEGG:hsa00471 |
| Digestion of dietary carbohydrate REACT:R-HSA-189085 |
| Digestion of dietary lipid REACT:R-HSA-192456 |
| Dilated cardiomyopathy KEGG:hsa05414 |
| Dimerization of procaspase-8 REACT:R-HSA-69416 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane REACT:R-HSA-4641262 |
| Disease REACT:R-HSA-1643685 |
| Diseases associated with glycosaminoglycan metabolism REACT:R-HSA-3560782 |
| Diseases associated with glycosylation precursor biosynthesis REACT:R-HSA-5609975 |
| Diseases associated with N-glycosylation of proteins REACT:R-HSA-3781860 |
| Diseases associated with O-glycosylation of proteins REACT:R-HSA-3906995 |
| Diseases associated with surfactant metabolism REACT:R-HSA-5687613 |
| Diseases associated with the TLR signaling cascade REACT:R-HSA-5602358 |
| Diseases associated with visual transduction REACT:R-HSA-2474795 |
| Diseases of carbohydrate metabolism REACT:R-HSA-5663084 |
| Diseases of glycosylation REACT:R-HSA-3781865 |
| Diseases of Immune System REACT:R-HSA-5260271 |
| Diseases of metabolism REACT:R-HSA-5668914 |
| Diseases of signal transduction REACT:R-HSA-5663202 |
| Disinhibition of SNARE formation REACT:R-HSA-114516 |
| Disorders of transmembrane transporters REACT:R-HSA-5619115 |
| Displacement of DNA glycosylase by APEX1 REACT:R-HSA-110357 |
| Dissolution of Fibrin Clot REACT:R-HSA-75205 |
| DNA Damage Bypass REACT:R-HSA-73893 |
| DNA damage-induced cell cycle checkpoints KEGG:hsa_M00691 |
| DNA Damage Recognition in GG-NER REACT:R-HSA-5696394 |
| DNA Damage Reversal REACT:R-HSA-73942 |
| DNA Damage/Telomere Stress Induced Senescence REACT:R-HSA-2559586 |
| DNA Double-Strand Break Repair REACT:R-HSA-5693532 |
| DNA Double Strand Break Response REACT:R-HSA-5693606 |
| DNA methylation REACT:R-HSA-5334118 |
| DNA-PK complex KEGG:hsa_M00297 |
| DNA polymerase alpha / primase complex KEGG:hsa_M00261 |
| DNA polymerase delta complex KEGG:hsa_M00262 |
| DNA polymerase epsilon complex KEGG:hsa_M00263 |
| DNA polymerase gamma complex KEGG:hsa_M00294 |
| DNA polymerase zeta complex KEGG:hsa_M00293 |
| DNA Repair REACT:R-HSA-73894 |
| DNA replication KEGG:hsa03030 |
| DNA Replication REACT:R-HSA-69306 |
| DNA replication initiation REACT:R-HSA-68952 |
| DNA Replication Pre-Initiation REACT:R-HSA-69002 |
| DNA strand elongation REACT:R-HSA-69190 |
| Dopamine clearance from the synaptic cleft REACT:R-HSA-379401 |
| Dopamine Neurotransmitter Release Cycle REACT:R-HSA-212676 |
| Dopamine receptors REACT:R-HSA-390651 |
| Dopaminergic synapse KEGG:hsa04728 |
| Dorso-ventral axis formation KEGG:hsa04320 |
| Downregulation of ERBB2:ERBB3 signaling REACT:R-HSA-1358803 |
| Downregulation of ERBB2 signaling REACT:R-HSA-8863795 |
| Downregulation of ERBB4 signaling REACT:R-HSA-1253288 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity REACT:R-HSA-2173795 |
| Downregulation of TGF-beta receptor signaling REACT:R-HSA-2173788 |
| Downstream signaling events of B Cell Receptor (BCR) REACT:R-HSA-1168372 |
| Downstream signaling of activated FGFR1 REACT:R-HSA-5654687 |
| Downstream signaling of activated FGFR2 REACT:R-HSA-5654696 |
| Downstream signaling of activated FGFR3 REACT:R-HSA-5654708 |
| Downstream signaling of activated FGFR4 REACT:R-HSA-5654716 |
| Downstream signal transduction REACT:R-HSA-186763 |
| Downstream TCR signaling REACT:R-HSA-202424 |
| Drug metabolism - cytochrome P450 KEGG:hsa00982 |
| Drug metabolism - other enzymes KEGG:hsa00983 |
| DSCAM interactions REACT:R-HSA-376172 |
| Dual Incision in GG-NER REACT:R-HSA-5696400 |
| Dual incision in TC-NER REACT:R-HSA-6782135 |
| E2F-enabled inhibition of pre-replication complex formation REACT:R-HSA-113507 |
| E2F mediated regulation of DNA replication REACT:R-HSA-113510 |
| E3 ubiquitin ligases ubiquitinate target proteins REACT:R-HSA-8866654 |
| Early Phase of HIV Life Cycle REACT:R-HSA-162594 |
| ECM proteoglycans REACT:R-HSA-3000178 |
| ECM-receptor interaction KEGG:hsa04512 |
| ECS complex KEGG:hsa_M00388 |
| ECV complex KEGG:hsa_M00383 |
| Effects of PIP2 hydrolysis REACT:R-HSA-114508 |
| EGFR downregulation REACT:R-HSA-182971 |
| EGFR interacts with phospholipase C-gamma REACT:R-HSA-212718 |
| EGFR Transactivation by Gastrin REACT:R-HSA-2179392 |
| EGFR tyrosine kinase inhibitor resistance KEGG:hsa01521 |
| Eicosanoid ligand-binding receptors REACT:R-HSA-391903 |
| Eicosanoids REACT:R-HSA-211979 |
| eIF4F complex KEGG:hsa_M00428 |
| Elastic fibre formation REACT:R-HSA-1566948 |
| Electric Transmission Across Gap Junctions REACT:R-HSA-112303 |
| Electron transport from NADPH to Ferredoxin REACT:R-HSA-2395516 |
| Elevation of cytosolic Ca2+ levels REACT:R-HSA-139853 |
| Endocrine and other factor-regulated calcium reabsorption KEGG:hsa04961 |
| Endocrine resistance KEGG:hsa01522 |
| Endocytosis KEGG:hsa04144 |
| Endogenous sterols REACT:R-HSA-211976 |
| Endometrial cancer KEGG:hsa05213 |
| Endosomal Sorting Complex Required For Transport (ESCRT) REACT:R-HSA-917729 |
| Endosomal/Vacuolar pathway REACT:R-HSA-1236977 |
| Energy dependent regulation of mTOR by LKB1-AMPK REACT:R-HSA-380972 |
| eNOS activation REACT:R-HSA-203615 |
| eNOS activation and regulation REACT:R-HSA-203765 |
| Entry of Influenza Virion into Host Cell via Endocytosis REACT:R-HSA-168275 |
| Enzymatic degradation of dopamine by COMT REACT:R-HSA-379397 |
| Enzymatic degradation of Dopamine by monoamine oxidase REACT:R-HSA-379398 |
| EPHA-mediated growth cone collapse REACT:R-HSA-3928663 |
| EPHB-mediated forward signaling REACT:R-HSA-3928662 |
| EPH-ephrin mediated repulsion of cells REACT:R-HSA-3928665 |
| EPH-Ephrin signaling REACT:R-HSA-2682334 |
| Ephrin signaling REACT:R-HSA-3928664 |
| Epigenetic regulation of gene expression REACT:R-HSA-212165 |
| Epithelial cell signaling in Helicobacter pylori infection KEGG:hsa05120 |
| Epstein-Barr virus infection KEGG:hsa05169 |
| ERBB2 Activates PTK6 Signaling REACT:R-HSA-8847993 |
| ERBB2 Regulates Cell Motility REACT:R-HSA-6785631 |
| ErbB signaling pathway KEGG:hsa04012 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression REACT:R-HSA-427389 |
| ERK/MAPK targets REACT:R-HSA-198753 |
| ERKs are inactivated REACT:R-HSA-202670 |
| ER-Phagosome pathway REACT:R-HSA-1236974 |
| ER Quality Control Compartment (ERQC) REACT:R-HSA-901032 |
| ER to Golgi Anterograde Transport REACT:R-HSA-199977 |
| Erythrocytes take up carbon dioxide and release oxygen REACT:R-HSA-1237044 |
| Erythrocytes take up oxygen and release carbon dioxide REACT:R-HSA-1247673 |
| ESCRT-0 complex KEGG:hsa_M00408 |
| ESCRT-I complex KEGG:hsa_M00409 |
| ESCRT-II complex KEGG:hsa_M00410 |
| ESCRT-III complex KEGG:hsa_M00412 |
| Essential fructosuria REACT:R-HSA-5657562 |
| Essential pentosuria REACT:R-HSA-5662853 |
| Establishment of Sister Chromatid Cohesion REACT:R-HSA-2468052 |
| Estrogen biosynthesis REACT:R-HSA-193144 |
| Estrogen signaling pathway KEGG:hsa04915 |
| Ethanol oxidation REACT:R-HSA-71384 |
| Ether lipid metabolism KEGG:hsa00565 |
| Eukaryotic Translation Elongation REACT:R-HSA-156842 |
| Eukaryotic Translation Initiation REACT:R-HSA-72613 |
| Eukaryotic Translation Termination REACT:R-HSA-72764 |
| Exon junction complex (EJC) KEGG:hsa_M00430 |
| Exosome, archaea KEGG:hsa_M00390 |
| Exosome, eukaryotes KEGG:hsa_M00391 |
| Export of Viral Ribonucleoproteins from Nucleus REACT:R-HSA-168274 |
| Extension of Telomeres REACT:R-HSA-180786 |
| Extracellular matrix organization REACT:R-HSA-1474244 |
| Extrinsic Pathway of Fibrin Clot Formation REACT:R-HSA-140834 |
| Facilitative Na+-independent glucose transporters REACT:R-HSA-428790 |
| FA core complex KEGG:hsa_M00413 |
| Factors involved in megakaryocyte development and platelet production REACT:R-HSA-983231 |
| Fanconi anemia pathway KEGG:hsa03460 |
| Fanconi Anemia Pathway REACT:R-HSA-6783310 |
| FasL/ CD95L signaling REACT:R-HSA-75157 |
| Fat digestion and absorption KEGG:hsa04975 |
| Fatty acid biosynthesis KEGG:hsa00061 |
| Fatty acid biosynthesis, elongation KEGG:hsa_M00083 |
| Fatty acid biosynthesis, elongation, endoplasmic reticulum KEGG:hsa_M00415 |
| Fatty acid biosynthesis, elongation, mitochondria KEGG:hsa_M00085 |
| Fatty acid biosynthesis, initiation KEGG:hsa_M00082 |
| Fatty acid degradation KEGG:hsa00071 |
| Fatty acid elongation KEGG:hsa00062 |
| Fatty acid metabolism KEGG:hsa01212 |
| Fatty acids REACT:R-HSA-211935 |
| Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion REACT:R-HSA-434316 |
| Fatty acid, triacylglycerol, and ketone body metabolism REACT:R-HSA-535734 |
| Fatty Acyl-CoA Biosynthesis REACT:R-HSA-75105 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis REACT:R-HSA-8854050 |
| FBXW7 Mutants and NOTCH1 in Cancer REACT:R-HSA-2644605 |
| Fc epsilon receptor (FCERI) signaling REACT:R-HSA-2454202 |
| Fc epsilon RI signaling pathway KEGG:hsa04664 |
| FCERI mediated Ca+2 mobilization REACT:R-HSA-2871809 |
| FCERI mediated MAPK activation REACT:R-HSA-2871796 |
| FCERI mediated NF-kB activation REACT:R-HSA-2871837 |
| Fcgamma receptor (FCGR) dependent phagocytosis REACT:R-HSA-2029480 |
| Fc gamma R-mediated phagocytosis KEGG:hsa04666 |
| FCGR activation REACT:R-HSA-2029481 |
| Ferroptosis KEGG:hsa04216 |
| Fertilization REACT:R-HSA-1187000 |
| FGFR1b ligand binding and activation REACT:R-HSA-190370 |
| FGFR1c and Klotho ligand binding and activation REACT:R-HSA-190374 |
| FGFR1c ligand binding and activation REACT:R-HSA-190373 |
| FGFR1 ligand binding and activation REACT:R-HSA-190242 |
| FGFR1 mutant receptor activation REACT:R-HSA-1839124 |
| FGFR2 alternative splicing REACT:R-HSA-6803529 |
| FGFR2b ligand binding and activation REACT:R-HSA-190377 |
| FGFR2c ligand binding and activation REACT:R-HSA-190375 |
| FGFR2 ligand binding and activation REACT:R-HSA-190241 |
| FGFR2 mutant receptor activation REACT:R-HSA-1839126 |
| FGFR3b ligand binding and activation REACT:R-HSA-190371 |
| FGFR3c ligand binding and activation REACT:R-HSA-190372 |
| FGFR3 ligand binding and activation REACT:R-HSA-190239 |
| FGFR3 mutant receptor activation REACT:R-HSA-2033514 |
| FGFR4 ligand binding and activation REACT:R-HSA-190322 |
| FGFR4 mutant receptor activation REACT:R-HSA-1839128 |
| FGFRL1 modulation of FGFR1 signaling REACT:R-HSA-5658623 |
| Fibronectin matrix formation REACT:R-HSA-1566977 |
| Ficolins bind to repetitive carbohydrate structures on the target cell surface REACT:R-HSA-2855086 |
| Fluid shear stress and atherosclerosis KEGG:hsa05418 |
| FMO oxidises nucleophiles REACT:R-HSA-217271 |
| Focal adhesion KEGG:hsa04510 |
| Folate biosynthesis KEGG:hsa00790 |
| Folding of actin by CCT/TriC REACT:R-HSA-390450 |
| Formation of annular gap junctions REACT:R-HSA-196025 |
| Formation of a pool of free 40S subunits REACT:R-HSA-72689 |
| Formation of apoptosome REACT:R-HSA-111458 |
| Formation of ATP by chemiosmotic coupling REACT:R-HSA-163210 |
| Formation of editosomes by ADAR proteins REACT:R-HSA-77042 |
| Formation of Fibrin Clot (Clotting Cascade) REACT:R-HSA-140877 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat REACT:R-HSA-167200 |
| Formation of HIV elongation complex in the absence of HIV Tat REACT:R-HSA-167152 |
| Formation of Incision Complex in GG-NER REACT:R-HSA-5696395 |
| Formation of RNA Pol II elongation complex REACT:R-HSA-112382 |
| Formation of selenosugars for excretion REACT:R-HSA-2408499 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) REACT:R-HSA-2559584 |
| Formation of TC-NER Pre-Incision Complex REACT:R-HSA-6781823 |
| Formation of the active cofactor, UDP-glucuronate REACT:R-HSA-173599 |
| Formation of the beta-catenin:TCF transactivating complex REACT:R-HSA-201722 |
| Formation of the cornified envelope REACT:R-HSA-6809371 |
| Formation of the Early Elongation Complex REACT:R-HSA-113418 |
| Formation of the Editosome REACT:R-HSA-75094 |
| Formation of the HIV-1 Early Elongation Complex REACT:R-HSA-167158 |
| Formation of the ternary complex, and subsequently, the 43S complex REACT:R-HSA-72695 |
| Formation of tubulin folding intermediates by CCT/TriC REACT:R-HSA-389960 |
| Formyl peptide receptors bind formyl peptides and many other ligands REACT:R-HSA-444473 |
| FoxO signaling pathway KEGG:hsa04068 |
| Free fatty acid receptors REACT:R-HSA-444209 |
| Free fatty acids regulate insulin secretion REACT:R-HSA-400451 |
| Frs2-mediated activation REACT:R-HSA-170968 |
| FRS-mediated FGFR1 signaling REACT:R-HSA-5654693 |
| FRS-mediated FGFR2 signaling REACT:R-HSA-5654700 |
| FRS-mediated FGFR3 signaling REACT:R-HSA-5654706 |
| FRS-mediated FGFR4 signaling REACT:R-HSA-5654712 |
| Fructose and mannose metabolism KEGG:hsa00051 |
| Fructose biosynthesis REACT:R-HSA-5652227 |
| Fructose catabolism REACT:R-HSA-70350 |
| Fructose metabolism REACT:R-HSA-5652084 |
| F-type ATPase, eukaryotes KEGG:hsa_M00158 |
| Fusion and Uncoating of the Influenza Virion REACT:R-HSA-168270 |
| Fusion of the Influenza Virion to the Host Cell Endosome REACT:R-HSA-168288 |
| G0 and Early G1 REACT:R-HSA-1538133 |
| G1 Phase REACT:R-HSA-69236 |
| G1/S DNA Damage Checkpoints REACT:R-HSA-69615 |
| G1/S-Specific Transcription REACT:R-HSA-69205 |
| G1/S Transition REACT:R-HSA-69206 |
| G2/M Checkpoints REACT:R-HSA-69481 |
| G2/M DNA damage checkpoint REACT:R-HSA-69473 |
| G2/M DNA replication checkpoint REACT:R-HSA-69478 |
| G2/M Transition REACT:R-HSA-69275 |
| G2 Phase REACT:R-HSA-68911 |
| GAB1 signalosome REACT:R-HSA-180292 |
| GABA A receptor activation REACT:R-HSA-977441 |
| GABA A (rho) receptor activation REACT:R-HSA-977442 |
