Evalutation
Collection
7 items • Updated
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From March 2007 to January 2011, 88 DBE procedures were performed on 66 patients. Indications included evaluation anemia/gastrointestinal bleed, small bowel IBD and dilation of strictures. Video-capsule endoscopy (VCE) was used prior to DBE in 43 of the 66 patients prior to DBE evaluation. The mean age was 62 years. Th... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Halofantrine is a newly developed antimalarial drug used for the treatment of Plasmodium falciparum malaria. The introduction of this drug has been delayed because of its possible side effects, and due to insufficient studies on adverse reactions in humans. There have been no studies investigating its effect on hearing... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Telephone counseling and tailored print communications have emerged as promising methods for promoting mammography screening. However, there has been little research testing, within the same randomized field trial, of the efficacy of these two methods compared to a high-quality usual care system for enhancing screening... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Electronic health records have the potential to facilitate family history use by primary care physicians (PCPs) to provide personalized care. The objective of this study was to determine whether automated, at-the-visit tailored prompts about family history risk change PCP behavior. Automated, tailored prompts highlight... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
We have previously reported the feasibility of diagnostic and therapeutic peritoneoscopy including liver biopsy, gastrojejunostomy, and tubal ligation by an oral transgastric approach. We present results of per-oral transgastric splenectomy in a porcine model. The goal of this study was to determine the technical feasi... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
We evaluated the usefulness of a short stay or 23-hour ward in a pediatric unit of a large teaching hospital, Westmead Hospital, and an academic Children's hospital, The New Children's Hospital, to determine if they are a useful addition to the emergency service. This is a descriptive comparison of prospectively collec... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Anchoring vignettes are brief texts describing a hypothetical character who illustrates a certain fixed level of a trait under evaluation. This research uses vignettes to elucidate factors associated with sleep disorders in adult Japanese before and after adjustment for reporting heterogeneity in self-reports. This stu... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
The objective of the current study is to determine to what extent the reduction of Chile's traffic fatalities and injuries during 2000-2012 was related to the police traffic enforcement increment registered after the introduction of its 2005 traffic law reform. A unique dataset with assembled information from public in... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
To examine patterns of knowledge and attitudes among adults aged>65 years unvaccinated for influenza. Surveyed Medicare beneficiaries in 5 areas; clustered unvaccinated seniors by their immunization related knowledge and attitudes. Identified 4 clusters: Potentials (45%) would receive influenza vaccine to prevent disea... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Synchronous liver metastases (SLM) occur in 20% of colorectal cancers (CRC). Resection of SLM and CLC can be undertaken at different centres (separate management, SM) or at the same centre (global management, GM). Retrospective study of SLM and CRC resections carried out during 01/2000 - 12/2006 by SM or GM, using a co... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
PRISM is claimed to score disease severity which has attributed an impact on length of PICU stay (LOS). To determine the impact of PRISM on LOS, and evaluate an Artificial Neural Network's (ANN) performance to estimate LOS from PRISM item patterns. Retrospectively we performed correlation and regression analyses on rou... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
To determine the relationship between injury severity surrogates and other patient factors with the development and severity of heterotopic ossification (HO) following open reduction internal fixation of acetabular fractures treated with a posterior approach. Retrospective review. Academic level 1 trauma center. Two hu... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | maybe | C |
The use of a balloon expandable stent valve includes balloon predilatation of the aortic stenosis before valve deployment. The aim of the study was to see whether or not balloon predilatation is necessary in transcatheter aortic valve replacement (TAVI). Sixty consecutive TAVI patients were randomized to the standard p... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
The incidence of large-scale urban attacks on civilian populations has significantly increased across the globe over the past decade. These incidents often result in Hospital Multiple Casualty Incidents (HMCI), which are very challenging to hospital teams. 15 years ago the Emergency and Disaster Medicine Division in th... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
