screen_file string | organism string | perturbation string | gene string | cell string | phenotype string | hit int64 | benchmark_type string | prompt string | gene_context string |
|---|---|---|---|---|---|---|---|---|---|
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Gart | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Gart in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Gart (phosphoribosylglycinamide formyltransferase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: 'de novo' AMP biosynthetic process, 'de novo' IMP biosynthetic process, 'de novo' XMP biosynthetic process, GMP biosynthetic process, adenine biosynthetic process, bra... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Bap1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Bap1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Bap1 (Brca1 associated protein 1)
Type: protein-coding
Summary: Enables chromatin DNA binding activity. Involved in several processes, including common myeloid progenitor cell proliferation; hematopoietic stem cell homeostasis; and myeloid cell differentiation. Acts upstream of or within macrophag... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Tkt | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Tkt in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Tkt (transketolase)
Type: protein-coding
Summary: This gene encodes an enzyme that binds magnesium and thiamine pyrophosphate and catalyzes the transfer of sugar phosphates to an aldose acceptor. This enzyme is a key component of the pentose phosphate pathway during glycolysis. It is significantly... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ppat | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ppat in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ppat (phosphoribosyl pyrophosphate amidotransferase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: 'de novo' AMP biosynthetic process, 'de novo' IMP biosynthetic process, 'de novo' XMP biosynthetic process, GMP biosynthetic process, L-glutamine catabolic process, ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mthfd1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mthfd1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mthfd1 (methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase)
Type: protein-coding
Summary: This gene encodes a trifunctional cytoplasmic enzyme. The encoded protein functions as a methylenetetrahydrofolate dehydrogenas... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl27a | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl27a in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl27a (ribosomal protein L27A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, translation, translation at postsynapse, translation at presynapse; MF: structural constituent of ribosome; CC: cytoplasm, cytosol, cytosolic large ribosomal sub... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Eif4a1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Eif4a1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Eif4a1 (eukaryotic translation initiation factor 4A1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translational initiation, positive regulation of transcription by RNA polymerase II, translation, translational initiation; MF: ATP binding, ATP hydroly... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl8 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl8 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl8 (ribosomal protein L8)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, translation, translation at postsynapse, translation at presynapse; MF: 5.8S rRNA binding, RNA binding, protein binding, rRNA binding, structural constituent of ribo... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Pfas | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Pfas in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Pfas (phosphoribosylformylglycinamidine synthase (FGAR amidotransferase))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: 'de novo' AMP biosynthetic process, 'de novo' IMP biosynthetic process, 'de novo' XMP biosynthetic process, GMP biosynthetic process, anterior h... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps3 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps3 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps3 (ribosomal protein S3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, apoptotic process, base-excision repair, cell division, cellular response to hydrogen peroxide, cellular response to reactive oxygen species, cellular respon... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps3a1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps3a1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps3a1 (ribosomal protein S3A1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell differentiation, cytoplasmic translation, negative regulation of apoptotic process, ribosomal small subunit biogenesis, translation; MF: mRNA 5'-UTR binding, mRNA binding, protein b... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpe | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpe in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpe (ribulose-5-phosphate-3-epimerase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: carbohydrate metabolic process, pentose-phosphate shunt, pentose-phosphate shunt, non-oxidative branch; MF: D-ribulose-phosphate 3-epimerase activity, carbohydrate binding, identi... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mocs3 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mocs3 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mocs3 (molybdenum cofactor synthesis 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Mo-molybdopterin cofactor biosynthetic process, molybdopterin cofactor biosynthetic process, protein urmylation, tRNA processing, tRNA thio-modification, tRNA wobble position uri... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Umps | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Umps in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Umps (uridine monophosphate synthetase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: 'de novo' UMP biosynthetic process, 'de novo' pyrimidine nucleobase biosynthetic process, UDP biosynthetic process, UMP biosynthetic process, pyrimidine nucleobase biosynthetic p... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Elp3 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Elp3 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Elp3 (elongator acetyltransferase complex subunit 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: central nervous system development, nervous system development, neuron migration, positive regulation of cell migration, regulation of transcription by RNA polymeras... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Sepsecs | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Sepsecs in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Sepsecs (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: conversion of seryl-tRNAsec to selenocys-tRNAsec, selenocysteine incorporation, translation; MF: O-phosphoseryl-tRNA(Sec) selenium transferase act... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Sin3a | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Sin3a in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Sin3a (transcriptional regulator, SIN3A (yeast))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA replication, activation of innate immune response, cellular response to dopamine, cellular response to glucose stimulus, cellular response to tert-butyl hydroperoxid... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl13 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl13 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl13 (ribosomal protein L13)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: blastocyst development, bone development, cytoplasmic translation, translation, translation at postsynapse, translation at presynapse; MF: RNA binding, structural constituent of ribosome; ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Chd4 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Chd4 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Chd4 (chromodomain helicase DNA binding protein 4)