| GABA biosynthesis, eukaryotes, putrescine => GABA KEGG:hsa_M00135 |
| GABA B receptor activation REACT:R-HSA-977444 |
| GABAergic synapse KEGG:hsa04727 |
| GABA (gamma-Aminobutyrate) shunt KEGG:hsa_M00027 |
| GABA receptor activation REACT:R-HSA-977443 |
| GABA synthesis REACT:R-HSA-888568 |
| GABA synthesis, release, reuptake and degradation REACT:R-HSA-888590 |
| Galactose catabolism REACT:R-HSA-70370 |
| Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P KEGG:hsa_M00632 |
| Galactose metabolism KEGG:hsa00052 |
| G alpha (12/13) signalling events REACT:R-HSA-416482 |
| G alpha (i) signalling events REACT:R-HSA-418594 |
| G alpha (q) signalling events REACT:R-HSA-416476 |
| G alpha (s) signalling events REACT:R-HSA-418555 |
| G alpha (z) signalling events REACT:R-HSA-418597 |
| Gamma carboxylation, hypusine formation and arylsulfatase activation REACT:R-HSA-163841 |
| Gamma-carboxylation of protein precursors REACT:R-HSA-159740 |
| Gamma-carboxylation, transport, and amino-terminal cleavage of proteins REACT:R-HSA-159854 |
| Gap-filling DNA repair synthesis and ligation in GG-NER REACT:R-HSA-5696397 |
| Gap-filling DNA repair synthesis and ligation in TC-NER REACT:R-HSA-6782210 |
| Gap junction KEGG:hsa04540 |
| Gap junction assembly REACT:R-HSA-190861 |
| Gap junction degradation REACT:R-HSA-190873 |
| Gap junction trafficking REACT:R-HSA-190828 |
| Gap junction trafficking and regulation REACT:R-HSA-157858 |
| Gastric acid secretion KEGG:hsa04971 |
| Gastrin-CREB signalling pathway via PKC and MAPK REACT:R-HSA-881907 |
| G beta:gamma signalling through PI3Kgamma REACT:R-HSA-392451 |
| G beta:gamma signalling through PLC beta REACT:R-HSA-418217 |
| GDP-fucose biosynthesis REACT:R-HSA-6787639 |
| Gene Expression REACT:R-HSA-74160 |
| Generation of second messenger molecules REACT:R-HSA-202433 |
| Generic Transcription Pathway REACT:R-HSA-212436 |
| Gene Silencing by RNA REACT:R-HSA-211000 |
| GINS complex KEGG:hsa_M00286 |
| GLI3 is processed to GLI3R by the proteasome REACT:R-HSA-5610785 |
| Glioma KEGG:hsa05214 |
| GLI proteins bind promoters of Hh responsive genes to promote transcription REACT:R-HSA-5635851 |
| Global Genome Nucleotide Excision Repair (GG-NER) REACT:R-HSA-5696399 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion REACT:R-HSA-381676 |
| Glucagon signaling in metabolic regulation REACT:R-HSA-163359 |
| Glucagon signaling pathway KEGG:hsa04922 |
| Glucagon-type ligand receptors REACT:R-HSA-420092 |
| Glucocorticoid biosynthesis REACT:R-HSA-194002 |
| Gluconeogenesis REACT:R-HSA-70263 |
| Gluconeogenesis, oxaloacetate => fructose-6P KEGG:hsa_M00003 |
| Glucose metabolism REACT:R-HSA-70326 |
| Glucose transport REACT:R-HSA-70153 |
| Glucuronate pathway (uronate pathway) KEGG:hsa_M00014 |
| Glucuronidation REACT:R-HSA-156588 |
| Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity REACT:R-HSA-399721 |
| Glutamate Neurotransmitter Release Cycle REACT:R-HSA-210500 |
| Glutamatergic synapse KEGG:hsa04724 |
| Glutathione biosynthesis, glutamate => glutathione KEGG:hsa_M00118 |
| Glutathione conjugation REACT:R-HSA-156590 |
| Glutathione metabolism KEGG:hsa00480 |
| Glutathione synthesis and recycling REACT:R-HSA-174403 |
| Glycerolipid metabolism KEGG:hsa00561 |
| Glycerophospholipid biosynthesis REACT:R-HSA-1483206 |
| Glycerophospholipid catabolism REACT:R-HSA-6814848 |
| Glycerophospholipid metabolism KEGG:hsa00564 |
| Glycine degradation REACT:R-HSA-6783984 |
| Glycine, serine and threonine metabolism KEGG:hsa00260 |
| Glycogen breakdown (glycogenolysis) REACT:R-HSA-70221 |
| Glycogen storage diseases REACT:R-HSA-3229121 |
| Glycogen storage disease type 0 (liver GYS2) REACT:R-HSA-3858516 |
| Glycogen storage disease type 0 (muscle GYS1) REACT:R-HSA-3828062 |
| Glycogen storage disease type Ia (G6PC) REACT:R-HSA-3274531 |
| Glycogen storage disease type Ib (SLC37A4) REACT:R-HSA-3229133 |
| Glycogen storage disease type II (GAA) REACT:R-HSA-5357609 |
| Glycogen storage disease type IV (GBE1) REACT:R-HSA-3878781 |
| Glycogen storage disease type XV (GYG1) REACT:R-HSA-3814836 |
| Glycogen synthesis REACT:R-HSA-3322077 |
| Glycolysis REACT:R-HSA-70171 |
| Glycolysis, core module involving three-carbon compounds KEGG:hsa_M00002 |
| Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate KEGG:hsa_M00001 |
| Glycolysis / Gluconeogenesis KEGG:hsa00010 |
| Glycoprotein hormones REACT:R-HSA-209822 |
| Glycosaminoglycan biosynthesis, chondroitin sulfate backbone KEGG:hsa_M00058 |
| Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate KEGG:hsa00532 |
| Glycosaminoglycan biosynthesis, heparan sulfate backbone KEGG:hsa_M00059 |
| Glycosaminoglycan biosynthesis - heparan sulfate / heparin KEGG:hsa00534 |
| Glycosaminoglycan biosynthesis - keratan sulfate KEGG:hsa00533 |
| Glycosaminoglycan biosynthesis, linkage tetrasaccharide KEGG:hsa_M00057 |
| Glycosaminoglycan degradation KEGG:hsa00531 |
| Glycosaminoglycan metabolism REACT:R-HSA-1630316 |
| Glycosphingolipid biosynthesis - ganglio series KEGG:hsa00604 |
| Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 KEGG:hsa_M00069 |
| Glycosphingolipid biosynthesis - globo and isoglobo series KEGG:hsa00603 |
| Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer KEGG:hsa_M00068 |
| Glycosphingolipid biosynthesis - lacto and neolacto series KEGG:hsa00601 |
| Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer KEGG:hsa_M00070 |
| Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer KEGG:hsa_M00071 |
| Glycosphingolipid metabolism REACT:R-HSA-1660662 |
| Glycosylphosphatidylinositol (GPI)-anchor biosynthesis KEGG:hsa00563 |
| Glyoxylate and dicarboxylate metabolism KEGG:hsa00630 |
| Glyoxylate metabolism and glycine degradation REACT:R-HSA-389661 |
| GnRH signaling pathway KEGG:hsa04912 |
| Golgi Associated Vesicle Biogenesis REACT:R-HSA-432722 |
| Golgi Cisternae Pericentriolar Stack Reorganization REACT:R-HSA-162658 |
| Golgi-to-ER retrograde transport REACT:R-HSA-8856688 |
| GP1b-IX-V activation signalling REACT:R-HSA-430116 |
| GPCR downstream signaling REACT:R-HSA-388396 |
| GPCR ligand binding REACT:R-HSA-500792 |
| GPI-anchor biosynthesis, core oligosaccharide KEGG:hsa_M00065 |
| G-protein activation REACT:R-HSA-202040 |
| G-protein beta:gamma signalling REACT:R-HSA-397795 |
| G protein gated Potassium channels REACT:R-HSA-1296059 |
| G-protein mediated events REACT:R-HSA-112040 |
| GPVI-mediated activation cascade REACT:R-HSA-114604 |
| Graft-versus-host disease KEGG:hsa05332 |
| GRB2 events in EGFR signaling REACT:R-HSA-179812 |
| GRB2 events in ERBB2 signaling REACT:R-HSA-1963640 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins REACT:R-HSA-354194 |
| GRB7 events in ERBB2 signaling REACT:R-HSA-1306955 |
| Growth hormone receptor signaling REACT:R-HSA-982772 |
| GTP hydrolysis and joining of the 60S ribosomal subunit REACT:R-HSA-72706 |
| Guanine ribonucleotide biosynthesis IMP => GDP,GTP KEGG:hsa_M00050 |
| H/ACA ribonucleoprotein complex KEGG:hsa_M00425 |
| HATs acetylate histones REACT:R-HSA-3214847 |
| HCN channels REACT:R-HSA-1296061 |
| HDACs deacetylate histones REACT:R-HSA-3214815 |
| HDL-mediated lipid transport REACT:R-HSA-194223 |
| HDMs demethylate histones REACT:R-HSA-3214842 |
| HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) REACT:R-HSA-5693567 |
| HDR through Homologous Recombination (HRR) REACT:R-HSA-5685942 |
| HDR through MMEJ (alt-NHEJ) REACT:R-HSA-5685939 |
| HDR through Single Strand Annealing (SSA) REACT:R-HSA-5685938 |
| Hedgehog ligand biogenesis REACT:R-HSA-5358346 |
| Hedgehog 'off' state REACT:R-HSA-5610787 |
| Hedgehog 'on' state REACT:R-HSA-5632684 |
| Hedgehog signaling KEGG:hsa_M00678 |
| Hedgehog signaling pathway KEGG:hsa04340 |
| Hematopoietic cell lineage KEGG:hsa04640 |
| Heme biosynthesis REACT:R-HSA-189451 |
| Heme degradation REACT:R-HSA-189483 |
| Hemostasis REACT:R-HSA-109582 |
| Heparan sulfate degradation KEGG:hsa_M00078 |
| Heparan sulfate/heparin (HS-GAG) metabolism REACT:R-HSA-1638091 |
| Hepatitis B KEGG:hsa05161 |
| Hepatitis C KEGG:hsa05160 |
| Hereditary fructose intolerance REACT:R-HSA-5657560 |
| Herpes simplex infection KEGG:hsa05168 |
| Hexose transport REACT:R-HSA-189200 |
| HHAT G278V abrogates palmitoylation of Hh-Np REACT:R-HSA-5658034 |
| Hh mutants abrogate ligand secretion REACT:R-HSA-5387390 |
| Hh mutants that don't undergo autocatalytic processing are degraded by ERAD REACT:R-HSA-5362768 |
| HIF-1 signaling pathway KEGG:hsa04066 |
| Highly calcium permeable nicotinic acetylcholine receptors REACT:R-HSA-629597 |
| Highly calcium permeable postsynaptic nicotinic acetylcholine receptors REACT:R-HSA-629594 |
| Highly sodium permeable acetylcholine nicotinic receptors REACT:R-HSA-629587 |
| Hippo signaling KEGG:hsa_M00683 |
| Hippo signaling pathway KEGG:hsa04390 |
| Hippo signaling pathway -multiple species KEGG:hsa04392 |
| Histamine receptors REACT:R-HSA-390650 |
| Histidine catabolism REACT:R-HSA-70921 |
| Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism REACT:R-HSA-6788656 |
| Histidine metabolism KEGG:hsa00340 |
| HIV elongation arrest and recovery REACT:R-HSA-167287 |
| HIV Infection REACT:R-HSA-162906 |
| HIV Life Cycle REACT:R-HSA-162587 |
| HIV Transcription Elongation REACT:R-HSA-167169 |
| HIV Transcription Initiation REACT:R-HSA-167161 |
| Holo-TFIIH complex KEGG:hsa_M00290 |
| Homologous DNA Pairing and Strand Exchange REACT:R-HSA-5693579 |
| Homologous recombination KEGG:hsa03440 |
| Homology Directed Repair REACT:R-HSA-5693538 |
| Hormone ligand-binding receptors REACT:R-HSA-375281 |
| Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis REACT:R-HSA-163560 |
| Host Interactions of HIV factors REACT:R-HSA-162909 |
| Host Interactions with Influenza Factors REACT:R-HSA-168253 |
| HRD1/SEL1 ERAD complex KEGG:hsa_M00403 |
| HSF1 activation REACT:R-HSA-3371511 |
| HSF1-dependent transactivation REACT:R-HSA-3371571 |
| HS-GAG biosynthesis REACT:R-HSA-2022928 |
| HS-GAG degradation REACT:R-HSA-2024096 |
| HTLV-I infection KEGG:hsa05166 |
| Huntington's disease KEGG:hsa05016 |
| HuR (ELAVL1) binds and stabilizes mRNA REACT:R-HSA-450520 |
| Hyaluronan biosynthesis and export REACT:R-HSA-2142850 |
| Hyaluronan metabolism REACT:R-HSA-2142845 |
| Hyaluronan uptake and degradation REACT:R-HSA-2160916 |
| Hydrolysis of LPC REACT:R-HSA-1483115 |
| Hydrolysis of LPE REACT:R-HSA-1483152 |
| Hydroxycarboxylic acid-binding receptors REACT:R-HSA-3296197 |
| Hypertrophic cardiomyopathy (HCM) KEGG:hsa05410 |
| Hypusine synthesis from eIF5A-lysine REACT:R-HSA-204626 |
| IGF1R signaling cascade REACT:R-HSA-2428924 |
| IkBA variant leads to EDA-ID REACT:R-HSA-5603029 |
| IKBKB deficiency causes SCID REACT:R-HSA-5602636 |
| IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) REACT:R-HSA-5603027 |
| IKK complex recruitment mediated by RIP1 REACT:R-HSA-937041 |
| IL-17 signaling pathway KEGG:hsa04657 |
| IL-6-type cytokine receptor ligand interactions REACT:R-HSA-6788467 |
| Immune System REACT:R-HSA-168256 |
| Immunoproteasome KEGG:hsa_M00337 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell REACT:R-HSA-198933 |
| Import of palmitoyl-CoA into the mitochondrial matrix REACT:R-HSA-200425 |
| Inactivation of APC/C via direct inhibition of the APC/C complex REACT:R-HSA-141430 |
| Inactivation of Cdc42 and Rac REACT:R-HSA-428543 |
| Inactivation, recovery and regulation of the phototransduction cascade REACT:R-HSA-2514859 |
| Incretin synthesis, secretion, and inactivation REACT:R-HSA-400508 |
| Infectious disease REACT:R-HSA-5663205 |
| Inflammasomes REACT:R-HSA-622312 |
| Inflammatory bowel disease (IBD) KEGG:hsa05321 |
| Inflammatory mediator regulation of TRP channels KEGG:hsa04750 |
| Influenza A KEGG:hsa05164 |
| Influenza Infection REACT:R-HSA-168254 |
| Influenza Life Cycle REACT:R-HSA-168255 |
| Influenza Viral RNA Transcription and Replication REACT:R-HSA-168273 |
| Influenza Virus Induced Apoptosis REACT:R-HSA-168277 |
| Inhibition of adenylate cyclase pathway REACT:R-HSA-997269 |
| Inhibition of Host mRNA Processing and RNA Silencing REACT:R-HSA-168315 |
| Inhibition of IFN-beta REACT:R-HSA-168888 |
| Inhibition of Interferon Synthesis REACT:R-HSA-168305 |
| Inhibition of PKR REACT:R-HSA-169131 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 REACT:R-HSA-113501 |
| Inhibition of Signaling by Overexpressed EGFR REACT:R-HSA-5638303 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components REACT:R-HSA-141405 |
| Inhibition of TSC complex formation by PKB REACT:R-HSA-165181 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits REACT:R-HSA-997272 |
| Initial triggering of complement REACT:R-HSA-166663 |
| Initiation of Nuclear Envelope Reformation REACT:R-HSA-2995383 |
| InlA-mediated entry of Listeria monocytogenes into host cells REACT:R-HSA-8876493 |
| InlB-mediated entry of Listeria monocytogenes into host cell REACT:R-HSA-8875360 |
| Innate Immune System REACT:R-HSA-168249 |
| Inosine monophosphate biosynthesis, PRPP + glutamine => IMP KEGG:hsa_M00048 |
| Inositol phosphate metabolism KEGG:hsa00562 |
| Inositol phosphate metabolism REACT:R-HSA-1483249 |
| Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol KEGG:hsa_M00131 |
| Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate KEGG:hsa_M00132 |
| Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 KEGG:hsa_M00130 |
| Inositol transporters REACT:R-HSA-429593 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate REACT:R-HSA-163754 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA REACT:R-HSA-428359 |
