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TCGA-AO-A0JB | TCGA-BRCA | 6,481,524,938,623,040,000 | 3,598,391,053,150,423,000 | train | mcq | from_caption | caption_radiology | radiology_findings | all_available | true | true | true | true | Which radiology finding best matches this case? | Upper-central breast irregular heterogeneous enhancing mass with adjacent small enhancing foci or contiguous extension. | Irregular spiculated stellate breast mass with heterogeneous enhancement and small adjacent enhancing foci near superficial vessels. | Deep posterior irregular enhancing focus/small mass with adjacent nonmass enhancement extending along fibroglandular tissue; nearby additional enhancing foci. | Irregular noncircumscribed enhancing focus with internal heterogeneity and variable conspicuity across slices, giving a suspicious infiltrative appearance. | Irregular spiculated stellate breast mass with heterogeneous enhancement and small adjacent enhancing foci near superficial vessels. | B | TCGA-AO-A0JB | condensed_caption:radiology_findings | [
"data/features/features_uni/TCGA-AO-A0JB-01Z-00-DX1.250FE098-345B-4981-9236-0519E1C9058E.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk3/pngs/TCGA-BRCA/TCGA-AO-A0JB/1.3.6.1.4.1.14519.5.2.1.9203.4002.576998191521675502525281307152/1.3.6.1.4.1.14519.5.2.1.9203.4002.108867266986411861894751497504",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_cpgpt_dnam/TCGA-BRCA/TCGA-AO-A0JB-01A__6715f318-34ad-40ec-8ea4-06d356dddb1f.pt | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-AO-A0JB__2a09e101-9e01-45ec-9b02-d806f4cd7469.pt | |||||
TCGA-AO-A0JB | TCGA-BRCA | 4,471,394,947,830,224,400 | 3,542,895,442,570,343,400 | train | mcq | from_caption | caption_pathology | pathology_findings | all_available | true | true | true | true | Which pathology finding best matches this case? | Low-cellularity discohesive cells and thin linear cords infiltrate densely fibrotic stroma, with limited tubules and no solid nests. | Scirrhous infiltrative carcinoma with irregular angulated glands, cords, and small nests in abundant desmoplastic stroma near adipose edge. | Invasive nests, cords, and angulated tubules in collagenized desmoplastic stroma, extending through fibrous tissue into adipose with blood-filled spaces. | Predominantly solid-vaguely nested infiltrative carcinoma in desmoplastic stroma, traversing fibroadipose tissue with entrapped adipocytes and patchy lymphoid infiltrates. | Invasive nests, cords, and angulated tubules in collagenized desmoplastic stroma, extending through fibrous tissue into adipose with blood-filled spaces. | C | TCGA-AO-A0JB | condensed_caption:pathology_findings | [
"data/features/features_uni/TCGA-AO-A0JB-01Z-00-DX1.250FE098-345B-4981-9236-0519E1C9058E.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk3/pngs/TCGA-BRCA/TCGA-AO-A0JB/1.3.6.1.4.1.14519.5.2.1.9203.4002.576998191521675502525281307152/1.3.6.1.4.1.14519.5.2.1.9203.4002.108867266986411861894751497504",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_cpgpt_dnam/TCGA-BRCA/TCGA-AO-A0JB-01A__6715f318-34ad-40ec-8ea4-06d356dddb1f.pt | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-AO-A0JB__2a09e101-9e01-45ec-9b02-d806f4cd7469.pt | |||||
TCGA-AO-A0JB | TCGA-BRCA | 6,464,119,359,609,760,000 | 6,718,125,695,957,294,000 | train | mcq | from_caption | caption_genomics | genomic_findings | all_available | true | true | true | true | Which genomic finding best matches this case? | LumB with high ESR1/PGR/FOXA1/GATA3, high ESR1 promoter methylation, mutation-panel wild type, copy-number neutral, low TMB. | Basal-like TP53/PTEN-mutant, PIK3CA/GATA3/MAP3K1/CDH1 wild-type, copy-number quiet, low-TMB, low-HRD, HR-proficient-like profile. | TP53 p.R213* truncation with otherwise copy-number-neutral, low-TMB genomically quiet LumB/normal-like discordant luminal-expression profile. | PIK3CA H1047R with TP53 L194R and NF1 splice-site loss; HER2-enriched transcriptome, high ERBB2, ESR1/BRCA1 promoter methylation. | TP53 p.R213* truncation with otherwise copy-number-neutral, low-TMB genomically quiet LumB/normal-like discordant luminal-expression profile. | C | TCGA-AO-A0JB | condensed_caption:genomic_findings | [
