acc1 stringclasses 995 values | acc2 stringclasses 978 values | Ce_1111_poisson float64 -0.21 0.99 ⌀ | Ce_1111_wcc float64 0 1 ⌀ | Ce_1111_apex float64 0 1 ⌀ | Ce_1111_pq_euc float64 -0.41 1 ⌀ | Ce_6mg_1203_poisson float64 -0.26 0.98 ⌀ | Ce_6mg_1203_wcc float64 0 1 ⌀ | Ce_6mg_1203_apex float64 0 1 ⌀ | Ce_6mg_1203_pq_euc float64 -0.41 1 ⌀ | Ce_BNF_wan_60_1209_poisson float64 -0.29 0.99 ⌀ | Ce_BNF_wan_60_1209_wcc float64 0 1 ⌀ | Ce_BNF_wan_60_1209_apex float64 0 1 ⌀ | Ce_BNF_wan_60_1209_pq_euc float64 -0.41 1 ⌀ | Ce_CRF_wan_60_1209_poisson float64 -0.21 0.99 ⌀ | Ce_CRF_wan_60_1209_wcc float64 0 1 ⌀ | Ce_CRF_wan_60_1209_apex float64 0 1 ⌀ | Ce_CRF_wan_60_1209_pq_euc float64 -0.41 1 ⌀ | Ce_beadsB_wan_60_1208_poisson float64 -0.47 0.88 ⌀ | Ce_beadsB_wan_60_1208_wcc float64 0 1 ⌀ | Ce_beadsB_wan_60_1208_apex float64 0 1 ⌀ | Ce_beadsB_wan_60_1208_pq_euc float64 -0.41 1 ⌀ | Ce_beadsC_wan_60_1209_poisson float64 -0.11 0.95 ⌀ | Ce_beadsC_wan_60_1209_wcc float64 0 1 ⌀ | Ce_beadsC_wan_60_1209_apex float64 0 1 ⌀ | Ce_beadsC_wan_60_1209_pq_euc float64 -0.41 1 ⌀ | Ce_beadsL_1206_poisson float64 -0.22 1 ⌀ | Ce_beadsL_1206_wcc float64 0 1 ⌀ | Ce_beadsL_1206_apex float64 0 1 ⌀ | Ce_beadsL_1206_pq_euc float64 -0.41 1 ⌀ | Ce_beadsN_wan_60_1208_poisson float64 -0.23 0.98 ⌀ | Ce_beadsN_wan_60_1208_wcc float64 0 0.97 ⌀ | Ce_beadsN_wan_60_1208_apex float64 0 1 ⌀ | Ce_beadsN_wan_60_1208_pq_euc float64 -0.41 1 ⌀ | Ce_beadsR_wan_60_1209_poisson float64 -0.1 0.89 ⌀ | Ce_beadsR_wan_60_1209_wcc float64 0 1 ⌀ | Ce_beadsR_wan_60_1209_apex float64 0 1 ⌀ | Ce_beadsR_wan_60_1209_pq_euc float64 -0.41 0.9 ⌀ | Ce_beadsflow_1206_poisson float64 -0.23 0.98 ⌀ | Ce_beadsflow_1206_wcc float64 0 1 ⌀ | Ce_beadsflow_1206_apex float64 0 1 ⌀ | Ce_beadsflow_1206_pq_euc float64 -0.41 1 ⌀ | Ce_ups_1206_poisson float64 -0.42 0.97 ⌀ | Ce_ups_1206_wcc float64 0 0.99 ⌀ | Ce_ups_1206_apex float64 0 1 ⌀ | Ce_ups_1206_pq_euc float64 -0.41 0.93 ⌀ | Dm_1107_DSL2_poisson float64 -0.25 0.99 ⌀ | Dm_1107_DSL2_wcc float64 0 1 ⌀ | Dm_1107_DSL2_apex float64 0 1 ⌀ | Dm_1107_DSL2_pq_euc float64 -0.41 1 ⌀ | Dm_1107_Dem_poisson float64 -0.3 0.97 ⌀ | Dm_1107_Dem_wcc float64 0 1 ⌀ | Dm_1107_Dem_apex float64 0 1 ⌀ | Dm_1107_Dem_pq_euc float64 -0.39 0.92 ⌀ | Dm_1201_Dem_poisson float64 -0.3 0.96 ⌀ | Dm_1201_Dem_wcc float64 0 1 ⌀ | Dm_1201_Dem_apex float64 0 1 ⌀ | Dm_1201_Dem_pq_euc float64 -0.41 0.94 ⌀ | Dm_SL2_wan_110_1208_poisson float64 -0.15 0.97 ⌀ | Dm_SL2_wan_110_1208_wcc float64 0 1 ⌀ | Dm_SL2_wan_110_1208_apex float64 0 1 ⌀ | Dm_SL2_wan_110_1208_pq_euc float64 -0.41 1 ⌀ | Hs_CB660_1105_poisson float64 -0.15 0.94 ⌀ | Hs_CB660_1105_wcc float64 0 1 ⌀ | Hs_CB660_1105_apex float64 0 1 ⌀ | Hs_CB660_1105_pq_euc float64 -0.41 1 ⌀ | Hs_G166_1104_poisson float64 -0.19 0.98 ⌀ | Hs_G166_1104_wcc float64 0 1 ⌀ | Hs_G166_1104_apex float64 0 1 ⌀ | Hs_G166_1104_pq_euc float64 -0.41 1 ⌀ | Hs_G166_1105_poisson float64 -0.26 1 ⌀ | Hs_G166_1105_wcc float64 0 1 ⌀ | Hs_G166_1105_apex float64 0 1 ⌀ | Hs_G166_1105_pq_euc float64 -0.41 1 ⌀ | Hs_hekN_1108_poisson float64 -0.15 0.98 ⌀ | Hs_hekN_1108_wcc float64 0 1 ⌀ | Hs_hekN_1108_apex float64 0 1 ⌀ | Hs_hekN_1108_pq_euc float64 -0.41 1 ⌀ | Hs_hekN_1201_poisson float64 -0.16 1 ⌀ | Hs_hekN_1201_wcc float64 0 1 ⌀ | Hs_hekN_1201_apex float64 0 1 ⌀ | Hs_hekN_1201_pq_euc float64 -0.41 1 ⌀ | Hs_hekN_ph_hcw120_1_poisson float64 -0.12 0.99 ⌀ | Hs_hekN_ph_hcw120_1_wcc float64 0 1 ⌀ | Hs_hekN_ph_hcw120_1_apex float64 0 1 ⌀ | Hs_hekN_ph_hcw120_1_pq_euc float64 -0.41 0 ⌀ | Hs_hekN_ph_hcw120_2_poisson float64 -0.12 0.93 ⌀ | Hs_hekN_ph_hcw120_2_wcc float64 0 1 ⌀ | Hs_hekN_ph_hcw120_2_apex float64 0 1 ⌀ | Hs_hekN_ph_hcw120_2_pq_euc float64 -0.41 1 ⌀ | Hs_hek_kinase95_poisson float64 -0.23 0.95 ⌀ | Hs_hek_kinase95_wcc float64 0 1 ⌀ | Hs_hek_kinase95_apex float64 0 1 ⌀ | Hs_hek_kinase95_pq_euc float64 -0.41 0.95 ⌀ | Hs_hek_wan_membraneopioid72_poisson float64 -0.57 0.97 ⌀ | Hs_hek_wan_membraneopioid72_wcc float64 0 1 ⌀ | Hs_hek_wan_membraneopioid72_apex float64 0 1 ⌀ | Hs_hek_wan_membraneopioid72_pq_euc float64 -0.41 0.98 ⌀ | Hs_helaC_mar_SGF_poisson float64 -0.48 0.96 ⌀ | Hs_helaC_mar_SGF_wcc float64 0 1 ⌀ | Hs_helaC_mar_SGF_apex float64 0 1 ⌀ | Hs_helaC_mar_SGF_pq_euc float64 -0.41 1 ⌀ | Hs_helaC_mar_ief3_10_poisson float64 -0.43 1 ⌀ | Hs_helaC_mar_ief3_10_wcc float64 0 1 ⌀ | Hs_helaC_mar_ief3_10_apex float64 0 1 ⌀ | Hs_helaC_mar_ief3_10_pq_euc float64 -0.41 1 ⌀ | Hs_helaC_mar_ief5_8_poisson float64 -0.4 0.97 ⌀ | Hs_helaC_mar_ief5_8_wcc float64 0 1 ⌀ | Hs_helaC_mar_ief5_8_apex float64 0 1 ⌀ | Hs_helaC_mar_ief5_8_pq_euc float64 -0.41 1 ⌀ | Hs_helaC_ph_tcs269_1_poisson float64 -0.09 0.87 ⌀ | Hs_helaC_ph_tcs269_1_wcc float64 0 1 ⌀ | Hs_helaC_ph_tcs269_1_apex float64 0 1 ⌀ | Hs_helaC_ph_tcs269_1_pq_euc float64 -0.26 0.23 ⌀ | Hs_helaC_ph_tcs269_2_poisson float64 -0.11 0.93 ⌀ | Hs_helaC_ph_tcs269_2_wcc float64 0 1 ⌀ | Hs_helaC_ph_tcs269_2_apex float64 0 1 ⌀ | Hs_helaC_ph_tcs269_2_pq_euc float64 0 0 ⌀ | Hs_helaC_ph_wax43_poisson float64 -0.53 0.94 ⌀ | Hs_helaC_ph_wax43_wcc float64 0 1 ⌀ | Hs_helaC_ph_wax43_apex float64 0 1 ⌀ | Hs_helaC_ph_wax43_pq_euc float64 -0.41 0 ⌀ | Hs_helaN_1003_poisson float64 -0.16 0.99 ⌀ | Hs_helaN_1003_wcc float64 0 1 ⌀ | Hs_helaN_1003_apex float64 0 1 ⌀ | Hs_helaN_1003_pq_euc float64 -0.41 1 ⌀ | Hs_helaN_1010_poisson float64 -0.17 0.98 ⌀ | Hs_helaN_1010_wcc float64 0 1 ⌀ | Hs_helaN_1010_apex float64 0 1 ⌀ | Hs_helaN_1010_pq_euc float64 -0.41 1 ⌀ | Hs_helaN_mar_SGF_poisson float64 -0.59 1 ⌀ | Hs_helaN_mar_SGF_wcc float64 0 1 ⌀ | Hs_helaN_mar_SGF_apex float64 0 1 ⌀ | Hs_helaN_mar_SGF_pq_euc float64 -0.41 1 ⌀ | Hs_helaN_mar_ief3_10_poisson float64 -0.48 1 ⌀ | Hs_helaN_mar_ief3_10_wcc float64 0 1 ⌀ | Hs_helaN_mar_ief3_10_apex float64 0 1 ⌀ | Hs_helaN_mar_ief3_10_pq_euc float64 -0.28 0.94 ⌀ | Hs_helaN_mar_ief5_8_poisson float64 -0.23 1 ⌀ | Hs_helaN_mar_ief5_8_wcc float64 0 1 ⌀ | Hs_helaN_mar_ief5_8_apex float64 0 1 ⌀ | Hs_helaN_mar_ief5_8_pq_euc float64 -0.41 1 ⌀ | Hs_helaN_ph_hcw120_1_poisson float64 -0.19 0.97 ⌀ | Hs_helaN_ph_hcw120_1_wcc float64 0 1 ⌀ | Hs_helaN_ph_hcw120_1_apex float64 0 1 ⌀ | Hs_helaN_ph_hcw120_1_pq_euc float64 0 0 ⌀ | Hs_helaN_ph_hcw120_2_poisson float64 -0.28 0.97 ⌀ | Hs_helaN_ph_hcw120_2_wcc float64 0 1 ⌀ | Hs_helaN_ph_hcw120_2_apex float64 0 1 ⌀ | Hs_helaN_ph_hcw120_2_pq_euc float64 -0.41 1 ⌀ | Hs_helaN_ph_saf48_poisson float64 -0.12 0.92 ⌀ | Hs_helaN_ph_saf48_wcc float64 0 1 ⌀ | Hs_helaN_ph_saf48_apex float64 0 1 ⌀ | Hs_helaN_ph_saf48_pq_euc float64 0 0 ⌀ | Hs_helaN_ph_tcs375_P1_poisson float64 -0.02 0.39 ⌀ | Hs_helaN_ph_tcs375_P1_wcc float64 0 0.88 ⌀ | Hs_helaN_ph_tcs375_P1_apex float64 0 1 ⌀ | Hs_helaN_ph_tcs375_P1_pq_euc float64 0 0 ⌀ | Hs_helaN_ph_tcs375_P2_poisson float64 -0.32 0.91 ⌀ | Hs_helaN_ph_tcs375_P2_wcc float64 0 0.98 ⌀ | Hs_helaN_ph_tcs375_P2_apex float64 0 1 ⌀ | Hs_helaN_ph_tcs375_P2_pq_euc float64 0 0 ⌀ | Hs_helaN_ph_tcs375_P3_poisson float64 -0.09 0.82 ⌀ | Hs_helaN_ph_tcs375_P3_wcc float64 0 1 ⌀ | Hs_helaN_ph_tcs375_P3_apex float64 0 1 ⌀ | Hs_helaN_ph_tcs375_P3_pq_euc float64 0 0 ⌀ | Hs_wan_aguhplc108_1204_poisson float64 -0.25 0.9 ⌀ | Hs_wan_aguhplc108_1204_wcc float64 0 0.97 ⌀ | Hs_wan_aguhplc108_1204_apex float64 0 1 ⌀ | Hs_wan_aguhplc108_1204_pq_euc float64 -0.41 0.88 ⌀ | Hs_wan_shuhplc94_1206_poisson float64 -0.29 0.98 ⌀ | Hs_wan_shuhplc94_1206_wcc float64 0 1 ⌀ | Hs_wan_shuhplc94_1206_apex float64 0 1 ⌀ | Hs_wan_shuhplc94_1206_pq_euc float64 -0.41 0.94 ⌀ | Mm_1106_poisson float64 -0.16 1 ⌀ | Mm_1106_wcc float64 0 1 ⌀ | Mm_1106_apex float64 0 1 ⌀ | Mm_1106_pq_euc float64 -0.41 1 ⌀ | Mm_1201_poisson float64 -0.15 1 ⌀ | Mm_1201_wcc float64 0 1 ⌀ | Mm_1201_apex float64 0 1 ⌀ | Mm_1201_pq_euc float64 -0.41 1 ⌀ | Sp_1103_Egg_poisson float64 -0.21 0.99 ⌀ | Sp_1103_Egg_wcc float64 0 1 ⌀ | Sp_1103_Egg_apex float64 0 1 ⌀ | Sp_1103_Egg_pq_euc float64 -0.41 1 ⌀ | Sp_1108_2ce_poisson float64 -0.11 0.96 ⌀ | Sp_1108_2ce_wcc float64 0 1 ⌀ | Sp_1108_2ce_apex float64 0 1 ⌀ | Sp_1108_2ce_pq_euc float64 -0.41 1 ⌀ | Sp_1108_BL_poisson float64 -0.09 0.98 ⌀ | Sp_1108_BL_wcc float64 0 1 ⌀ | Sp_1108_BL_apex float64 0 1 ⌀ | Sp_1108_BL_pq_euc float64 -0.41 1 ⌀ | Sp_1109_PF5_poisson float64 -0.13 0.94 ⌀ | Sp_1109_PF5_wcc float64 0 1 ⌀ | Sp_1109_PF5_apex float64 0 1 ⌀ | Sp_1109_PF5_pq_euc float64 -0.41 1 ⌀ | Sp_1109_UNF_poisson float64 -0.09 0.99 ⌀ | Sp_1109_UNF_wcc float64 0 1 ⌀ | Sp_1109_UNF_apex float64 0 1 ⌀ | Sp_1109_UNF_pq_euc float64 -0.41 1 ⌀ | Sp_60_121010_poisson float64 -0.21 0.97 ⌀ | Sp_60_121010_wcc float64 0 1 ⌀ | Sp_60_121010_apex float64 0 1 ⌀ | Sp_60_121010_pq_euc float64 -0.41 1 ⌀ | Sp_beadsALF_60_121014_poisson float64 -0.13 0.9 ⌀ | Sp_beadsALF_60_121014_wcc float64 0 1 ⌀ | Sp_beadsALF_60_121014_apex float64 0 1 ⌀ | Sp_beadsALF_60_121014_pq_euc float64 -0.41 0.95 ⌀ | Sp_beadsBNF_73_1201119_poisson float64 -0.2 0.96 ⌀ | Sp_beadsBNF_73_1201119_wcc float64 0 0.99 ⌀ | Sp_beadsBNF_73_1201119_apex float64 0 1 ⌀ | Sp_beadsBNF_73_1201119_pq_euc float64 -0.41 1 ⌀ | Sp_beadsL_60_121125_poisson float64 -0.16 0.99 ⌀ | Sp_beadsL_60_121125_wcc float64 0 1 ⌀ | Sp_beadsL_60_121125_apex float64 0 1 ⌀ | Sp_beadsL_60_121125_pq_euc float64 -0.41 1 ⌀ | Sp_iex_60_121019_poisson float64 -0.26 0.97 ⌀ | Sp_iex_60_121019_wcc float64 0 1 ⌀ | Sp_iex_60_121019_apex float64 0 1 ⌀ | Sp_iex_60_121019_pq_euc float64 -0.41 1 ⌀ | ext_Dm_guru float64 0 550 ⌀ | ext_Hs_malo float64 0 10 ⌀ | entropy_orig9k float64 0.76 1 ⌀ | zscore_orig9k float64 -0.96 53.3 ⌀ | nwdscore_orig9k float64 0.06 191 ⌀ | plate_zscore_orig9k float64 -1.11 12.6 ⌀ | uPeps_orig9k float64 2 192 ⌀ | ratio_orig9k float64 0 1 ⌀ | total_psms_orig9k float64 8 581k ⌀ | ratioTotalPSMs_orig9k float64 0 0.99 ⌀ | UtoTratio_orig9k float64 0.1 1 ⌀ | neg_ln_pval float64 0.04 96.8 ⌀ | pair_count float64 1 22 ⌀ | prey.bait.correlation float64 -0.03 0.9 ⌀ | valid.values float64 1 3 ⌀ | log10.prey.bait.ratio float64 -4.16 0.99 ⌀ | log10.prey.bait.expression.ratio float64 -3.46 2.95 ⌀ | hein_neg_ln_pval float64 0.75 61.1 ⌀ | hein_pair_count float64 1 18 ⌀ | ave_apsm float64 1 482 ⌀ | nwdscore_bioplex2 float64 0.01 226 ⌀ | zscore_bioplex2 float64 -1.62 80 ⌀ | plate_zscore_bioplex2 float64 -2.12 13.1 ⌀ | entropy_bioplex2 float64 0.76 1 ⌀ | uPeps_bioplex2 float64 2 192 ⌀ | ratio_bioplex2 float64 0 1 ⌀ | total_psms_bioplex2 float64 5 1.5M ⌀ | ratioTotalPSMs_bioplex2 float64 0 1 ⌀ | UtoTratio_bioplex2 float64 0.07 1 ⌀ | neg_ln_pval_bioplex2_Z4 float64 0.31 304 ⌀ | pair_count_bioplex2_Z4 float64 1 70 ⌀ | neg_ln_pval_bioplex2_Z2 float64 0 650 ⌀ | pair_count_bioplex2_Z2 float64 1 239 ⌀ | AvgSpec float64 | AvgP float64 | MaxP float64 | Fold_Change float64 | BFDR float64 | AvgSpec_nonciliated_bioid float64 1 36 ⌀ | AvgP_nonciliated_bioid float64 0 1 ⌀ | MaxP_nonciliated_bioid float64 0 1 ⌀ | Fold_Change_nonciliated_bioid float64 0.27 130 ⌀ | BFDR_nonciliated_bioid float64 0 0.78 ⌀ | neg_ln_pval_cilium_hygeo float64 -0 34.7 ⌀ | pair_count_cilium_hygeo float64 1 98 ⌀ | neg_ln_pval_cilium_hygeo_avgspec2 float64 -0 49.7 ⌀ | pair_count_cilium_hygeo_avgspec2 float64 1 97 ⌀ | neg_ln_pval_cilium_hygeo_avgspec4 float64 0 38.8 ⌀ | pair_count_cilium_hygeo_avgspec4 float64 1 96 ⌀ | SAij float64 -2.85 13.1 ⌀ | Sij float64 -0.39 6.62 ⌀ | Sji float64 -0.92 6.77 ⌀ | Mij float64 -2.85 6.69 ⌀ | neg_ln_pval_boldt_apms_hygeo float64 0 91.4 ⌀ | pair_count_boldt_apms_hygeo float64 1 157 ⌀ | neg_ln_pval_boldt_apms_hygeo_gt4 float64 0 91.4 ⌀ | pair_count_boldt_apms_hygeo_gt4 float64 1 157 ⌀ | neg_ln_pval_treiber_hygeo_gt4 float64 -0 726 ⌀ | pair_count_treiber_hygeo_gt4 float64 1 936 ⌀ | AvgSpec_youn float64 0.5 713 ⌀ | AvgP_youn float64 0 1 ⌀ | MaxP_youn float64 0 1 ⌀ | FoldChange float64 0.03 2.17k ⌀ | BFDR_youn float64 0 0.81 ⌀ | neg_ln_pval_youn_hygeo float64 -0 44.3 ⌀ | pair_count_youn_hygeo float64 1 139 ⌀ | neg_ln_pval_youn_hygeo_gt2 float64 -0 57.2 ⌀ | pair_count_youn_hygeo_gt2 float64 1 139 ⌀ | neg_ln_pval_youn_hygeo_gt4 float64 0 50.4 ⌀ | pair_count_youn_hygeo_gt4 float64 1 139 ⌀ | neg_ln_pval_treiber_hygeo_gt2 float64 -0 867 ⌀ | pair_count_treiber_hygeo_gt2 float64 1 1.21k ⌀ | ave_apsm_bp3_293T float64 1 628 ⌀ | nwdscore_bp3_293T float64 0.01 1.23k ⌀ | zscore_bp3_293T float64 -1.72 