| Insulin processing REACT:R-HSA-264876 |
| Insulin receptor recycling REACT:R-HSA-77387 |
| Insulin receptor signalling cascade REACT:R-HSA-74751 |
| Insulin resistance KEGG:hsa04931 |
| Insulin secretion KEGG:hsa04911 |
| Insulin signaling pathway KEGG:hsa04910 |
| Integration of energy metabolism REACT:R-HSA-163685 |
| Integration of provirus REACT:R-HSA-162592 |
| Integration of viral DNA into host genomic DNA REACT:R-HSA-175567 |
| Integrin alphaIIb beta3 signaling REACT:R-HSA-354192 |
| Integrin cell surface interactions REACT:R-HSA-216083 |
| Interaction between L1 and Ankyrins REACT:R-HSA-445095 |
| Interaction between PHLDA1 and AURKA REACT:R-HSA-8854521 |
| Interactions of neurexins and neuroligins at synapses REACT:R-HSA-6794361 |
| Interactions of Rev with host cellular proteins REACT:R-HSA-177243 |
| Interactions of Tat with host cellular proteins REACT:R-HSA-176034 |
| Interactions of Vpr with host cellular proteins REACT:R-HSA-176033 |
| Interaction With Cumulus Cells REACT:R-HSA-2534343 |
| Interaction With The Zona Pellucida REACT:R-HSA-1300644 |
| Interconversion of 2-oxoglutarate and 2-hydroxyglutarate REACT:R-HSA-880009 |
| Interconversion of polyamines REACT:R-HSA-351200 |
| Interferon alpha/beta signaling REACT:R-HSA-909733 |
| Interferon gamma signaling REACT:R-HSA-877300 |
| Interferon Signaling REACT:R-HSA-913531 |
| Interleukin-10 signaling REACT:R-HSA-6783783 |
| Interleukin-12 signaling REACT:R-HSA-447115 |
| Interleukin-17 signaling REACT:R-HSA-448424 |
| Interleukin-19, 20, 22, 24 REACT:R-HSA-8854691 |
| Interleukin-1 processing REACT:R-HSA-448706 |
| Interleukin-1 signaling REACT:R-HSA-446652 |
| Interleukin-2 signaling REACT:R-HSA-451927 |
| Interleukin-3, 5 and GM-CSF signaling REACT:R-HSA-512988 |
| Interleukin-4 and 13 signaling REACT:R-HSA-6785807 |
| Interleukin-6 family signaling REACT:R-HSA-6783589 |
| Interleukin-6 signaling REACT:R-HSA-1059683 |
| Interleukin-7 signaling REACT:R-HSA-1266695 |
| Interleukin receptor SHC signaling REACT:R-HSA-912526 |
| Intestinal immune network for IgA production KEGG:hsa04672 |
| Intestinal infectious diseases REACT:R-HSA-8942233 |
| Intestinal saccharidase deficiencies REACT:R-HSA-5659898 |
| Intraflagellar transport REACT:R-HSA-5620924 |
| Intra-Golgi and retrograde Golgi-to-ER traffic REACT:R-HSA-6811442 |
| Intra-Golgi traffic REACT:R-HSA-6811438 |
| Intrinsic Pathway for Apoptosis REACT:R-HSA-109606 |
| Intrinsic Pathway of Fibrin Clot Formation REACT:R-HSA-140837 |
| Inwardly rectifying K+ channels REACT:R-HSA-1296065 |
| Ion channel transport REACT:R-HSA-983712 |
| Ion homeostasis REACT:R-HSA-5578775 |
| Ion influx/efflux at host-pathogen interface REACT:R-HSA-6803544 |
| Ionotropic activity of Kainate Receptors REACT:R-HSA-451306 |
| Ion transport by P-type ATPases REACT:R-HSA-936837 |
| IP3 and IP4 transport between cytosol and nucleus REACT:R-HSA-1855196 |
| IP6 and IP7 transport between cytosol and nucleus REACT:R-HSA-1855229 |
| IPs transport between cytosol and ER lumen REACT:R-HSA-1855184 |
| IPs transport between ER lumen and cytosol REACT:R-HSA-1855215 |
| IPs transport between ER lumen and nucleus REACT:R-HSA-1855156 |
| IPs transport between nucleus and cytosol REACT:R-HSA-1855170 |
| IPs transport between nucleus and ER lumen REACT:R-HSA-1855192 |
| IRAK1 recruits IKK complex REACT:R-HSA-937039 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation REACT:R-HSA-975144 |
| IRAK2 mediated activation of TAK1 complex REACT:R-HSA-937042 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation REACT:R-HSA-975163 |
| IRAK4 deficiency (TLR2/4) REACT:R-HSA-5603041 |
| IRAK4 deficiency (TLR5) REACT:R-HSA-5603037 |
| IRE1alpha activates chaperones REACT:R-HSA-381070 |
| IRF3 mediated activation of type 1 IFN REACT:R-HSA-1606341 |
| IRF3-mediated induction of type I IFN REACT:R-HSA-3270619 |
| Iron uptake and transport REACT:R-HSA-917937 |
| IRS activation REACT:R-HSA-74713 |
| IRS-mediated signalling REACT:R-HSA-112399 |
| IRS-related events triggered by IGF1R REACT:R-HSA-2428928 |
| ISG15 antiviral mechanism REACT:R-HSA-1169408 |
| JAK-STAT signaling KEGG:hsa_M00684 |
| Jak-STAT signaling pathway KEGG:hsa04630 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 REACT:R-HSA-450321 |
| Josephin domain DUBs REACT:R-HSA-5689877 |
| Keratan sulfate biosynthesis REACT:R-HSA-2022854 |
| Keratan sulfate degradation KEGG:hsa_M00079 |
| Keratan sulfate degradation REACT:R-HSA-2022857 |
| Keratan sulfate/keratin metabolism REACT:R-HSA-1638074 |
| Keratinization REACT:R-HSA-6805567 |
| Ketone body metabolism REACT:R-HSA-74182 |
| Kinesins REACT:R-HSA-983189 |
| KSRP (KHSRP) binds and destabilizes mRNA REACT:R-HSA-450604 |
| L13a-mediated translational silencing of Ceruloplasmin expression REACT:R-HSA-156827 |
| L1CAM interactions REACT:R-HSA-373760 |
| Lactose synthesis REACT:R-HSA-5653890 |
| Lactosylceramide biosynthesis KEGG:hsa_M00066 |
| Lagging Strand Synthesis REACT:R-HSA-69186 |
| Laminin interactions REACT:R-HSA-3000157 |
| Latent infection of Homo sapiens with Mycobacterium tuberculosis REACT:R-HSA-1222352 |
| Late Phase of HIV Life Cycle REACT:R-HSA-162599 |
| LDL-mediated lipid transport REACT:R-HSA-171052 |
| Leading Strand Synthesis REACT:R-HSA-69109 |
| Lectin pathway of complement activation REACT:R-HSA-166662 |
| Legionellosis KEGG:hsa05134 |
| Leishmaniasis KEGG:hsa05140 |
| Leucine degradation, leucine => acetoacetate + acetyl-CoA KEGG:hsa_M00036 |
| Leukocyte transendothelial migration KEGG:hsa04670 |
| Leukotriene receptors REACT:R-HSA-391906 |
| LGI-ADAM interactions REACT:R-HSA-5682910 |
| Ligand-dependent caspase activation REACT:R-HSA-140534 |
| Ligand-gated ion channel transport REACT:R-HSA-975298 |
| Ligand-independent caspase activation via DCC REACT:R-HSA-418889 |
| Ligand-receptor interactions REACT:R-HSA-5632681 |
| Linoleic acid (LA) metabolism REACT:R-HSA-2046105 |
| Linoleic acid metabolism KEGG:hsa00591 |
| Lipid digestion, mobilization, and transport REACT:R-HSA-73923 |
| Lipoic acid metabolism KEGG:hsa00785 |
| Lipoprotein metabolism REACT:R-HSA-174824 |
| Listeria monocytogenes entry into host cells REACT:R-HSA-8876384 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions REACT:R-HSA-446343 |
| Longevity regulating pathway KEGG:hsa04211 |
| Longevity regulating pathway - multiple species KEGG:hsa04213 |
| Long-term depression KEGG:hsa04730 |
| Long-term potentiation KEGG:hsa04720 |
| Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling REACT:R-HSA-2644607 |
| Loss of Function of SMAD2/3 in Cancer REACT:R-HSA-3304349 |
| Loss of Function of SMAD4 in Cancer REACT:R-HSA-3304347 |
| Loss of Function of TGFBR1 in Cancer REACT:R-HSA-3656534 |
| Loss of Function of TGFBR2 in Cancer REACT:R-HSA-3642278 |
| Loss of Nlp from mitotic centrosomes REACT:R-HSA-380259 |
| Loss of proteins required for interphase microtubule organization from the centrosome REACT:R-HSA-380284 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production REACT:R-HSA-3134973 |
| Lsm 1-7 complex KEGG:hsa_M00397 |
| Lsm 2-8 complex KEGG:hsa_M00396 |
| Lysine biosynthesis KEGG:hsa00300 |
| Lysine catabolism REACT:R-HSA-71064 |
| Lysine degradation KEGG:hsa00310 |
| Lysine degradation, lysine => saccharopine => acetoacetyl-CoA KEGG:hsa_M00032 |
| Lysosomal glycogen catabolism REACT:R-HSA-5357572 |
| Lysosomal oligosaccharide catabolism REACT:R-HSA-8853383 |
| Lysosome KEGG:hsa04142 |
| Lysosome Vesicle Biogenesis REACT:R-HSA-432720 |
| Lysosphingolipid and LPA receptors REACT:R-HSA-419408 |
| Macroautophagy REACT:R-HSA-1632852 |
| Major pathway of rRNA processing in the nucleolus and cytosol REACT:R-HSA-6791226 |
| Malaria KEGG:hsa05144 |
| Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA KEGG:hsa_M00013 |
| Mannose type O-glycan biosynthesis KEGG:hsa00515 |
| MAP2K and MAPK activation REACT:R-HSA-5674135 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation REACT:R-HSA-5684264 |
| MAPK1 (ERK2) activation REACT:R-HSA-112411 |
| MAPK1/MAPK3 signaling REACT:R-HSA-5684996 |
| MAPK3 (ERK1) activation REACT:R-HSA-110056 |
| MAPK6/MAPK4 signaling REACT:R-HSA-5687128 |
| MAPK (ERK1/2) signaling KEGG:hsa_M00687 |
| MAPK (ERK5) signaling KEGG:hsa_M00690 |
| MAPK family signaling cascades REACT:R-HSA-5683057 |
| MAP kinase activation in TLR cascade REACT:R-HSA-450294 |
| MAPK (JNK) signaling KEGG:hsa_M00688 |
| MAPK (p38) signaling KEGG:hsa_M00689 |
| MAPK signaling pathway KEGG:hsa04010 |
| MAPK targets/ Nuclear events mediated by MAP kinases REACT:R-HSA-450282 |
| MASTL Facilitates Mitotic Progression REACT:R-HSA-2465910 |
| Maturity onset diabetes of the young KEGG:hsa04950 |
| MCM complex KEGG:hsa_M00285 |
| Measles KEGG:hsa05162 |
| Meiosis REACT:R-HSA-1500620 |
| Meiotic recombination REACT:R-HSA-912446 |
| Meiotic synapsis REACT:R-HSA-1221632 |
| Melanin biosynthesis REACT:R-HSA-5662702 |
| Melanogenesis KEGG:hsa04916 |
| Melanoma KEGG:hsa05218 |
| Melatonin biosynthesis, tryptophan => serotonin => melatonin KEGG:hsa_M00037 |
| Membrane binding and targetting of GAG proteins REACT:R-HSA-174490 |
| Membrane Trafficking REACT:R-HSA-199991 |
| Metabolic disorders of biological oxidation enzymes REACT:R-HSA-5579029 |
| Metabolic pathways KEGG:hsa01100 |
| Metabolism REACT:R-HSA-1430728 |
| Metabolism of amino acids and derivatives REACT:R-HSA-71291 |
| Metabolism of Angiotensinogen to Angiotensins REACT:R-HSA-2022377 |
| Metabolism of carbohydrates REACT:R-HSA-71387 |
| Metabolism of fat-soluble vitamins REACT:R-HSA-6806667 |
| Metabolism of folate and pterines REACT:R-HSA-196757 |
| Metabolism of ingested H2SeO4 and H2SeO3 into H2Se REACT:R-HSA-2408550 |
| Metabolism of ingested MeSeO2H into MeSeH REACT:R-HSA-5263617 |
| Metabolism of ingested SeMet, Sec, MeSec into H2Se REACT:R-HSA-2408508 |
| Metabolism of lipids and lipoproteins REACT:R-HSA-556833 |
| Metabolism of nitric oxide REACT:R-HSA-202131 |
| Metabolism of non-coding RNA REACT:R-HSA-194441 |
| Metabolism of nucleotides REACT:R-HSA-15869 |
| Metabolism of polyamines REACT:R-HSA-351202 |
| Metabolism of porphyrins REACT:R-HSA-189445 |
| Metabolism of proteins REACT:R-HSA-392499 |
| Metabolism of serotonin REACT:R-HSA-380612 |
| Metabolism of steroid hormones REACT:R-HSA-196071 |
| Metabolism of vitamin K REACT:R-HSA-6806664 |
| Metabolism of vitamins and cofactors REACT:R-HSA-196854 |
| Metabolism of water-soluble vitamins and cofactors REACT:R-HSA-196849 |
| Metabolism of xenobiotics by cytochrome P450 KEGG:hsa00980 |
| MET activates PI3K/AKT signaling REACT:R-HSA-8851907 |
| MET activates PTK2 signaling REACT:R-HSA-8874081 |
| MET activates PTPN11 REACT:R-HSA-8865999 |
| MET activates RAP1 and RAC1 REACT:R-HSA-8875555 |
| MET activates RAS signaling REACT:R-HSA-8851805 |
| MET activates STAT3 REACT:R-HSA-8875791 |
| Metal ion SLC transporters REACT:R-HSA-425410 |
| Metalloprotease DUBs REACT:R-HSA-5689901 |
| Metallothioneins bind metals REACT:R-HSA-5661231 |
| Metal sequestration by antimicrobial proteins REACT:R-HSA-6799990 |
| Methionine degradation KEGG:hsa_M00035 |
| Methionine salvage pathway KEGG:hsa_M00034 |
| Methionine salvage pathway REACT:R-HSA-1237112 |
| Methylation REACT:R-HSA-156581 |
| Methylation of MeSeH for excretion REACT:R-HSA-2408552 |
| MET interacts with TNS proteins REACT:R-HSA-8875513 |
| MET promotes cell motility REACT:R-HSA-8875878 |
| MET Receptor Activation REACT:R-HSA-6806942 |
| MET receptor recycling REACT:R-HSA-8875656 |
| M/G1 Transition REACT:R-HSA-68874 |
| MGMT-mediated DNA damage reversal REACT:R-HSA-5657655 |
| MHC class II antigen presentation REACT:R-HSA-2132295 |
| MicroRNA (miRNA) biogenesis REACT:R-HSA-203927 |
| MicroRNAs in cancer KEGG:hsa05206 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane REACT:R-HSA-190840 |
| Mineral absorption KEGG:hsa04978 |
| Mineralocorticoid biosynthesis REACT:R-HSA-193993 |
| Minus-strand DNA synthesis REACT:R-HSA-164516 |
| Miscellaneous digestion events REACT:R-HSA-8935690 |
| Miscellaneous substrates REACT:R-HSA-211958 |
| Miscellaneous transport and binding events REACT:R-HSA-5223345 |
| Mismatch repair KEGG:hsa03430 |
| Mismatch Repair REACT:R-HSA-5358508 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) REACT:R-HSA-5358606 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) REACT:R-HSA-5358565 |
| Misspliced GSK3beta mutants stabilize beta-catenin REACT:R-HSA-5339716 |
| Misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling REACT:R-HSA-5339717 |
| Mitochondrial ABC transporters REACT:R-HSA-1369007 |
| Mitochondrial biogenesis REACT:R-HSA-1592230 |
| Mitochondrial Fatty Acid Beta-Oxidation REACT:R-HSA-77289 |
| mitochondrial fatty acid beta-oxidation of saturated fatty acids REACT:R-HSA-77286 |
| mitochondrial fatty acid beta-oxidation of unsaturated fatty acids REACT:R-HSA-77288 |
| Mitochondrial iron-sulfur cluster biogenesis REACT:R-HSA-1362409 |
| Mitochondrial protein import REACT:R-HSA-1268020 |
| Mitochondrial transcription initiation REACT:R-HSA-163282 |
| Mitochondrial transcription termination REACT:R-HSA-163316 |
| Mitochondrial translation REACT:R-HSA-5368287 |
| Mitochondrial translation elongation REACT:R-HSA-5389840 |
| Mitochondrial translation initiation REACT:R-HSA-5368286 |
| Mitochondrial translation termination REACT:R-HSA-5419276 |
| Mitochondrial tRNA aminoacylation REACT:R-HSA-379726 |
| Mitochondrial Uncoupling Proteins REACT:R-HSA-166187 |
| Mitophagy REACT:R-HSA-5205647 |
