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e529be7c-f360-4dba-b313-7f3fc240697a | Which of the following statements are True/False? 1. Hirsutism, which is defined as androgen-dependent excessive male pattern hair growth, affects approximately 25% of women. 2. Virilization refers to a condition in which androgen levels are sufficiently high to cause additional signs and symptoms. 3. Frequently, patie... | 1, 2, 3 True & 4, 5 false | 1, 3, 5 True & 2, 4 false | 2, 4, 5 True & 1, 3 false | 1, 2, 3, 4 True & 5 false | 2c | multi | Here statement 1 & 3 are wrong. It is actually a direct pick from harrison, an impoant topic for entrance examinations hirsutism is seen in 10% of woman. Acromegaly rarely causes hirsutism. Ref: Harrisons Principles of Medicine, 18th Edition, Pages 380-382 | Medicine | null | 132 | {
"Correct Answer": "2, 4, 5 True & 1, 3 false",
"Correct Option": "C",
"Options": {
"A": "1, 2, 3 True & 4, 5 false",
"B": "1, 3, 5 True & 2, 4 false",
"C": "2, 4, 5 True & 1, 3 false",
"D": "1, 2, 3, 4 True & 5 false"
},
"Question": "Which of the following statements are True/False? 1. Hirsu... | Which of the following statements are True/False? 1. Hirsutism, which is defined as androgen-dependent excessive male pattern hair growth, affects approximately 25% of women. 2. Virilization refers to a condition in which androgen levels are sufficiently high to cause additional signs and symptoms. 3. Frequently, patie... | Scores above 8 suggest excess androgen-mediated hair growth. | {
"A": "1, 2, 3 True & 4, 5 false",
"B": "1, 3, 5 True & 2, 4 false",
"C": "2, 4, 5 True & 1, 3 false",
"D": "1, 2, 3, 4 True & 5 false"
} | C. 2, 4, 5 True & 1, 3 false |
31868f6c-233a-40ee-880e-9c668509a8b1 | An ill 16 days old baby girl is brought to the emergency. On examination pallor and dyspnoea present with a respiratory rate of 85 per minute. Her HR is 200 bpm, hea sounds are distant and a gallop is heard. X-ray showed cardiomegaly. An echocardiogram shows dilated ventricles and dilation of the left atrium. An ECG sh... | CHF | Glycogen storage disease | Pericarditis | Aberrant left coronary aery arising from pulmonary aery | 0a | multi | In CHF pallor, dyspnoea, tachypnoea, tachycardia and cardiomegaly are common regardless of the cause.The most common causes of CHF in children include myocarditis caused by adenovirus and coxsackievirus B.The echocardiogram shows ventricular and left atrial dilatation as well as poor ventricular function. With glycogen... | Pediatrics | Impoant Viral Diseases in Children | 110 | {
"Correct Answer": "CHF",
"Correct Option": "A",
"Options": {
"A": "CHF",
"B": "Glycogen storage disease",
"C": "Pericarditis",
"D": "Aberrant left coronary aery arising from pulmonary aery"
},
"Question": "An ill 16 days old baby girl is brought to the emergency. On examination pallor and dy... | An ill 16 days old baby girl is brought to the emergency. On examination pallor and dyspnoea present with a respiratory rate of 85 per minute. Her HR is 200 bpm, hea sounds are distant and a gallop is heard. X-ray showed cardiomegaly. An echocardiogram shows dilated ventricles and dilation of the left atrium. An ECG sh... | Which of the following is the most likely diagnosis? | {
"A": "CHF",
"B": "Glycogen storage disease",
"C": "Pericarditis",
"D": "Aberrant left coronary aery arising from pulmonary aery"
} | A. CHF |
090f4f67-eab2-4ffc-a9d0-d03da739bf9f | A 19 year old female presents with pain in the neck for 5 days. She is not able to wear tie for her job because of neck pain. H/O fatigue and lethargy for 10 days. She had flu like symptoms 20 days ago which resolved spontaneously. BP 110/80 mmHg, Pulse 48/min. Extremities are cold and dry. Neck is very tender. ECG nor... | Atropine injection | Levothyroxine administration | Aspirin | Increase iodine intake in food | 2c | multi | Answer: c) Aspirin (SCHWARTZ 19TH ED, P-1525; SABISTON 19TH ED, P-895)Granulomatous or Subacute or De Quervain's thyroiditisMost commonly occurs in 30- 40 year-old womenStrong association with the HLA-B35Fever with Sudden or gradual onset of neck painH/o preceding URI; Viral etiologyGland - enlarged, tender, firmClassi... | Surgery | Thyroid Gland | 112 | {
"Correct Answer": "Aspirin",
"Correct Option": "C",
"Options": {
"A": "Atropine injection",
"B": "Levothyroxine administration",
"C": "Aspirin",
"D": "Increase iodine intake in food"
},
"Question": "A 19 year old female presents with pain in the neck for 5 days. She is not able to wear tie f... | A 19 year old female presents with pain in the neck for 5 days. She is not able to wear tie for her job because of neck pain. H/O fatigue and lethargy for 10 days. She had flu like symptoms 20 days ago which resolved spontaneously. BP 110/80 mmHg, Pulse 48/min. Extremities are cold and dry. Neck is very tender. ECG nor... | Next appropriate step | {
"A": "Atropine injection",
"B": "Levothyroxine administration",
"C": "Aspirin",
"D": "Increase iodine intake in food"
} | C. Aspirin |
cbd91783-e901-4672-9ec1-7f58bce041da | A 74-year-old woman develops occipital headache, vomiting, and dizziness. She looks unwell, her blood pressure is 180/100 mm Hg, pulse is 70/min, and respirations are 30/min. She is unable to sit or walk because of unsteadiness. Over the next few hours, she develops a decline in her level of consciousness.For the above... | basal ganglia hemorrhage | cerebellar hemorrhage | pontine hemorrhage | lobar intracerebral hemorrhage | 1b | multi | Cerebellar hemorrhage, when mild, may present with only headache, vomiting, and ataxia of gait. Patients may complain of dizziness or vertigo. The eyes may be deviated to the side opposite the hemorrhage. Nystagmus is not common, but an ipsilateral sixth nerve palsy can occur. This is the only type of intracerebral hem... | Medicine | C.N.S. | 101 | {
"Correct Answer": "cerebellar hemorrhage",
"Correct Option": "B",
"Options": {
"A": "basal ganglia hemorrhage",
"B": "cerebellar hemorrhage",
"C": "pontine hemorrhage",
"D": "lobar intracerebral hemorrhage"
},
"Question": "A 74-year-old woman develops occipital headache, vomiting, and dizzin... | A 74-year-old woman develops occipital headache, vomiting, and dizziness. She looks unwell, her blood pressure is 180/100 mm Hg, pulse is 70/min, and respirations are 30/min. She is unable to sit or walk because of unsteadiness. | Over the next few hours, she develops a decline in her level of consciousness.For the above patient with altered level of consciousness, select the most likely diagnosis. | {
"A": "basal ganglia hemorrhage",
"B": "cerebellar hemorrhage",
"C": "pontine hemorrhage",
"D": "lobar intracerebral hemorrhage"
} | B. cerebellar hemorrhage |
d5d03cd8-055b-49bf-9b2d-4b8dc3fd6b4d | A 68-year-old man is admitted to the coronary care unit with an acute myocardial infarction. His postinfarction course is marked by congestive hea failure and intermittent hypotension. On the fouh day in hospital, he develops severe midabdominal pain. On physical examination, blood pressure is 90/60 mm Hg and pulse is ... | Barium enema | Upper gastrointestinal series | Angiography | Ultrasonography | 2c | multi | In the absence of peritoneal signs, angiography is the diagnostic test of choice for acute mesenteric ischemia. Patients with peritoneal signs should undergo emergent laparotomy. Acute mesenteric ischemia may be difficult to diagnose. The condition should be suspected in patients with either systemic manifestations of ... | Anaesthesia | Preoperative assessment and monitoring in anaesthesia | 132 | {
"Correct Answer": "Angiography",
"Correct Option": "C",
"Options": {
"A": "Barium enema",
"B": "Upper gastrointestinal series",
"C": "Angiography",
"D": "Ultrasonography"
},
"Question": "A 68-year-old man is admitted to the coronary care unit with an acute myocardial infarction. His postinfa... | A 68-year-old man is admitted to the coronary care unit with an acute myocardial infarction. His postinfarction course is marked by congestive hea failure and intermittent hypotension. On the fouh day in hospital, he develops severe midabdominal pain. On physical examination, blood pressure is 90/60 mm Hg and pulse is ... | Which of the following is the most appropriate next step in this patient's management? | {
"A": "Barium enema",
"B": "Upper gastrointestinal series",
"C": "Angiography",
"D": "Ultrasonography"
} | C. Angiography |
226c17a9-13fe-4496-bc2e-5aabce4fef1c | A 2-week-old baby is irritable and feeding poorly. On physical examination, the infant is irritable, diaphoretic, tachypneic and tachycardic. There is circumoral cyanosis, which is not alleted by nasal oxygen. A systolic thrill and holosystolic murmur are heard along the left sternal border. An echocardiogram reveals a... | Atrial septal defect | Coarctation of aoa, preductal | Patent ductus aeriosus | Truncus aeriosus | 3d | multi | Truncus aeriosus refers to a common trunk for the origin of the aoa, pulmonary aeries and coronary aeries. It results from absent or incomplete paitioning of the truncus aeriosus by the spiral septum during development. Most infants with persistent truncus aeriosus have torrential pulmonary blood flow, which leads to h... | Pathology | Cardiac disorders | 115 | {
"Correct Answer": "Truncus aeriosus",
"Correct Option": "D",
"Options": {
"A": "Atrial septal defect",
"B": "Coarctation of aoa, preductal",
"C": "Patent ductus aeriosus",
"D": "Truncus aeriosus"
},
"Question": "A 2-week-old baby is irritable and feeding poorly. On physical examination, the ... | A 2-week-old baby is irritable and feeding poorly. On physical examination, the infant is irritable, diaphoretic, tachypneic and tachycardic. There is circumoral cyanosis, which is not alleted by nasal oxygen. A systolic thrill and holosystolic murmur are heard along the left sternal border. An echocardiogram reveals a... | What is the appropriate diagnosis? | {
"A": "Atrial septal defect",
"B": "Coarctation of aoa, preductal",
"C": "Patent ductus aeriosus",
"D": "Truncus aeriosus"
} | D. Truncus aeriosus |
66cb240a-b8a0-402c-9a9f-1e0a0ffe3551 | A 44-year-old businessman presents to a physician because of a markedly inflammed and painful right great toe. He states that he just returned from a convention, and had noticed increasing pain in his right foot during his flight back home. Physical examination is remarkable for swelling and erythema of the right great... | Allopurinol | Aspirin | Colchicine | Probenecid | 2c | multi | The patient has gout, which is due to precipitation of monosodium urate crystals in joint spaces (notably the great toe) and soft tissues (causing tophi, which are often found on the external ears). Colchicine reduces the inflammation caused by the urate crystals by inhibiting leukocyte migration and phagocytosis secon... | Pharmacology | null | 119 | {
"Correct Answer": "Colchicine",
"Correct Option": "C",
"Options": {
"A": "Allopurinol",
"B": "Aspirin",
"C": "Colchicine",
"D": "Probenecid"
},
"Question": "A 44-year-old businessman presents to a physician because of a markedly inflammed and painful right great toe. He states that he just r... | A 44-year-old businessman presents to a physician because of a markedly inflammed and painful right great toe. He states that he just returned from a convention, and had noticed increasing pain in his right foot during his flight back home. Physical examination is remarkable for swelling and erythema of the right great... | Which of the following agents would provide the most immediate relief for this patient? | {
"A": "Allopurinol",
"B": "Aspirin",
"C": "Colchicine",
"D": "Probenecid"
} | C. Colchicine |
9ec100e0-c6b0-4164-b3c6-a2685e2a4cd3 | A 4-month-old infant has undergone surgical treatment for meningomyeloencephalocele. At bih, an operation was carried out in the posterior cranial fossa to paially replace brain cerebellar contents to an intracranial position. In investigations for progressive hydrocephalus, it is noted that there is herniation of the ... | Fusion of the frontal lobes | Fusion of the temporal, parietal, and occipital lobes | Abnormal elongation of the medulla and lower cranial nerves | Paial or complete absence of the pituitary gland | 2c | multi | Abnormal elongation of the medulla and lower cranial nerves may be evident in Arnold-Chiari syndrome. Additional features include fusion of the corpora quadrigemina, leading to a "beaked" tectum; paial or complete absence of the corpus callosum; and microgyria. | Surgery | Cerebrovascular Diseases | 105 | {