Type: protein-coding
Summary: Enables DNA-binding transcription factor binding activity. Predicted to be involved in several processes, including double-strand break repair via homologous recombination; negative regulation of macromolecule biosynt... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Eif3d | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Eif3d in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Eif3d (eukaryotic translation initiation factor 3, subunit D)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: IRES-dependent viral translational initiation, cap-dependent translational initiation, cytoplasmic translational initiation, formation of cytoplasmic transl... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Eif3g | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Eif3g in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Eif3g (eukaryotic translation initiation factor 3, subunit G)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translational initiation, formation of cytoplasmic translation initiation complex, translation, translational initiation, viral translational te... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Exosc10 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Exosc10 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Exosc10 (exosome component 10)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: CUT catabolic process, DNA damage response, DNA repair, RNA catabolic process, RNA processing, TRAMP-dependent tRNA surveillance pathway, exonucleolytic trimming to generate mature 3'-end... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps27 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps27 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps27 (ribosomal protein S27)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: rRNA processing, ribosomal small subunit assembly, ribosomal small subunit biogenesis, translation, translation at postsynapse, translation at presynapse; MF: RNA binding, metal ion bindin... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Eif3i | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Eif3i in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Eif3i (eukaryotic translation initiation factor 3, subunit I)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translational initiation, formation of cytoplasmic translation initiation complex, translation, translational initiation; MF: RNA binding, prote... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Brd2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Brd2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Brd2 (bromodomain containing 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell surface receptor signaling pathway via JAK-STAT, chromatin looping, chromatin organization, chromatin remodeling, neural tube closure, nucleosome assembly, positive regulation of T-... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps5 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps5 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps5 (ribosomal protein S5)
Type: protein-coding
Summary: A structural constituent of ribosome. Predicted to be involved in regulation of translational fidelity; ribosomal small subunit assembly; and translation. Part of cytosolic small ribosomal subunit. Is active in synapse. Is expressed in seve... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Dph3 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Dph3 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Dph3 (diphthamine biosynthesis 3)
Type: protein-coding
Summary: Predicted to enable electron transfer activity; ferrous iron binding activity; and iron chaperone activity. Involved in protein histidyl modification to diphthamide. Part of protein-containing complex. Is active in cytosol. Orthologou... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl4 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl4 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl4 (ribosomal protein L4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, translation, translation at postsynapse, translation at presynapse; MF: 5S rRNA binding, RNA binding, protein binding, structural constituent of ribosome; CC: A band... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Elp5 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Elp5 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Elp5 (elongator acetyltransferase complex subunit 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: positive regulation of cell migration, tRNA modification, tRNA processing, tRNA wobble uridine modification; CC: cytoplasm, cytosol, elongator holoenzyme complex, nu... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Eif1ad | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Eif1ad in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Eif1ad (eukaryotic translation initiation factor 1A domain containing)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: RNA binding, translation initiation factor activity; CC: cytosol, nucleoplasm, nucleus
Pathways:
UniProt: Q3THJ3
Entrez ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | N6amt1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of N6amt1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: N6amt1 (N-6 adenine-specific DNA methyltransferase 1 (putative))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: arsonoacetate metabolic process, chromatin organization, methylation, negative regulation of gene expression, epigenetic, peptidyl-glutamine methylation,... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Pelo | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Pelo in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Pelo (pelota mRNA surveillance and ribosome rescue factor)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA surveillance, cell division, chromosome organization, endoderm development, inner cell mass cell proliferation, mesenchymal to epithelial transition, nonfu... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Nmnat1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Nmnat1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Nmnat1 (nicotinamide nucleotide adenylyltransferase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ATP generation from poly-ADP-D-ribose, NAD+ biosynthetic process, NAD+ biosynthetic process via the salvage pathway, negative regulation of DNA-templated transcrip... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Dis3 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Dis3 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Dis3 (DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: CUT catabolic process, RNA catabolic process, RNA processing, nuclear mRNA surveillance of mRNA 3'-end processing, nuclear-transcribed mRNA catabo... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ypel5 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ypel5 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ypel5 (yippee like 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: biological_process, cell population proliferation; MF: metal ion binding, molecular_function; CC: centrosome, cytoplasm, cytoskeleton, midbody, mitotic spindle pole, nucleus, spindle pole, ubiquit... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps13 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps13 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps13 (ribosomal protein S13)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, negative regulation of RNA splicing, ribosomal small subunit biogenesis, translation; MF: 5.8S rRNA binding, mRNA 5'-UTR binding, mRNA binding, small ribosomal sub... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Eif3c | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Eif3c in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Eif3c (eukaryotic translation initiation factor 3, subunit C)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translational initiation, formation of cytoplasmic translation initiation complex, translation, translational initiation; MF: RNA binding, ribos... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps6 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps6 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps6 (ribosomal protein S6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G1/S transition of mitotic cell cycle, T cell differentiation in thymus, T cell proliferation involved in immune response, TOR signaling, activation-induced cell death of T cells, cellular r... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl36a | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl36a in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl36a (ribosomal protein L36A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, translation, translation at postsynapse, translation at presynapse; MF: structural constituent of ribosome; CC: cytoplasm, cytosol, cytosolic large ribosomal sub... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps16 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps16 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps16 (ribosomal protein S16)
Type: protein-coding
Summary: A structural constituent of ribosome. Acts upstream of or within cellular response to leukemia inhibitory factor. Part of cytosolic small ribosomal subunit. Is active in synapse. Is expressed in early conceptus and secondary oocyte. Ortho... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Fau | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Fau in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Fau (FAU ubiquitin like and ribosomal protein S30 fusion)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: antibacterial humoral response, antimicrobial humoral immune response mediated by antimicrobial peptide, cytoplasmic translation, defense response to Gram-posit... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Eefsec | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Eefsec in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Eefsec (eukaryotic elongation factor, selenocysteine-tRNA-specific)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: selenocysteine incorporation, translation; MF: GTP binding, GTPase activity, hydrolase activity, metal ion binding, nucleotide binding, protein bindin... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Pwp1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Pwp1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Pwp1 (PWP1 homolog, endonuclein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chromatin organization, negative regulation of DNA-templated transcription, positive regulation of stem cell differentiation, positive regulation of transcription of nucleolar large rRN... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Wdr74 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Wdr74 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Wdr74 (WD repeat domain 74)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA metabolic process, blastocyst formation, rRNA processing, ribosomal large subunit biogenesis; CC: nuclear exosome (RNase complex), nucleolus, nucleoplasm, nucleus, preribosome, large sub... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps7 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps7 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps7 (ribosomal protein S7)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, negative regulation of ubiquitin-dependent protein catabolic process, neural crest cell differentiation, neural tube closure, positive regulation of gene expression,... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Polr2b | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Polr2b in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Polr2b (polymerase (RNA) II (DNA directed) polypeptide B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA-templated transcription, RNA-templated transcription, transcription by RNA polymerase II; MF: 5'-3' RNA polymerase activity, DNA binding, DNA-directed RNA p... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Slc25a26 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Slc25a26 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Slc25a26 (solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26)
Type: protein-coding
Summary: Predicted to enable S-adenosyl-L-methionine:S-adenosyl-L-homocysteine antiporter activity. Predicted to be involved in mitochondrial S-adenosyl-L-methionine transmembrane transpo... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Elp2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Elp2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Elp2 (elongator acetyltransferase complex subunit 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: proteasome assembly, regulation of receptor signaling pathway via JAK-STAT, tRNA processing, tRNA wobble uridine modification, transcription elongation by RNA polyme... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps29 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps29 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps29 (ribosomal protein S29)
Type: protein-coding
