Target_Summary_ID
stringclasses
200 values
Target_Sentence_Index
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4
7
External
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2 values
Target_Sentence_factual
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19
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Target_Sentence_non_factual
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19
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Original_Abstract
stringclasses
200 values
t0
t0_1
yes
The skin patch and the vaginal (birth canal) ring are two methods of birth control.
The skin patch and the vaginal (birth canal) ring are five methods of birth control.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_2
yes
Both methods contain the hormones estrogen and progestin.
Both methods contain the hormones testosterone and progestin.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_3
yes
The patch is a small, thin, adhesive square that is applied to the skin.
The patch is a large, thin, adhesive square that is applied to the skin.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_4
yes
The contraceptive vaginal ring is a flexible, lightweight device that is inserted into the vagina.
The contraceptive vaginal ring is a rigid, lightweight device that is inserted into the vagina.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_5
yes
Both methods release drugs like those in birth control pills.
Both methods release chemicals like those in birth control pills.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_6
yes
These methods could be used more consistently than pills because they do not require a daily dose.
These methods could not be used more consistently than pills because they do not require a daily dose.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_7
yes
This review looked at how well the methods worked to prevent pregnancy, if they caused bleeding problems, if women used them as prescribed, and how safe they were.
This review looked at how well the methods worked to prevent pregnancy, if they caused bleeding problems, if women avoided them as prescribed, and how safe they were.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_8
no
Through February 2013, we did computer searches for randomized controlled trials of the skin patch or vaginal ring compared to pills for birth control.
Through February 2013, we did computer searches for randomized controlled trials of the skin patch or vaginal ring compared to injections for birth control.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_9
yes
Pills included types with both estrogen and progestin.
Pills included types with both testosterone and progestin.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_10
no
We wrote to researchers to find other trials.
We wrote to researchers to ignore other trials.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_11
no
We found 18 trials.
We found 25 trials.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_12
no
Of six patch trials, five compared the marketed patch to birth control pills and one studied a patch being developed.
Of eight patch trials, five compared the marketed patch to birth control pills and one studied a patch being developed.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_13
no
Of 12 ring trials, 11 looked at the marketed ring and pills while one studied a ring being developed.
Of 15 ring trials, 11 looked at the marketed ring and pills while one studied a ring being developed.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_14
yes
The methods compared had similar pregnancy rates.
The methods compared had dissimilar pregnancy rates.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_15
no
Patch users reported using their method more consistently than the pill group did.
Patch users reported using their method less consistently than the pill group did.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_16
yes
Only half of the patch studies had data on pregnancy or whether the women used the method correctly.
Only two-thirds of the patch studies had data on pregnancy or whether the women used the method correctly.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_17
yes
However, most of the ring studies had those data.
However, most of the ring studies did not have those data.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_18
no
Patch users were more likely than pill users to drop out early from the trial.
Patch users were less likely than pill users to drop out early from the trial.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_19
no
Ring users were not more likely to drop out early.
Ring users were more likely to drop out early.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_20
no
Compared to pill users, users of the marketed patch had more breast discomfort, painful periods, nausea, and vomiting.
Compared to pill users, users of the marketed patch had less breast discomfort, painful periods, nausea, and vomiting.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_21
no
Ring users had more vaginal irritation and discharge than pill users but less nausea, acne, irritability, depression, and emotional changes.
Ring users had more vaginal irritation and discharge than pill users but more nausea, acne, irritability, depression, and emotional changes.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_22
yes
Ring users often had fewer bleeding problems than pill users.
Ring users often had more bleeding problems than pill users.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_23
yes
The quality of information was classed as low for the patch trials and moderate for the ring studies.
The quality of information was classed as high for the patch trials and moderate for the ring studies.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_24
yes
Lower quality was due to not reporting how groups were assigned or not having good outcome measures.
Higher quality was due to not reporting how groups were assigned or not having good outcome measures.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_25
no
Other issues were high losses and taking assigned women out of the analysis.
Other issues were low losses and taking assigned women out of the analysis.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t0
t0_26
yes
Studies of the patch and ring should provide more detail on whether women used the method correctly.
Studies of the patch and ring should provide less detail on whether women used the method correctly.