"Correct Answer": "Abnormal elongation of the medulla and lower cranial nerves",
"Correct Option": "C",
"Options": {
"A": "Fusion of the frontal lobes",
"B": "Fusion of the temporal, parietal, and occipital lobes",
"C": "Abnormal elongation of the medulla and lower cranial nerves",
"D": "Paial o... | A 4-month-old infant has undergone surgical treatment for meningomyeloencephalocele. At bih, an operation was carried out in the posterior cranial fossa to paially replace brain cerebellar contents to an intracranial position. In investigations for progressive hydrocephalus, it is noted that there is herniation of the ... | This syndrome may also include which of the following? | {
"A": "Fusion of the frontal lobes",
"B": "Fusion of the temporal, parietal, and occipital lobes",
"C": "Abnormal elongation of the medulla and lower cranial nerves",
"D": "Paial or complete absence of the pituitary gland"
} | C. Abnormal elongation of the medulla and lower cranial nerves |
c2c522e9-595e-4327-a763-7eb93c7fcb88 | A 68-year-old male is brought to the outpatient by his wife due to increasing forgetfulness. On taking history in details, wife repoed that for around 6 months patient is having trouble in organising the finances and paying bills, something he has done all his life. He has also become withdrawn and has decreased meetin... | Alzheimer disease | Creutzfeldt-Jakob disease | Dementia with Lewy bodies | Frontotemporal dementia | 3d | multi | The history is suggestive of executive dysfunction (trouble in organising the finances and paying bills), apathy and disinhibition (decreased socialisation and inappropriate behaviour with women), lack of insight (denies having any problem) and memory disturbances. This is suggestive of frontotemporal dementia, in whic... | Psychiatry | Organic Mental Disorders | 154 | {
"Correct Answer": "Frontotemporal dementia",
"Correct Option": "D",
"Options": {
"A": "Alzheimer disease",
"B": "Creutzfeldt-Jakob disease",
"C": "Dementia with Lewy bodies",
"D": "Frontotemporal dementia"
},
"Question": "A 68-year-old male is brought to the outpatient by his wife due to inc... | A 68-year-old male is brought to the outpatient by his wife due to increasing forgetfulness. On taking history in details, wife repoed that for around 6 months patient is having trouble in organising the finances and paying bills, something he has done all his life. He has also become withdrawn and has decreased meetin... | Which of the following is the most likely diagnosis? | {
"A": "Alzheimer disease",
"B": "Creutzfeldt-Jakob disease",
"C": "Dementia with Lewy bodies",
"D": "Frontotemporal dementia"
} | D. Frontotemporal dementia |
6459cbf2-9cb5-4d04-bfc3-f75278df9306 | A 10-year-old male child with sho stature presented to the pediatric OPD with complaints of frequent headaches over the past 6 months along with slowly progressive loss of vision of the right eye. Lately the child has also staed having trouble in walking along with frequent mood changes and excessive thirst. MRI brain ... | Hepatocellular carcinoma | Melanoma | Neuroblastoma | CML | 0a | multi | This is a case of Craniopharyngioma. Benign tumour Arise in sellar/suprasellar region Arise from vestigial remnants of Rathke's pouch Bimodal age distribution Presents with headache and visual disturbance May present with sho stature due to GH deficiency (Pituitary hypofunction). Most commonly due to abnormalities in W... | Unknown | Integrated QBank | 128 | {
"Correct Answer": "Hepatocellular carcinoma",
"Correct Option": "A",
"Options": {
"A": "Hepatocellular carcinoma",
"B": "Melanoma",
"C": "Neuroblastoma",
"D": "CML"
},
"Question": "A 10-year-old male child with sho stature presented to the pediatric OPD with complaints of frequent headaches ... | A 10-year-old male child with sho stature presented to the pediatric OPD with complaints of frequent headaches over the past 6 months along with slowly progressive loss of vision of the right eye. Lately the child has also staed having trouble in walking along with frequent mood changes and excessive thirst. MRI brain ... | The gene involved in causing the above condition is also involved in causing which other condition: - | {
"A": "Hepatocellular carcinoma",
"B": "Melanoma",
"C": "Neuroblastoma",
"D": "CML"
} | A. Hepatocellular carcinoma |
76c1bec9-32e2-4a59-94e6-bb791855bec6 | A 40-year-old intravenous drug user presents to the emergency depament with a 2 days history of right knee pain with associated swelling and erythema. The patient is febrile with a holosystolic murmur at the right lower sternal border. Complete blood count reveals leukocytosis. Blood and synol fluid cultures are sent, ... | Neisseria gonorrhoeae | Pseudomonas aeruginosa | Borrelia burgdorferi | Staphylococcus aureus | 3d | single | Gram-positive bacteria remain the most common cause of septic ahritis. Staphylococcus aureus accounts for the majority of culture-positive septic ahritis, especially within ceain patient subgroups such as hemodialysis patients and intravenous drug abusers. The predominance of S. aureus in septic ahritis has remained un... | Orthopaedics | Thigh, Knee,Leg,Foot & Ankle injuries | 101 | {
"Correct Answer": "Staphylococcus aureus",
"Correct Option": "D",
"Options": {
"A": "Neisseria gonorrhoeae",
"B": "Pseudomonas aeruginosa",
"C": "Borrelia burgdorferi",
"D": "Staphylococcus aureus"
},
"Question": "A 40-year-old intravenous drug user presents to the emergency depament with a ... | A 40-year-old intravenous drug user presents to the emergency depament with a 2 days history of right knee pain with associated swelling and erythema. The patient is febrile with a holosystolic murmur at the right lower sternal border. Complete blood count reveals leukocytosis. Blood and synol fluid cultures are sent, ... | What is the most likely pathogen causing these symptoms | {
"A": "Neisseria gonorrhoeae",
"B": "Pseudomonas aeruginosa",
"C": "Borrelia burgdorferi",
"D": "Staphylococcus aureus"
} | D. Staphylococcus aureus |
daf61c69-6951-485c-b98e-5e85aa3c5120 | A 25 years old female complains of recurrent rhinitis, nasal discharge and bilateral nasal blockage since one year. She has the history of asthma and allergy. On examination, multiple ethmoidal polyps are noted with mucosal thickening and impacted secretions in both the nasal cavities. A biopsy is taken and the materia... | Aspergillus fumigatus | Rhizopus | Mucor | Candida | 0a | multi | Aspergillus shows typical dichotomous branching at an angle of approximately 45degrees. Candida shows pseudohyphae. Rhizopus and mucor shows nonseptate hyphae. Reference: Textbook of Microbiology; Baveja; 4th edition | Microbiology | mycology | 108 | {
"Correct Answer": "Aspergillus fumigatus",
"Correct Option": "A",
"Options": {
"A": "Aspergillus fumigatus",
"B": "Rhizopus",
"C": "Mucor",
"D": "Candida"
},
"Question": "A 25 years old female complains of recurrent rhinitis, nasal discharge and bilateral nasal blockage since one year. She h... | A 25 years old female complains of recurrent rhinitis, nasal discharge and bilateral nasal blockage since one year. She has the history of asthma and allergy. On examination, multiple ethmoidal polyps are noted with mucosal thickening and impacted secretions in both the nasal cavities. A biopsy is taken and the materia... | Which of the following is the most likely responsible organism | {
"A": "Aspergillus fumigatus",
"B": "Rhizopus",
"C": "Mucor",
"D": "Candida"
} | A. Aspergillus fumigatus |
fb22bfc1-6edc-4099-9d59-5ab1aec761e2 | Ten days after an exploratory laparotomy and lysis of adhesions, a patient, who previously underwent a low anterior resection for rectal cancer followed by postoperative chemoradiation, is noted to have succus draining from the wound. She appears to have adequate source control--she is afebrile with a normal white bloo... | Previous radiation | Previous chemotherapy | Recent surgery | History of malignancy | 0a | single | Factors that predispose to fistula formation and may prevent closure include foreign body, radiation, inflammation, epithelialization of the tract, neoplasm, distal obstruction, and steroids.Factors that result in unhealthy or abnormal tissue surrounding the enterocutaneous fistula decrease the likelihood of spontaneou... | Anaesthesia | Preoperative assessment and monitoring in anaesthesia | 110 | {
"Correct Answer": "Previous radiation",
"Correct Option": "A",
"Options": {
"A": "Previous radiation",
"B": "Previous chemotherapy",
"C": "Recent surgery",
"D": "History of malignancy"
},
"Question": "Ten days after an exploratory laparotomy and lysis of adhesions, a patient, who previously ... | Ten days after an exploratory laparotomy and lysis of adhesions, a patient, who previously underwent a low anterior resection for rectal cancer followed by postoperative chemoradiation, is noted to have succus draining from the wound. She appears to have adequate source control--she is afebrile with a normal white bloo... | Which of the following factors is most likely to prevent closure of the enterocutaneous fistula? | {
"A": "Previous radiation",
"B": "Previous chemotherapy",
"C": "Recent surgery",
"D": "History of malignancy"
} | A. Previous radiation |
f8d1aab7-88d9-4a6a-982d-8f8ad20ddd8a | A 33-year-old male immigrant from Taiwan presents with increasing right upper quadrant (RUQ) pain. The pain is dull, and it does not radiate or change with eating. On examination the abdomen is soft, there is a mass in the RUQ, and no ascites is clinically detected. He has a prior history of hepatitis B. His laboratory... | hepatoma | hepatocellular carcinoma (HCC) | metastatic cancer | hepatic hemangioma | 1b | multi | (b) Source: (Devita, pp. 533-534) Only the chronic carrier state increases HCC risk, not previous infection. The majority, but not all, of HCC associated with HBV occurs in the setting of cirrhosis (60-90%). Because the latency period of HBV infection is 35 years, before HCC supervenes, early-life infection is strongly... | Medicine | Oncology | 147 | {
"Correct Answer": "hepatocellular carcinoma (HCC)",
"Correct Option": "B",
"Options": {
"A": "hepatoma",
"B": "hepatocellular carcinoma (HCC)",
"C": "metastatic cancer",
"D": "hepatic hemangioma"
},
"Question": "A 33-year-old male immigrant from Taiwan presents with increasing right upper qu... | A 33-year-old male immigrant from Taiwan presents with increasing right upper quadrant (RUQ) pain. The pain is dull, and it does not radiate or change with eating. On examination the abdomen is soft, there is a mass in the RUQ, and no ascites is clinically detected. He has a prior history of hepatitis B. His laboratory... | Which of the following is the most likely diagnosis? | {
"A": "hepatoma",
"B": "hepatocellular carcinoma (HCC)",
"C": "metastatic cancer",
"D": "hepatic hemangioma"
} | B. hepatocellular carcinoma (HCC) |
8ac9640d-d878-4003-8341-2eea055157f8 | A 60-year-old man presents to the emergency department with chest pain described as retrosternal chest pressure radiating to the jaw. The symptoms started at rest and coming and going, but never lasting more than 15 minutes. He has a prior history of hypertension and smokes 1 pack/day. He is currently chest-pain free a... | IV streptokinase | coronary angiography | exercise testing | oral aspirin | 1b | multi | A period of 24-48 hours is usually allowed to attempt medical therapy. Cardiac catheterization and angiography may be followed by bypass surgery or angioplasty. For those who do settle down, some form of subsequent risk stratification (e.g., exercise ECG) is indicated. | Medicine | C.V.S. | 207 | {
"Correct Answer": "coronary angiography",
"Correct Option": "B",
"Options": {
"A": "IV streptokinase",
"B": "coronary angiography",
"C": "exercise testing",
"D": "oral aspirin"
},
"Question": "A 60-year-old man presents to the emergency department with chest pain described as retrosternal ch... | A 60-year-old man presents to the emergency department with chest pain described as retrosternal chest pressure radiating to the jaw. The symptoms started at rest and coming and going, but never lasting more than 15 minutes. He has a prior history of hypertension and smokes 1 pack/day. He is currently chest-pain free a... | Which of the following is the most appropriate next step in management? | {