Summary: A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to act upstream of or within translation. Part of cytosolic small ribosomal subunit. Is expressed in several structures, including alimen... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rplp2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rplp2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rplp2 (ribosomal protein lateral stalk subunit P2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, cytoplasmic translational elongation, translation at postsynapse, translation at presynapse, translational elongation; MF: iron ion binding, r... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Fam204a | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Fam204a in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Fam204a (family with sequence similarity 204, member A)
Type: protein-coding
Summary: Orthologous to human FAM204A (family with sequence similarity 204 member A). [provided by Alliance of Genome Resources, Jul 2025]
Gene Ontology:
Pathways:
UniProt: Q8C6C7
Entr... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Pdap1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Pdap1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Pdap1 (PDGFA associated protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: cytosol, extracellular space, plasma membrane
Pathways: Immune System, Innate Immune System, Neutrophil degranulation
UniProt: Q3UHX2
Entrez ID: 231887 |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl15 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl15 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl15 (ribosomal protein L15)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, translation, translation at postsynapse, translation at presynapse; MF: RNA binding, structural constituent of ribosome; CC: A band, cytoplasm, cytosol, cytosolic ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Dhfr | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Dhfr in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Dhfr (dihydrofolate reductase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: axon regeneration, dTMP biosynthetic process, dihydrofolate metabolic process, folic acid metabolic process, one-carbon metabolic process, regulation of removal of superoxide radicals, re... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Xpo1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Xpo1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Xpo1 (exportin 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to salt, cellular response to triglyceride, intracellular protein transport, mRNA export from nucleus, mRNA transport, negative regulation of transcription by RNA polymerase II, nucl... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl26 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl26 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl26 (ribosomal protein L26)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, signal transduction by p53 class mediator, cellular response to ionizing radiation, cytoplasmic translation, positive regulation of intrinsic apoptotic signaling pathw... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Polg2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Polg2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Polg2 (polymerase (DNA directed), gamma 2, accessory subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA biosynthetic process, DNA repair, DNA replication, DNA-templated DNA replication, in utero embryonic development, mitochondrial DNA metabolic process, m... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps4x | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps4x in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps4x (ribosomal protein S4, X-linked)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, positive regulation of cell population proliferation, positive regulation of translation, ribosomal small subunit biogenesis, translation; MF: RNA binding... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Polr1b | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Polr1b in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Polr1b (polymerase (RNA) I polypeptide B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA-templated transcription, embryo implantation, neural crest formation, nucleologenesis, rRNA transcription; MF: 5'-3' RNA polymerase activity, DNA binding, DNA-directed RNA ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ctu2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ctu2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ctu2 (cytosolic thiouridylase subunit 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: protein urmylation, tRNA processing, tRNA thio-modification, tRNA wobble position uridine thiolation, tRNA wobble uridine modification; MF: nucleotidyltransferase activity, sulf... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl18 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl18 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl18 (ribosomal protein L18)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, translation; MF: RNA binding, structural constituent of ribosome; CC: cytoplasm, cytosol, cytosolic large ribosomal subunit, cytosolic ribosome, endoplasmic reticu... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Pcna | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Pcna in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Pcna (proliferating cell nuclear antigen)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, DNA replication, base-excision repair, gap-filling, cellular response to UV, cellular response to hydrogen peroxide, cellular response to xenob... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Emg1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Emg1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Emg1 (EMG1 N1-specific pseudouridine methyltransferase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: blastocyst development, methylation, nucleologenesis, rRNA base methylation, rRNA processing, ribosomal small subunit biogenesis, ribosome biogenesis; MF: RNA bin... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Sap130 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Sap130 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Sap130 (Sin3A associated protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: embryonic placenta development, in utero embryonic development, negative regulation of cell migration, negative regulation of stem cell population maintenance, negative regulation of t... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ddx21 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ddx21 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ddx21 (DExD box helicase 21)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: R-loop processing, chromatin remodeling, defense response to virus, immune system process, innate immune response, positive regulation of canonical NF-kappaB signal transduction, positive r... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Sbds | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Sbds in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Sbds (SBDS ribosome maturation factor)
Type: protein-coding
Summary: This gene encodes a protein that is necessary for ribosome function and maintaining normal levels of protein synthesis. The encoded protein may function to activate ribosomes for translation, and may be involved in cellular respo... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps15a | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps15a in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps15a (ribosomal protein S15A)