| Mitophagy - animal KEGG:hsa04137 |
| Mitotic Anaphase REACT:R-HSA-68882 |
| Mitotic G1-G1/S phases REACT:R-HSA-453279 |
| Mitotic G2-G2/M phases REACT:R-HSA-453274 |
| Mitotic Metaphase/Anaphase Transition REACT:R-HSA-68881 |
| Mitotic Metaphase and Anaphase REACT:R-HSA-2555396 |
| Mitotic Prometaphase REACT:R-HSA-68877 |
| Mitotic Prophase REACT:R-HSA-68875 |
| Mitotic Spindle Checkpoint REACT:R-HSA-69618 |
| Mitotic Telophase/Cytokinesis REACT:R-HSA-68884 |
| Molecules associated with elastic fibres REACT:R-HSA-2129379 |
| Molybdenum cofactor biosynthesis REACT:R-HSA-947581 |
| Morphine addiction KEGG:hsa05032 |
| M Phase REACT:R-HSA-68886 |
| MPS I - Hurler syndrome REACT:R-HSA-2206302 |
| MPS II - Hunter syndrome REACT:R-HSA-2206296 |
| MPS IIIA - Sanfilippo syndrome A REACT:R-HSA-2206307 |
| MPS IIIB - Sanfilippo syndrome B REACT:R-HSA-2206282 |
| MPS IIIC - Sanfilippo syndrome C REACT:R-HSA-2206291 |
| MPS IIID - Sanfilippo syndrome D REACT:R-HSA-2206305 |
| MPS IV - Morquio syndrome A REACT:R-HSA-2206290 |
| MPS IV - Morquio syndrome B REACT:R-HSA-2206308 |
| MPS IX - Natowicz syndrome REACT:R-HSA-2206280 |
| MPS VII - Sly syndrome REACT:R-HSA-2206292 |
| MPS VI - Maroteaux-Lamy syndrome REACT:R-HSA-2206285 |
| mRNA 3'-end processing REACT:R-HSA-72187 |
| mRNA Capping REACT:R-HSA-72086 |
| mRNA decay by 3' to 5' exoribonuclease REACT:R-HSA-429958 |
| mRNA decay by 5' to 3' exoribonuclease REACT:R-HSA-430039 |
| mRNA Editing REACT:R-HSA-75072 |
| mRNA Editing: A to I Conversion REACT:R-HSA-75064 |
| mRNA Editing: C to U Conversion REACT:R-HSA-72200 |
| mRNA Splicing REACT:R-HSA-72172 |
| mRNA Splicing - Major Pathway REACT:R-HSA-72163 |
| mRNA Splicing - Minor Pathway REACT:R-HSA-72165 |
| mRNA surveillance pathway KEGG:hsa03015 |
| MRN complex KEGG:hsa_M00291 |
| Mtb iron assimilation by chelation REACT:R-HSA-1222449 |
| mTORC1-mediated signalling REACT:R-HSA-166208 |
| mTOR signaling pathway KEGG:hsa04150 |
| mTOR signalling REACT:R-HSA-165159 |
| Mucin type O-glycan biosynthesis KEGG:hsa00512 |
| Mucopolysaccharidoses REACT:R-HSA-2206281 |
| Multifunctional anion exchangers REACT:R-HSA-427601 |
| Muscarinic acetylcholine receptors REACT:R-HSA-390648 |
| Muscle contraction REACT:R-HSA-397014 |
| MyD88 cascade initiated on plasma membrane REACT:R-HSA-975871 |
| MyD88 deficiency (TLR2/4) REACT:R-HSA-5602498 |
| MyD88 deficiency (TLR5) REACT:R-HSA-5602680 |
| MyD88 dependent cascade initiated on endosome REACT:R-HSA-975155 |
| MyD88-independent TLR3/TLR4 cascade REACT:R-HSA-166166 |
| MyD88:Mal cascade initiated on plasma membrane REACT:R-HSA-166058 |
| Myoclonic epilepsy of Lafora REACT:R-HSA-3785653 |
| Myogenesis REACT:R-HSA-525793 |
| Na+/Cl- dependent neurotransmitter transporters REACT:R-HSA-442660 |
| NADE modulates death signalling REACT:R-HSA-205025 |
| Na+-dependent glucose transporters REACT:R-HSA-428808 |
| NADH dehydrogenase (ubiquinone) 1 alpha subcomplex KEGG:hsa_M00146 |
| NADH dehydrogenase (ubiquinone) 1 beta subcomplex KEGG:hsa_M00147 |
| NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria KEGG:hsa_M00143 |
| NADH:ubiquinone oxidoreductase, mitochondria KEGG:hsa_M00142 |
| NADPH regeneration REACT:R-HSA-389542 |
| Natural killer cell mediated cytotoxicity KEGG:hsa04650 |
| NCAM1 interactions REACT:R-HSA-419037 |
| NCAM signaling for neurite out-growth REACT:R-HSA-375165 |
| Nectin/Necl trans heterodimerization REACT:R-HSA-420597 |
| Nef and signal transduction REACT:R-HSA-164944 |
| Nef Mediated CD4 Down-regulation REACT:R-HSA-167590 |
| Nef Mediated CD8 Down-regulation REACT:R-HSA-182218 |
| Nef mediated downregulation of CD28 cell surface expression REACT:R-HSA-164939 |
| Nef mediated downregulation of MHC class I complex cell surface expression REACT:R-HSA-164940 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters REACT:R-HSA-164938 |
| Negative epigenetic regulation of rRNA expression REACT:R-HSA-5250941 |
| Negative feedback regulation of MAPK pathway REACT:R-HSA-5674499 |
| Negative regulation of activity of TFAP2 (AP-2) family transcription factors REACT:R-HSA-8866904 |
| Negative regulation of FGFR1 signaling REACT:R-HSA-5654726 |
| Negative regulation of FGFR2 signaling REACT:R-HSA-5654727 |
| Negative regulation of FGFR3 signaling REACT:R-HSA-5654732 |
| Negative regulation of FGFR4 signaling REACT:R-HSA-5654733 |
| Negative regulation of MAPK pathway REACT:R-HSA-5675221 |
| Negative regulation of MET activity REACT:R-HSA-6807004 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins REACT:R-HSA-5368598 |
| Negative regulation of TCF-dependent signaling by WNT ligand antagonists REACT:R-HSA-3772470 |
| Negative regulation of the PI3K/AKT network REACT:R-HSA-199418 |
| Negative regulators of RIG-I/MDA5 signaling REACT:R-HSA-936440 |
| Neomycin, kanamycin and gentamicin biosynthesis KEGG:hsa00524 |
| Nephrin interactions REACT:R-HSA-373753 |
| NEP/NS2 Interacts with the Cellular Export Machinery REACT:R-HSA-168333 |
| Netrin-1 signaling REACT:R-HSA-373752 |
| Netrin mediated repulsion signals REACT:R-HSA-418886 |
| Neuroactive ligand-receptor interaction KEGG:hsa04080 |
| Neurodegenerative Diseases REACT:R-HSA-8863678 |
| Neurofascin interactions REACT:R-HSA-447043 |
| Neuronal System REACT:R-HSA-112316 |
| Neurophilin interactions with VEGF and VEGFR REACT:R-HSA-194306 |
| Neurotoxicity of clostridium toxins REACT:R-HSA-168799 |
| Neurotransmitter Clearance In The Synaptic Cleft REACT:R-HSA-112311 |
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell REACT:R-HSA-112314 |
| Neurotransmitter Release Cycle REACT:R-HSA-112310 |
| Neurotransmitter uptake and Metabolism In Glial Cells REACT:R-HSA-112313 |
| Neurotrophin signaling pathway KEGG:hsa04722 |
| Neutrophil degranulation REACT:R-HSA-6798695 |
| NFG and proNGF binds to p75NTR REACT:R-HSA-205017 |
| NF-kappa B signaling pathway KEGG:hsa04064 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 REACT:R-HSA-933543 |
| NF-kB is activated and signals survival REACT:R-HSA-209560 |
| NGF-independant TRKA activation REACT:R-HSA-187024 |
| NGF processing REACT:R-HSA-167060 |
| NGF signalling via TRKA from the plasma membrane REACT:R-HSA-187037 |
| N-Glycan antennae elongation REACT:R-HSA-975577 |
| N-glycan antennae elongation in the medial/trans-Golgi REACT:R-HSA-975576 |
| N-Glycan biosynthesis KEGG:hsa00510 |
| N-glycan biosynthesis, complex type KEGG:hsa_M00075 |
| N-glycan precursor biosynthesis KEGG:hsa_M00055 |
| N-glycan precursor trimming KEGG:hsa_M00073 |
| N-glycan trimming and elongation in the cis-Golgi REACT:R-HSA-964739 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle REACT:R-HSA-532668 |
| N-glycosylation by oligosaccharyltransferase KEGG:hsa_M00072 |
| Nicotinamide salvaging REACT:R-HSA-197264 |
| Nicotinate and nicotinamide metabolism KEGG:hsa00760 |
| Nicotinate metabolism REACT:R-HSA-196807 |
| Nicotine addiction KEGG:hsa05033 |
| NIK-->noncanonical NF-kB signaling REACT:R-HSA-5676590 |
| Nitric oxide stimulates guanylate cyclase REACT:R-HSA-392154 |
| Nitrogen metabolism KEGG:hsa00910 |
| NOD1/2 Signaling Pathway REACT:R-HSA-168638 |
| NOD-like receptor signaling pathway KEGG:hsa04621 |
| Non-alcoholic fatty liver disease (NAFLD) KEGG:hsa04932 |
| Non-homologous end-joining KEGG:hsa03450 |
| Nonhomologous End-Joining (NHEJ) REACT:R-HSA-5693571 |
| Non-integrin membrane-ECM interactions REACT:R-HSA-3000171 |
| Nonsense-Mediated Decay (NMD) REACT:R-HSA-927802 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) REACT:R-HSA-975957 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) REACT:R-HSA-975956 |
| Non-small cell lung cancer KEGG:hsa05223 |
| NoRC negatively regulates rRNA expression REACT:R-HSA-427413 |
| Norepinephrine Neurotransmitter Release Cycle REACT:R-HSA-181430 |
| NOSIP mediated eNOS trafficking REACT:R-HSA-203754 |
| NOSTRIN mediated eNOS trafficking REACT:R-HSA-203641 |
| NOTCH1 Intracellular Domain Regulates Transcription REACT:R-HSA-2122947 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus REACT:R-HSA-2979096 |
| NOTCH2 intracellular domain regulates transcription REACT:R-HSA-2197563 |
| Notch-HLH transcription pathway REACT:R-HSA-350054 |
| Notch signaling KEGG:hsa_M00682 |
| Notch signaling pathway KEGG:hsa04330 |
| NR1D1 (REV-ERBA) represses gene expression REACT:R-HSA-1368071 |
| NRAGE signals death through JNK REACT:R-HSA-193648 |
| NrCAM interactions REACT:R-HSA-447038 |
| NRIF signals cell death from the nucleus REACT:R-HSA-205043 |
| NS1 Mediated Effects on Host Pathways REACT:R-HSA-168276 |
| Nuclear Envelope Breakdown REACT:R-HSA-2980766 |
| Nuclear Envelope Reassembly REACT:R-HSA-2995410 |
| Nuclear Events (kinase and transcription factor activation) REACT:R-HSA-198725 |
| Nuclear import of Rev protein REACT:R-HSA-180746 |
| Nuclear pore complex KEGG:hsa_M00427 |
| Nuclear Pore Complex (NPC) Disassembly REACT:R-HSA-3301854 |
| Nuclear Receptor transcription pathway REACT:R-HSA-383280 |
| Nuclear signaling by ERBB4 REACT:R-HSA-1251985 |
| Nucleosome assembly REACT:R-HSA-774815 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways REACT:R-HSA-168643 |
| Nucleotide excision repair KEGG:hsa03420 |
| Nucleotide Excision Repair REACT:R-HSA-5696398 |
| Nucleotide-like (purinergic) receptors REACT:R-HSA-418038 |
| Nucleotide sugar biosynthesis, eukaryotes KEGG:hsa_M00361 |
| Nucleotide sugar biosynthesis, galactose => UDP-galactose KEGG:hsa_M00554 |
| Nucleotide sugar biosynthesis, glucose => UDP-glucose KEGG:hsa_M00549 |
| O2/CO2 exchange in erythrocytes REACT:R-HSA-1480926 |
| O-glycan biosynthesis, mucin type core KEGG:hsa_M00056 |
| O-glycosylation of TSR domain-containing proteins REACT:R-HSA-5173214 |
| Olfactory Signaling Pathway REACT:R-HSA-381753 |
| Olfactory transduction KEGG:hsa04740 |
| Oligomerization of connexins into connexons REACT:R-HSA-190704 |
| O-linked glycosylation REACT:R-HSA-5173105 |
| O-linked glycosylation of mucins REACT:R-HSA-913709 |
| Oncogene Induced Senescence REACT:R-HSA-2559585 |
| Oncogenic MAPK signaling REACT:R-HSA-6802957 |
| One carbon pool by folate KEGG:hsa00670 |
| Oocyte meiosis KEGG:hsa04114 |
| Opioid Signalling REACT:R-HSA-111885 |
| Opsins REACT:R-HSA-419771 |
| Orc1 removal from chromatin REACT:R-HSA-68949 |
| Orexin and neuropeptides FF and QRFP bind to their respective receptors REACT:R-HSA-389397 |
| Organelle biogenesis and maintenance REACT:R-HSA-1852241 |
| Organic anion transport REACT:R-HSA-561048 |
| Organic anion transporters REACT:R-HSA-428643 |
| Organic cation/anion/zwitterion transport REACT:R-HSA-549132 |
| Organic cation transport REACT:R-HSA-549127 |
| Origin recognition complex KEGG:hsa_M00284 |
| Osteoclast differentiation KEGG:hsa04380 |
| Other glycan degradation KEGG:hsa00511 |
| Other semaphorin interactions REACT:R-HSA-416700 |
| Other types of O-glycan biosynthesis KEGG:hsa00514 |
| Ovarian steroidogenesis KEGG:hsa04913 |
| Ovarian tumor domain proteases REACT:R-HSA-5689896 |
| Oxidative phosphorylation KEGG:hsa00190 |
| Oxidative Stress Induced Senescence REACT:R-HSA-2559580 |
| Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha REACT:R-HSA-1234162 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha REACT:R-HSA-1234176 |
| Oxytocin signaling pathway KEGG:hsa04921 |
| p130Cas linkage to MAPK signaling for integrins REACT:R-HSA-372708 |
| P2Y receptors REACT:R-HSA-417957 |
| p38MAPK events REACT:R-HSA-171007 |
| p53-Dependent G1 DNA Damage Response REACT:R-HSA-69563 |
| p53-Dependent G1/S DNA damage checkpoint REACT:R-HSA-69580 |
| p53-Independent DNA Damage Response REACT:R-HSA-69610 |
| p53-Independent G1/S DNA damage checkpoint REACT:R-HSA-69613 |
| p53 signaling pathway KEGG:hsa04115 |
| p75NTR negatively regulates cell cycle via SC1 REACT:R-HSA-193670 |
| p75 NTR receptor-mediated signalling REACT:R-HSA-193704 |
| p75NTR recruits signalling complexes REACT:R-HSA-209543 |
| p75NTR regulates axonogenesis REACT:R-HSA-193697 |
| p75NTR signals via NF-kB REACT:R-HSA-193639 |
| p97-Ufd1-Npl4 complex KEGG:hsa_M00400 |
| Packaging of Eight RNA Segments REACT:R-HSA-168303 |
| Packaging Of Telomere Ends REACT:R-HSA-171306 |
| Pancreatic cancer KEGG:hsa05212 |
| Pancreatic secretion KEGG:hsa04972 |
| Pantothenate and CoA biosynthesis KEGG:hsa00770 |
| PAOs oxidise polyamines to amines REACT:R-HSA-141334 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF REACT:R-HSA-6802955 |
| Parkinson's disease KEGG:hsa05012 |
| Passive transport by Aquaporins REACT:R-HSA-432047 |
| Pathogenic Escherichia coli infection KEGG:hsa05130 |
| Pathways in cancer KEGG:hsa05200 |
| Pausing and recovery of HIV elongation REACT:R-HSA-167290 |
| Pausing and recovery of Tat-mediated HIV elongation REACT:R-HSA-167238 |
| PCNA-Dependent Long Patch Base Excision Repair REACT:R-HSA-5651801 |
| PCP/CE pathway REACT:R-HSA-4086400 |
| PD-1 signaling REACT:R-HSA-389948 |
| PDE3B signalling REACT:R-HSA-165160 |
| PECAM1 interactions REACT:R-HSA-210990 |
| Pentose and glucuronate interconversions KEGG:hsa00040 |
| Pentose phosphate pathway KEGG:hsa00030 |
| Pentose phosphate pathway disease REACT:R-HSA-6791465 |
| Pentose phosphate pathway (hexose monophosphate shunt) REACT:R-HSA-71336 |
| Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P KEGG:hsa_M00007 |
| Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P KEGG:hsa_M00006 |
| Pentose phosphate pathway (Pentose phosphate cycle) KEGG:hsa_M00004 |
| Peptide chain elongation REACT:R-HSA-156902 |
| Peptide hormone biosynthesis REACT:R-HSA-209952 |