"A": "IV streptokinase",
"B": "coronary angiography",
"C": "exercise testing",
"D": "oral aspirin"
} | B. coronary angiography |
9dbfe50d-9f1b-40f7-9d22-086482e85b07 | A child is taken to a pediatrician because his mother notices that his eyes appear very puffy. The mother said that the boy's eyes appeared normal two days ago, and pa of what caused her concern was that her child seemed to be rapidly becoming ill. On physical examination, the boy is noted to have generalized edema. No... | Acute renal failure | Chronic renal failure | Lower urinary tract disease | Nephrotic syndrome | 3d | multi | Proteinuria greater than 40 mg/h/m2 in a child or 3.5 g/d/1.73 m2 in an adult produces nephrotic syndrome, which is characterized by generalized edema, often most noticeable in the face. The condition develops when large amounts of protein are spilled through the glomeruli into the duct system of the kidneys. In contra... | Pediatrics | null | 173 | {
"Correct Answer": "Nephrotic syndrome",
"Correct Option": "D",
"Options": {
"A": "Acute renal failure",
"B": "Chronic renal failure",
"C": "Lower urinary tract disease",
"D": "Nephrotic syndrome"
},
"Question": "A child is taken to a pediatrician because his mother notices that his eyes appe... | A child is taken to a pediatrician because his mother notices that his eyes appear very puffy. The mother said that the boy's eyes appeared normal two days ago, and pa of what caused her concern was that her child seemed to be rapidly becoming ill. On physical examination, the boy is noted to have generalized edema. No... | Which of the following is the most likely diagnosis? | {
"A": "Acute renal failure",
"B": "Chronic renal failure",
"C": "Lower urinary tract disease",
"D": "Nephrotic syndrome"
} | D. Nephrotic syndrome |
4db14beb-81b4-4ff3-a091-adf901ae0570 | A 44-year-old renal transplant patient develops severe cough and shortness of breath on exertion. On examination, he appears dyspneic, respirations 24/min, pulse 110/min, and oxygen saturation 88%. His lungs are clear on auscultation and heart sounds are normal. CXR shows bilateral diffuse perihilar infiltrates. Bronch... | amphotericin B | cephalosporins | trimethoprim-sulfamethoxazole | aminoglycosides | 2c | multi | The patient is infected with Pneumocystis organisms invading an immunocompromised host. The treatment of choice is trimethoprim-sulfamethoxazole. Alternate therapies include pentamidine (highly toxic) and trimetrexate plus folinic acid. | Medicine | Infection | 113 | {
"Correct Answer": "trimethoprim-sulfamethoxazole",
"Correct Option": "C",
"Options": {
"A": "amphotericin B",
"B": "cephalosporins",
"C": "trimethoprim-sulfamethoxazole",
"D": "aminoglycosides"
},
"Question": "A 44-year-old renal transplant patient develops severe cough and shortness of brea... | A 44-year-old renal transplant patient develops severe cough and shortness of breath on exertion. On examination, he appears dyspneic, respirations 24/min, pulse 110/min, and oxygen saturation 88%. His lungs are clear on auscultation and heart sounds are normal. CXR shows bilateral diffuse perihilar infiltrates. Bronch... | Which of the following is the most appropriate next step in management? | {
"A": "amphotericin B",
"B": "cephalosporins",
"C": "trimethoprim-sulfamethoxazole",
"D": "aminoglycosides"
} | C. trimethoprim-sulfamethoxazole |
079d565e-2a47-4500-96af-30bb792d8137 | An 8-month-old child presented with reduced appetite, abdominal distension and pain and psychomotor retardation. The child was normal at bih and both parents are normal. O/E: - Hepatosplenomegaly Moderate lymphadenopathy Abnormal posturing of the limbs, trunk, and face Impaired voluntary rapid eye movements Cheery red ... | Hexosaminidase A | Alpha-galactosidase A | Glucocerebrosidase | Sphingomyelinase | 3d | multi | This is a case of Niemann-pick disease. 1. Autosomal recessive disease 2. Divided into 2 groups depending on deficiency: - Deficiency of acid sphingomyelinase enzyme- Type A and B Impaired intracellular cholesterol trafficking- Type C and D 3. Normal at bih 4. Presents with hepatosplenomegaly, lymphadenopathy and cherr... | Unknown | Integrated QBank | 109 | {
"Correct Answer": "Sphingomyelinase",
"Correct Option": "D",
"Options": {
"A": "Hexosaminidase A",
"B": "Alpha-galactosidase A",
"C": "Glucocerebrosidase",
"D": "Sphingomyelinase"
},
"Question": "An 8-month-old child presented with reduced appetite, abdominal distension and pain and psychomo... | An 8-month-old child presented with reduced appetite, abdominal distension and pain and psychomotor retardation. The child was normal at bih and both parents are normal. O/E: - Hepatosplenomegaly Moderate lymphadenopathy Abnormal posturing of the limbs, trunk, and face Impaired voluntary rapid eye movements Cheery red ... | EM findings Which of the following enzymes is most likely deficient in the above disease: - | {
"A": "Hexosaminidase A",
"B": "Alpha-galactosidase A",
"C": "Glucocerebrosidase",
"D": "Sphingomyelinase"
} | D. Sphingomyelinase |
a19c7974-94c0-4955-8fd7-fd4117ba4f46 | An elderly house wife lost her husband who died suddenly of Myocardial infarction couple of years ago. They had been staying alone for almost a decade with infrequent visits from her son and grandchildren. About a week after the death she heard his voice clearly talking to her as he would in a routine manner from the n... | Clornipramine. | Aiprazolam | Electroconvulsive therapy. | Haloperidol. | 3d | single | D i.e. HaloperidolThe diagnosis of this lady is morbid grief When there is an exaggeration of one or more symptoms of normal grief or the duration becomes prolonged beyond 6 months without recovery, it is k/a morbid grief.Preoccupation with the memory of deceased is a characteristic featureQ.Idealization of deceased (i... | Psychiatry | null | 122 | {
"Correct Answer": "Haloperidol.",
"Correct Option": "D",
"Options": {
"A": "Clornipramine.",
"B": "Aiprazolam",
"C": "Electroconvulsive therapy.",
"D": "Haloperidol."
},
"Question": "An elderly house wife lost her husband who died suddenly of Myocardial infarction couple of years ago. They h... | An elderly house wife lost her husband who died suddenly of Myocardial infarction couple of years ago. They had been staying alone for almost a decade with infrequent visits from her son and grandchildren. About a week after the death she heard his voice clearly talking to her as he would in a routine manner from the n... | She should be treated with: | {
"A": "Clornipramine.",
"B": "Aiprazolam",
"C": "Electroconvulsive therapy.",
"D": "Haloperidol."
} | D. Haloperidol. |
cc40d3a2-ae63-4c4f-aa83-32d663267e66 | A 50-year-old woman presents with easy fatigability, a smooth sore tongue, numbness and tingling of the feet, and weakness of the legs. A complete blood count shows a megaloblastic anemia that is not reversed by folate therapy. Hemoglobin is 5.6 g/dL, WBC count is 5,100/mL, and platelets are 240,000/mL. This patient mo... | Vitamin B1 (thiamine) | Vitamin B2 (riboflavin) | Vitamin B12 | Vitamin K | 2c | single | Except for a few rare situations, vitamin B12 (cyanocobalamin) deficiency is usually a result of pernicious anemia, an autoimmune disease of the stomach. Vitamin B12 is required for DNA synthesis, and its deficiency results in large (megaloblastic) nuclei.Diagnosis: Vitamin B12 deficiency, pernicious anemia | Pathology | Environment & Nutritional Pathology | 107 | {
"Correct Answer": "Vitamin B12",
"Correct Option": "C",
"Options": {
"A": "Vitamin B1 (thiamine)",
"B": "Vitamin B2 (riboflavin)",
"C": "Vitamin B12",
"D": "Vitamin K"
},
"Question": "A 50-year-old woman presents with easy fatigability, a smooth sore tongue, numbness and tingling of the feet... | A 50-year-old woman presents with easy fatigability, a smooth sore tongue, numbness and tingling of the feet, and weakness of the legs. A complete blood count shows a megaloblastic anemia that is not reversed by folate therapy. Hemoglobin is 5.6 g/dL, WBC count is 5,100/mL, and platelets are 240,000/mL. | This patient most likely has a deficiency of which of the following vitamins? | {
"A": "Vitamin B1 (thiamine)",
"B": "Vitamin B2 (riboflavin)",
"C": "Vitamin B12",
"D": "Vitamin K"
} | C. Vitamin B12 |
b226c32d-02b3-4626-92d3-0aada5d3782b | A 25-year-old woman with amenorrhea has never had menarche. On physical examination, she is 145 cm (4 ft 9 in) tall. She has a webbed neck, a broad chest, and widely spaced nipples. Strong pulses are palpable in the upper extremities, but there are only weak pulses in the lower extremities. On abdominal MR imaging, her... | 45, X/46, XX | 46, X, X (fra) | 47, XXY | 47, XXX | 0a | multi | The features described are those of classic Turner syndrome. Individuals who reach adulthood may have mosaic cell lines, with some 45, X cells and some 46, XX cells. A female carrier of the fragile X syndrome, X(fra), is less likely to manifest the disease than a male, but the number of triple repeat sequences (CGG) in... | Pathology | Genetics | 110 | {
"Correct Answer": "45, X/46, XX",
"Correct Option": "A",
"Options": {
"A": "45, X/46, XX",
"B": "46, X, X (fra)",
"C": "47, XXY",
"D": "47, XXX"
},
"Question": "A 25-year-old woman with amenorrhea has never had menarche. On physical examination, she is 145 cm (4 ft 9 in) tall. She has a webb... | A 25-year-old woman with amenorrhea has never had menarche. On physical examination, she is 145 cm (4 ft 9 in) tall. She has a webbed neck, a broad chest, and widely spaced nipples. Strong pulses are palpable in the upper extremities, but there are only weak pulses in the lower extremities. On abdominal MR imaging, her... | Which of the following karyotypes is she most likely to have? | {
"A": "45, X/46, XX",
"B": "46, X, X (fra)",
"C": "47, XXY",
"D": "47, XXX"
} | A. 45, X/46, XX |
05f44b18-2b84-47dc-8607-869781e0559b | A 78-year-old woman has an acute anterior wall MI with hypotension and pulmonary congestion. Her blood pressure is 90/70 mm Hg, pulse 110/min, JVP at 8 cm, and the heart sounds are normal. The lungs have bibasilar crackles, and her extremities are cool and diaphoretic. What would central hemodynamic monitoring reveal?F... | decreased right atrial pressure (RAP), low cardiac output (CO), and increased systemic vascular resistance (SVR) | increased RAP, decreased CO, increased SVR | increased RAP, decreased CO, decreased SVR | decreased RAP, increased CO, decreased SVR | 1b | multi | Cardiogenic shock is characterized by high right atrial pressure (although it can be normal at times), high PA wedge pressure, high systemic vascular resistance, and low cardiac output. | Medicine | C.V.S. | 103 | {
"Correct Answer": "increased RAP, decreased CO, increased SVR",
"Correct Option": "B",
"Options": {
"A": "decreased right atrial pressure (RAP), low cardiac output (CO), and increased systemic vascular resistance (SVR)",
"B": "increased RAP, decreased CO, increased SVR",
"C": "increased RAP, decreas... | A 78-year-old woman has an acute anterior wall MI with hypotension and pulmonary congestion. Her blood pressure is 90/70 mm Hg, pulse 110/min, JVP at 8 cm, and the heart sounds are normal. The lungs have bibasilar crackles, and her extremities are cool and diaphoretic. | What would central hemodynamic monitoring reveal?For the above patient, select the hemodynamic parameters that are most likely to apply. | {
"A": "decreased right atrial pressure (RAP), low cardiac output (CO), and increased systemic vascular resistance (SVR)",
"B": "increased RAP, decreased CO, increased SVR",
"C": "increased RAP, decreased CO, decreased SVR",
"D": "decreased RAP, increased CO, decreased SVR"
} | B. increased RAP, decreased CO, increased SVR |
ddb2fe1c-105e-4ccf-a740-fe383571d102 | A 30 year old male was brought for evaluation. The history revealed that the patients 3 year old son died, 5 months back after being hit by a car. At the time of accident, patient was standing nearby and witnessed the accident. For last 5 months, he has been having symptoms of sadness of mood, crying spells, feelings o... | Post traumatic stress disorder | Normal grief | Major depression | Adjustment disorder | 2c | single | Depression: A major depressive disorder occurs without a history of a manic, mixed, or hypomanic episode. A major depressive episode must last at least 2 weeks DIAGNOSIS: Major Depressive Disorder The DSM-5 diagnostic criteria for major depression Sadness of mood Diminished interest in pleasure Significant weight loss ... | Psychiatry | Schizophrenia Spectrum and Other Psychotic Disorders | 116 | {