104 ⌀ | plate_zscore_bp3_293T float64 -2.48 13.1 ⌀ | entropy_bp3_293T float64 0.76 1 ⌀ | uPeps_bp3_293T float64 2 192 ⌀ | ratio_bp3_293T float64 0 1 ⌀ | total_psms_bp3_293T float64 6 2.74M ⌀ | ratioTotalPSMs_bp3_293T float64 0 0.72 ⌀ | UtoTratio_bp3_293T float64 0.06 1 ⌀ | ave_apsm_bp3_HCT116 float64 1 580 ⌀ | nwdscore_bp3_HCT116 float64 0.02 624 ⌀ | zscore_bp3_HCT116 float64 -1.78 100 ⌀ | plate_zscore_bp3_HCT116 float64 -2.26 15.9 ⌀ | entropy_bp3_HCT116 float64 0.77 1 ⌀ | uPeps_bp3_HCT116 float64 2 245 ⌀ | ratio_bp3_HCT116 float64 0 1 ⌀ | total_psms_bp3_HCT116 float64 2 1.33M ⌀ | ratioTotalPSMs_bp3_HCT116 float64 0 1 ⌀ | UtoTratio_bp3_HCT116 float64 0.04 1 ⌀ | neg_ln_pval_bp3_293T_Z2 float64 0 1.19k ⌀ | pair_count_bp3_293T_Z2 float64 1 445 ⌀ | neg_ln_pval_bp3_293T_Z4 float64 0.11 480 ⌀ | pair_count_bp3_293T_Z4 float64 1 118 ⌀ | 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Q15393 | Q9BRD0 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 8.723107 | 2 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 20.896639 | 9 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 6.729951 | 4 | null | null | null | null | null | null | null | null | null | null | null | 6.164948 | 6 | 11 | 0.06 | 0.41 | 0.313969 | 0.994539 | 15 | 0.867677 | 158,149 | 0.00014 | 0.681818 | null | null | null | null | null | null | null | null | null | null | 166.1406 | 68 | 55.111595 | 20 | 16.497483 | 6 | null | null | 179.983504 | 74 | 52.715251 | 20 | 1 |
Q15393 | Q7RTV0 | -0.017548 | 0 | 0 | -0.195313 | 0.553223 | 0.877441 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -0.012062 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -0.008118 | 0 | 0 | 0 | 0.933594 | 0.98291 | 1 | 0.365234 | -0.04715 | 0 | 0 | 0.052032 | -0.059174 | 0 | 0 | -0.012436 | 0.398193 | 0.529785 | 0 | 0.474121 | -0.012207 | 0 | 0 | 0 | 0.294922 | 0.426514 | 0 | 0.463135 | 0.496338 | 0.508789 | 0 | 0.492188 | 0.705078 | 0.762695 | 0 | 0.691895 | 0.608398 | 0.755859 | 1 | 0.691406 | 0.824219 | 0.865723 | 0 | 0 | 0.756348 | 0.814941 | 1 | 0 | -0.038757 | 0 | 0 | 0 | -0.051483 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.862793 | 0.880371 | 1 | 0.556152 | 0.757813 | 0.713379 | 0 | 0.520996 | 0 | 0 | 0 | 0 | 0.188232 | 0.235718 | 0 | 0 | 0 | 0 | 0 | 0 | 0.808105 | 0.817383 | 1 | 0 | 0.863281 | 0.870605 | 0 | 0 | 0.164673 | 0.565918 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.623535 | 0.864746 | 1 | 0 | -0.083374 | 0 | 0 | 0 | -0.078979 | 0 | 0 | -0.078064 | 0.198608 | 0.142334 | 0 | 0.051483 | 0.246948 | 0.320313 | 0 | 0.447266 | -0.036835 | 0 | 0 | 0.282715 | -0.004185 | 0.037781 | 0 | -0.15564 | 0 | 0 | 0 | 0 | 0.009621 | 0.036316 | 0 | -0.234619 | 0 | 0 | 0 | 0 | 0.08252 | 0.188721 | 0 | 0.343262 | 0 | 0 | 0 | 0 | -0.018356 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.299561 | 0.429688 | 0 | 0 | 0 | 0 | null | null | null | null | null | null | null | null | null | 13.691766 | 3 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 45.059173 | 10 | 22.216799 | 11 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 1.742311 | 1 | 1.768979 | 1 | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.107201 | 2 | 240 | 0.26 | 26.05 | 6.41763 | 0.990889 | 72 | 0.867677 | 158,149 | 0.00304 | 0.15 | 75 | 0.3 | 6.07 | 5.54617 | 0.99544 | 57 | 0.952007 | 83,149 | 0.0018 | 0.38 | 170.393491 | 70 | 96.837994 | 28 | 47.614922 | 12 | 55.139449 | 10 | 171.426369 | 73 | 103.469671 | 30 | 1 |
Q8TAD8 | Q15393 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 21 | 0.08 | 1.98 | 3.15362 | 0.996317 | 27 | 0.82195 | 73,046 | 0.00057 | 0.642857 | null | null | 2.533852 | 1 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 21 | 0.08 | 1.53 | 3.15362 | 0.996317 | 27 | 0.867677 | 158,149 | 0.00027 | 0.642857 | 9 | 0.1 | 0.16 | 0.408011 | 0.979869 | 13 | 0.952007 | 83,149 | 0.00022 | 0.722222 | 154.480689 | 49 | 59.010116 | 16 | null | null | null | null | 153.340033 | 49 | 58.48627 | 16 | 1 |
Q15393 | Q9NPA8 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 9.218036 | 16 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 2.012526 | 14 | null | null | 1.316091 | 2 | 2.871982 | 1 | 1.017669 | 16 | 1.710907 | 1 | 1 |
Q15393 | Q14CW9 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 23 | 0.09 | 2.24 | 2.69266 | 0.988212 | 31 | 0.82195 | 73,046 | 0.00063 | 0.673913 | null | null | 3.605328 | 1 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 23 | 0.08 | 1.75 | 2.69266 | 0.988212 | 31 | 0.867677 | 158,149 | 0.00029 | 0.673913 | 27 | 0.18 | 1.77 | 2.67355 | 0.996181 | 31 | 0.952007 | 83,149 | 0.00065 | 0.574074 | 7.776943 | 3 | 3.449043 | 1 | 7.354625 | 2 | 9.450684 | 2 | 10.640464 | 4 | 7.361483 | 2 | 1 |
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in Data Studio
hu.MAP3.0: Atlas of human protein complexes by integration of > 25,000 proteomic experiments.