The transanal endorectal pull-through (TERPT) is becoming the most popular procedure in the treatment of Hirschsprung disease (HD), but overstretching of the anal sphincters remains a critical issue that may impact the continence. This study examined the long-term outcome of TERPT versus conventional transabdominal (AB... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
Emergency surgery is associated with poorer outcomes and higher mortality with recent studies suggesting the 30-day mortality to be 14-15%. The aim of this study was to analyse the 30-day mortality, age-related 30-day mortality and 1-year mortality following emergency laparotomy. We hope this will encourage prospective... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | maybe | C |
Comorbid major depression (MD) and alcohol use disorder (AUD), particularly in adolescents, have been shown to be associated with poorer subsequent MD outcomes. Longitudinal data were used to model associations between a four-level classification of MD/AUD during the period 15-18 years (neither; MD-only; AUD-only; como... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
Specific markers for differentiation of nonalcoholic (NASH) from alcoholic steatohepatitis (ASH) are lacking. We investigated the role of routine laboratory parameters in distinguishing NASH from ASH. Liver biopsies performed at our hospital over a 10-year period were reviewed, 95 patients with steatohepatitis identifi... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Studies have shown that schizophrenia patients have motion perception deficit, which was thought to cause eye-tracking abnormality in schizophrenia. However, eye movement closely interacts with motion perception. The known eye-tracking difficulties in schizophrenia patients may interact with their motion perception. Tw... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Kidneys from elderly donors tend to be implanted in recipients who are also elderly. We present the results obtained after 10 years of evolution on transplanting elderly kidneys into young recipients. Ninety-one consecutive transplants are studied, carried out in our center with kidneys from cadaver donors older than 6... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Voluntary asphyxiation among children, preteens, and adolescents by hanging or other means of inducing hypoxia/anoxia to enhance sexual excitement is not uncommon and can lead to unintended death. This study addresses autoerotic asphyxiation (AEA) with the intent of increasing pediatricians' knowledge of the syndrome a... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Radiotherapy reduces local recurrence rates but is also capable of short- and long-term toxicity. It may also render treatment of local recurrence more challenging if it develops despite previous radiotherapy. This study examined the impact of radiotherapy for the primary rectal cancer on outcomes after pelvic exentera... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
To characterize the use and delivery of cough and cold medicines in children younger than 6 presenting to an inner-city pediatric emergency department (PED) following 2007 FDA warnings. A cross-sectional observational study was performed using a convenience sampling of PED patients during the fall of 2010. Caregivers w... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Trauma patients who require therapeutic anticoagulation pose a difficult treatment problem. The purpose of this study was to determine: (1) the incidence of complications using therapeutic anticoagulation in trauma patients, and (2) if any patient factors are associated with these complications. An 18-month retrospecti... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
To assess the extent to which the title and font of participant information sheets (PISs) can influence pregnant women's and trainee midwives' perceptions of an antenatal intervention. Pregnant women (n=35) and trainee midwives (n=36) were randomly presented with one of four PISs where the title and font of the PIS had... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Accurate and updated information on airborne pollen in specific areas can help allergic patients. Current monitoring systems are based on a morphologic identification approach, a time-consuming method that may represent a limiting factor for sampling network enhancement. To verify the feasibility of developing a real-t... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Although observational data support an inverse relationship between high-density lipoprotein (HDL) cholesterol and coronary heart disease (CHD), genetic HDL deficiency states often do not correlate with premature CHD. Carotid intima-media thickness (cIMT) measurements were obtained in cases comprising 10 different muta... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
One of the sites most frequently invaded by gastric cancer is the mesocolon; however, the UICC does not mention this anatomical site as an adjacent structure involved in gastric cancer. The purpose of this study was to characterize and classify mesocolon invasion from gastric cancer. We examined 806 patients who underw... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | maybe | C |
Changes in the spectrum of general surgery and the delivery of surgical care have placed the requirement for a mandatory general surgery rotation in the surgical clerkship in question. We tested the hypothesis that equal mastery of surgical clerkship objectives can be obtained in a clerkship with and without general su... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