"Correct Answer": "Major depression",
"Correct Option": "C",
"Options": {
"A": "Post traumatic stress disorder",
"B": "Normal grief",
"C": "Major depression",
"D": "Adjustment disorder"
},
"Question": "A 30 year old male was brought for evaluation. The history revealed that the patients 3 ye... | A 30 year old male was brought for evaluation. The history revealed that the patients 3 year old son died, 5 months back after being hit by a car. At the time of accident, patient was standing nearby and witnessed the accident. For last 5 months, he has been having symptoms of sadness of mood, crying spells, feelings o... | What is the likely diagnosis: | {
"A": "Post traumatic stress disorder",
"B": "Normal grief",
"C": "Major depression",
"D": "Adjustment disorder"
} | C. Major depression |
071b822d-0b92-4499-bfa3-710331047cae | A 23-year-old female maid was making a bed in a hotel bedroom. As she straightened the sheet by running her right hand over the surface with her fingers extended, she caught the end of the index finger in a fold. She experienced a sudden, severe pain over the base of the terminal phalanx. Several hours later when the p... | The proper palmar digital branch of the median nerve | The vinculum longa | The insertion of the tendon of the extensor digitorum onto the base of the distal phalanx | The insertion of the flexor digitorum profundus tendon | 2c | single | The contraction of the extensor mechanism produces extension of the distal interphalangeal joint. When it is torn from the distal phalanx, the digit is pulled into flexion by the flexor digitorum profundus. The proper palmar digital branches of the median nerve supply lumbrical muscles and carry sensation from their re... | Anatomy | Upper Extremity | 116 | {
"Correct Answer": "The insertion of the tendon of the extensor digitorum onto the base of the distal phalanx",
"Correct Option": "C",
"Options": {
"A": "The proper palmar digital branch of the median nerve",
"B": "The vinculum longa",
"C": "The insertion of the tendon of the extensor digitorum onto ... | A 23-year-old female maid was making a bed in a hotel bedroom. As she straightened the sheet by running her right hand over the surface with her fingers extended, she caught the end of the index finger in a fold. She experienced a sudden, severe pain over the base of the terminal phalanx. Several hours later when the p... | Which one of the following structures within the digit was most likely injured? | {
"A": "The proper palmar digital branch of the median nerve",
"B": "The vinculum longa",
"C": "The insertion of the tendon of the extensor digitorum onto the base of the distal phalanx",
"D": "The insertion of the flexor digitorum profundus tendon"
} | C. The insertion of the tendon of the extensor digitorum onto the base of the distal phalanx |
e4ba25b1-2be8-4d30-b095-c3ddc931cc4c | A 26 year old third_gravida mother delivered a male baby weighing 4-2 kg at 37 weeks of gestation through an emergency caesarean section, for obstructed labour. The child developed respiratory distress one hour after bih. He was kept nil per orally (NPO) and given intravenous fluids. He maintained oxygen saturation on ... | Transient tachypnea of the newborn | Meconium aspiration syndrome | Persistent fetal circulation | Hyaline membrane disease | 0a | multi | Ans. is 'a' i.e., Transient tachypnea of newborn o Respiratory distress, which resolves within 24 hours without any respiratory suppo and fluid in interlobar fissure on chest X-ray suggest the diagnosis of TTN. | Pediatrics | null | 115 | {
"Correct Answer": "Transient tachypnea of the newborn",
"Correct Option": "A",
"Options": {
"A": "Transient tachypnea of the newborn",
"B": "Meconium aspiration syndrome",
"C": "Persistent fetal circulation",
"D": "Hyaline membrane disease"
},
"Question": "A 26 year old third_gravida mother ... | A 26 year old third_gravida mother delivered a male baby weighing 4-2 kg at 37 weeks of gestation through an emergency caesarean section, for obstructed labour. The child developed respiratory distress one hour after bih. He was kept nil per orally (NPO) and given intravenous fluids. He maintained oxygen saturation on ... | What is the most likely diagnosis ? | {
"A": "Transient tachypnea of the newborn",
"B": "Meconium aspiration syndrome",
"C": "Persistent fetal circulation",
"D": "Hyaline membrane disease"
} | A. Transient tachypnea of the newborn |
d93522e3-8ae1-451e-a688-daec2e5dfe08 | A 19-year-old man presents to the clinic complaining of early fatigue and muscle cramps while playing sports. He is fine when walking or doing less intense levels of work. On physical examination, he appears well and the vital signs are normal. Muscle bulk, tone and strength in the proximal muscles are normal. There is... | Gaucher disease | Tay-Sachs disease | McArdle disease (glycogen storage disease) | hemochromatosis | 2c | single | There are many types of glycogen storage diseases, each caused by a different enzymatic abnormality. The best-known types of glycogen storage disease are those that have hepatic hypoglycemic pathophysiology (eg, von Gierke disease) or those that have muscle energy pathophysiology (McArdle disease). InMcArdle' symptoms ... | Medicine | Endocrinology | 109 | {
"Correct Answer": "McArdle disease (glycogen storage disease)",
"Correct Option": "C",
"Options": {
"A": "Gaucher disease",
"B": "Tay-Sachs disease",
"C": "McArdle disease (glycogen storage disease)",
"D": "hemochromatosis"
},
"Question": "A 19-year-old man presents to the clinic complaining... | A 19-year-old man presents to the clinic complaining of early fatigue and muscle cramps while playing sports. He is fine when walking or doing less intense levels of work. On physical examination, he appears well and the vital signs are normal. Muscle bulk, tone and strength in the proximal muscles are normal. There is... | Which of the following is the most likely diagnosis? | {
"A": "Gaucher disease",
"B": "Tay-Sachs disease",
"C": "McArdle disease (glycogen storage disease)",
"D": "hemochromatosis"
} | C. McArdle disease (glycogen storage disease) |
819a9b25-36f0-41d0-a409-8289d976f067 | Kamli Rani, 75-years -old woman present with post myocardial infarction after 6 weeks mild CHF. There was past H/O neck surgery for parathyroid adenoma 5 years ago, ECG shows slow atrial fibrillation. Serum Ca2+ 13.0 mg/L and urinary Ca2+ is 300 mg/24 hr. On examination there is small mass in the Para tracheal position... | Repeat neck surgery | Treatment with technetium-99 | Observation and repeat serum Ca2+ in two months | Ultrasound-guided alcohol injection of the mass | 3d | multi | Patient is a case of recurrent hyperparathyroidism, as she was operated previously for parathyroid adenoma. In the setting of recent myocardial infarction, CHF and atrial fibrillation, any operation carries a high risk. Ultrasound-guided alcohol injection in the mass is preferred in this setting. | Surgery | Parathyroid and adrenal glands | 112 | {
"Correct Answer": "Ultrasound-guided alcohol injection of the mass",
"Correct Option": "D",
"Options": {
"A": "Repeat neck surgery",
"B": "Treatment with technetium-99",
"C": "Observation and repeat serum Ca2+ in two months",
"D": "Ultrasound-guided alcohol injection of the mass"
},
"Questio... | Kamli Rani, 75-years -old woman present with post myocardial infarction after 6 weeks mild CHF. There was past H/O neck surgery for parathyroid adenoma 5 years ago, ECG shows slow atrial fibrillation. Serum Ca2+ 13.0 mg/L and urinary Ca2+ is 300 mg/24 hr. On examination there is small mass in the Para tracheal position... | Appropriate management at this time is: | {
"A": "Repeat neck surgery",
"B": "Treatment with technetium-99",
"C": "Observation and repeat serum Ca2+ in two months",
"D": "Ultrasound-guided alcohol injection of the mass"
} | D. Ultrasound-guided alcohol injection of the mass |
c7adea89-80f3-4715-950a-4b0b133f8e84 | A 57-year-old man arrives at the emergency room complaining of weakness, fatigue, and intermittent fever that has recurred for several weeks. The patient had a cardiac valvular prosthesis implanted 5 years ago. Blood cultures grew ceain gram-positive cocci on which catalase and coagulase test were done. The gram-positi... | Staphylococcus aureus | Staphylococcus epidermidis | Staphylococcus saprophyticus | Streptococcus viridans | 1b | single | Physical examination reveals petechiae (pinpoint, nonraised, purplish red spots caused by intradermal hemorrhage) on the chest and stomach. Catalase-positive and coagulase negative The patient is probably suffering from bacterial endocarditis caused by S. epidermidis infection of the prosthetic hea valve. S. epidermidi... | Unknown | Integrated QBank | 113 | {
"Correct Answer": "Staphylococcus epidermidis",
"Correct Option": "B",
"Options": {
"A": "Staphylococcus aureus",
"B": "Staphylococcus epidermidis",
"C": "Staphylococcus saprophyticus",
"D": "Streptococcus viridans"
},
"Question": "A 57-year-old man arrives at the emergency room complaining ... | A 57-year-old man arrives at the emergency room complaining of weakness, fatigue, and intermittent fever that has recurred for several weeks. The patient had a cardiac valvular prosthesis implanted 5 years ago. Blood cultures grew ceain gram-positive cocci on which catalase and coagulase test were done. The gram-positi... | CATALASE TEST SLIDE COAGULASE TEST Lesions seen on skin What is the most likely infectious agent? | {
"A": "Staphylococcus aureus",
"B": "Staphylococcus epidermidis",
"C": "Staphylococcus saprophyticus",
"D": "Streptococcus viridans"
} | B. Staphylococcus epidermidis |
91d5cae7-c4a1-4d69-b76a-5fd898c29f51 | A 4-year-old child presented with palpable purpura and polyahralgia without any frank ahritis along with colicky abdominal pain associated with nausea, vomiting, diarrhea and the passage of blood and mucus per rectum. Urine examination revealed proteinuria and microscopic haematuria. Laboratory studies revealed mild le... | Clotting disorder | Septic emboli | HSP | Uicarial vasculitis | 2c | single | Perivascular neutrophils, leukocytoclasis and fibrinoid degeneration involving the small dermal blood vessels with subsequent hemorrhage in a skin biopsy of a patient with HSP. Skin biopsy showing positive immunofluorescence of the small blood vessels for IgA. Henoch-Schonlein purpura (HSP) Acute immunoglobulin A (IgA)... | Anatomy | Integrated QBank | 104 | {
"Correct Answer": "HSP",
"Correct Option": "C",
"Options": {
"A": "Clotting disorder",
"B": "Septic emboli",
"C": "HSP",
"D": "Uicarial vasculitis"
},
"Question": "A 4-year-old child presented with palpable purpura and polyahralgia without any frank ahritis along with colicky abdominal pain ... | A 4-year-old child presented with palpable purpura and polyahralgia without any frank ahritis along with colicky abdominal pain associated with nausea, vomiting, diarrhea and the passage of blood and mucus per rectum. Urine examination revealed proteinuria and microscopic haematuria. Laboratory studies revealed mild le... | Skin biopsy specimen was taken. | {
"A": "Clotting disorder",
"B": "Septic emboli",
"C": "HSP",
"D": "Uicarial vasculitis"
} | C. HSP |
0df537bb-a632-489f-ad81-622b19a6b4c1 | A 52-year-old man presents to the eye clinic with painless vision loss of his right eye. He describes the visual loss as a gradual progression from blurry to total blackout over the past two hours. He has no history of prior visual problems. Past medical history is significant for a myocardial infarction three years ag... | 11-cis-retinal | All-cis-retinal | All-trans-retinal | Meta-rhodopsin ll | 0a | multi | The visual cascade: 11-cis-retinal + opsin -> rhodopsin + light -> meta-rhodopsin II. Meta-rhodopsin II dissociates after light exposure to form all-trans-retinal. 11-cis retinal and opsin are essential first steps in generating the photochemical visual cascade. All-cis-retinal is not a pa of the visual cascade. All-tr... | Ophthalmology | null | 152 | {