Type: protein-coding
Summary: A structural constituent of ribosome. Predicted to be involved in several processes, including positive regulation of cell population proliferation; response to virus; and ribosomal small subunit biogenesis. Located in mitochondrion. Pa... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Fxn | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Fxn in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Fxn (frataxin)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: [2Fe-2S] cluster assembly, [4Fe-4S] cluster assembly, adult walking behavior, aerobic respiration, cellular response to hydrogen peroxide, embryo development ending in birth or egg hatching, heme biosynt... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ppcs | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ppcs in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ppcs (phosphopantothenoylcysteine synthetase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: acetyl-CoA biosynthetic process, coenzyme A biosynthetic process, heart process; MF: ATP binding, identical protein binding, ligase activity, nucleotide binding, phosphopan... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Pak1ip1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Pak1ip1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Pak1ip1 (PAK1 interacting protein 1)
Type: protein-coding
Summary: Predicted to enable protein kinase inhibitor activity. Acts upstream of or within cell population proliferation and roof of mouth development. Located in nucleolus. Is expressed in several structures, including brain; chondrocraniu... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mrpl41 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mrpl41 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mrpl41 (mitochondrial ribosomal protein L41)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: apoptotic process, mitochondrial translation, translation; MF: structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial large ribosomal subunit, m... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl6 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl6 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl6 (ribosomal protein L6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, translation, translation at postsynapse, translation at presynapse; MF: 5.8S rRNA binding, RNA binding, mRNA binding, structural constituent of ribosome, tRNA bindin... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps11 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps11 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps11 (ribosomal protein S11)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, ribosomal small subunit biogenesis, translation, translation at postsynapse, translation at presynapse; MF: RNA binding, rRNA binding, structural constituent of ri... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Anapc11 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Anapc11 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Anapc11 (anaphase promoting complex subunit 11)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, anaphase-promoting complex-dependent catabolic process, cell division, positive regulation of mit... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl35 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl35 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl35 (ribosomal protein L35)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), translation, translation at postsynapse, translation at presynapse; MF: m... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Prdm10 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Prdm10 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Prdm10 (PR domain containing 10)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: positive regulation of DNA-templated transcription, positive regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, metal ion bind... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mtg2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mtg2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mtg2 (mitochondrial ribosome associated GTPase 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial large ribosomal subunit assembly, regulation of mitochondrial translation, regulation of respiratory system process, ribosome biogenesis; MF: GTP binding,... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Eif2s1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Eif2s1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Eif2s1 (eukaryotic translation initiation factor 2, subunit 1 alpha)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: HRI-mediated signaling, PERK-mediated unfolded protein response, cellular response to UV, cellular response to amino acid starvation, cellular respon... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Keap1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Keap1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Keap1 (kelch-like ECH-associated protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to carbohydrate stimulus, cellular response to interleukin-4, cellular response to oxidative stress, in utero embryonic development, negative regulation of ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ctdnep1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ctdnep1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ctdnep1 (CTD nuclear envelope phosphatase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: gamete generation, mesoderm development, nuclear envelope organization, positive regulation of canonical Wnt signaling pathway, positive regulation of triglyceride biosynthe... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rrp9 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rrp9 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rrp9 (ribosomal RNA processing 9, U3 small nucleolar RNA binding protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: rRNA processing, ribosomal small subunit biogenesis; MF: RNA binding, U3 snoRNA binding, snoRNA binding; CC: box C/D methylation guide snoRNP co... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Tmx2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Tmx2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Tmx2 (thioredoxin-related transmembrane protein 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: brain development; MF: disulfide oxidoreductase activity, identical protein binding; CC: endoplasmic reticulum, endoplasmic reticulum membrane, membrane, mitochondria-... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Tyms | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Tyms in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Tyms (thymidylate synthase)
Type: protein-coding
Summary: This gene encodes an enzyme that catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate as a cofactor. This function maintains the thymidine-5-prime monophosphate concentration critical for DNA ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Coa5 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Coa5 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Coa5 (cytochrome C oxidase assembly factor 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: leukocyte differentiation, mitochondrial cytochrome c oxidase assembly, multicellular organism growth, spleen development, thymus development; CC: mitochondrion