To assess and compare the value of split-liver transplantation (SLT) and living-related liver transplantation (LRT). The concept of SLT results from the development of reduced-size transplantation. A further development of SLT, the in situ split technique, is derived from LRT, which itself marks the optimized outcome i... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Sternal fractures in childhood are rare. The aim of the study was to investigate the accident mechanism, the detection of radiological and sonographical criteria and consideration of associated injuries. In the period from January 2010 to December 2012 all inpatients and outpatients with sternal fractures were recorded... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | maybe | C |
Recent years have seen a rapid proliferation of emergency ultrasound (EUS) programs in the United States. To date, there is no evidence supporting that EUS fellowships enhance residents' ultrasound (US) educational experiences. The purpose of this study was to determine the impact of EUS fellowships on emergency medici... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
To assess if the Hawkins sign can predict whether or not astragalus fractures of the neck will develop avascular necrosis. It is also assessed whether the occurrence of this complication is related to the displacement of the fracture, soft tissue injury, or delay in the reduction or surgery. The results were compared w... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | maybe | C |
The purpose of this study is to examine whether or not well differentiated (w-d) hepatocellular carcinoma (HCC) is indeed clinically early cancer. Seventy six patients with solitary small HCCs up to 3 cm in diameter, who underwent hepatectomy, were observed for at least 2 years for possible recurrence. These patients w... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
Recent evaluations of IT innovations in primary care have highlighted variations between centres and practices in uptake and use. We evaluated whether structural characteristics of a general practice were associated with variations in use of a web-based clinical information system underpinning a Managed Clinical Networ... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
Breathlessness is one of the most distressing symptoms experienced by patients with advanced cancer and noncancer diagnoses alike. Often, severity of breathlessness increases quickly, calling for rapid symptom control. Oral, buccal, and parenteral routes of provider-controlled drug administration have been described. I... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
With the advancement of an aging society in the world, an increasing number of elderly patients have been hospitalized due to aneurysmal subarachnoid hemorrhage (aSAH). There is no study that compares the elderly cases of aSAH who receive the definitive treatment with those who treated conservatively. The aim of this s... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Measurement of visceral adipose tissue (VAT) needs to be accurate and sensitive to change for risk monitoring. The purpose of this study is to determine the CT slice location where VAT area can best reflect changes in VAT volume and body weight. 60 plain abdominal CT images from 30 males [mean age (range) 51 (41-68) ye... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
The records of 465 patients with an established diagnosis of age related macular degeneration who had attended a specialist macular clinic between 1990 and 1998 were scrutinised. A full clinical examination and standardised refraction had been carried out in 189 of these cases on a minimum of two occasions. Cases were ... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
Pterygium is a disease of unknown origin and pathogenesis that might be vision threatening. It is characterised by a wing-like conjunctival overgrowth of the cornea. Several studies have investigated human papillomavirus (HPV) as a risk factor for the development of pterygia, but the results are inconclusive.AIM: To in... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | maybe | C |
The accepted treatment protocol for necrotizing fasciitis (NF) consists of extensive surgery and wide spectrum antibiotics. Hyperbaric oxygenation (HBO) has been recommended as adjuvant therapy for NF, improving patient mortality and outcome. However, the beneficial effect of HBO for NF remains controversial. A retrosp... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
(i) To examine the association between self-reported mechanical factors and chronic oro-facial pain. (ii) To test the hypothesis that this relationship could be explained by: (a) reporting of psychological factors, (b) common association of self-reported mechanical factors with other unexplained syndromes. A population... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