The delivery of combination contraceptive steroids from a transdermal contraceptive patch or a contraceptive vaginal ring offers potential advantages over the traditional oral route. The transdermal patch and vaginal ring could require a lower dose due to increased bioavailability and improved user compliance. Objectiv...
t1
t1_1
no
Excess body weight has become a health problem around the world.
Excess body weight has not become a health problem around the world.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_2
no
Being overweight or obese may affect how well some birth control methods work to prevent pregnancy.
Being overweight or obese may not affect how well some birth control methods work to prevent pregnancy.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_3
no
Hormonal birth control includes pills, the skin patch, the vaginal ring, implants, injectables, and hormonal intrauterine contraception (IUC).
Hormonal birth control includes pills, the skin patch, the vaginal ring, implants, injectables, and hormonal intrauterine contraception (CIV).
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_4
no
Until 4 August 2016, we did computer searches for studies of hormonal birth control among women who were overweight or obese.
Until 6 August 2016, we did computer searches for studies of hormonal birth control among women who were overweight or obese.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_5
yes
We looked for studies that compared overweight or obese women with women of normal weight or body mass index (BMI).
We looked for studies that compared overweight or obese women with women of abnormal weight or body mass index (BMI).
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_6
yes
The formula for BMI is weight (kg) / height (m) 2 .
The formula for BMI is weight (kg) / height (m) 3 .
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_7
no
We included all study designs.
We excluded all study designs.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_8
no
For the original review, we wrote to investigators to find other studies we might have missed.
For the original review, we wrote to investigators to lose other studies we might have missed.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_9
no
With 8 studies added in this update, we had 17 with a total of 63,813 women.
With 10 studies added in this update, we had 17 with a total of 63,813 women.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_10
no
We focus here on 12 studies with high, moderate, or low quality results.
We focus here on 15 studies with high, moderate, or low quality results.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_11
no
Most did not show more pregnancies for overweight or obese women.
Most did not show fewer pregnancies for overweight or obese women.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_12
no
Two of five studies using birth control pills found differences between BMI groups.
Three of five studies using birth control pills found differences between BMI groups.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_13
no
In one, overweight women had a higher pregnancy risk.
In one, overweight women had a lower pregnancy risk.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_14
no
The other found a lower pregnancy rate for obese women versus nonobese women.
The other found a higher pregnancy rate for obese women versus nonobese women.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_15
yes
The second study also tested a new skin patch.
The third study also tested a new skin patch.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_16
no
Obese women in the patch group had a higher pregnancy rate.
Obese women in the patch group had a lower pregnancy rate.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_17
no
Of five implant studies, two showed differences among weight groups.
Of seven implant studies, two showed differences among weight groups.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_18
yes
They studied the older six‐capsule implant.
They studied the older eight‐capsule implant.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_19
yes
One study showed a higher pregnancy rate in years 6 and 7 combined for women weighing 70 kg or more.
One study showed a higher pregnancy rate in years 6 and 7 combined for women weighing 80 kg or more.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_20
no
The other reported pregnancy differences in year 5 among the lower weight groups only.
The other reported pregnancy differences in year 8 among the lower weight groups only.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_21
no
Results for other methods of birth control did not show overweight or obesity related to pregnancy rate.
Results for other methods of birth control did not show underweight or obesity related to pregnancy rate.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_22
yes
Those methods included an injectable, hormonal IUC, and the two‐rod and single‐rod implants.
Those methods included an injectable, hormonal IUC, and the three‐rod and single‐rod implants.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_23
no
These studies generally did not show an association of BMI or weight with the effect of hormonal methods.
These studies generally did not show an association of BMI or weight with the effect of non-hormonal methods.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_24
no
We found few studies for most methods.
We found many studies for most methods.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_25
no
Studies using BMI rather than weight can show whether body fat is related to how well birth control prevents pregnancy.
Studies using BMI rather than weight cannot show whether body fat is related to how well birth control prevents pregnancy.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t1
t1_26
no
The methods studied here work very well when used according to directions.
The methods studied here do not work very well when used according to directions.
Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal contraceptives include oral contraceptives (OCs), injectables, implants, hormonal intrauterine contraception (IUC), the transde...
t2
t2_1
no
Cluster headaches are excruciating headaches of extreme intensity.
Cluster headaches are mild headaches of extreme intensity.