"Correct Answer": "11-cis-retinal",
"Correct Option": "A",
"Options": {
"A": "11-cis-retinal",
"B": "All-cis-retinal",
"C": "All-trans-retinal",
"D": "Meta-rhodopsin ll"
},
"Question": "A 52-year-old man presents to the eye clinic with painless vision loss of his right eye. He describes the ... | A 52-year-old man presents to the eye clinic with painless vision loss of his right eye. He describes the visual loss as a gradual progression from blurry to total blackout over the past two hours. He has no history of prior visual problems. Past medical history is significant for a myocardial infarction three years ag... | At the molecular level, which of the following components is essential for the first step of the visual cascade? | {
"A": "11-cis-retinal",
"B": "All-cis-retinal",
"C": "All-trans-retinal",
"D": "Meta-rhodopsin ll"
} | A. 11-cis-retinal |
6bce4733-0e59-4afe-baf4-c159a236caca | Hemoglobin is isolated from the erythrocytes of a young child with anemia. Hemoglobin electrophoresis reveals the presence of an unstable hemoglobin, known as hemoglobin Cranston (HbCr), containing an abnormal b-globin chain. The normal sequence of the b-globin gene (HbNl) and the sequence of the HbCr b-chain are prese... | A frameshift mutation resulted in the deletion of several amino acid residues in the b-chain | A mutation in the stop codon resulted in elongation of the b-chain | A point mutation resulted in the inseion of a stop codon in the b-chain | A two base pair addition resulted in the elimination of a stop codon in the b-chain | 3d | single | Looking at the coding segment of the normal b-gene of hemoglobin, one should read the information codon by codon, as follows: AAG UAU CAC UAA GCU CGC 1 2 3 4 5 6 The normal b-globin gene has a stop codon (UAA) at the 4th position, therefore the last 2 codons (GCU and CGC) are not translated and do not code for amino ac... | Biochemistry | null | 140 | {
"Correct Answer": "A two base pair addition resulted in the elimination of a stop codon in the b-chain",
"Correct Option": "D",
"Options": {
"A": "A frameshift mutation resulted in the deletion of several amino acid residues in the b-chain",
"B": "A mutation in the stop codon resulted in elongation of t... | Hemoglobin is isolated from the erythrocytes of a young child with anemia. Hemoglobin electrophoresis reveals the presence of an unstable hemoglobin, known as hemoglobin Cranston (HbCr), containing an abnormal b-globin chain. The normal sequence of the b-globin gene (HbNl) and the sequence of the HbCr b-chain are prese... | HbNl: AAGUAUCACUAAGCUCGC HbCr: AAGAGUAUCACUAAGCUCGCUUUC >>> UAU UAA Which of the following would account for the development of HbCr? | {
"A": "A frameshift mutation resulted in the deletion of several amino acid residues in the b-chain",
"B": "A mutation in the stop codon resulted in elongation of the b-chain",
"C": "A point mutation resulted in the inseion of a stop codon in the b-chain",
"D": "A two base pair addition resulted in the elimina... | D. A two base pair addition resulted in the elimination of a stop codon in the b-chain |
2f272bd1-36d2-4982-9bf5-c24136a3552b | A 24-year-old P2+0 woman presents to the emergency department complaining of pain in her right breast. The patient is postpartum day 10 from an uncomplicated spontaneous vaginal delivery at 42 weeks. She reports no difficulty breast-feeding for the first several days postpartum, but states that for the past week her da... | Continue breast feeding from both the breasts | Breastfeed from unaffected breast only | Immediately start antibiotics and breastfeed only when antibiotics are discontinued. | Pump and discard breastmilk till infection is over and then continue breatfedding | 0a | multi | A postpartum lady coming with H/o pain in breast and fever and nipples being warm, red, swollen, with no induration, fluctuance and no pus extruding from them - leaves no doubt that the patient is having mastitis. As discussed in question 9, mastitis is not a contraindication for breast feeding. She should continue fee... | Gynaecology & Obstetrics | null | 153 | {
"Correct Answer": "Continue breast feeding from both the breasts",
"Correct Option": "A",
"Options": {
"A": "Continue breast feeding from both the breasts",
"B": "Breastfeed from unaffected breast only",
"C": "Immediately start antibiotics and breastfeed only when antibiotics are discontinued.",
... | A 24-year-old P2+0 woman presents to the emergency department complaining of pain in her right breast. The patient is postpartum day 10 from an uncomplicated spontaneous vaginal delivery at 42 weeks. She reports no difficulty breast-feeding for the first several days postpartum, but states that for the past week her da... | There is no fluctuance or induration, and no pus can be expressed from the nipple. | {
"A": "Continue breast feeding from both the breasts",
"B": "Breastfeed from unaffected breast only",
"C": "Immediately start antibiotics and breastfeed only when antibiotics are discontinued.",
"D": "Pump and discard breastmilk till infection is over and then continue breatfedding"
} | A. Continue breast feeding from both the breasts |
a21b7844-9dae-4ab5-a61e-ab3da03efa83 | A 57-year-old man presents with hemoptysis and generalized weakness. His symptoms began with small-volume hemoptysis 4 weeks ago. Over the past 2 weeks, he has become weak and feels "out of it." His appetite has diminished, and he has lost 10 lb of weight. He has a 45-pack-year history of cigarette smoking. Physical ex... | Bronchial carcinoid | Adenocarcinoma of the lung | Small cell carcinoma of the lung | Lung abscess | 2c | multi | Hyponatremia in association with a lung mass usually indicates small cell lung cancer (SCLC) with inappropriate antidiuretic hormone (ADH) production by the tumor. About 10% of lung cancers present with a paraneoplastic syndrome. Tumors producing ADH or adrenocorticotropic hormone (ACTH) are overwhelmingly SCLCs, which... | Medicine | Respiratory | 158 | {
"Correct Answer": "Small cell carcinoma of the lung",
"Correct Option": "C",
"Options": {
"A": "Bronchial carcinoid",
"B": "Adenocarcinoma of the lung",
"C": "Small cell carcinoma of the lung",
"D": "Lung abscess"
},
"Question": "A 57-year-old man presents with hemoptysis and generalized wea... | A 57-year-old man presents with hemoptysis and generalized weakness. His symptoms began with small-volume hemoptysis 4 weeks ago. Over the past 2 weeks, he has become weak and feels "out of it." His appetite has diminished, and he has lost 10 lb of weight. He has a 45-pack-year history of cigarette smoking. Physical ex... | What is the most likely cause of his symptoms? | {
"A": "Bronchial carcinoid",
"B": "Adenocarcinoma of the lung",
"C": "Small cell carcinoma of the lung",
"D": "Lung abscess"
} | C. Small cell carcinoma of the lung |
0c5ee077-1330-4d61-9ab9-d9a3b46ac389 | A 23-year-old, sexually active man has been treated for Neisseria gonorrhoeae infection 6 times during the past 5 years. He now comes to the physician because of the increasing number and size of warty lesions slowly enlarging on his external genitalia during the past year. On physical examination, there are multiple 1... | Candida albicans infection | Circumcision | Human papillomavirus infection | Neisseria gonorrhoeae infection | 2c | multi | Condyloma acuminatum is a benign, recurrent squamous epithelial proliferation resulting from infection with human papillomavirus (HPV) infection, one of many sexually transmitted diseases that can occur in sexually active individuals. Koilocytosis is particularly characteristic of HPV infection. Candidiasis can be asso... | Pathology | Male Genital Tract | 137 | {
"Correct Answer": "Human papillomavirus infection",
"Correct Option": "C",
"Options": {
"A": "Candida albicans infection",
"B": "Circumcision",
"C": "Human papillomavirus infection",
"D": "Neisseria gonorrhoeae infection"
},
"Question": "A 23-year-old, sexually active man has been treated fo... | A 23-year-old, sexually active man has been treated for Neisseria gonorrhoeae infection 6 times during the past 5 years. He now comes to the physician because of the increasing number and size of warty lesions slowly enlarging on his external genitalia during the past year. On physical examination, there are multiple 1... | Which of the following conditions most likely predisposed him to the development of these recurrent lesions? | {
"A": "Candida albicans infection",
"B": "Circumcision",
"C": "Human papillomavirus infection",
"D": "Neisseria gonorrhoeae infection"
} | C. Human papillomavirus infection |
d387c2b9-3e1c-4d75-9155-9424475cb31d | A 23-year-old woman has noticed that she develops a skin rash if she spends prolonged periods outdoors. She has a malar skin rash on physical examination. Laboratory studies include a positive ANA test result with a titer of 1 :1024 and a "rim" pattern. An anti-double-stranded DNA test result also is positive. The hemo... | Basophilia | Eosinophilia | Monocytosis | Neutrophilia | 2c | single | An autoimmune disease, most likely systemic lupus erythematosus (SLE) in this patient, can be accompanied by monocytosis. Cytopenias also can occur in SLE because of autoantibodies against blood elements, a form of type II hypersensitivity. Basophilia occurs infrequently, but also can be seen in chronic myelogenous leu... | Pathology | Blood | 153 | {
"Correct Answer": "Monocytosis",
"Correct Option": "C",
"Options": {
"A": "Basophilia",
"B": "Eosinophilia",
"C": "Monocytosis",
"D": "Neutrophilia"
},
"Question": "A 23-year-old woman has noticed that she develops a skin rash if she spends prolonged periods outdoors. She has a malar skin ra... | A 23-year-old woman has noticed that she develops a skin rash if she spends prolonged periods outdoors. She has a malar skin rash on physical examination. Laboratory studies include a positive ANA test result with a titer of 1 :1024 and a "rim" pattern. An anti-double-stranded DNA test result also is positive. The hemo... | Which of the following findings is most likely to be shown by a WBC differential count? | {
"A": "Basophilia",
"B": "Eosinophilia",
"C": "Monocytosis",
"D": "Neutrophilia"
} | C. Monocytosis |
f03b37d6-8334-4a73-9007-56327bb663fd | A neonate within 4 hours of bih presented with severe respiratory distress. He appears to be dyspneic, tachypneic, and cyanotic with severe retractions of the chest. On examination, grunting is present along with use of the accessory muscles. Neonate also appears to have scaphoid abdomen and increased chest wall diamet... | PA C | PA A | PA D | PA B | 2c | multi | This is a case of congenital diaphragmatic hernia (bochdalek or posterolateral hernia) Chest radiograph shows a stomach, nasogastric tube, and small bowel contents in the thoracic cavity, consistent with a CDH. Development of Diaphragm: PA A: Body wall: Peripheral muscular pa PA B: Oesophageal Mesentery: Crura PA C: Se... | Unknown | Integrated QBank | 121 | {
"Correct Answer": "PA D",
"Correct Option": "C",
"Options": {
"A": "PA C",
"B": "PA A",
"C": "PA D",
"D": "PA B"
},
"Question": "A neonate within 4 hours of bih presented with severe respiratory distress. He appears to be dyspneic, tachypneic, and cyanotic with severe retractions of the ches... | A neonate within 4 hours of bih presented with severe respiratory distress. He appears to be dyspneic, tachypneic, and cyanotic with severe retractions of the chest. On examination, grunting is present along with use of the accessory muscles. Neonate also appears to have scaphoid abdomen and increased chest wall diamet... | Chest x ray of the neonate Defect in development of which pa of the responsible structure is causing this condition of the baby? | {
"A": "PA C",
"B": "PA A",
"C": "PA D",
"D": "PA B"
} | C. PA D |
810f38cb-3f85-42be-a9ba-71610e4fd911 | Apgar scores were 3, and 6 at 1 and 5 minutes. At 10 Apgar scores were 3, and 6 at 1 and 5 minutes. At 10 minutes child shows features of breathlessness,on CXR-mediastinal shift was there, possible causes –
a) Bilateral choanal atresiab) Pneumothoraxc) Congenital diaphragmatic herniad) Hyaline membrane disease | a | bc | ac | ad | 1b | single | Congenital diaphragmatic hernia and pneumothorax cause respiratory distress with mediastinal shift to contralateral side.