Pa... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps9 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps9 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps9 (ribosomal protein S9)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, ribosomal small subunit biogenesis, translation; MF: 5.8S rRNA binding, RNA binding, rRNA binding, structural constituent of ribosome; CC: cytoplasm, cytosol, cytoso... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl19 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl19 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl19 (ribosomal protein L19)
Type: protein-coding
Summary: A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to act upstream of or within translation. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expre... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Suds3 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Suds3 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Suds3 (suppressor of defective silencing 3 homolog (S. cerevisiae))
Type: protein-coding
Summary: Enables histone deacetylase binding activity and identical protein binding activity. Involved in negative regulation of DNA-templated transcription. Acts upstream of or within blastocyst hatching. Par... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Nmnat2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Nmnat2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Nmnat2 (nicotinamide nucleotide adenylyltransferase 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: 'de novo' NAD+ biosynthetic process from L-tryptophan, NAD+ biosynthetic process, NAD+ biosynthetic process via the salvage pathway, NADP+ biosynthetic process, cy... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ctu1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ctu1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ctu1 (cytosolic thiouridylase subunit 1)
Type: protein-coding
Summary: Predicted to enable tRNA binding activity. Predicted to be involved in tRNA wobble position uridine thiolation. Located in mitochondrion. Is expressed in brain. Orthologous to human CTU1 (cytosolic thiouridylase subunit 1). [pr... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Polr1e | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Polr1e in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Polr1e (polymerase (RNA) I polypeptide E)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA-templated transcription, RNA polymerase I preinitiation complex assembly, nucleolar large rRNA transcription by RNA polymerase I, transcription elongation by RNA polymerase... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl34 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl34 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl34 (ribosomal protein L34)
Type: protein-coding
Summary: A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation; translation at postsynapse; and translation at presynapse. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Is active in synapse. I... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl18a | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl18a in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl18a (ribosomal protein L18A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, translation; MF: structural constituent of ribosome; CC: cytoplasm, cytosol, cytosolic large ribosomal subunit, cytosolic ribosome, postsynaptic density, ribonuc... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Atad3a | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Atad3a in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Atad3a (ATPase family, AAA domain containing 3A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, HRI-mediated signaling, PERK-mediated unfolded protein response, antiviral innate immune response, mitochondrion organization, negative regulation o... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Grpel1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Grpel1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Grpel1 (GrpE-like 1, mitochondrial)
Type: protein-coding
Summary: Predicted to enable several functions, including ATPase binding activity; adenyl-nucleotide exchange factor activity; and unfolded protein binding activity. Predicted to be involved in protein import into mitochondrial matrix. Locat... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Tut1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Tut1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Tut1 (terminal uridylyl transferase 1, U6 snRNA-specific)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA 3'-end processing, RNA metabolic process, U6 snRNA 3'-end processing, co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway, histo... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Eif3h | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Eif3h in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Eif3h (eukaryotic translation initiation factor 3, subunit H)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translational initiation, formation of cytoplasmic translation initiation complex, negative regulation of proteasomal ubiquitin-dependent protei... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps24 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps24 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps24 (ribosomal protein S24)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, erythrocyte homeostasis, rRNA processing, ribosomal small subunit biogenesis, translation, translation at postsynapse, translation at presynapse; MF: structural co... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Cycs | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Cycs in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Cycs (cytochrome c, somatic)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: apoptotic process, hydrogen peroxide metabolic process, intrinsic apoptotic signaling pathway, mitochondrial electron transport, cytochrome c to oxygen, mitochondrial electron transport, ub... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Elp6 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Elp6 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Elp6 (elongator acetyltransferase complex subunit 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: apoptotic process, autophagosome maturation, autophagy, cellular response to stress, homeostasis of number of retina cells, inflammasome-mediated signaling pathway, ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Cdc23 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Cdc23 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Cdc23 (CDC23 cell division cycle 23)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: anaphase-promoting complex-dependent catabolic process, cell division, mitotic cell cycle, mitotic metaphase chromosome alignment, positive regulation of mitotic metaphase/anaphase ... |
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