| Peptide hormone metabolism REACT:R-HSA-2980736 |
| Peptide ligand-binding receptors REACT:R-HSA-375276 |
| PERK regulates gene expression REACT:R-HSA-381042 |
| Peroxisomal lipid metabolism REACT:R-HSA-390918 |
| Peroxisome KEGG:hsa04146 |
| Pertussis KEGG:hsa05133 |
| Phagosome KEGG:hsa04145 |
| Phase 0 - rapid depolarisation REACT:R-HSA-5576892 |
| Phase 1 - Functionalization of compounds REACT:R-HSA-211945 |
| Phase 1 - inactivation of fast Na+ channels REACT:R-HSA-5576894 |
| Phase 2 - plateau phase REACT:R-HSA-5576893 |
| Phase 3 - rapid repolarisation REACT:R-HSA-5576890 |
| Phase 4 - resting membrane potential REACT:R-HSA-5576886 |
| Phase II conjugation REACT:R-HSA-156580 |
| Phenylalanine and tyrosine catabolism REACT:R-HSA-71182 |
| Phenylalanine metabolism KEGG:hsa00360 |
| Phenylalanine, tyrosine and tryptophan biosynthesis KEGG:hsa00400 |
| Phenylketonuria REACT:R-HSA-2160456 |
| Phosphate bond hydrolysis by NTPDase proteins REACT:R-HSA-8850843 |
| Phosphate bond hydrolysis by NUDT proteins REACT:R-HSA-2393930 |
| Phosphatidylcholine (PC) biosynthesis, choline => PC KEGG:hsa_M00090 |
| Phosphatidylcholine (PC) biosynthesis, PE => PC KEGG:hsa_M00091 |
| Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE KEGG:hsa_M00092 |
| Phosphatidylinositol signaling system KEGG:hsa04070 |
| Phospholipase C-mediated cascade: FGFR1 REACT:R-HSA-5654219 |
| Phospholipase C-mediated cascade; FGFR2 REACT:R-HSA-5654221 |
| Phospholipase C-mediated cascade; FGFR3 REACT:R-HSA-5654227 |
| Phospholipase C-mediated cascade; FGFR4 REACT:R-HSA-5654228 |
| Phospholipase D signaling pathway KEGG:hsa04072 |
| Phospholipid metabolism REACT:R-HSA-1483257 |
| Phosphonate and phosphinate metabolism KEGG:hsa00440 |
| phospho-PLA2 pathway REACT:R-HSA-111995 |
| Phosphorylation of CD3 and TCR zeta chains REACT:R-HSA-202427 |
| Phosphorylation of Emi1 REACT:R-HSA-176417 |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes REACT:R-HSA-69200 |
| Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes REACT:R-HSA-170145 |
| Phosphorylation of the APC/C REACT:R-HSA-176412 |
| phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex REACT:R-HSA-4839743 |
| Phototransduction KEGG:hsa04744 |
| Physiological factors REACT:R-HSA-5578768 |
| PI3K/AKT activation REACT:R-HSA-198203 |
| PI3K-Akt signaling KEGG:hsa_M00676 |
| PI3K/AKT Signaling in Cancer REACT:R-HSA-2219528 |
| PI3K-Akt signaling pathway KEGG:hsa04151 |
| PI3K Cascade REACT:R-HSA-109704 |
| PI-3K cascade:FGFR1 REACT:R-HSA-5654689 |
| PI-3K cascade:FGFR2 REACT:R-HSA-5654695 |
| PI-3K cascade:FGFR3 REACT:R-HSA-5654710 |
| PI-3K cascade:FGFR4 REACT:R-HSA-5654720 |
| PI3K events in ERBB2 signaling REACT:R-HSA-1963642 |
| PI3K events in ERBB4 signaling REACT:R-HSA-1250342 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling REACT:R-HSA-6811558 |
| PI5P Regulates TP53 Acetylation REACT:R-HSA-6811555 |
| PI and PC transport between ER and Golgi membranes REACT:R-HSA-1483196 |
| PI Metabolism REACT:R-HSA-1483255 |
| Pink/Parkin Mediated Mitophagy REACT:R-HSA-5205685 |
| PIP3 activates AKT signaling REACT:R-HSA-1257604 |
| PIPs transport between early and late endosome membranes REACT:R-HSA-1660502 |
| PIPs transport between early endosome and Golgi membranes REACT:R-HSA-1660537 |
| PIPs transport between Golgi and plasma membranes REACT:R-HSA-1660510 |
| PIPs transport between late endosome and Golgi membranes REACT:R-HSA-1660508 |
| PIPs transport between plasma and early endosome membranes REACT:R-HSA-1660524 |
| PIWI-interacting RNA (piRNA) biogenesis REACT:R-HSA-5601884 |
| PKA activation REACT:R-HSA-163615 |
| PKA activation in glucagon signalling REACT:R-HSA-164378 |
| PKA-mediated phosphorylation of CREB REACT:R-HSA-111931 |
| PKA-mediated phosphorylation of key metabolic factors REACT:R-HSA-163358 |
| PKB-mediated events REACT:R-HSA-109703 |
| PKMTs methylate histone lysines REACT:R-HSA-3214841 |
| Plasmalogen biosynthesis REACT:R-HSA-75896 |
| Platelet activation KEGG:hsa04611 |
| Platelet activation, signaling and aggregation REACT:R-HSA-76002 |
| Platelet Adhesion to exposed collagen REACT:R-HSA-75892 |
| Platelet Aggregation (Plug Formation) REACT:R-HSA-76009 |
| Platelet calcium homeostasis REACT:R-HSA-418360 |
| Platelet degranulation REACT:R-HSA-114608 |
| Platelet homeostasis REACT:R-HSA-418346 |
| Platelet sensitization by LDL REACT:R-HSA-432142 |
| Platinum drug resistance KEGG:hsa01524 |
| PLC beta mediated events REACT:R-HSA-112043 |
| PLCG1 events in ERBB2 signaling REACT:R-HSA-1251932 |
| PLC-gamma1 signalling REACT:R-HSA-167021 |
| Plus-strand DNA synthesis REACT:R-HSA-164525 |
| POLB-Dependent Long Patch Base Excision Repair REACT:R-HSA-110362 |
| Polo-like kinase mediated events REACT:R-HSA-156711 |
| Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine KEGG:hsa_M00133 |
| Polyamine biosynthesis, arginine => ornithine => putrescine KEGG:hsa_M00134 |
| Polymerase switching REACT:R-HSA-69091 |
| Polymerase switching on the C-strand of the telomere REACT:R-HSA-174411 |
| Porphyrin and chlorophyll metabolism KEGG:hsa00860 |
| Positive epigenetic regulation of rRNA expression REACT:R-HSA-5250913 |
| Post-chaperonin tubulin folding pathway REACT:R-HSA-389977 |
| Post NMDA receptor activation events REACT:R-HSA-438064 |
| Postsynaptic nicotinic acetylcholine receptors REACT:R-HSA-622327 |
| Post-transcriptional silencing by small RNAs REACT:R-HSA-426496 |
| Post-translational modification: synthesis of GPI-anchored proteins REACT:R-HSA-163125 |
| Post-translational protein modification REACT:R-HSA-597592 |
| Potassium Channels REACT:R-HSA-1296071 |
| Potassium transport channels REACT:R-HSA-1296067 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation REACT:R-HSA-2892247 |
| POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation REACT:R-HSA-2892245 |
| PP2A-mediated dephosphorylation of key metabolic factors REACT:R-HSA-163767 |
| PPARA activates gene expression REACT:R-HSA-1989781 |
| PPAR signaling pathway KEGG:hsa03320 |
| PRC2 methylates histones and DNA REACT:R-HSA-212300 |
| Prefoldin mediated transfer of substrate to CCT/TriC REACT:R-HSA-389957 |
| Pregnenolone biosynthesis REACT:R-HSA-196108 |
| Pre-NOTCH Expression and Processing REACT:R-HSA-1912422 |
| Pre-NOTCH Processing in Golgi REACT:R-HSA-1912420 |
| Pre-NOTCH Processing in the Endoplasmic Reticulum REACT:R-HSA-1912399 |
| Pre-NOTCH Transcription and Translation REACT:R-HSA-1912408 |
| Presynaptic function of Kainate receptors REACT:R-HSA-500657 |
| Presynaptic nicotinic acetylcholine receptors REACT:R-HSA-622323 |
| Presynaptic phase of homologous DNA pairing and strand exchange REACT:R-HSA-5693616 |
| Primary bile acid biosynthesis KEGG:hsa00120 |
| Primary immunodeficiency KEGG:hsa05340 |
| Prion diseases KEGG:hsa05020 |
| Processing and activation of SUMO REACT:R-HSA-3215018 |
| Processing of Capped Intron-Containing Pre-mRNA REACT:R-HSA-72203 |
| Processing of Capped Intronless Pre-mRNA REACT:R-HSA-75067 |
| Processing of DNA double-strand break ends REACT:R-HSA-5693607 |
| Processing of Intronless Pre-mRNAs REACT:R-HSA-77595 |
| Processive synthesis on the C-strand of the telomere REACT:R-HSA-174414 |
| Processive synthesis on the lagging strand REACT:R-HSA-69183 |
| Progesterone-mediated oocyte maturation KEGG:hsa04914 |
| Programmed Cell Death REACT:R-HSA-5357801 |
| Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 REACT:R-HSA-964827 |
| Prolactin receptor signaling REACT:R-HSA-1170546 |
| Prolactin signaling pathway KEGG:hsa04917 |
| Proline biosynthesis, glutamate => proline KEGG:hsa_M00015 |
| Proline catabolism REACT:R-HSA-70688 |
| Prolonged ERK activation events REACT:R-HSA-169893 |
| Propanoate metabolism KEGG:hsa00640 |
| Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA KEGG:hsa_M00741 |
| Propionyl-CoA catabolism REACT:R-HSA-71032 |
| Prostacyclin signalling through prostacyclin receptor REACT:R-HSA-392851 |
| Prostanoid ligand receptors REACT:R-HSA-391908 |
| Prostate cancer KEGG:hsa05215 |
| Proteasome KEGG:hsa03050 |
| Proteasome, 19S regulatory particle (PA700) KEGG:hsa_M00341 |
| Proteasome, 20S core particle KEGG:hsa_M00340 |
| Protein digestion and absorption KEGG:hsa04974 |
| Protein export KEGG:hsa03060 |
| Protein folding REACT:R-HSA-391251 |
| Protein methylation REACT:R-HSA-8876725 |
| Protein processing in endoplasmic reticulum KEGG:hsa04141 |
| Protein-protein interactions at synapses REACT:R-HSA-6794362 |
| Protein repair REACT:R-HSA-5676934 |
| Protein ubiquitination REACT:R-HSA-8852135 |
| Proteoglycans in cancer KEGG:hsa05205 |
| Proton-coupled monocarboxylate transport REACT:R-HSA-433692 |
| Proton-coupled neutral amino acid transporters REACT:R-HSA-428559 |
| Proton/oligopeptide cotransporters REACT:R-HSA-427975 |
| Proximal tubule bicarbonate reclamation KEGG:hsa04964 |
| PRPP biosynthesis, ribose 5P => PRPP KEGG:hsa_M00005 |
| PTEN Loss of Function in Cancer REACT:R-HSA-5674404 |
| PTK6 Activates STAT3 REACT:R-HSA-8849474 |
| PTK6 Down-Regulation REACT:R-HSA-8849472 |
| PTK6 Expression REACT:R-HSA-8849473 |
| PTK6 promotes HIF1A stabilization REACT:R-HSA-8857538 |
| PTK6 Regulates Cell Cycle REACT:R-HSA-8849470 |
| PTK6 Regulates Proteins Involved in RNA Processing REACT:R-HSA-8849468 |
| PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases REACT:R-HSA-8849471 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 REACT:R-HSA-8849469 |
| Purine catabolism REACT:R-HSA-74259 |
| Purine metabolism KEGG:hsa00230 |
| Purine metabolism REACT:R-HSA-73847 |
| Purine ribonucleoside monophosphate biosynthesis REACT:R-HSA-73817 |
| Purine salvage REACT:R-HSA-74217 |
| Pyrimidine biosynthesis REACT:R-HSA-500753 |
| Pyrimidine catabolism REACT:R-HSA-73621 |
| Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate KEGG:hsa_M00046 |
| Pyrimidine metabolism KEGG:hsa00240 |
| Pyrimidine metabolism REACT:R-HSA-73848 |
| Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP KEGG:hsa_M00052 |
| Pyrimidine salvage reactions REACT:R-HSA-73614 |
| Pyrophosphate hydrolysis REACT:R-HSA-71737 |
| Pyruvate metabolism KEGG:hsa00620 |
| Pyruvate metabolism REACT:R-HSA-70268 |
| Pyruvate metabolism and Citric Acid (TCA) cycle REACT:R-HSA-71406 |
| Pyruvate oxidation, pyruvate => acetyl-CoA KEGG:hsa_M00307 |
| RAB GEFs exchange GTP for GDP on RABs REACT:R-HSA-8876198 |
| RAB geranylgeranylation REACT:R-HSA-8873719 |
| RA biosynthesis pathway REACT:R-HSA-5365859 |
| RAF activation REACT:R-HSA-5673000 |
| RAF-independent MAPK1/3 activation REACT:R-HSA-112409 |
| RAF/MAP kinase cascade REACT:R-HSA-5673001 |
| Rap1 signaling pathway KEGG:hsa04015 |
| Rap1 signalling REACT:R-HSA-392517 |
| Ras activation uopn Ca2+ infux through NMDA receptor REACT:R-HSA-442982 |
| RAS signaling downstream of NF1 loss-of-function variants REACT:R-HSA-6802953 |
| Ras signaling pathway KEGG:hsa04014 |
| Reactions specific to the complex N-glycan synthesis pathway REACT:R-HSA-975578 |
| Reactions specific to the hybrid N-glycan synthesis pathway REACT:R-HSA-975574 |
| Recognition and association of DNA glycosylase with site containing an affected purine REACT:R-HSA-110330 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine REACT:R-HSA-110328 |
| Recognition of DNA damage by PCNA-containing replication complex REACT:R-HSA-110314 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks REACT:R-HSA-5693565 |
| Recruitment of mitotic centrosome proteins and complexes REACT:R-HSA-380270 |
| Recruitment of NuMA to mitotic centrosomes REACT:R-HSA-380320 |
| Recycling of bile acids and salts REACT:R-HSA-159418 |
| Recycling of eIF2:GDP REACT:R-HSA-72731 |
| Recycling pathway of L1 REACT:R-HSA-437239 |
| Reduction of cytosolic Ca++ levels REACT:R-HSA-418359 |
| Reelin signalling pathway REACT:R-HSA-8866376 |
| Regulated Necrosis REACT:R-HSA-5218859 |
| Regulated proteolysis of p75NTR REACT:R-HSA-193692 |
| Regulation by c-FLIP REACT:R-HSA-3371378 |
| Regulation by TREX1 REACT:R-HSA-3248023 |
| Regulation of actin cytoskeleton KEGG:hsa04810 |
| Regulation of actin dynamics for phagocytic cup formation REACT:R-HSA-2029482 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation REACT:R-HSA-211733 |
| Regulation of APC/C activators between G1/S and early anaphase REACT:R-HSA-176408 |
| Regulation of Apoptosis REACT:R-HSA-169911 |
| Regulation of beta-cell development REACT:R-HSA-186712 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) REACT:R-HSA-1655829 |
| Regulation of Commissural axon pathfinding by Slit and Robo REACT:R-HSA-428542 |
| Regulation of Complement cascade REACT:R-HSA-977606 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components REACT:R-HSA-446388 |
| Regulation of DNA replication REACT:R-HSA-69304 |
| Regulation of FZD by ubiquitination REACT:R-HSA-4641263 |
| Regulation of gap junction activity REACT:R-HSA-191650 |
| Regulation of gene expression by Hypoxia-inducible Factor REACT:R-HSA-1234158 |
| Regulation of gene expression in beta cells REACT:R-HSA-210745 |
| Regulation of gene expression in early pancreatic precursor cells REACT:R-HSA-210747 |
| Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells REACT:R-HSA-210746 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells REACT:R-HSA-210744 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein REACT:R-HSA-170822 |
| Regulation of HSF1-mediated heat shock response REACT:R-HSA-3371453 |
| Regulation of Hypoxia-inducible Factor (HIF) by oxygen REACT:R-HSA-1234174 |