Bilateral choanal atresia and HMD cause respiratory distress, but no mediastinal shift. | Radiology | null | 102 | {
"Correct Answer": "bc",
"Correct Option": "B",
"Options": {
"A": "a",
"B": "bc",
"C": "ac",
"D": "ad"
},
"Question": "Apgar scores were 3, and 6 at 1 and 5 minutes. At 10 Apgar scores were 3, and 6 at 1 and 5 minutes. At 10 minutes child shows features of breathlessness,on CXR-mediastinal sh... | Apgar scores were 3, and 6 at 1 and 5 minutes. At 10 Apgar scores were 3, and 6 at 1 and 5 minutes. | At 10 minutes child shows features of breathlessness,on CXR-mediastinal shift was there, possible causes –
a) Bilateral choanal atresiab) Pneumothoraxc) Congenital diaphragmatic herniad) Hyaline membrane disease | {
"A": "a",
"B": "bc",
"C": "ac",
"D": "ad"
} | B. bc |
c4d050b6-9c49-4370-9e33-cf93a6c99b95 | An epidemiologic study observes increased numbers of respiratory tract infections among children living in a community in which most families are at the poverty level. The infectious agents include Streptococcus pneumoniae, Haemophilus influenzae, and Klebsiella pneumoniae. Most of the children have had pneumonitis and... | Vitamin A | Vitamin B1 | Vitamin E | Vitamin D | 0a | single | Vitamin A is important in maintaining epithelial surfaces. Deficiency of this vitamin can lead to squamous metaplasia of respiratory epithelium, predisposing to infection. Increased keratin buildup leads to follicular plugging and papular dermatosis. Desquamated keratinaceous debris in the urinary tract forms the nidus... | Pathology | Environment & Nutritional Pathology | 115 | {
"Correct Answer": "Vitamin A",
"Correct Option": "A",
"Options": {
"A": "Vitamin A",
"B": "Vitamin B1",
"C": "Vitamin E",
"D": "Vitamin D"
},
"Question": "An epidemiologic study observes increased numbers of respiratory tract infections among children living in a community in which most fami... | An epidemiologic study observes increased numbers of respiratory tract infections among children living in a community in which most families are at the poverty level. The infectious agents include Streptococcus pneumoniae, Haemophilus influenzae, and Klebsiella pneumoniae. Most of the children have had pneumonitis and... | These children are most likely to have a deficiency of which of the following vitamins? | {
"A": "Vitamin A",
"B": "Vitamin B1",
"C": "Vitamin E",
"D": "Vitamin D"
} | A. Vitamin A |
44efcde8-dadc-4ad5-9072-142f27d84768 | A 30-year-old man has had cramping abdominal pain and bloody diarrhea for the past 4 days. On physical examination, there is diffuse tenderness on palpation of the abdomen. Bowel sounds are present. There are no masses and no organomegaly. A stool culture is positive for Shigella flexneri. The episode resolves spontane... | Borrelia burgdorferi | Chlamydia trachomatis | Epstein-Barr virus | HLA-B27 | 3d | single | This patient developed enteritis-associated arthritis affecting the lumbar and sacroiliac joints several weeks after Shigella dysentery. He subsequently developed conjunctivitis and, most likely, uveitis. This symptom complex is a classic representation of a cluster of related disorders called seronegative spondyloarth... | Pathology | Osteology | 166 | {
"Correct Answer": "HLA-B27",
"Correct Option": "D",
"Options": {
"A": "Borrelia burgdorferi",
"B": "Chlamydia trachomatis",
"C": "Epstein-Barr virus",
"D": "HLA-B27"
},
"Question": "A 30-year-old man has had cramping abdominal pain and bloody diarrhea for the past 4 days. On physical examina... | A 30-year-old man has had cramping abdominal pain and bloody diarrhea for the past 4 days. On physical examination, there is diffuse tenderness on palpation of the abdomen. Bowel sounds are present. There are no masses and no organomegaly. A stool culture is positive for Shigella flexneri. The episode resolves spontane... | Serologic testing for which of the following is most likely to be positive in this patient? | {
"A": "Borrelia burgdorferi",
"B": "Chlamydia trachomatis",
"C": "Epstein-Barr virus",
"D": "HLA-B27"
} | D. HLA-B27 |
eacec070-a402-4eb3-845e-8452e0ee972d | A 40-year-old man without a significant medical history comes to the emergency room with a 3-day history of fever and shaking chills, and a 15-minute episode of rigor. He also reports a cough productive of yellow-green sputum, anorexia, and the development of right-sided pleuritic chest pain. Shortness of breath has be... | Recent exposure to a family member with influenza | Respiratory rate of 36/min | Recent sexual exposure to an HIV-positive patient | Purulent sputum with gram-positive diplococci on Gram stain | 1b | single | Because of the development of effective oral antibiotics (respiratory fluoroquinolones, extended spectrum macrolides), many patients with community-acquired pneumonia (CAP) can be managed as an outpatient as long as compliance and close follow-up are assured. The CURB-65 score is a validated instrument for determining ... | Medicine | Respiratory | 130 | {
"Correct Answer": "Respiratory rate of 36/min",
"Correct Option": "B",
"Options": {
"A": "Recent exposure to a family member with influenza",
"B": "Respiratory rate of 36/min",
"C": "Recent sexual exposure to an HIV-positive patient",
"D": "Purulent sputum with gram-positive diplococci on Gram s... | A 40-year-old man without a significant medical history comes to the emergency room with a 3-day history of fever and shaking chills, and a 15-minute episode of rigor. He also reports a cough productive of yellow-green sputum, anorexia, and the development of right-sided pleuritic chest pain. Shortness of breath has be... | Which feature would most strongly support inpatient admission and IV antibiotic treatment for this patient? | {
"A": "Recent exposure to a family member with influenza",
"B": "Respiratory rate of 36/min",
"C": "Recent sexual exposure to an HIV-positive patient",
"D": "Purulent sputum with gram-positive diplococci on Gram stain"
} | B. Respiratory rate of 36/min |
c3d09d72-c744-453d-b9a4-675f321fb655 | The 27-year-old male triathlon competitor complained that he frequently experienced deep pains in one calf that almost caused him to drop out of a regional track-and-field event. Doppler ultrasound studies indicated, and surgical exposure confirmed, the existence of an accessory portion of the medial head of the gastro... | Tendon of biceps femoris | Tendons of semitendinosus and semimembranosus | Tendon of plantaris | Tendinous hiatus of adductor magnus | 1b | multi | The tendons of the semitendinosus and semimembranosus provide the superior medial border of the popliteal fossa. The semitendinosus inserts with the pes anserinus on the proximal, medial tibia. The semimembranosus inserts on the tibia posteriorly. The biceps femoris forms the superior lateral border of the fossa, as th... | Anatomy | Lower Extremity | 109 | {
"Correct Answer": "Tendons of semitendinosus and semimembranosus",
"Correct Option": "B",
"Options": {
"A": "Tendon of biceps femoris",
"B": "Tendons of semitendinosus and semimembranosus",
"C": "Tendon of plantaris",
"D": "Tendinous hiatus of adductor magnus"
},
"Question": "The 27-year-old... | The 27-year-old male triathlon competitor complained that he frequently experienced deep pains in one calf that almost caused him to drop out of a regional track-and-field event. Doppler ultrasound studies indicated, and surgical exposure confirmed, the existence of an accessory portion of the medial head of the gastro... | Which of the following structures forms this border? | {
"A": "Tendon of biceps femoris",
"B": "Tendons of semitendinosus and semimembranosus",
"C": "Tendon of plantaris",
"D": "Tendinous hiatus of adductor magnus"
} | B. Tendons of semitendinosus and semimembranosus |
371ac31c-1a40-4504-9606-186ebb9e2820 | A 56 year old man has been having bloody bowel movements on and off for the past several weeks. He repos that the blood is bright red, it coats the outside of the stools, and he can see it in the toilet bowl even before he wipes himself. When he does so, there is also blood on the toilet paper. After fuher questioning,... | Anal fissure | Cancer of the cecum | Cancer of the rectum | External hemorrhoids | 2c | single | The combination of red blood coating the stools and a change in bowel habit and stool caliber spells out cancer of the rectum in someone in this age group. Anal fissure is typically seen in young women who have very painful bowel movements with streaks of blood. Pain is the dominant symptom in this condition. Cancer of... | Surgery | null | 137 | {
"Correct Answer": "Cancer of the rectum",
"Correct Option": "C",
"Options": {
"A": "Anal fissure",
"B": "Cancer of the cecum",
"C": "Cancer of the rectum",
"D": "External hemorrhoids"
},
"Question": "A 56 year old man has been having bloody bowel movements on and off for the past several wee... | A 56 year old man has been having bloody bowel movements on and off for the past several weeks. He repos that the blood is bright red, it coats the outside of the stools, and he can see it in the toilet bowl even before he wipes himself. When he does so, there is also blood on the toilet paper. After fuher questioning,... | Which of the following is the most likely diagnosis? | {
"A": "Anal fissure",
"B": "Cancer of the cecum",
"C": "Cancer of the rectum",
"D": "External hemorrhoids"
} | C. Cancer of the rectum |
87b19c10-d3b3-4357-af21-51019d1f77a8 | A 64-year-old man, who is a chronic alcoholic, presents with fever, chills and increasing shoness of breath. The patient appears in acute respiratory distress and complains of pleuritic chest pain. Physical examination shows crackles and decreased breath sounds over both lung fields. The patient exhibits tachypnea, wit... | Legionella pneumophila | Klebsiella pneumoniae | Mycoplasma pneumoniae | Streptococcus pneumoniae | 1b | multi | Klebsiella pneumoniae is the most frequent cause of gram-negative bacterial pneumonia. It commonly afflicts debilitated and malnourished people, paicularly chronic alcoholics. Thick, mucoid (often blood-tinged) sputum is characteristic because the organism produces an abundant viscid capsular polysac-charide, which the... | Pathology | Infectious Lung Disease: Pneumonia | 108 | {
"Correct Answer": "Klebsiella pneumoniae",
"Correct Option": "B",
"Options": {
"A": "Legionella pneumophila",
"B": "Klebsiella pneumoniae",
"C": "Mycoplasma pneumoniae",
"D": "Streptococcus pneumoniae"
},
"Question": "A 64-year-old man, who is a chronic alcoholic, presents with fever, chills... | A 64-year-old man, who is a chronic alcoholic, presents with fever, chills and increasing shoness of breath. The patient appears in acute respiratory distress and complains of pleuritic chest pain. Physical examination shows crackles and decreased breath sounds over both lung fields. The patient exhibits tachypnea, wit... | Which of the following pathogens is the most common cause of this patient's pulmonary infection? | {
"A": "Legionella pneumophila",
"B": "Klebsiella pneumoniae",
"C": "Mycoplasma pneumoniae",
"D": "Streptococcus pneumoniae"
} | B. Klebsiella pneumoniae |
3d38919b-c151-4f05-97e2-8bb90e4ee93d | A 29-year-old woman on oral contraceptives presents with abdominal pain. A computed tomography (CT) scan of the abdomen demonstrates a large hematoma of the right liver with the suggestion of an underlying liver lesion. Her hemoglobin is 6, and she is transfused 2 units of packed red blood cells and 2 units of fresh fr... | Continue the transfusion and administer an antihistamine | Stop the transfusion and administer a diuretic | Stop the transfusion, perform bronchoscopy, and sta broad-spectrum empiric antibiotics | Stop the transfusion and continue suppoive respiratory care | 3d | multi | The patient has TRALI or transfusion-related acute lung injury which manifests as respiratory distress, hypoxemia, and bilateral pulmonary infiltrates not due to volume overload. The treatment of choice is respiratory suppo, including mechanical ventilation, as needed. The major risk factor for TRALI is transfusion of ... | Anaesthesia | Miscellaneous | 124 | {
"Correct Answer": "Stop the transfusion and continue suppoive respiratory care",
"Correct Option": "D",
"Options": {
"A": "Continue the transfusion and administer an antihistamine",
"B": "Stop the transfusion and administer a diuretic",
"C": "Stop the transfusion, perform bronchoscopy, and sta broad... | A 29-year-old woman on oral contraceptives presents with abdominal pain. A computed tomography (CT) scan of the abdomen demonstrates a large hematoma of the right liver with the suggestion of an underlying liver lesion. Her hemoglobin is 6, and she is transfused 2 units of packed red blood cells and 2 units of fresh fr... | Which of the following is the management strategy of choice? | {
"A": "Continue the transfusion and administer an antihistamine",
"B": "Stop the transfusion and administer a diuretic",
"C": "Stop the transfusion, perform bronchoscopy, and sta broad-spectrum empiric antibiotics",
"D": "Stop the transfusion and continue suppoive respiratory care"
} | D. Stop the transfusion and continue suppoive respiratory care |
5585da3c-5132-4b3d-89f5-cd27c8172713 | A 67-year-old man with an 18-year history of type 2 diabetes mellitus presents for a routine physical examination. His temperature is 36.9 C (98.5 F), his blood pressure is 158/98 mm Hg and his pulse is 82/minute and regular. On examination, the physician notes a non tender, pulsatile, mass in the mid-abdomen. A plain ... | Atorvastatin | Cholestyramine | Clofibrate | Gemfibrozil | 1b | single | Cholestyramine and colestipol are bile acid sequestrants that bind bile acids in the intestine, thereby interrupting enterohepatic circulation of bile acids. This has an indirect effect to enhance LDL clearance and lower lipids in the blood. Atorvastatin and lovastatin are lipid-lowering drugs that competitively inhibi... | Pharmacology | null | 180 | {
"Correct Answer": "Cholestyramine",
"Correct Option": "B",
"Options": {
"A": "Atorvastatin",
"B": "Cholestyramine",
"C": "Clofibrate",
"D": "Gemfibrozil"
},
"Question": "A 67-year-old man with an 18-year history of type 2 diabetes mellitus presents for a routine physical examination. His tem... | A 67-year-old man with an 18-year history of type 2 diabetes mellitus presents for a routine physical examination. His temperature is 36.9 C (98.5 F), his blood pressure is 158/98 mm Hg and his pulse is 82/minute and regular. On examination, the physician notes a non tender, pulsatile, mass in the mid-abdomen. A plain ... | Which of the following agents was MOST likely prescribed? | {