To investigate the effectiveness of acupuncture in treating phonotraumatic vocal fold lesions.STUDY DESIGN/ A total of 123 dysphonic individuals with benign vocal pathologies were recruited. They were given either genuine acupuncture (n = 40), sham acupuncture (n = 44), or no treatment (n = 39) for 6 weeks (two 30-minu... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Elevated resting heart rate (RHR) is a neglected marker in cardiovascular risk factor studies of sub-Saharan African populations. This study aimed to determine the prevalence of elevated RHR and other risk factors for cardiovascular disease (CVD) and to investigate any associations between RHR and these risk factors in... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Programmed cell death (PCD) is the regulated death of cells within an organism. The lace plant (Aponogeton madagascariensis) produces perforations in its leaves through PCD. The leaves of the plant consist of a latticework of longitudinal and transverse veins enclosing areoles. PCD occurs in the cells at the center of ... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Social and cultural factors combined with little information may prevent the diffusion of epidural analgesia for pain relief during childbirth. The present study was launched contemporarily to the implementation of analgesia for labor in our Department in order to perform a 2 years audit on its use. The goal is to eval... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
To describe the biomechanical and wound healing characteristics of corneas after excimer laser keratorefractive surgery. Histologic, ultrastructural, and cohesive tensile strength evaluations were performed on 25 normal human corneal specimens, 206 uncomplicated LASIK specimens, 17 uncomplicated sub-Bowman's keratomile... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Compared with computed tomography (CT) and magnetic resonance imaging (MRI), positron emission tomography (PET) may have additional value in the assessment of primary and recurrent cervical cancer. However, the degree of tumour uptake of (18)F-2-fluoro-2-deoxy-D: -glucose (FDG) uptake is sometimes influenced by diabete... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
Apparent life-threatening events in infants are a difficult and frequent problem in pediatric practice. The prognosis is uncertain because of risk of sudden infant death syndrome. Eight infants aged 2 to 15 months were admitted during a period of 6 years; they suffered from similar maladies in the bath: on immersion, t... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
In primary and secondary prevention trials, statins have been shown to reduce the risk of stroke. In addition to lipid lowering, statins have a number of antiatherothrombotic and neuroprotective properties. In a preliminary observational study, we explored whether clinical outcome is improved in patients who are on tre... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
Assessment of visual acuity depends on the optotypes used for measurement. The ability to recognize different optotypes differs even if their critical details appear under the same visual angle. Since optotypes are evaluated on individuals with good visual acuity and without eye disorders, differences in the lower visu... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
Extracranial internal carotid artery stenosis is a risk factor for perioperative stroke in patients undergoing coronary artery bypass surgery (CAB). Although selective and non-selective methods of preoperative carotid screening have been advocated, it remains unclear if this screening is clinically relevant.AIM: To tes... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
Immediate breast reconstruction (IBR) provides psychological benefit to many early breast cancer patients however concerns persist regarding its potential impact on chemotherapy delivery. We investigated the association between IBR, complications and adjuvant chemotherapy delivery. Retrospective analysis of patients in... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
Fournier's gangrene is known to have an impact in the morbidity and despite antibiotics and aggressive debridement, the mortality rate remains high. To assess the morbidity and mortality in the treatment of Fournier's gangrene in our experience. The medical records of 14 patients with Fournier's gangrene who presented ... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
For women, the correlation between circulating androgens and sexual desire is inconclusive. Substitution with androgens at physiological levels improves sexual function in women who experience decreased sexual desire and androgen deficiency from surgical menopause, pituitary disease, and age-related decline in androgen... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
To compare adherence to follow-up recommendations for colposcopy or repeated Papanicolaou (Pap) smears for women with previously abnormal Pap smear results. Retrospective cohort study. Three northern California family planning clinics. All women with abnormal Pap smear results referred for initial colposcopy and a rand... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