This is an updated version of the original Cochrane review published in Issue 4, 2010 ( Law 2010 ). Cluster headache is an uncommon, severely painful, and disabling condition, with rapid onset. Validated treatment options are limited; first‐line therapy includes inhaled oxygen. Other therapies such as intranasal lignoc...
t2
t2_2
yes
They can last for several hours, are usually on one side of the head only, and affect men more than women.
They can last for several hours, are usually on one side of the head only, and affect women more than men.
This is an updated version of the original Cochrane review published in Issue 4, 2010 ( Law 2010 ). Cluster headache is an uncommon, severely painful, and disabling condition, with rapid onset. Validated treatment options are limited; first‐line therapy includes inhaled oxygen. Other therapies such as intranasal lignoc...
t2
t2_3
yes
Multiple headaches can occur over several days.
Multiple headaches cannot occur over several days.
This is an updated version of the original Cochrane review published in Issue 4, 2010 ( Law 2010 ). Cluster headache is an uncommon, severely painful, and disabling condition, with rapid onset. Validated treatment options are limited; first‐line therapy includes inhaled oxygen. Other therapies such as intranasal lignoc...
t2
t2_4
yes
Fast pain relief is important because of the intense nature of the pain with cluster headache.
Slow pain relief is important because of the intense nature of the pain with cluster headache.
This is an updated version of the original Cochrane review published in Issue 4, 2010 ( Law 2010 ). Cluster headache is an uncommon, severely painful, and disabling condition, with rapid onset. Validated treatment options are limited; first‐line therapy includes inhaled oxygen. Other therapies such as intranasal lignoc...
t2
t2_5
no
Triptans are a type of drug used to treat migraine.
Triptans are a type of drug used to prevent migraine.
This is an updated version of the original Cochrane review published in Issue 4, 2010 ( Law 2010 ). Cluster headache is an uncommon, severely painful, and disabling condition, with rapid onset. Validated treatment options are limited; first‐line therapy includes inhaled oxygen. Other therapies such as intranasal lignoc...
t2
t2_6
no
Although migraine is different from cluster headache, there are reasons to believe that some forms of these drugs could be useful in cluster headache.
Although migraine is different from cluster headache, there are reasons to believe that some forms of these treatments could be useful in cluster headache.
This is an updated version of the original Cochrane review published in Issue 4, 2010 ( Law 2010 ). Cluster headache is an uncommon, severely painful, and disabling condition, with rapid onset. Validated treatment options are limited; first‐line therapy includes inhaled oxygen. Other therapies such as intranasal lignoc...
t2
t2_7
no
Triptans can be given by injection under the skin (subcutaneously) or by a spray into the nose (intranasally) to produce fast pain relief.
Triptans can be given by injection under the skin (subcutaneously) or by a spray into the mouth (orally) to produce fast pain relief.
This is an updated version of the original Cochrane review published in Issue 4, 2010 ( Law 2010 ). Cluster headache is an uncommon, severely painful, and disabling condition, with rapid onset. Validated treatment options are limited; first‐line therapy includes inhaled oxygen. Other therapies such as intranasal lignoc...
t2
t2_8
no
The review found six studies examining two different triptans.
The review found eight studies examining two different triptans.
This is an updated version of the original Cochrane review published in Issue 4, 2010 ( Law 2010 ). Cluster headache is an uncommon, severely painful, and disabling condition, with rapid onset. Validated treatment options are limited; first‐line therapy includes inhaled oxygen. Other therapies such as intranasal lignoc...
t2
t2_9
no
Within 15 minutes of using subcutaneous sumatriptan 6 mg, almost 8 in 10 participants had no worse than mild pain, and 5 in 10 were pain‐free.
Within 20 minutes of using subcutaneous sumatriptan 6 mg, almost 8 in 10 participants had no worse than mild pain, and 5 in 10 were pain‐free.
This is an updated version of the original Cochrane review published in Issue 4, 2010 ( Law 2010 ). Cluster headache is an uncommon, severely painful, and disabling condition, with rapid onset. Validated treatment options are limited; first‐line therapy includes inhaled oxygen. Other therapies such as intranasal lignoc...
t2
t2_10
no
Within 15 minutes of using intranasal zolmitriptan 5 mg, about 3 in 10 had no worse than mild pain, and 1 in 10 was pain‐free.
Within 20 minutes of using intranasal zolmitriptan 5 mg, about 3 in 10 had no worse than mild pain, and 1 in 10 was pain‐free.