| Regulation of IFNA signaling REACT:R-HSA-912694 |
| Regulation of IFNG signaling REACT:R-HSA-877312 |
| Regulation of innate immune responses to cytosolic DNA REACT:R-HSA-3134975 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) REACT:R-HSA-381426 |
| Regulation of insulin secretion REACT:R-HSA-422356 |
| Regulation of KIT signaling REACT:R-HSA-1433559 |
| Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) REACT:R-HSA-400206 |
| Regulation of lipolysis in adipocytes KEGG:hsa04923 |
| Regulation of mitotic cell cycle REACT:R-HSA-453276 |
| Regulation of mRNA stability by proteins that bind AU-rich elements REACT:R-HSA-450531 |
| Regulation of necroptotic cell death REACT:R-HSA-5675482 |
| Regulation of ornithine decarboxylase (ODC) REACT:R-HSA-350562 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 REACT:R-HSA-211728 |
| Regulation of PLK1 Activity at G2/M Transition REACT:R-HSA-2565942 |
| Regulation of pyruvate dehydrogenase (PDH) complex REACT:R-HSA-204174 |
| Regulation of RAS by GAPs REACT:R-HSA-5658442 |
| Regulation of signaling by CBL REACT:R-HSA-912631 |
| Regulation of signaling by NODAL REACT:R-HSA-1433617 |
| Regulation of thyroid hormone activity REACT:R-HSA-350864 |
| Regulation of TLR by endogenous ligand REACT:R-HSA-5686938 |
| Regulation of TNFR1 signaling REACT:R-HSA-5357905 |
| Regulation of TP53 Activity REACT:R-HSA-5633007 |
| Regulation of TP53 Activity through Acetylation REACT:R-HSA-6804758 |
| Regulation of TP53 Activity through Association with Co-factors REACT:R-HSA-6804759 |
| Regulation of TP53 Activity through Methylation REACT:R-HSA-6804760 |
| Regulation of TP53 Activity through Phosphorylation REACT:R-HSA-6804756 |
| Regulation of TP53 Degradation REACT:R-HSA-6804757 |
| Regulation of TP53 Expression REACT:R-HSA-6804754 |
| Regulation of TP53 Expression and Degradation REACT:R-HSA-6806003 |
| Relaxin receptors REACT:R-HSA-444821 |
| Release REACT:R-HSA-168298 |
| Release of apoptotic factors from the mitochondria REACT:R-HSA-111457 |
| Release of Hh-Np from the secreting cell REACT:R-HSA-5362798 |
| Removal of aminoterminal propeptides from gamma-carboxylated proteins REACT:R-HSA-159782 |
| Removal of licensing factors from origins REACT:R-HSA-69300 |
| Removal of the Flap Intermediate REACT:R-HSA-69166 |
| Removal of the Flap Intermediate from the C-strand REACT:R-HSA-174437 |
| Renal cell carcinoma KEGG:hsa05211 |
| Renin-angiotensin system KEGG:hsa04614 |
| Renin secretion KEGG:hsa04924 |
| Repression of WNT target genes REACT:R-HSA-4641265 |
| Reproduction REACT:R-HSA-1474165 |
| Resolution of Abasic Sites (AP sites) REACT:R-HSA-73933 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway REACT:R-HSA-110373 |
| Resolution of AP sites via the single-nucleotide replacement pathway REACT:R-HSA-110381 |
| Resolution of D-Loop Structures REACT:R-HSA-5693537 |
| Resolution of D-loop Structures through Holliday Junction Intermediates REACT:R-HSA-5693568 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) REACT:R-HSA-5693554 |
| Resolution of Sister Chromatid Cohesion REACT:R-HSA-2500257 |
| Respiratory electron transport REACT:R-HSA-611105 |
| Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. REACT:R-HSA-163200 |
| Response of Mtb to phagocytosis REACT:R-HSA-1222499 |
| Response to elevated platelet cytosolic Ca2+ REACT:R-HSA-76005 |
| Response to metal ions REACT:R-HSA-5660526 |
| Retinoid cycle disease events REACT:R-HSA-2453864 |
| Retinoid metabolism and transport REACT:R-HSA-975634 |
| Retinoid metabolism disease events REACT:R-HSA-6809583 |
| Retinol metabolism KEGG:hsa00830 |
| Retrograde endocannabinoid signaling KEGG:hsa04723 |
| Retrograde neurotrophin signalling REACT:R-HSA-177504 |
| Retrograde transport at the Trans-Golgi-Network REACT:R-HSA-6811440 |
| RET signaling REACT:R-HSA-8853659 |
| Reuptake of GABA REACT:R-HSA-888593 |
| Reversal of alkylation damage by DNA dioxygenases REACT:R-HSA-73943 |
| Reverse Transcription of HIV RNA REACT:R-HSA-162589 |
| Reversible hydration of carbon dioxide REACT:R-HSA-1475029 |
| Rev-mediated nuclear export of HIV RNA REACT:R-HSA-165054 |
| RF-C complex KEGG:hsa_M00289 |
| Rhesus glycoproteins mediate ammonium transport. REACT:R-HSA-444411 |
| Rheumatoid arthritis KEGG:hsa05323 |
| Rho GTPase cycle REACT:R-HSA-194840 |
| RHO GTPase Effectors REACT:R-HSA-195258 |
| RHO GTPases activate CIT REACT:R-HSA-5625900 |
| RHO GTPases Activate Formins REACT:R-HSA-5663220 |
| RHO GTPases activate IQGAPs REACT:R-HSA-5626467 |
| RHO GTPases activate KTN1 REACT:R-HSA-5625970 |
| RHO GTPases Activate NADPH Oxidases REACT:R-HSA-5668599 |
| RHO GTPases activate PAKs REACT:R-HSA-5627123 |
| RHO GTPases activate PKNs REACT:R-HSA-5625740 |
| RHO GTPases Activate Rhotekin and Rhophilins REACT:R-HSA-5666185 |
| RHO GTPases Activate ROCKs REACT:R-HSA-5627117 |
| RHO GTPases Activate WASPs and WAVEs REACT:R-HSA-5663213 |
| RHO GTPases regulate CFTR trafficking REACT:R-HSA-5627083 |
| Riboflavin metabolism KEGG:hsa00740 |
| Ribosomal scanning and start codon recognition REACT:R-HSA-72702 |
| Ribosome KEGG:hsa03010 |
| Ribosome biogenesis in eukaryotes KEGG:hsa03008 |
| Ribosome, eukaryotes KEGG:hsa_M00177 |
| RIG-I-like receptor signaling pathway KEGG:hsa04622 |
| RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways REACT:R-HSA-168928 |
| RIPK1-mediated regulated necrosis REACT:R-HSA-5213460 |
| RIP-mediated NFkB activation via ZBP1 REACT:R-HSA-1810476 |
| RMTs methylate histone arginines REACT:R-HSA-3214858 |
| RNA degradation KEGG:hsa03018 |
| RNA Pol II CTD phosphorylation and interaction with CE REACT:R-HSA-77075 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection REACT:R-HSA-167160 |
| RNA polymerase KEGG:hsa03020 |
| RNA Polymerase I Chain Elongation REACT:R-HSA-73777 |
| RNA polymerase I, eukaryotes KEGG:hsa_M00182 |
| RNA polymerase II, eukaryotes KEGG:hsa_M00180 |
| RNA Polymerase II HIV Promoter Escape REACT:R-HSA-167162 |
| RNA Polymerase III Abortive And Retractive Initiation REACT:R-HSA-749476 |
| RNA Polymerase III Chain Elongation REACT:R-HSA-73780 |
| RNA polymerase III, eukaryotes KEGG:hsa_M00181 |
| RNA Polymerase III Transcription REACT:R-HSA-74158 |
| RNA Polymerase III Transcription Initiation REACT:R-HSA-76046 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter REACT:R-HSA-76061 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter REACT:R-HSA-76066 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter REACT:R-HSA-76071 |
| RNA Polymerase III Transcription Termination REACT:R-HSA-73980 |
| RNA Polymerase II Pre-transcription Events REACT:R-HSA-674695 |
| RNA Polymerase II Promoter Escape REACT:R-HSA-73776 |
| RNA polymerase II transcribes snRNA genes REACT:R-HSA-6807505 |
| RNA Polymerase II Transcription REACT:R-HSA-73857 |
| RNA Polymerase II Transcription Elongation REACT:R-HSA-75955 |
| RNA Polymerase II Transcription Initiation REACT:R-HSA-75953 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance REACT:R-HSA-76042 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening REACT:R-HSA-73779 |
| RNA Polymerase II Transcription Termination REACT:R-HSA-73856 |
| RNA Polymerase I Promoter Clearance REACT:R-HSA-73854 |
| RNA Polymerase I Promoter Escape REACT:R-HSA-73772 |
| RNA Polymerase I Promoter Opening REACT:R-HSA-73728 |
| RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription REACT:R-HSA-504046 |
| RNA Polymerase I Transcription REACT:R-HSA-73864 |
| RNA Polymerase I Transcription Initiation REACT:R-HSA-73762 |
| RNA Polymerase I Transcription Termination REACT:R-HSA-73863 |
| RNA transport KEGG:hsa03013 |
| RNF mutants show enhanced WNT signaling and proliferation REACT:R-HSA-5340588 |
| Role of Abl in Robo-Slit signaling REACT:R-HSA-428890 |
| Role of LAT2/NTAL/LAB on calcium mobilization REACT:R-HSA-2730905 |
| Role of phospholipids in phagocytosis REACT:R-HSA-2029485 |
| Role of second messengers in netrin-1 signaling REACT:R-HSA-418890 |
| RORA activates gene expression REACT:R-HSA-1368082 |
| ROS, RNS production in phagocytes REACT:R-HSA-1222556 |
| RPA complex KEGG:hsa_M00288 |
| RPIA deficiency: failed conversion of R5P to RU5P REACT:R-HSA-5659996 |
| RPIA deficiency: failed conversion of RU5P to R5P REACT:R-HSA-6791461 |
| rRNA modification in the mitochondrion REACT:R-HSA-6793080 |
| rRNA modification in the nucleus and cytosol REACT:R-HSA-6790901 |
| rRNA processing REACT:R-HSA-72312 |
| rRNA processing in the mitochondrion REACT:R-HSA-8868766 |
| rRNA processing in the nucleus and cytosol REACT:R-HSA-8868773 |
| RSK activation REACT:R-HSA-444257 |
| S33 mutants of beta-catenin aren't phosphorylated REACT:R-HSA-5358747 |
| S37 mutants of beta-catenin aren't phosphorylated REACT:R-HSA-5358749 |
| S45 mutants of beta-catenin aren't phosphorylated REACT:R-HSA-5358751 |
| Salivary secretion KEGG:hsa04970 |
| Salmonella infection KEGG:hsa05132 |
| SALM protein interactions at the synapses REACT:R-HSA-8849932 |
| Scavenging by Class A Receptors REACT:R-HSA-3000480 |
| Scavenging by Class B Receptors REACT:R-HSA-3000471 |
| Scavenging by Class F Receptors REACT:R-HSA-3000484 |
| Scavenging by Class H Receptors REACT:R-HSA-3000497 |
| Scavenging of heme from plasma REACT:R-HSA-2168880 |
| SCF-beta-TrCP mediated degradation of Emi1 REACT:R-HSA-174113 |
| SCF-BTRC complex KEGG:hsa_M00380 |
| SCF-FBS complex KEGG:hsa_M00382 |
| SCF-FBW7 complex KEGG:hsa_M00387 |
| SCF-SKP2 complex KEGG:hsa_M00381 |
| SCF(Skp2)-mediated degradation of p27/p21 REACT:R-HSA-187577 |
| Sec61 complex KEGG:hsa_M00401 |
| Selenoamino acid metabolism REACT:R-HSA-2408522 |
| Selenocompound metabolism KEGG:hsa00450 |
| Selenocysteine synthesis REACT:R-HSA-2408557 |
| Sema3A PAK dependent Axon repulsion REACT:R-HSA-399954 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion REACT:R-HSA-399955 |
| Sema4D induced cell migration and growth-cone collapse REACT:R-HSA-416572 |
| Sema4D in semaphorin signaling REACT:R-HSA-400685 |
| Sema4D mediated inhibition of cell attachment and migration REACT:R-HSA-416550 |
| Semaphorin interactions REACT:R-HSA-373755 |
| SeMet incorporation into proteins REACT:R-HSA-2408517 |
| Senescence-Associated Secretory Phenotype (SASP) REACT:R-HSA-2559582 |
| Sensing of DNA Double Strand Breaks REACT:R-HSA-5693548 |
| Separation of Sister Chromatids REACT:R-HSA-2467813 |
| Serine biosynthesis REACT:R-HSA-977347 |
| Serine biosynthesis, glycerate-3P => serine KEGG:hsa_M00020 |
| Serotonergic synapse KEGG:hsa04726 |
| Serotonin and melatonin biosynthesis REACT:R-HSA-209931 |
| Serotonin clearance from the synaptic cleft REACT:R-HSA-380615 |
| Serotonin Neurotransmitter Release Cycle REACT:R-HSA-181429 |
| Serotonin receptors REACT:R-HSA-390666 |
| Severe congenital neutropenia type 4 (G6PC3) REACT:R-HSA-3282872 |
| SHC1 events in EGFR signaling REACT:R-HSA-180336 |
| SHC1 events in ERBB2 signaling REACT:R-HSA-1250196 |
| SHC1 events in ERBB4 signaling REACT:R-HSA-1250347 |
| SHC-mediated cascade:FGFR1 REACT:R-HSA-5654688 |
| SHC-mediated cascade:FGFR2 REACT:R-HSA-5654699 |
| SHC-mediated cascade:FGFR3 REACT:R-HSA-5654704 |
| SHC-mediated cascade:FGFR4 REACT:R-HSA-5654719 |
| SHC-related events triggered by IGF1R REACT:R-HSA-2428933 |
| Shelterin complex KEGG:hsa_M00424 |
| Shigellosis KEGG:hsa05131 |
| Sialic acid metabolism REACT:R-HSA-4085001 |
| Signal amplification REACT:R-HSA-392518 |
| Signal attenuation REACT:R-HSA-74749 |
| Signaling by activated point mutants of FGFR1 REACT:R-HSA-1839122 |
| Signaling by activated point mutants of FGFR3 REACT:R-HSA-1839130 |
| Signaling by Activin REACT:R-HSA-1502540 |
| Signaling by BMP REACT:R-HSA-201451 |
| Signaling by BRAF and RAF fusions REACT:R-HSA-6802952 |
| Signaling by cytosolic FGFR1 fusion mutants REACT:R-HSA-1839117 |
| Signaling by EGFR REACT:R-HSA-177929 |
| Signaling by EGFR in Cancer REACT:R-HSA-1643713 |
| Signaling by EGFRvIII in Cancer REACT:R-HSA-5637812 |
| Signaling by ERBB2 REACT:R-HSA-1227986 |
| Signaling by ERBB4 REACT:R-HSA-1236394 |
| Signaling by FGFR REACT:R-HSA-190236 |
| Signaling by FGFR1 REACT:R-HSA-5654736 |
| Signaling by FGFR1 amplification mutants REACT:R-HSA-1839120 |
| Signaling by FGFR1 in disease REACT:R-HSA-5655302 |
| Signaling by FGFR2 REACT:R-HSA-5654738 |
| Signaling by FGFR2 amplification mutants REACT:R-HSA-2023837 |
| Signaling by FGFR2 fusions REACT:R-HSA-8853333 |
| Signaling by FGFR2 IIIa TM REACT:R-HSA-8851708 |
| Signaling by FGFR2 in disease REACT:R-HSA-5655253 |
| Signaling by FGFR3 REACT:R-HSA-5654741 |
| Signaling by FGFR3 fusions in cancer REACT:R-HSA-8853334 |
| Signaling by FGFR3 in disease REACT:R-HSA-5655332 |
| Signaling by FGFR3 point mutants in cancer REACT:R-HSA-8853338 |
| Signaling by FGFR4 REACT:R-HSA-5654743 |
| Signaling by FGFR4 in disease REACT:R-HSA-5655291 |
| Signaling by FGFR in disease REACT:R-HSA-1226099 |
| Signaling by GPCR REACT:R-HSA-372790 |
| Signaling by Hedgehog REACT:R-HSA-5358351 |
| Signaling by high-kinase activity BRAF mutants REACT:R-HSA-6802948 |
| Signaling by Hippo REACT:R-HSA-2028269 |
| Signaling by Insulin receptor REACT:R-HSA-74752 |
| Signaling by Interleukins REACT:R-HSA-449147 |
| Signaling by Leptin REACT:R-HSA-2586552 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer REACT:R-HSA-5637815 |
| Signaling by MET REACT:R-HSA-6806834 |
| Signaling by moderate kinase activity BRAF mutants REACT:R-HSA-6802946 |
| Signaling by MST1 REACT:R-HSA-8852405 |
| Signaling by NODAL REACT:R-HSA-1181150 |
| Signaling by NOTCH REACT:R-HSA-157118 |