"A": "Atorvastatin",
"B": "Cholestyramine",
"C": "Clofibrate",
"D": "Gemfibrozil"
} | B. Cholestyramine |
3a6b4569-defb-49b4-8430-ff9ea210a929 | A 69 year old male presents with an episode of slurring of speech which lasted for 12 hours and then resolved.He is heavy smoker having smoked 60 cigarettes per day for 40 years. He had a single episode of haemoptysis 4 weeks previously and has underlying lung cancer with brain metastases and is referred for an urgent ... | Left atrial myxoma | Left atrial thrombus | Infective endocarditis | Rhabdomyoma | 1b | multi | The axial image from a contrast enhanced CT scan, in aerial phase, shows a filling defect in the left atrial appendage layered along the anterior wall. Given the clinical history and the CT appearance, the most likely diagnosis is of thrombus in the LA as a consequence of AF. Myxomas generally arise from interatrial se... | Radiology | Cardiovascular Radiology | 111 | {
"Correct Answer": "Left atrial thrombus",
"Correct Option": "B",
"Options": {
"A": "Left atrial myxoma",
"B": "Left atrial thrombus",
"C": "Infective endocarditis",
"D": "Rhabdomyoma"
},
"Question": "A 69 year old male presents with an episode of slurring of speech which lasted for 12 hours ... | A 69 year old male presents with an episode of slurring of speech which lasted for 12 hours and then resolved.He is heavy smoker having smoked 60 cigarettes per day for 40 years. He had a single episode of haemoptysis 4 weeks previously and has underlying lung cancer with brain metastases and is referred for an urgent ... | Which of the following is most probable diagnosis? | {
"A": "Left atrial myxoma",
"B": "Left atrial thrombus",
"C": "Infective endocarditis",
"D": "Rhabdomyoma"
} | B. Left atrial thrombus |
d2c083fb-c7d7-40a9-8802-59bf29188590 | A 30 year old G1P1001 patient comes to see you In office at 37 weeks gestational age for her routine OB visit. Her 1st pregnancy resulted in a vaginal delivery of a 9-lb, 8-02 baby boy after 30 minutes of pushing. On doing Leopold maneuvers during this office visit codetermine ttwt the fetus is breech. Vaginal exam dem... | Allow the patient to undergo a vaginal breech delivery whenever she goes into labor | Send the patient to labor and delivery immediately for an emergen CS | Schedule a CS at or after 39 weeks gestation a | Schedule an ext cephalic version In next few days | 1b | multi | definite indications for elective Caesarean section all complicated breech pregnancy Contracted or borderline pelvis Large babies Severe IUGR Hyper extension of fetal head Footling or knee presentation Previous Caesarean section Lack of an obstetrician experienced in assisted breech delivery can also be considered an i... | Gynaecology & Obstetrics | Abnormal labor | 192 | {
"Correct Answer": "Send the patient to labor and delivery immediately for an emergen CS",
"Correct Option": "B",
"Options": {
"A": "Allow the patient to undergo a vaginal breech delivery whenever she goes into labor",
"B": "Send the patient to labor and delivery immediately for an emergen CS",
"C": ... | A 30 year old G1P1001 patient comes to see you In office at 37 weeks gestational age for her routine OB visit. Her 1st pregnancy resulted in a vaginal delivery of a 9-lb, 8-02 baby boy after 30 minutes of pushing. On doing Leopold maneuvers during this office visit codetermine ttwt the fetus is breech. Vaginal exam dem... | There is a normal am &; amniotic fluid present, and the head is well-felt the patient&;s obstetrician, you offer all the following possible mgmt plans except | {
"A": "Allow the patient to undergo a vaginal breech delivery whenever she goes into labor",
"B": "Send the patient to labor and delivery immediately for an emergen CS",
"C": "Schedule a CS at or after 39 weeks gestation a",
"D": "Schedule an ext cephalic version In next few days"
} | B. Send the patient to labor and delivery immediately for an emergen CS |
b6f6520e-b4a8-4acd-9621-bda51a06f76f | A study was conducted to test if use of herbal tea played any role in prevention of common cold. Data was collected on the number of people who developed cold and those who did not develop cold and this data was tabulated in relation to whether they consumed Herbal tea or not.\r\n\r\n\r\n\r\n Herbal tea \r\nConsumed\r\... | 'Z' test | Chi square test | Student -1 test (paired) | Student -1 test (unpaired) | 1b | multi | According to the question, the data that has to assessed is the nominal data which has been arranged in qualified categories and thus by using a non-parametric test, the Chi square test is used for the analytical study of the test. The student t-test (unpaired and paired t test) and the 'z' test are parametric tests th... | Social & Preventive Medicine | null | 141 | {
"Correct Answer": "Chi square test",
"Correct Option": "B",
"Options": {
"A": "'Z' test",
"B": "Chi square test",
"C": "Student -1 test (paired)",
"D": "Student -1 test (unpaired)"
},
"Question": "A study was conducted to test if use of herbal tea played any role in prevention of common cold... | A study was conducted to test if use of herbal tea played any role in prevention of common cold. | Data was collected on the number of people who developed cold and those who did not develop cold and this data was tabulated in relation to whether they consumed Herbal tea or not.\r\n\r\n\r\n\r\n Herbal tea \r\nConsumed\r\nNot consumed\r\n\r\n\r\n Had cold \r\n12\r\n 23\r\n\r\n\r\n Did not have a cold \r\n 34\r\n38\r\... | {
"A": "'Z' test",
"B": "Chi square test",
"C": "Student -1 test (paired)",
"D": "Student -1 test (unpaired)"
} | B. Chi square test |
cd6ef7dd-345d-44f7-8c57-193e747f7bb1 | An epidemiologic study evaluates the rate of dental caries and tooth abscesses among children living in communities within a metropolitan area. Investigators discover that the rate is high among children living in an upper-middle-class community but low in children living in a community below the poverty level. The lev... | Copper | Fluoride | Iodine | Selenium | 1b | single | Water in some areas naturally contains fluoride, and dental problems in children are fewer in these areas because tooth enamel is strengthened. Fluoride can be added to drinking water, but opposition to this practice, from ignorance or fear, is common. Copper deficiency can produce neurologic defects. Iodine deficiency... | Pathology | Environment & Nutritional Pathology | 105 | {
"Correct Answer": "Fluoride",
"Correct Option": "B",
"Options": {
"A": "Copper",
"B": "Fluoride",
"C": "Iodine",
"D": "Selenium"
},
"Question": "An epidemiologic study evaluates the rate of dental caries and tooth abscesses among children living in communities within a metropolitan area. Inv... | An epidemiologic study evaluates the rate of dental caries and tooth abscesses among children living in communities within a metropolitan area. Investigators discover that the rate is high among children living in an upper-middle-class community but low in children living in a community below the poverty level. The lev... | A higher level of which of the following minerals in the water is most likely to be associated with a lower rate of dental decay among the children living in the poor community? | {
"A": "Copper",
"B": "Fluoride",
"C": "Iodine",
"D": "Selenium"
} | B. Fluoride |
8add0ee7-5f96-4f91-ba5f-fc34ca99d3cd | A 65 year old white male in previously good health sta to notice blood in his urine. He develops pain with urination. He also thinks that the stream of his urine is weakened. He goes to his family doctor because of his symptoms. Laboratory findings show an anemia. His urinalysis is positive for red cells, white cells a... | It is likely to be an adenocarcinoma | More commonly presents with a palpable abdominal mass | Likely to cause an elevated serum acid phosphatase | Is likely to recur after treatment | 3d | multi | Is likely to recur after treatment * Even after treatment, transitional cell cancers of the bladder tend to recur. * Choice (a) is incorrect because about 90% of bladder cancers are transitional cell carcinomas. * The classic triad: hematuria, flank pain, and a palpable abdominal mass is associated with renal cell carc... | Surgery | null | 114 | {
"Correct Answer": "Is likely to recur after treatment",
"Correct Option": "D",
"Options": {
"A": "It is likely to be an adenocarcinoma",
"B": "More commonly presents with a palpable abdominal mass",
"C": "Likely to cause an elevated serum acid phosphatase",
"D": "Is likely to recur after treatme... | A 65 year old white male in previously good health sta to notice blood in his urine. He develops pain with urination. He also thinks that the stream of his urine is weakened. He goes to his family doctor because of his symptoms. Laboratory findings show an anemia. His urinalysis is positive for red cells, white cells a... | Which of the following is true of this patient's tumor? | {
"A": "It is likely to be an adenocarcinoma",
"B": "More commonly presents with a palpable abdominal mass",
"C": "Likely to cause an elevated serum acid phosphatase",
"D": "Is likely to recur after treatment"
} | D. Is likely to recur after treatment |
b50294a0-bf80-4042-9ed9-87a6ef5e2e10 | A 49-year-old woman has experienced increasing weakness and chest pain over the past 6 months. On physical examination, she is afebrile and normotensive. Motor strength is 5/5 in all extremities, but diminishes to 4/5 with repetitive movement. There is no muscle pain or tenderness. Laboratory studies show hemoglobin, 1... | Extrapulmonary tuberculosis | Hodgkin lymphoma | Lymphoblastic lymphoma | Malignant thymoma | 3d | multi | Thymomas are rare neoplasms that can be benign or malignant. In one third to one half of cases, thymomas are associated with myasthenia gravis as an initial presentation (as in this case). Benign thymomas have a mixed population of lymphocytes and epithelial cells and are circumscribed, whereas malignant thymomas are i... | Pathology | Blood | 194 | {
"Correct Answer": "Malignant thymoma",
"Correct Option": "D",
"Options": {
"A": "Extrapulmonary tuberculosis",
"B": "Hodgkin lymphoma",
"C": "Lymphoblastic lymphoma",
"D": "Malignant thymoma"
},
"Question": "A 49-year-old woman has experienced increasing weakness and chest pain over the past... | A 49-year-old woman has experienced increasing weakness and chest pain over the past 6 months. On physical examination, she is afebrile and normotensive. Motor strength is 5/5 in all extremities, but diminishes to 4/5 with repetitive movement. There is no muscle pain or tenderness. Laboratory studies show hemoglobin, 1... | Which of the following is the most likely cause of this mass lesion? | {
"A": "Extrapulmonary tuberculosis",
"B": "Hodgkin lymphoma",
"C": "Lymphoblastic lymphoma",
"D": "Malignant thymoma"
} | D. Malignant thymoma |
c07322bc-4b43-4c1a-839e-154aefcc3aa5 | A 25-year-old woman rushes to an emergency depament because she is afraid she is dying. She is experiencing chest pain, a sensation of choking, nausea, and tingling sensations up and down her arms. When the screening nurse examines the patient, her face is flushed and sweating. Her pulse is 140/min and respirations are... | Angina | Heaburn | Myocardial infarction | Panic attack | 3d | multi | This woman had a panic attack. These are common, affecting more than one third of the general population each year. The etiology appears to be a combination of both biological and psychological dysfunction. The sensations and physiologic changes can be very dramatic and, in addition to the features cited in the questio... | Psychiatry | null | 141 | {
"Correct Answer": "Panic attack",
"Correct Option": "D",
"Options": {
"A": "Angina",
"B": "Heaburn",
"C": "Myocardial infarction",
"D": "Panic attack"
},
"Question": "A 25-year-old woman rushes to an emergency depament because she is afraid she is dying. She is experiencing chest pain, a sen... | A 25-year-old woman rushes to an emergency depament because she is afraid she is dying. She is experiencing chest pain, a sensation of choking, nausea, and tingling sensations up and down her arms. When the screening nurse examines the patient, her face is flushed and sweating. Her pulse is 140/min and respirations are... | Which of the following is the most likely diagnosis? | {
"A": "Angina",
"B": "Heaburn",
"C": "Myocardial infarction",
"D": "Panic attack"
} | D. Panic attack |
234c6833-b1e3-4452-88bf-cfd490dc5bad | A 69-year-old man comes to the physician because of the gradual onset of pain, tingling and hyperesthesia in the medial aspect of his right arm. Shortly thereafter, he develops erythema and then an outbreak of vesicles on the medial aspect of his right arm extending from his medial epicondyle to the wrist. After severa... | Brainstem | Dorsal root ganglion | Sensory nerve axon | Sensory nerve root | 1b | multi | null | Medicine | null | 153 | {
"Correct Answer": "Dorsal root ganglion",
"Correct Option": "B",
"Options": {
"A": "Brainstem",
"B": "Dorsal root ganglion",
"C": "Sensory nerve axon",
"D": "Sensory nerve root"
},
"Question": "A 69-year-old man comes to the physician because of the gradual onset of pain, tingling and hypere... | A 69-year-old man comes to the physician because of the gradual onset of pain, tingling and hyperesthesia in the medial aspect of his right arm. Shortly thereafter, he develops erythema and then an outbreak of vesicles on the medial aspect of his right arm extending from his medial epicondyle to the wrist. After severa... | The infectious agent responsible for this condition resides in which part of the neuraxis? | {
"A": "Brainstem",
"B": "Dorsal root ganglion",
"C": "Sensory nerve axon",
"D": "Sensory nerve root"
} | B. Dorsal root ganglion |
153eb6d2-2430-4054-8c7a-5c0f3da4c493 | A 45 year old male presented with palpitations, tachycardia & anxiety. His BP is 158/90 mmHg. The patient also has mild depression and is presently taking citalopram, labetalol & amlodipine to control his blood pressure. 24-hour urine total metanephrines are ordered and show an elevation of 1.5 times the upper limit of... | Hold labetalol for 1 week and repeat testing | Hold citalopram for 1 week and repeat testing | Refer immediately for surgical evaluation | Measure 24-hour urine vanillylmandelic acid level | 0a | multi | Investigations done in pheochromocytoma 24 hour urinary fractionated metanephrine 24 hour urinary catecholamines 24 hour urinary vanillylmandelic acid level IOC- Plasma fractionated metanephrine levels 24-hour urine total metanephrines has high sensitivity & value of three times the upper limit of normal is highly sugg... | Medicine | Disorders of Adrenal Gland | 101 | {