To examine the ability of various postoperative nomograms to predict prostate cancer-specific mortality (PCSM) and to validate that they could predict aggressive biochemical recurrence (BCR). Prostate-specific antigen (PSA), grade, and stage are the classic triad used to predict BCR after radical prostatectomy (RP). Mu... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Secondhand smoke exposure (SHSe) threatens fragile infants discharged from a neonatal intensive care unit (NICU). Smoking practices were examined in families with a high respiratory risk infant (born at very low birth weight; ventilated>12 hr) in a Houston, Texas, NICU. Socioeconomic status, race, and mental health sta... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Lymphedema may be identified by simpler circumference changes as compared with changes in limb volume. Ninety breast cancer patients were prospectively enrolled in an academic trial, and seven upper extremity circumferences were measured quarterly for 3 years. A 10% volume increase or greater than 1 cm increase in arm ... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | maybe | C |
Bystander resuscitation plays an important role in lifesaving cardiopulmonary resuscitation (CPR). A significant reduction in the "no-flow-time", quantitatively better chest compressions and an improved quality of ventilation can be demonstrated during CPR using supraglottic airway devices (SADs). Previous studies have... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
To evaluate the impact of HER2 immunoreactivity on clinical outcome in locally advanced urothelial carcinoma patients who received surgery alone, or methotrexate, vinblastine, epirubicin, and cisplatin (M-VEC) as adjuvant chemotherapy. We studied 114 formalin-fixed paraffin-embedded specimens obtained from locally adva... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | maybe | C |
The purpose of this study was to delineate early respiratory predictors of mortality in children with hemato-oncology malignancy who developed acute respiratory distress syndrome (ARDS). We conducted a retrospective chart review of children with malignant and ARDS who needed mechanical ventilation and were admitted to ... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
To determine the impact of Florida's Medicaid Demonstration 4 years post-implementation on per member per month (PMPM) Medicaid expenditures and whether receiving care through HMOs versus provider service networks (PSNs) in the Demonstration was associated with PMPM expenditures.DATA: Florida Medicaid claims from two f... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Although the retroperitoneal approach has been the preferred choice for open urological procedures, retroperitoneoscopy is not the preferred approach for laparoscopy. This study aims to develop a training model for retroperitoneoscopy and to establish an experimental learning curve. Fifteen piglets were operated on to ... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
The aim of this work is to assess a previously described slit-lamp biomicroscopy-based method (SLBM) for measuring pupil diameter and compare it to Colvard infrared pupillometry (CIP). Two examiners performed three repeated measurements with each instrument in 40 healthy eyes. We determined the agreement of SLBM and CI... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
To evaluate prepuce development and retractibility in a group of boys. To point out the value of circumcision and prepucial forced dilation during childhood. Prepuce development and retractibility were evaluated in 400 boys ages between 0-16 year old. In boys under 1 year prepuce retractibility (assessed only in childr... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
Medical records of 220 patients hospitalized for acute diverticulitis between June 1, 2002 and September 1, 2009 were reviewed. Acute diverticulitis was diagnosed by clinical criteria and characteristic CT findings. Fifteen patients were excluded either because of questionable CT or hematochezia. Mean age was 61.8±14.3... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
To investigate whether problems in instrumental activities of daily living (IADL) can add to conventionally used clinical measurements in helping to predict a diagnosis of dementia at 1- and 2-year follow-up. Multicenter prospective cohort study. Memory clinics in Europe. Individuals aged 55 and older without dementia.... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
To compare children's, parents' and physicians' perceptions of children's body size. We administered a structured questionnaire of body size perception using a descriptive Likert scale keyed to body image figures to children ages 12 to 18 years. The same scale was given to parents of children ages 5 to 18 years. The sa... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
The relationship between the use of an endoscope during ventriculoperitoneal shunt (VPS) procedures and infection remains poorly defined. In this study, we sought to analyze whether the simultaneous use of an endoscope could in fact increase the infection rate associated with VPS procedures. This study included 438 VPS... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
Multiple sclerosis (MS) is an immune-mediated inflammatory demyelinating disease of uncertain etiology. Although the mechanisms of inducting autoimmunity by some of the infectious agents have been investigated, there is not yet enough research on streptococcal infections.MATERIAL/ To understand the effect of past group... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
In a prospective study 218 preschool children were enrolled (stratified in 2 training programs, one specialized for phonologic awareness in order to prevent dyslexia, the other consisting in training of general perception) during the last year of kindergarten. After finishing the first grade 131 children were compared ... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | maybe | C |