| Signaling by NOTCH1 REACT:R-HSA-1980143 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer REACT:R-HSA-2691230 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer REACT:R-HSA-2894858 |
| Signaling by NOTCH1 in Cancer REACT:R-HSA-2644603 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer REACT:R-HSA-2644602 |
| Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant REACT:R-HSA-2660825 |
| Signaling by NOTCH2 REACT:R-HSA-1980145 |
| Signaling by NOTCH3 REACT:R-HSA-1980148 |
| Signaling by NOTCH4 REACT:R-HSA-1980150 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer REACT:R-HSA-5638302 |
| Signaling by PDGF REACT:R-HSA-186797 |
| Signaling by plasma membrane FGFR1 fusions REACT:R-HSA-8853336 |
| Signaling by PTK6 REACT:R-HSA-8848021 |
| Signaling by RAS mutants REACT:R-HSA-6802949 |
| Signaling by Retinoic Acid REACT:R-HSA-5362517 |
| Signaling by Rho GTPases REACT:R-HSA-194315 |
| Signaling by Robo receptor REACT:R-HSA-376176 |
| Signaling by SCF-KIT REACT:R-HSA-1433557 |
| Signaling by TGF-beta Receptor Complex REACT:R-HSA-170834 |
| Signaling by TGF-beta Receptor Complex in Cancer REACT:R-HSA-3304351 |
| Signaling by the B Cell Receptor (BCR) REACT:R-HSA-983705 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) REACT:R-HSA-2404192 |
| Signaling by VEGF REACT:R-HSA-194138 |
| Signaling by Wnt REACT:R-HSA-195721 |
| Signaling by WNT in cancer REACT:R-HSA-4791275 |
| Signaling pathways regulating pluripotency of stem cells KEGG:hsa04550 |
| Signalling by NGF REACT:R-HSA-166520 |
| Signalling to ERK5 REACT:R-HSA-198765 |
| Signalling to ERKs REACT:R-HSA-187687 |
| Signalling to p38 via RIT and RIN REACT:R-HSA-187706 |
| Signalling to RAS REACT:R-HSA-167044 |
| Signalling to STAT3 REACT:R-HSA-198745 |
| Signal regulatory protein (SIRP) family interactions REACT:R-HSA-391160 |
| Signal Transduction REACT:R-HSA-162582 |
| Signal transduction by L1 REACT:R-HSA-445144 |
| SIRT1 negatively regulates rRNA Expression REACT:R-HSA-427359 |
| Ski complex KEGG:hsa_M00392 |
| SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs REACT:R-HSA-77588 |
| SLBP independent Processing of Histone Pre-mRNAs REACT:R-HSA-111367 |
| SLC-mediated transmembrane transport REACT:R-HSA-425407 |
| SLC transporter disorders REACT:R-HSA-5619102 |
| SMAC binds to IAPs REACT:R-HSA-111463 |
| SMAC-mediated apoptotic response REACT:R-HSA-111469 |
| SMAC-mediated dissociation of IAP:caspase complexes REACT:R-HSA-111464 |
| SMAD2/3 MH2 Domain Mutants in Cancer REACT:R-HSA-3315487 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer REACT:R-HSA-3304356 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription REACT:R-HSA-2173796 |
| SMAD4 MH2 Domain Mutants in Cancer REACT:R-HSA-3311021 |
| Small cell lung cancer KEGG:hsa05222 |
| Small interfering RNA (siRNA) biogenesis REACT:R-HSA-426486 |
| Sm core complex KEGG:hsa_M00398 |
| Smooth Muscle Contraction REACT:R-HSA-445355 |
| SNARE interactions in vesicular transport KEGG:hsa04130 |
| snRNP Assembly REACT:R-HSA-191859 |
| Sodium/Calcium exchangers REACT:R-HSA-425561 |
| Sodium-coupled phosphate cotransporters REACT:R-HSA-427652 |
| Sodium-coupled sulphate, di- and tri-carboxylate transporters REACT:R-HSA-433137 |
| Sodium/Proton exchangers REACT:R-HSA-425986 |
| SOS-mediated signalling REACT:R-HSA-112412 |
| Sperm Motility And Taxes REACT:R-HSA-1300642 |
| Sperm:Oocyte Membrane Binding REACT:R-HSA-1300652 |
| S Phase REACT:R-HSA-69242 |
| Sphingolipid de novo biosynthesis REACT:R-HSA-1660661 |
| Sphingolipid metabolism KEGG:hsa00600 |
| Sphingolipid metabolism REACT:R-HSA-428157 |
| Sphingolipid signaling pathway KEGG:hsa04071 |
| Sphingosine biosynthesis KEGG:hsa_M00099 |
| Sphingosine degradation KEGG:hsa_M00100 |
| Spliceosome KEGG:hsa03040 |
| Spliceosome, 35S U5-snRNP KEGG:hsa_M00355 |
| Spliceosome, Prp19/CDC5L complex KEGG:hsa_M00353 |
| Spliceosome, U1-snRNP KEGG:hsa_M00351 |
| Spliceosome, U2-snRNP KEGG:hsa_M00352 |
| Spliceosome, U4/U6.U5 tri-snRNP KEGG:hsa_M00354 |
| Spry regulation of FGF signaling REACT:R-HSA-1295596 |
| SRP-dependent cotranslational protein targeting to membrane REACT:R-HSA-1799339 |
| Stabilization of p53 REACT:R-HSA-69541 |
| Staphylococcus aureus infection KEGG:hsa05150 |
| Starch and sucrose metabolism KEGG:hsa00500 |
| STAT6-mediated induction of chemokines REACT:R-HSA-3249367 |
| Steroid biosynthesis KEGG:hsa00100 |
| Steroid hormone biosynthesis KEGG:hsa00140 |
| Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone KEGG:hsa_M00107 |
| Sterols are 12-hydroxylated by CYP8B1 REACT:R-HSA-211994 |
| Stimulation of the cell death response by PAK-2p34 REACT:R-HSA-211736 |
| Stimuli-sensing channels REACT:R-HSA-2672351 |
| STING mediated induction of host immune responses REACT:R-HSA-1834941 |
| Striated Muscle Contraction REACT:R-HSA-390522 |
| Succinate dehydrogenase (ubiquinone) KEGG:hsa_M00148 |
| Sulfide oxidation to sulfate REACT:R-HSA-1614517 |
| Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid KEGG:hsa_M00067 |
| Sulfur amino acid metabolism REACT:R-HSA-1614635 |
| Sulfur metabolism KEGG:hsa00920 |
| Sulfur relay system KEGG:hsa04122 |
| SUMO E3 ligases SUMOylate target proteins REACT:R-HSA-3108232 |
| SUMO is conjugated to E1 (UBA2:SAE1) REACT:R-HSA-3065676 |
| SUMO is proteolytically processed REACT:R-HSA-3065679 |
| SUMO is transferred from E1 to E2 (UBE2I, UBC9) REACT:R-HSA-3065678 |
| SUMOylation REACT:R-HSA-2990846 |
| SUMOylation of chromatin organization proteins REACT:R-HSA-4551638 |
| SUMOylation of DNA damage response and repair proteins REACT:R-HSA-3108214 |
| SUMOylation of DNA replication proteins REACT:R-HSA-4615885 |
| SUMOylation of RNA binding proteins REACT:R-HSA-4570464 |
| SUMOylation of transcription factors REACT:R-HSA-3232118 |
| Surfactant metabolism REACT:R-HSA-5683826 |
| Survival motor neuron (SMN) complex KEGG:hsa_M00426 |
| Switching of origins to a post-replicative state REACT:R-HSA-69052 |
| Synaptic vesicle cycle KEGG:hsa04721 |
| Syndecan interactions REACT:R-HSA-3000170 |
| Synthesis and degradation of ketone bodies KEGG:hsa00072 |
| Synthesis and interconversion of nucleotide di- and triphosphates REACT:R-HSA-499943 |
| Synthesis and processing of ENV and VPU REACT:R-HSA-171286 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins REACT:R-HSA-174495 |
| Synthesis of 12-eicosatetraenoic acid derivatives REACT:R-HSA-2142712 |
| Synthesis of 15-eicosatetraenoic acid derivatives REACT:R-HSA-2142770 |
| Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) REACT:R-HSA-2142816 |
| Synthesis of 5-eicosatetraenoic acids REACT:R-HSA-2142688 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes REACT:R-HSA-8866652 |
| Synthesis of bile acids and bile salts REACT:R-HSA-192105 |
| Synthesis of bile acids and bile salts via 24-hydroxycholesterol REACT:R-HSA-193775 |
| Synthesis of bile acids and bile salts via 27-hydroxycholesterol REACT:R-HSA-193807 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol REACT:R-HSA-193368 |
| Synthesis of BMP REACT:R-HSA-1483171 |
| Synthesis of CL REACT:R-HSA-1483076 |
| Synthesis of diphthamide-EEF2 REACT:R-HSA-5358493 |
| Synthesis of DNA REACT:R-HSA-69239 |
| Synthesis of Dolichyl-phosphate REACT:R-HSA-446199 |
| Synthesis of dolichyl-phosphate-glucose REACT:R-HSA-480985 |
| Synthesis of dolichyl-phosphate mannose REACT:R-HSA-162699 |
| Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) REACT:R-HSA-2142670 |
| Synthesis of GDP-mannose REACT:R-HSA-446205 |
| Synthesis of glycosylphosphatidylinositol (GPI) REACT:R-HSA-162710 |
| Synthesis of Hepoxilins (HX) and Trioxilins (TrX) REACT:R-HSA-2142696 |
| Synthesis of IP2, IP, and Ins in the cytosol REACT:R-HSA-1855183 |
| Synthesis of IP3 and IP4 in the cytosol REACT:R-HSA-1855204 |
| Synthesis of IPs in the ER lumen REACT:R-HSA-1855231 |
| Synthesis of IPs in the nucleus REACT:R-HSA-1855191 |
| Synthesis of Ketone Bodies REACT:R-HSA-77111 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) REACT:R-HSA-2142691 |
| Synthesis of Lipoxins (LX) REACT:R-HSA-2142700 |
| Synthesis of PA REACT:R-HSA-1483166 |
| Synthesis of PC REACT:R-HSA-1483191 |
| Synthesis of PE REACT:R-HSA-1483213 |
| Synthesis of PG REACT:R-HSA-1483148 |
| Synthesis of PI REACT:R-HSA-1483226 |
| Synthesis of PIPs at the early endosome membrane REACT:R-HSA-1660516 |
| Synthesis of PIPs at the ER membrane REACT:R-HSA-1483248 |
| Synthesis of PIPs at the Golgi membrane REACT:R-HSA-1660514 |
| Synthesis of PIPs at the late endosome membrane REACT:R-HSA-1660517 |
| Synthesis of PIPs at the plasma membrane REACT:R-HSA-1660499 |
| Synthesis of PIPs in the nucleus REACT:R-HSA-8847453 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) REACT:R-HSA-2162123 |
| Synthesis of PS REACT:R-HSA-1483101 |
| Synthesis of pyrophosphates in the cytosol REACT:R-HSA-1855167 |
| Synthesis of substrates in N-glycan biosythesis REACT:R-HSA-446219 |
| Synthesis of UDP-N-acetyl-glucosamine REACT:R-HSA-446210 |
| Synthesis of very long-chain fatty acyl-CoAs REACT:R-HSA-75876 |
| Synthesis of wybutosine at G37 of tRNA(Phe) REACT:R-HSA-6782861 |
| Synthesis, secretion, and deacylation of Ghrelin REACT:R-HSA-422085 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) REACT:R-HSA-381771 |
| Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) REACT:R-HSA-400511 |
| Systemic lupus erythematosus KEGG:hsa05322 |
| t(4;14) translocations of FGFR3 REACT:R-HSA-2033515 |
| T41 mutants of beta-catenin aren't phosphorylated REACT:R-HSA-5358752 |
| Tachykinin receptors bind tachykinins REACT:R-HSA-380095 |
| TAK1 activates NFkB by phosphorylation and activation of IKKs complex REACT:R-HSA-445989 |
| TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P REACT:R-HSA-6791462 |
| TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P REACT:R-HSA-6791055 |
| Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) REACT:R-HSA-1299308 |
| Tandem pore domain halothane-inhibited K+ channel (THIK) REACT:R-HSA-1299287 |
| Tandem pore domain potassium channels REACT:R-HSA-1296346 |
| Taste transduction KEGG:hsa04742 |
| Tat-mediated elongation of the HIV-1 transcript REACT:R-HSA-167246 |
| Tat-mediated HIV elongation arrest and recovery REACT:R-HSA-167243 |
| Taurine and hypotaurine metabolism KEGG:hsa00430 |
| TBC/RABGAPs REACT:R-HSA-8854214 |
| T cell receptor signaling pathway KEGG:hsa04660 |
| TCF7L2 mutants don't bind CTBP REACT:R-HSA-5339700 |
| TCF dependent signaling in response to WNT REACT:R-HSA-201681 |
| TCR signaling REACT:R-HSA-202403 |
| Telomere C-strand (Lagging Strand) Synthesis REACT:R-HSA-174417 |
| Telomere C-strand synthesis initiation REACT:R-HSA-174430 |
| Telomere Extension By Telomerase REACT:R-HSA-171319 |
| Telomere Maintenance REACT:R-HSA-157579 |
| Terminal pathway of complement REACT:R-HSA-166665 |
| Termination of O-glycan biosynthesis REACT:R-HSA-977068 |
| Termination of translesion DNA synthesis REACT:R-HSA-5656169 |
| Terpenoid backbone biosynthesis KEGG:hsa00900 |
| TET1,2,3 and TDG demethylate DNA REACT:R-HSA-5221030 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation REACT:R-HSA-1474151 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation REACT:R-HSA-8869496 |
| TFAP2 (AP-2) family regulates transcription of cell cycle factors REACT:R-HSA-8866911 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors REACT:R-HSA-8866910 |
| TFAP2 (AP-2) family regulates transcription of other transcription factors REACT:R-HSA-8866906 |
| TGF-beta receptor signaling activates SMADs REACT:R-HSA-2173789 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) REACT:R-HSA-2173791 |
| TGF-beta signaling KEGG:hsa_M00680 |
| TGF-beta signaling pathway KEGG:hsa04350 |
| TGFBR1 KD Mutants in Cancer REACT:R-HSA-3656532 |
| TGFBR1 LBD Mutants in Cancer REACT:R-HSA-3656535 |
| TGFBR2 Kinase Domain Mutants in Cancer REACT:R-HSA-3645790 |
| TGFBR2 MSI Frameshift Mutants in Cancer REACT:R-HSA-3642279 |
| Th17 cell differentiation KEGG:hsa04659 |
| Th1 and Th2 cell differentiation KEGG:hsa04658 |
| THC complex KEGG:hsa_M00405 |
| The activation of arylsulfatases REACT:R-HSA-1663150 |
| The AIM2 inflammasome REACT:R-HSA-844615 |
| The canonical retinoid cycle in rods (twilight vision) REACT:R-HSA-2453902 |
| The citric acid (TCA) cycle and respiratory electron transport REACT:R-HSA-1428517 |
| The fatty acid cycling model REACT:R-HSA-167826 |
| The IPAF inflammasome REACT:R-HSA-844623 |
| The NLRP1 inflammasome REACT:R-HSA-844455 |
| The NLRP3 inflammasome REACT:R-HSA-844456 |
| The phototransduction cascade REACT:R-HSA-2514856 |
| The proton buffering model REACT:R-HSA-167827 |
| The retinoid cycle in cones (daylight vision) REACT:R-HSA-2187335 |
| The role of GTSE1 in G2/M progression after G2 checkpoint REACT:R-HSA-8852276 |
| The role of Nef in HIV-1 replication and disease pathogenesis REACT:R-HSA-164952 |
| Thiamine metabolism KEGG:hsa00730 |
| Threonine catabolism REACT:R-HSA-8849175 |
| Thrombin signalling through proteinase activated receptors (PARs) REACT:R-HSA-456926 |
| Thromboxane signalling through TP receptor REACT:R-HSA-428930 |
| Thyroid cancer KEGG:hsa05216 |
| Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine KEGG:hsa_M00043 |
| Thyroid hormone signaling pathway KEGG:hsa04919 |
| Thyroid hormone synthesis KEGG:hsa04918 |
| Thyroxine biosynthesis REACT:R-HSA-209968 |
| TICAM1 deficiency - HSE REACT:R-HSA-5602566 |
| Tie2 Signaling REACT:R-HSA-210993 |
| Tight junction KEGG:hsa04530 |
| Tight junction interactions REACT:R-HSA-420029 |