This is an updated version of the original Cochrane review published in Issue 4, 2010 ( Law 2010 ). Cluster headache is an uncommon, severely painful, and disabling condition, with rapid onset. Validated treatment options are limited; first‐line therapy includes inhaled oxygen. Other therapies such as intranasal lignoc...
t2
t2_11
yes
Adverse events were more common with a triptan than with placebo but they were generally of mild to moderate severity.
Adverse events were more common with a triptan than with placebo but they were generally of severe to extreme severity.
This is an updated version of the original Cochrane review published in Issue 4, 2010 ( Law 2010 ). Cluster headache is an uncommon, severely painful, and disabling condition, with rapid onset. Validated treatment options are limited; first‐line therapy includes inhaled oxygen. Other therapies such as intranasal lignoc...
t3
t3_1
yes
Sugar‐sweetened beverages (SSBs) are cold and hot drinks with added sugar.
Sugar‐sweetened beverages (SSBs) are cold and hot drinks without added sugar.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_2
yes
Common SSBs are non‐diet soft drinks, regular soda, iced tea, sports drinks, energy drinks, fruit punches, sweetened waters, and sweetened tea and coffee.
Common SSBs are non‐diet soft drinks, regular soda, iced tea, sports drinks, energy drinks, fruit punches, sweetened waters, and unsweetened tea and coffee.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_3
no
Research shows that people who drink a lot of SSBs often gain weight.
Research shows that people who drink a lot of SSBs often lose weight.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_4
no
Drinking a lot of SSBs can also increase the risk of diabetes, heart disease, and dental decay.
Drinking a lot of SSBs can also decrease the risk of diabetes, heart disease, and dental decay.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_5
yes
Doctors therefore recommend that children, teenagers and adults drink fewer SSBs.
Doctors therefore recommend that children, teenagers and adults drink more SSBs.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_6
no
Governments, businesses, schools and workplaces have taken various measures to support healthier beverage choices.
Governments, businesses, schools and workplaces have taken various measures to oppose healthier beverage choices.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_7
no
We wanted to find out whether the measures taken so far have been successful in helping people to drink fewer SSBs to improve their health.
We wanted to find out whether the measures taken so far have been unsuccessful in helping people to drink fewer SSBs to improve their health.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_8
no
We focused on measures that change the environment in which people make beverage choices.
We focused on measures that change the environment in which people avoid beverage choices.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_9
yes
We did not look at studies on educational programmes or on SSB taxes, as these are examined in separate reviews.
We did not look at studies on educational programmes or on SSB taxes, as these are ignored in separate reviews.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_10
no
We searched for all available studies meeting clearly‐defined criteria to answer this question.
We searched for no available studies meeting clearly‐defined criteria to answer this question.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_11
no
We found 58 studies, which included more than one million adults, teenagers and children.
We found 72 studies, which included more than one million adults, teenagers and children.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_12
no
Most studies lasted about one year, and were done in schools, stores or restaurants.
Most studies lasted about two years, and were done in schools, stores or restaurants.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_13
no
Some studies used methods that are not very reliable.
Some studies used methods that are extremely reliable.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_14
yes
For example, in some studies participants were simply asked how much SSB they drank, which is not very reliable, as people sometimes forget how much SSB they drank.
For example, in some studies participants were simply asked how much SSB they drank, which is very reliable, as people sometimes forget how much SSB they drank.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_15
yes
Some of the findings of our review may therefore change when more and better studies become available.
Some of the findings of our review may therefore not change when more and better studies become available.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_16
no
We have found some evidence that some of the measures implemented to help people drink fewer SSBs have been successful, including the following: Labels which are easy to understand, such as traffic‐light labels, and labels which rate the healthfulness of beverages with stars or numbers.
We have found some evidence that some of the measures implemented to help people drink fewer SSBs have not been successful, including the following: Labels which are easy to understand, such as traffic‐light labels, and labels which rate the healthfulness of beverages with stars or numbers.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_17
no
Limits to the availability of SSB in schools (e.g. replacing SSBs with water in school cafeterias).
Limits to the availability of SSB in schools (e.g. replacing SSBs with juice in school cafeterias).
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_18
no
Price increases on SSBs in restaurants, stores and leisure centres.