Proteins interact with each other and organize themselves into macromolecular machines (ie. complexes) to carry out essential functions of the cell. We have a good understanding of a few complexes such as the proteasome and the ribosome but currently we have an incomplete view of all protein complexes as well as their functions. The hu.MAP attempts to address this lack of understanding by integrating several large scale protein interaction datasets to obtain the most comprehensive view of protein complexes. In hu.MAP 3.0 we integrated large scale affinity purification mass spectrometry (AP/MS) datasets from Bioplex, Bioplex2.0, Bioplex3.0, Boldt et al. and Hein et al., large scale biochemical fractionation data (Wan et al.), proximity labeling data (Gupta et al., Youn et al.), and RNA hairpin pulldown data (Treiber et al.) to produce a complex map with over 15k complexes.
Funding
NIH R00, NSF/BBSRC
Citation
Samantha N. Fischer, Erin R Claussen, Savvas Kourtis, Sara Sdelci, Sandra Orchard, Henning Hermjakob, Georg Kustatscher, Kevin Drew hu.MAP3.0: Atlas of human protein complexes by integration of > 25,000 proteomic experiments BioRxiv https://doi.org/10.1101/2024.10.11.617930
References
Kevin Drew, John B. Wallingford, Edward M. Marcotte hu.MAP 2.0: integration of over 15,000 proteomic experiments builds a global compendium of human multiprotein assemblies Mol Syst Biol (2021)17:e10016. https://doi.org/10.15252/msb.202010016
Kevin Drew, Chanjae Lee, Ryan L Huizar, Fan Tu, Blake Borgeson, Claire D McWhite, Yun Ma, John B Wallingford, Edward M Marcotte Integration of over 9,000 mass spectrometry experiments builds a global map of human protein complexes. Molecular Systems Biology (2017) 13, 932. DOI 10.15252/msb.20167490
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Associated code
Code examples using the hu.MAP 3.0 model and downstream analysis can be found on our GitHub
Usage
Accessing the model
hu.MAP 3.0 was built using the auto-ML tool AutoGluon and the TabularPredictor module is used to train, test, and make predictions with the model.
This can be downloaded using the following:
$ pip install autogluon==0.4.0
Then it can be imported as:
>>> from autogluon.tabular import TabularPredictor
Note that to perform operations with our model the 0.4.0 version must be used
Our trained model can be downloaded through Huggingface using huggingface_hub
>>> from huggingface_hub import snapshot_download
>>> model_dir = snapshot_download(repo_id="sfisch/hu.MAP3.0_AutoGluon")
>>> predictor = TabularPredictor.load(f"{model_dir}/huMAP3_20230503_complexportal_subset10kNEG_notScaled_accuracy")
Using the training and test data
Both the train and test feature matrices can be loaded using the Huggingface datasets library.
This can be done from the command-line using:
$ pip install datasets
When loading into Python use the following:
>>> from datasets import load_dataset
>>> dataset = load_dataset('sfisch/hu.MAP3.0')
Training and test feature matrices can then be accessed as separate objects:
>>> train = dataset["train"].to_pandas()
>>> test = dataset["test"].to_pandas()
Jupyter notebooks containing more in-depth examples of model training, testing, and generating predictions can be found on our GitHub
Accessing full feature matrix and all test/train interaction/complex files
All other files, such as the full feature matrix, can be accessed via Huggingface_hub.
>>> from huggingface_hub import hf_hub_download
>>> full_file = hf_hub_download(repo_id="sfisch/hu.MAP3.0", filename='full/humap3_full_feature_matrix_20220625.csv.gz', repo_type='dataset')
This just provides the file for download. Depending on your workflow, if you wish to use as a pandas dataframe for example:
>>> import pandas as pd
>>> full_featmat = pd.read_csv(full_file, compression="gzip")
The other complex/interaction files can be downloaded in the same manner. The files within the 'reference_interactions' directory contain the complexes split from Complex Portal into test and training sets. Within that directory you will also find the pairwise protein interactions that were used as positive and negative interactions for both the test and training sets.
Dataset card authors
Samantha Fischer (sfisch6@uic.edu)
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