"Correct Answer": "Hold labetalol for 1 week and repeat testing",
"Correct Option": "A",
"Options": {
"A": "Hold labetalol for 1 week and repeat testing",
"B": "Hold citalopram for 1 week and repeat testing",
"C": "Refer immediately for surgical evaluation",
"D": "Measure 24-hour urine vanillylm... | A 45 year old male presented with palpitations, tachycardia & anxiety. His BP is 158/90 mmHg. The patient also has mild depression and is presently taking citalopram, labetalol & amlodipine to control his blood pressure. 24-hour urine total metanephrines are ordered and show an elevation of 1.5 times the upper limit of... | What is the next best step? | {
"A": "Hold labetalol for 1 week and repeat testing",
"B": "Hold citalopram for 1 week and repeat testing",
"C": "Refer immediately for surgical evaluation",
"D": "Measure 24-hour urine vanillylmandelic acid level"
} | A. Hold labetalol for 1 week and repeat testing |
5bedaef6-8d34-446e-b094-f42fca1dbd12 | A pharmaceutical company develops a new antihypertensive drug. Samples of 24 hypertensive patients, randomly selected from a large population of hypertensive people, are randomly divided into 2 groups of 12. One group is given the new drug over a period of 1 month; the other group is given a placebo according to the sa... | Is a randomized controlled clinical trial | Uses a crossover design | Is a single blind experiment | Is a prospective study | 0a | single | Here, a pharmaceutical company develops a new anti-hypertensive drug; samples of 24 hypertensive patients, randomly selected from a large population of hypertensive people, are randomly divided into 2 groups of 12, and one group is given the new drug over a period of 1 month & the other group is given a placebo accordi... | Social & Preventive Medicine | null | 110 | {
"Correct Answer": "Is a randomized controlled clinical trial",
"Correct Option": "A",
"Options": {
"A": "Is a randomized controlled clinical trial",
"B": "Uses a crossover design",
"C": "Is a single blind experiment",
"D": "Is a prospective study"
},
"Question": "A pharmaceutical company dev... | A pharmaceutical company develops a new antihypertensive drug. Samples of 24 hypertensive patients, randomly selected from a large population of hypertensive people, are randomly divided into 2 groups of 12. One group is given the new drug over a period of 1 month; the other group is given a placebo according to the sa... | This study | {
"A": "Is a randomized controlled clinical trial",
"B": "Uses a crossover design",
"C": "Is a single blind experiment",
"D": "Is a prospective study"
} | A. Is a randomized controlled clinical trial |
d9e3512a-cb34-460b-8045-60083ae8387c | A 30 year old person met with a roadside accident. On admision his pulse rate was 120/minute, BP was 100/60 mmHg. Ultrasonagraphy examination revealed laceration of the lower pole of spleen and haemoperitoneum. He was resuscitated with blood and fluid. Two hours later, his pulse was 84/minute and BP was 120/70 mm Hg. T... | Exploring the patient followed by splenectomy | Exploring the patient followed by excision of the lower pole of spleen | Splenorrhaphy | Continuation of conservative treatment under close monitoring system and subsequent surgery if further indicated | 3d | single | null | Surgery | null | 112 | {
"Correct Answer": "Continuation of conservative treatment under close monitoring system and subsequent surgery if further indicated",
"Correct Option": "D",
"Options": {
"A": "Exploring the patient followed by splenectomy",
"B": "Exploring the patient followed by excision of the lower pole of spleen",
... | A 30 year old person met with a roadside accident. On admision his pulse rate was 120/minute, BP was 100/60 mmHg. Ultrasonagraphy examination revealed laceration of the lower pole of spleen and haemoperitoneum. He was resuscitated with blood and fluid. Two hours later, his pulse was 84/minute and BP was 120/70 mm Hg. | The most appropriate course of management in this case would be- | {
"A": "Exploring the patient followed by splenectomy",
"B": "Exploring the patient followed by excision of the lower pole of spleen",
"C": "Splenorrhaphy",
"D": "Continuation of conservative treatment under close monitoring system and subsequent surgery if further indicated"
} | D. Continuation of conservative treatment under close monitoring system and subsequent surgery if further indicated |
24e6e46a-91bb-4c8d-9047-170fe6250e05 | Several weeks after surgical dissection of her left axilla for the removal of lymph nodes for staging and treatment of her breast cancer, a 32-year-old woman was told by her general physician that she had "winging" of her left scapula when she pushed against resistance during her physical examination. She told the phys... | The upper trunk of her brachial plexus | The posterior division of the middle trunk | Roots of the brachial plexus | The posterior cord of the brachial plexus | 2c | multi | The long thoracic nerve was injured during the axillary dissection, resulting in paralysis of the serratus anterior. The serratus anterior is important in rotation of the scapula in raising the arm above the level of the shoulder. Its loss results in protrusion of the inferior angle ("winging" of the scapula), which is... | Anatomy | Upper Extremity | 139 | {
"Correct Answer": "Roots of the brachial plexus",
"Correct Option": "C",
"Options": {
"A": "The upper trunk of her brachial plexus",
"B": "The posterior division of the middle trunk",
"C": "Roots of the brachial plexus",
"D": "The posterior cord of the brachial plexus"
},
"Question": "Severa... | Several weeks after surgical dissection of her left axilla for the removal of lymph nodes for staging and treatment of her breast cancer, a 32-year-old woman was told by her general physician that she had "winging" of her left scapula when she pushed against resistance during her physical examination. She told the phys... | What was the origin of this nerve? | {
"A": "The upper trunk of her brachial plexus",
"B": "The posterior division of the middle trunk",
"C": "Roots of the brachial plexus",
"D": "The posterior cord of the brachial plexus"
} | C. Roots of the brachial plexus |
f0db5ac0-ee6e-413f-82ab-0ccbff11eab1 | A 19-year-old man is brought to the emergency department with a stab wound at the base of the neck (zone I) (Figure below). The most important concern for patients with such injuries is which of the following?For the purpose of evaluating penetrating injuries, the neck is divided into three zones. Zone I is below the c... | Upper extremity ischemia | Cerebral infarction | Exsanguinating hemorrhage | Mediastinitis | 2c | multi | Exsanguinating hemorrhage is the predominant risk, because bleeding may not be easily recognized, given that bleeding into the pleural cavity and mediastinum can occur. The abundant collateral blood supply generally protects against upper extremities or cerebrovascular compromise. | Surgery | Trauma | 104 | {
"Correct Answer": "Exsanguinating hemorrhage",
"Correct Option": "C",
"Options": {
"A": "Upper extremity ischemia",
"B": "Cerebral infarction",
"C": "Exsanguinating hemorrhage",
"D": "Mediastinitis"
},
"Question": "A 19-year-old man is brought to the emergency department with a stab wound at... | A 19-year-old man is brought to the emergency department with a stab wound at the base of the neck (zone I) (Figure below). The most important concern for patients with such injuries is which of the following?For the purpose of evaluating penetrating injuries, the neck is divided into three zones. Zone I is below the c... | Zone II is located between the clavicles and hyoid bone, and Zone III is above the hyoid. | {
"A": "Upper extremity ischemia",
"B": "Cerebral infarction",
"C": "Exsanguinating hemorrhage",
"D": "Mediastinitis"
} | C. Exsanguinating hemorrhage |
11fa2143-7c6e-4564-921b-e42ce2eba143 | A 40-year-old male patient presented to the dermatology OPD with complaints of a characteristic rash over the face along with fever, ahralgia and moderate chest pain. Patient gave history of using some drug for 3 months. On examination, there was no CNS involvement. Lab findings revealed normal urine r/m studies and no... | <img style="max-width: 100%" src=" /> | <img style="max-width: 100%" src=" /> | <img style="max-width: 100%" src=" /> | <img style="max-width: 100%" src=" /> | 3d | multi | This is a case of Drug induced Lupus. More common in females. Presents with the characteristic malar skin rash. Along with serositis, most commonly pleuritis. Kidney and CNS are rarely involved. Titres of anti-histone Abs are increased. It is a type 3 hypersensitivity reaction. It is associated with HLA-DR2 Image A sho... | Unknown | Integrated QBank | 103 | {
"Correct Answer": "<img style=\"max-width: 100%\" src=\" />",
"Correct Option": "D",
"Options": {
"A": "<img style=\"max-width: 100%\" src=\" />",
"B": "<img style=\"max-width: 100%\" src=\" />",
"C": "<img style=\"max-width: 100%\" src=\" />",
"D": "<img style=\"max-width: 100%\" src=\" />"
}... | A 40-year-old male patient presented to the dermatology OPD with complaints of a characteristic rash over the face along with fever, ahralgia and moderate chest pain. Patient gave history of using some drug for 3 months. On examination, there was no CNS involvement. Lab findings revealed normal urine r/m studies and no... | Which of the following mechanisms is most likely implicated in the above disease: - | {
"A": "<img style=\"max-width: 100%\" src=\" />",
"B": "<img style=\"max-width: 100%\" src=\" />",
"C": "<img style=\"max-width: 100%\" src=\" />",
"D": "<img style=\"max-width: 100%\" src=\" />"
} | D. <img style="max-width: 100%" src=" /> |
874e45c8-1b40-41c2-9fe5-3e9329a84653 | Many rashes and skin lesions can be found first in the newborn period. For each of the descriptions listed below, select the most likely diagnosis. Each lettered option may be used once, more than once, or not at all. An adolescent boy complains of a splotchy red rash on the nape of his neck, discovered when he had his... | Sebaceous nevus | Salmon patch | Neonatal acne | Pustular melanosis | 1b | multi | Salmon patches (aka nevus simplex or nevus flammeus) are flat vascular lesions that occur in the listed regions and appear more prominent during crying. The lesions on the face fade over the first few years of life. Lesions found over the nuchal and occipital areas often persist. No therapy is indicated. | Pediatrics | Growth, Development, and Behavior | 126 | {
"Correct Answer": "Salmon patch",
"Correct Option": "B",
"Options": {
"A": "Sebaceous nevus",
"B": "Salmon patch",
"C": "Neonatal acne",
"D": "Pustular melanosis"
},
"Question": "Many rashes and skin lesions can be found first in the newborn period. For each of the descriptions listed below,... | Many rashes and skin lesions can be found first in the newborn period. For each of the descriptions listed below, select the most likely diagnosis. Each lettered option may be used once, more than once, or not at all. An adolescent boy complains of a splotchy red rash on the nape of his neck, discovered when he had his... | He had a similar rash on his eyelids that resolved in the newborn period. | {
"A": "Sebaceous nevus",
"B": "Salmon patch",
"C": "Neonatal acne",
"D": "Pustular melanosis"
} | B. Salmon patch |
d12e78d3-6249-49de-8d70-680af7a2e738 | A 42-year old female presents with the complaint of bleeding gums for the past 20 days. Intra-oral examination shows thickened and friable gums. Also, she has hepatosplenomegaly with generalized non tender lymphadenopathy. The blood count reveals: Hemoglobin 11.4 g/dl, Platelet count 90,000/mm3, WBC count 4600/mm3. Th... | Acute lymphoblastic leukemia | Acute megakaryocytic leukemia | Acute promyelocytic leukemia | Acute monocytic leukemia | 3d | single | Patient has an “aleukemic” leukemia in which leukemic blasts fill the marrow, but the peripheral blood count of leukocytes is not high. The staining of the blasts suggests the presence of monoblasts (peroxidase negative and nonspecific esterase positive). So, the likely diagnosis for her is M5 leukemia, which is characte... | Pathology | null | 146 | {
"Correct Answer": "Acute monocytic leukemia",
"Correct Option": "D",
"Options": {
"A": "Acute lymphoblastic leukemia",
"B": "Acute megakaryocytic leukemia",
"C": "Acute promyelocytic leukemia",
"D": "Acute monocytic leukemia"
},
"Question": "A 42-year old female presents with the complaint o... | A 42-year old female presents with the complaint of bleeding gums for the past 20 days. Intra-oral examination shows thickened and friable gums. Also, she has hepatosplenomegaly with generalized non tender lymphadenopathy. The blood count reveals: Hemoglobin 11.4 g/dl, Platelet count 90,000/mm3, WBC count 4600/mm3. Th... | Which of the following is the most likely diagnosis for this patient? | {
"A": "Acute lymphoblastic leukemia",
"B": "Acute megakaryocytic leukemia",
"C": "Acute promyelocytic leukemia",
"D": "Acute monocytic leukemia"
} | D. Acute monocytic leukemia |
c43f4178-abb7-40c6-a1ab-dbb3cc44dd94 | An 18 years old male reported with chief complaint of sensitivity and deep, dull, radiating pain during chewing. Intra-oral examination showed sparase plague and dental calculus deposits, distolabial migration of the maxillary incisors with diastema formation, mobility of maxillary and mandibular incisors and first mol... | Subantimicrobial-dose clindamycin | Subantimicrobial-dose metronidazole | Subantimicrobial-dose doxycycline | Subantimicrobial-dose ciproftoxacin | 2c | single | null | Dental | null | 139 | {
"Correct Answer": "Subantimicrobial-dose doxycycline",
"Correct Option": "C",
"Options": {
"A": "Subantimicrobial-dose clindamycin",
"B": "Subantimicrobial-dose metronidazole",
"C": "Subantimicrobial-dose doxycycline",
"D": "Subantimicrobial-dose ciproftoxacin"
},
"Question": "An 18 years ol... | An 18 years old male reported with chief complaint of sensitivity and deep, dull, radiating pain during chewing. Intra-oral examination showed sparase plague and dental calculus deposits, distolabial migration of the maxillary incisors with diastema formation, mobility of maxillary and mandibular incisors and first mol... | There was vertical bone loss in the maxillary incisor region.
The host modulation therapy that may be used as adjunctive therapy for this disease is | {
"A": "Subantimicrobial-dose clindamycin",
"B": "Subantimicrobial-dose metronidazole",
"C": "Subantimicrobial-dose doxycycline",
"D": "Subantimicrobial-dose ciproftoxacin"
} | C. Subantimicrobial-dose doxycycline |
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