Price decreases on SSBs in restaurants, stores and leisure centres.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_19
no
Children’s menus in chain restaurants which include healthier beverages as their standard beverage.
Children’s menus in chain restaurants which do not include healthier beverages as their standard beverage.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_20
no
Promotion of healthier beverages in supermarkets.
Promotion of unhealthier beverages in supermarkets.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_21
no
Government food benefits (e.g. food stamps) which cannot be used to buy SSBs.
Government food benefits (e.g. food stamps) which can be used to buy SSBs.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_22
no
Community campaigns focused on SSBs.
Community campaigns focused on vaccines.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_23
yes
Measures that improve the availability of low‐calorie beverages at home, e.g. through home deliveries of bottled water and diet beverages.
Measures that improve the availability of high‐calorie beverages at home, e.g. through home deliveries of bottled water and diet beverages.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_24
yes
We have also found some evidence that improved availability of drinking water and diet beverages at home can help people lose weight.
We have also found some evidence that improved availability of drinking water and diet beverages at home cannot help people lose weight.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_25
no
There are also other measures which may influence how much SSB people drink, but for these the available evidence is less certain.
There are also other measures which may influence how much SSB people drink, but for these the available evidence is more certain.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_26
no
Some, but not all studies found that such measures can have effects which were not intended and which may be negative.
Some, but not all studies found that such measures can have effects which were not intended and which may be positive.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_27
yes
Some studies reported that profits of stores and restaurants decreased when the measures were implemented, but other studies showed that profits increased or stayed the same.
Some studies reported that profits of stores and restaurants increased when the measures were implemented, but other studies showed that profits increased or stayed the same.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_28
yes
Children who get free drinking water in schools may drink less milk.
Children who get free drinking water in schools may drink more milk.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_29
no
Some studies reported that people were unhappy with the measures.
Some studies reported that people were happy with the measures.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_30
no
We also looked at studies on sugar‐sweetened milk.
We also looked at studies on sugar‐sweetened juice.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_31
no
We found that small prizes for children who chose plain milk in their school cafeteria, as well as emoticon labels, may help children drink less sugar‐sweetened milk.
We found that small prizes for children who chose plain milk in their school cafeteria, as well as emoticon labels, may help children drink more sugar‐sweetened milk.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_32
yes
However, this may also drive up the share of milk which is wasted because children choose but do not drink it.
However, this may also drive up the share of milk which is saved because children choose but do not drink it.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_33
no
Our review shows that measures which change the environment in which people make beverage choices can help people drink less SSB.
Our review shows that measures which change the environment in which people make beverage choices can help people drink more SSB.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_34
no
Based on our findings we suggest that such measures may be used more widely.
Based on our findings we suggest that such measures may not be used more widely.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t3
t3_35
no
Government officials, business people and health professionals implementing such measures should work together with researchers to find out more about their effects in the short and long term.
Government officials, business people and health professionals implementing such measures should refuse to work together with researchers to find out more about their effects in the short and long term.
Frequent consumption of excess amounts of sugar‐sweetened beverages (SSB) is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. Environmental interventions, i.e. interventions that alter the physical or social environment in which individuals make beverage choices, have been advocated...
t4
t4_1
yes
A baby may be in this situation because the placenta is no longer functioning well and this means the baby may be short of nutrition or oxygen.
A baby may be in this situation because the placenta is no longer functioning well and this means the baby may not be short of nutrition or oxygen.
Fetal compromise in the term pregnancy is suspected when the following clinical indicators are present: intrauterine growth restriction (IUGR), decreased fetal movement (DFM), or when investigations such as cardiotocography (CTG) and ultrasound reveal results inconsistent with standard measurements. Pathological result...
t4
t4_2
no
We asked in this Cochrane review if it is better to induce labour or do a caesarean section (both ways of ensuring the baby is born earlier) rather than letting the pregnancy continue until labour starts by itself.
We asked in this Cochrane review if it is better to induce labour or do a vaginal delivery (both ways of ensuring the baby is born earlier) rather than letting the pregnancy continue until labour starts by itself.
Fetal compromise in the term pregnancy is suspected when the following clinical indicators are present: intrauterine growth restriction (IUGR), decreased fetal movement (DFM), or when investigations such as cardiotocography (CTG) and ultrasound reveal results inconsistent with standard measurements. Pathological result...