The endogenous estradiol metabolite, 2-methoxyestradiol (2ME), has been shown to be a potent inhibitor of cell growth and a strong anti-angiogenic substance. We investigated for the first time whether in vitro combinations of 2ME with various chemotherapeutic compounds may result in an additive inhibitory effect on the... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
There are a number of factors responsible for the longevity of unicompartmental knee replacements (UKR). These include the magnitude of postoperative alignment and the type of material used. The effect of component design and material on postoperative alignment, however, has not been explored. We retrospectively review... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Reconstructing the natural joint line in knee revision surgery improves clinical and functional outcome but may be challenging when both cartilage and bone were removed during previous operations. Assessing joint lines (JLs) by means of bony landmarks is inadvisable because of large variations in human anatomy. Because... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
To determine whether there is a relationship between VEGF expression and renal vein and vena cava invasion in stage pT3 renal cell carcinoma and to evaluate the impact of VEGF expression on survival in pT3 renal cell carcinoma. 78 patients with a pT3a or pT3b tumour without vena cava invasion or pT3b tumour with vena c... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | maybe | C |
Deaths from injury and poisoning (suicide, accidents, undetermined deaths, and homicide) are the major cause of death among young men aged 15-39 years in England and Wales and have been increasing in recent years.AIM: To describe common characteristics among young men who die from injury and poisoning. We employed a re... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
The objective of the study was to determine whether risk of recurrent preterm birth differs based on the clinical presentation of a prior spontaneous preterm birth (SPTB): advanced cervical dilatation (ACD), preterm premature rupture of membranes (PPROM), or preterm labor (PTL). This retrospective cohort study included... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
It is unclear whether traveling long distances to high-volume centers would compensate for travel burden among patients undergoing rectal cancer resection. The purpose of this study was to determine whether operative volume outweighs the advantages of being treated locally by comparing the outcomes of patients with rec... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
The pressures delivered by autotitrating continuous positive airways pressure (CPAP) devices not only treat obstructive sleep apnoea (OSA) effectively but also give potentially interesting physiological information about the forces impinging on the pharynx. In earlier work from this unit, we used correlations between a... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Treatment of neonatal testicular torsion has two objectives: salvage of the involved testicle (which is rarely achieved) and preservation of the contralateral gonad. The second goal universally involves contralateral testicular scrotal fixation to prevent the future occurrence of contralateral torsion. However, there i... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | maybe | C |
To assess the outcomes of patients with nasopharyngeal carcinoma (NPC) whose treatment was determined by computerized tomography (CT) and/or magnetic resonance imaging staging and to analyze the impact of induction chemotherapy and accelerated fractionated radiotherapy. The analysis is based on 122 of 143 previously un... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
To determine the duration of continuing pregnancy after antenatal corticosteroid (AC) administration and to evaluate the potential opportunity for rescue AC. Retrospective analysis of women at 24-32 weeks' gestation who received AC at one institution. Six hundred ninety-two women received AC. Two hundred forty-seven (3... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | maybe | C |
To assess the impact of the comprehensive HIV/STD Control Program established in Jamaica since the late 1980s on the HIV/AIDS epidemic. AIDS case reports, HIV testing of blood donors, antenatal clinic attenders (ANC), food service workers, sexually transmitted disease (STD) clinic attenders, female prostitutes, homosex... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
It is commonly accepted that pathological gambling results from the interaction of multiple risk factors. Among these, dopamine replacement therapy (DRT) prescribed for Parkinson disease can be cited. Another dopamine agonist, aripiprazole, could be a new risk factor. We decided to explore this potential adverse drug r... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
To determine the practices and knowledge of harmful effects regarding use of Chaalia and Pan Masala in three schools of Mahmoodabad and Chanesar Goth, Jamshed Town, Karachi, Pakistan. To achieve the objective a cross-sectional design was used in three government schools of Mahmoodabad and Chanesar Goth, Jamshed Town, K... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