| TLR3 deficiency - HSE REACT:R-HSA-5602410 |
| TNFR1-induced NFkappaB signaling pathway REACT:R-HSA-5357956 |
| TNFR1-induced proapoptotic signaling REACT:R-HSA-5357786 |
| TNFR1-mediated ceramide production REACT:R-HSA-5626978 |
| TNFR2 non-canonical NF-kB pathway REACT:R-HSA-5668541 |
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway REACT:R-HSA-5676594 |
| TNFs bind their physiological receptors REACT:R-HSA-5669034 |
| TNF signaling REACT:R-HSA-75893 |
| TNF signaling pathway KEGG:hsa04668 |
| Tolerance by Mtb to nitric oxide produced by macrophages REACT:R-HSA-1222538 |
| Tolerance of reactive oxygen produced by macrophages REACT:R-HSA-1222387 |
| Toll Like Receptor 10 (TLR10) Cascade REACT:R-HSA-168142 |
| Toll Like Receptor 2 (TLR2) Cascade REACT:R-HSA-181438 |
| Toll Like Receptor 3 (TLR3) Cascade REACT:R-HSA-168164 |
| Toll Like Receptor 4 (TLR4) Cascade REACT:R-HSA-166016 |
| Toll Like Receptor 5 (TLR5) Cascade REACT:R-HSA-168176 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade REACT:R-HSA-168181 |
| Toll Like Receptor 9 (TLR9) Cascade REACT:R-HSA-168138 |
| Toll-Like Receptors Cascades REACT:R-HSA-168898 |
| Toll-like receptor signaling KEGG:hsa_M00686 |
| Toll-like receptor signaling pathway KEGG:hsa04620 |
| Toll Like Receptor TLR1:TLR2 Cascade REACT:R-HSA-168179 |
| Toll Like Receptor TLR6:TLR2 Cascade REACT:R-HSA-168188 |
| Toxicity of botulinum toxin type A (BoNT/A) REACT:R-HSA-5250968 |
| Toxicity of botulinum toxin type B (BoNT/B) REACT:R-HSA-5250958 |
| Toxicity of botulinum toxin type C (BoNT/C) REACT:R-HSA-5250971 |
| Toxicity of botulinum toxin type D (BoNT/D) REACT:R-HSA-5250955 |
| Toxicity of botulinum toxin type E (BoNT/E) REACT:R-HSA-5250992 |
| Toxicity of botulinum toxin type F (BoNT/F) REACT:R-HSA-5250981 |
| Toxicity of botulinum toxin type G (BoNT/G) REACT:R-HSA-5250989 |
| Toxicity of tetanus toxin (TeNT) REACT:R-HSA-5250982 |
| Toxoplasmosis KEGG:hsa05145 |
| TP53 Regulates Metabolic Genes REACT:R-HSA-5628897 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain REACT:R-HSA-6804115 |
| TP53 Regulates Transcription of Caspase Activators and Caspases REACT:R-HSA-6803207 |
| TP53 Regulates Transcription of Cell Cycle Genes REACT:R-HSA-6791312 |
| TP53 Regulates Transcription of Cell Death Genes REACT:R-HSA-5633008 |
| TP53 Regulates Transcription of Death Receptors and Ligands REACT:R-HSA-6803211 |
| TP53 Regulates Transcription of DNA Repair Genes REACT:R-HSA-6796648 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release REACT:R-HSA-6803204 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest REACT:R-HSA-6804116 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest REACT:R-HSA-6804114 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain REACT:R-HSA-6803205 |
| TRAF3 deficiency - HSE REACT:R-HSA-5602571 |
| TRAF3-dependent IRF activation pathway REACT:R-HSA-918233 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation REACT:R-HSA-975138 |
| TRAF6 mediated induction of TAK1 complex REACT:R-HSA-937072 |
| TRAF6 mediated IRF7 activation REACT:R-HSA-933541 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling REACT:R-HSA-975110 |
| TRAF6 mediated NF-kB activation REACT:R-HSA-933542 |
| Trafficking and processing of endosomal TLR REACT:R-HSA-1679131 |
| Trafficking of AMPA receptors REACT:R-HSA-399719 |
| Trafficking of dietary sterols REACT:R-HSA-265473 |
| Trafficking of GluR2-containing AMPA receptors REACT:R-HSA-416993 |
| Trafficking of myristoylated proteins to the cilium REACT:R-HSA-5624138 |
| TRAIL signaling REACT:R-HSA-75158 |
| TRAMP complex KEGG:hsa_M00393 |
| Transcriptional activation of cell cycle inhibitor p21 REACT:R-HSA-69895 |
| Transcriptional activation of mitochondrial biogenesis REACT:R-HSA-2151201 |
| Transcriptional activation of p53 responsive genes REACT:R-HSA-69560 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer REACT:R-HSA-2173793 |
| Transcriptional misregulation in cancer KEGG:hsa05202 |
| Transcriptional regulation by small RNAs REACT:R-HSA-5578749 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors REACT:R-HSA-8864260 |
| Transcriptional Regulation by TP53 REACT:R-HSA-3700989 |
| Transcriptional regulation of pluripotent stem cells REACT:R-HSA-452723 |
| Transcriptional regulation of white adipocyte differentiation REACT:R-HSA-381340 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) REACT:R-HSA-6781827 |
| Transcription from mitochondrial promoters REACT:R-HSA-75944 |
| Transcription of the HIV genome REACT:R-HSA-167172 |
| Transfer of LPS from LBP carrier to CD14 REACT:R-HSA-166020 |
| Transferrin endocytosis and recycling REACT:R-HSA-917977 |
| trans-Golgi Network Vesicle Budding REACT:R-HSA-199992 |
| Translation REACT:R-HSA-72766 |
| Translation initiation complex formation REACT:R-HSA-72649 |
| Translesion Synthesis by POLH REACT:R-HSA-110320 |
| Translesion synthesis by POLI REACT:R-HSA-5656121 |
| Translesion synthesis by POLK REACT:R-HSA-5655862 |
| Translesion synthesis by REV1 REACT:R-HSA-110312 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template REACT:R-HSA-110313 |
| Translocation of GLUT4 to the plasma membrane REACT:R-HSA-1445148 |
| Translocation of ZAP-70 to Immunological synapse REACT:R-HSA-202430 |
| Translocon-associated protein (TRAP) complex KEGG:hsa_M00402 |
| Transmembrane transport of small molecules REACT:R-HSA-382551 |
| Transmission across Chemical Synapses REACT:R-HSA-112315 |
| Transmission across Electrical Synapses REACT:R-HSA-112307 |
| Transport and synthesis of PAPS REACT:R-HSA-174362 |
| Transport of connexins along the secretory pathway REACT:R-HSA-190827 |
| Transport of connexons to the plasma membrane REACT:R-HSA-190872 |
| Transport of fatty acids REACT:R-HSA-804914 |
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus REACT:R-HSA-159763 |
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds REACT:R-HSA-425366 |
| Transport of glycerol from adipocytes to the liver by Aquaporins REACT:R-HSA-432030 |
| Transport of HA trimer, NA tetramer and M2 tetramer from the endoplasmic reticulum to the Golgi Apparatus REACT:R-HSA-168874 |
| Transport of inorganic cations/anions and amino acids/oligopeptides REACT:R-HSA-425393 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript REACT:R-HSA-159236 |
| Transport of Mature mRNA Derived from an Intronless Transcript REACT:R-HSA-159231 |
| Transport of Mature mRNAs Derived from Intronless Transcripts REACT:R-HSA-159234 |
| Transport of Mature Transcript to Cytoplasm REACT:R-HSA-72202 |
| Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane REACT:R-HSA-83936 |
| Transport of nucleotide sugars REACT:R-HSA-727802 |
| Transport of organic anions REACT:R-HSA-879518 |
| Transport of Ribonucleoproteins into the Host Nucleus REACT:R-HSA-168271 |
| Transport of the SLBP Dependant Mature mRNA REACT:R-HSA-159230 |
| Transport of the SLBP independent Mature mRNA REACT:R-HSA-159227 |
| Transport of vitamins, nucleosides, and related molecules REACT:R-HSA-425397 |
| Transport to the Golgi and subsequent modification REACT:R-HSA-948021 |
| TREX complex KEGG:hsa_M00406 |
| Triacylglycerol biosynthesis KEGG:hsa_M00089 |
| TRIF-mediated programmed cell death REACT:R-HSA-2562578 |
| TRIF-mediated TLR3/TLR4 signaling REACT:R-HSA-937061 |
| Triglyceride Biosynthesis REACT:R-HSA-75109 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA REACT:R-HSA-450513 |
| TRKA activation by NGF REACT:R-HSA-187042 |
| tRNA Aminoacylation REACT:R-HSA-379724 |
| tRNA modification in the mitochondrion REACT:R-HSA-6787450 |
| tRNA modification in the nucleus and cytosol REACT:R-HSA-6782315 |
| tRNA processing REACT:R-HSA-72306 |
| tRNA processing in the mitochondrion REACT:R-HSA-6785470 |
| tRNA processing in the nucleus REACT:R-HSA-6784531 |
| TRP channels REACT:R-HSA-3295583 |
| truncated APC mutants destabilize the destruction complex REACT:R-HSA-4839744 |
| Truncations of AMER1 destabilize the destruction complex REACT:R-HSA-5467348 |
| Tryptophan catabolism REACT:R-HSA-71240 |
| Tryptophan metabolism KEGG:hsa00380 |
| Tuberculosis KEGG:hsa05152 |
| TWIK-related alkaline pH activated K+ channel (TALK) REACT:R-HSA-1299361 |
| TWIK related potassium channel (TREK) REACT:R-HSA-1299503 |
| TWIK-related spinal cord K+ channel (TRESK) REACT:R-HSA-1299344 |
| TWIK-releated acid-sensitive K+ channel (TASK) REACT:R-HSA-1299316 |
| Type I diabetes mellitus KEGG:hsa04940 |
| Type I hemidesmosome assembly REACT:R-HSA-446107 |
| Type II diabetes mellitus KEGG:hsa04930 |
| Type II Na+/Pi cotransporters REACT:R-HSA-427589 |
| Tyrosine degradation, tyrosine => homogentisate KEGG:hsa_M00044 |
| Tyrosine metabolism KEGG:hsa00350 |
| Ubiquinol biosynthesis REACT:R-HSA-2142789 |
| Ubiquinone and other terpenoid-quinone biosynthesis KEGG:hsa00130 |
| Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone KEGG:hsa_M00128 |
| Ubiquitin-dependent degradation of Cyclin D REACT:R-HSA-75815 |
| Ubiquitin-dependent degradation of Cyclin D1 REACT:R-HSA-69229 |
| Ubiquitin Mediated Degradation of Phosphorylated Cdc25A REACT:R-HSA-69601 |
| Ubiquitin mediated proteolysis KEGG:hsa04120 |
| Ub-specific processing proteases REACT:R-HSA-5689880 |
| UCH proteinases REACT:R-HSA-5689603 |
| Unblocking of NMDA receptor, glutamate binding and activation REACT:R-HSA-438066 |
| UNC93B1 deficiency - HSE REACT:R-HSA-5602415 |
| Uncoating of the HIV Virion REACT:R-HSA-162585 |
| Uncoating of the Influenza Virion REACT:R-HSA-168336 |
| Unfolded Protein Response (UPR) REACT:R-HSA-381119 |
| Unwinding of DNA REACT:R-HSA-176974 |
| Uptake and actions of bacterial toxins REACT:R-HSA-5339562 |
| Uptake and function of anthrax toxins REACT:R-HSA-5210891 |
| Uptake and function of diphtheria toxin REACT:R-HSA-5336415 |
| Urea cycle KEGG:hsa_M00029 |
| Urea cycle REACT:R-HSA-70635 |
| Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP KEGG:hsa_M00051 |
| Utilization of Ketone Bodies REACT:R-HSA-77108 |
| Valine, leucine and isoleucine biosynthesis KEGG:hsa00290 |
| Valine, leucine and isoleucine degradation KEGG:hsa00280 |
| Variant SLC6A14 may confer susceptibility towards obesity REACT:R-HSA-5619094 |
| Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) REACT:R-HSA-5619101 |
| Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) REACT:R-HSA-5660686 |
| Vascular smooth muscle contraction KEGG:hsa04270 |
| Vasopressin-like receptors REACT:R-HSA-388479 |
| Vasopressin-regulated water reabsorption KEGG:hsa04962 |
| Vasopressin regulates renal water homeostasis via Aquaporins REACT:R-HSA-432040 |
| VEGFA-VEGFR2 Pathway REACT:R-HSA-4420097 |
| VEGF binds to VEGFR leading to receptor dimerization REACT:R-HSA-195399 |
| VEGF ligand-receptor interactions REACT:R-HSA-194313 |
| VEGFR2 mediated cell proliferation REACT:R-HSA-5218921 |
| VEGFR2 mediated vascular permeability REACT:R-HSA-5218920 |
| VEGF signaling pathway KEGG:hsa04370 |
| Vesicle-mediated transport REACT:R-HSA-5653656 |
| Vibrio cholerae infection KEGG:hsa05110 |
| Vif-mediated degradation of APOBEC3G REACT:R-HSA-180585 |
| Viral carcinogenesis KEGG:hsa05203 |
| Viral Messenger RNA Synthesis REACT:R-HSA-168325 |
| Viral mRNA Translation REACT:R-HSA-192823 |
| Viral myocarditis KEGG:hsa05416 |
| Viral RNP Complexes in the Host Cell Nucleus REACT:R-HSA-168330 |
| Virus Assembly and Release REACT:R-HSA-168268 |
| Visual phototransduction REACT:R-HSA-2187338 |
| Vitamin B1 (thiamin) metabolism REACT:R-HSA-196819 |
| Vitamin B2 (riboflavin) metabolism REACT:R-HSA-196843 |
| Vitamin B5 (pantothenate) metabolism REACT:R-HSA-199220 |
| Vitamin B6 metabolism KEGG:hsa00750 |
| Vitamin C (ascorbate) metabolism REACT:R-HSA-196836 |
| Vitamin D (calciferol) metabolism REACT:R-HSA-196791 |
| Vitamin digestion and absorption KEGG:hsa04977 |
| Vitamins REACT:R-HSA-211916 |
| Vitamins B6 activation to pyridoxal phosphate REACT:R-HSA-964975 |
| VLDL biosynthesis REACT:R-HSA-8866423 |
| VLDL interactions REACT:R-HSA-8855121 |
| VLDLR internalisation and degradation REACT:R-HSA-8866427 |
| Voltage gated Potassium channels REACT:R-HSA-1296072 |
| Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization REACT:R-HSA-180897 |
| Vpr-mediated nuclear import of PICs REACT:R-HSA-180910 |
| Vpu mediated degradation of CD4 REACT:R-HSA-180534 |
| vRNA Synthesis REACT:R-HSA-192814 |
| vRNP Assembly REACT:R-HSA-192905 |
| V-type ATPase, eukaryotes KEGG:hsa_M00160 |
| VxPx cargo-targeting to cilium REACT:R-HSA-5620916 |
| Wax biosynthesis REACT:R-HSA-8848584 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 REACT:R-HSA-5140745 |
| WNT5A-dependent internalization of FZD4 REACT:R-HSA-5099900 |
| WNT ligand biogenesis and trafficking REACT:R-HSA-3238698 |
| WNT ligand secretion is abrogated by the PORCN inhibitor LGK974 REACT:R-HSA-5340573 |
| WNT mediated activation of DVL REACT:R-HSA-201688 |
| Wnt signaling KEGG:hsa_M00677 |
| Wnt signaling pathway KEGG:hsa04310 |
| XAV939 inhibits tankyrase, stabilizing AXIN REACT:R-HSA-5545619 |
| XBP1(S) activates chaperone genes REACT:R-HSA-381038 |
| Xenobiotics REACT:R-HSA-211981 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression REACT:R-HSA-2032785 |
| ZBP1(DAI) mediated induction of type I IFNs REACT:R-HSA-1606322 |
| Zinc efflux and compartmentalization by the SLC30 family REACT:R-HSA-435368 |
| Zinc influx into cells by the SLC39 gene family REACT:R-HSA-442380 |
| Zinc transporters REACT:R-HSA-435354 |
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