The technique of induced sputum has allowed to subdivide asthma patients into inflammatory phenotypes according to their level of granulocyte airway infiltration. There are very few studies which looked at detailed sputum and blood cell counts in a large cohort of asthmatics divided into inflammatory phenotypes. The pu... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | maybe | C |
The purpose of this study is to measure the accuracy and reliability of normally sighted, visually impaired, and blind pedestrians at making street crossing decisions using visual and/or auditory information. Using a 5-point rating scale, safety ratings for vehicular gaps of different durations were measured along a tw... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | maybe | C |
Tinnitus can be related to many different aetiologies such as hearing loss or a noise trauma, but it can also be related to the somatosensory system of the cervical spine, called cervicogenic somatic tinnitus (CST). Case studies suggest a positive effect of cervical spine treatment on tinnitus complaints in patients wi... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Using murine models, we have shown that the lysosomotropic amine, chloroquine, is effective in the prevention of graft-versus-host disease (GVHD) mediated by donor T cells reactive with recipient minor histocompatibility antigens (MiHCs). Because lysosomotropic amines can suppress major histocompatibility complex (MHC)... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Little is known about the validity and reliability of expert assessments of the quality of antimicrobial prescribing, despite their importance in antimicrobial stewardship. We investigated how infectious disease doctors' assessments compared with a reference standard (modal expert opinion) and with the assessments of t... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
Impaired fasting glucose (IFG) below the diagnostic threshold for diabetes mellitus (DM) is associated with macrovascular pathology and increased mortality after percutaneous coronary interventions. The study goal was to determine whether pre-operative fasting blood glucose (fB-glu) is associated with an increased mort... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
The influence of positron emission tomography in the management of recurrent rectal cancer is well established but its role in primary rectal cancer remains uncertain. This study therefore prospectively assesses the impact of position emission tomography scanning on the management of primary rectal cancer. Forty-six pa... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
The morbidity and mortality associated with Panton-Valentine leucocidin (PVL)-positive Staphylococcus aureus suggest that this toxin is a key marker of disease severity. Nevertheless, the importance of PVL in the pathogenesis of primary bacteraemia caused by S. aureus is uncertain. We have determined the prevalence of ... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | maybe | C |
A short course of systemic corticosteroids is an important therapy in the treatment of pediatric asthma exacerbations. Although a 5-day course of oral prednisone or prednisolone has become the most commonly used regimen, dexamethasone has also been used for a shorter duration (1-2 days) with potential for improvement i... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
To explain China's cigarette pricing mechanism and the role of the Chinese State Tobacco Monopoly Administration (STMA) on cigarette pricing and taxation. Published government tobacco tax documentation and statistics published by the Chinese STMA are used to analyse the interrelations among industry profits, taxes and ... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
Sulfasalazine is a widely used anti-inflammatory agent in the treatment of inflammatory bowel disease and several rheumatological disorders. Although as many as 20% of treated patients may experience reversible, dose-dependent side effects, less frequent but potentially severe, systemic reactions have also been reporte... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | maybe | C |
One of the problems with manual resuscitators is the difficulty in achieving accurate volume delivery. The volume delivered to the patient varies by the physical characteristics of the person and method. This study was designed to compare tidal volumes delivered by the squeezing method, physical characteristics and edu... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | no | B |
To explore whether electrochemiluminescence (ECL) assays can help improve prediction of time to type 1 diabetes in the TrialNet autoantibody-positive population. TrialNet subjects who were positive for one or more autoantibodies (microinsulin autoantibody, GAD65 autoantibody [GADA], IA-2A, and ZnT8A) with available ECL... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
We observed an endoscopic abnormally in a group of children with histological esophagitis. We termed this finding "vertical lines in esophageal mucosa" (VLEM). We examined the relationship between the presence of VLEM and significant histologic changes in esophageal mucosal biopsies. Between January 1, 1992, and August... | {
"A": "yes",
"B": "no",
"C": "maybe"
} | yes | A |
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