"data/features/features_uni/TCGA-AO-A0JB-01Z-00-DX1.250FE098-345B-4981-9236-0519E1C9058E.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk3/pngs/TCGA-BRCA/TCGA-AO-A0JB/1.3.6.1.4.1.14519.5.2.1.9203.4002.576998191521675502525281307152/1.3.6.1.4.1.14519.5.2.1.9203.4002.108867266986411861894751497504",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_cpgpt_dnam/TCGA-BRCA/TCGA-AO-A0JB-01A__6715f318-34ad-40ec-8ea4-06d356dddb1f.pt | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-AO-A0JB__2a09e101-9e01-45ec-9b02-d806f4cd7469.pt | |||||
TCGA-AO-A0JB | TCGA-BRCA | 8,946,693,839,538,963,000 | 7,208,833,406,086,384,000 | train | mcq | from_caption | caption_integrated | integrated_interpretation | all_available | true | true | true | true | Which integrated interpretation best matches this case? | Compact irregular mass matches invasive stromal-adipose infiltration; lymphoid-rich necrotic histology and basal-like TP53-altered biology distinguish this case. | Cohesive nested invasive carcinoma with desmoplasia paired to genomically quiet AKT1-driven luminal A biology. | Metaplastic keratinizing non-luminal carcinoma with squamous differentiation, stromal hyalinization/inflammation, and combined PI3K activation plus TP53 loss. | Infiltrative spiculated multifocal-appearing breast carcinoma with stromal adipose invasion and isolated TP53 loss on an otherwise quiet luminal program. | Infiltrative spiculated multifocal-appearing breast carcinoma with stromal adipose invasion and isolated TP53 loss on an otherwise quiet luminal program. | D | TCGA-AO-A0JB | condensed_caption:integrated_interpretation | [
"data/features/features_uni/TCGA-AO-A0JB-01Z-00-DX1.250FE098-345B-4981-9236-0519E1C9058E.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk3/pngs/TCGA-BRCA/TCGA-AO-A0JB/1.3.6.1.4.1.14519.5.2.1.9203.4002.576998191521675502525281307152/1.3.6.1.4.1.14519.5.2.1.9203.4002.108867266986411861894751497504",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_cpgpt_dnam/TCGA-BRCA/TCGA-AO-A0JB-01A__6715f318-34ad-40ec-8ea4-06d356dddb1f.pt | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-AO-A0JB__2a09e101-9e01-45ec-9b02-d806f4cd7469.pt | |||||
TCGA-AO-A0JM | TCGA-BRCA | 5,511,846,645,320,374,000 | 502,773,002,361,197,700 | train | mcq | from_caption | caption_radiology | radiology_findings | all_available | true | true | true | true | Which radiology finding best matches this case? | Small enhancing breast mass limited to sampled slices, with surrounding parenchymal distortion. | Large ROI-spanning asymmetric regional enhancement with patchy internal high-signal foci and irregular non-circumscribed configuration. | Right upper outer/anterior breast focal nonmass-like to irregular heterogeneous enhancement across adjacent slices near lateral soft tissues. | Irregular heterogeneous enhancing breast mass with adjacent linear branching enhancement and infiltrative extension into fibroglandular tissue. | Irregular heterogeneous enhancing breast mass with adjacent linear branching enhancement and infiltrative extension into fibroglandular tissue. | D | TCGA-AO-A0JM | condensed_caption:radiology_findings | [
"data/features/features_uni/TCGA-AO-A0JM-01Z-00-DX1.94E75EFD-E5F5-4DF8-93A0-ED94CB4D203A.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk3/pngs/TCGA-BRCA/TCGA-AO-A0JM/1.3.6.1.4.1.14519.5.2.1.9203.4002.454728436394916718626245859814/1.3.6.1.4.1.14519.5.2.1.9203.4002.114399706254337368650501059482",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_cpgpt_dnam/TCGA-BRCA/TCGA-AO-A0JM-01A__baddabcd-a902-4add-ba54-cc1b45e40ea2.pt | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-AO-A0JM__cd9fd232-1d69-4ef0-911d-28130243994f.pt | |||||
TCGA-AO-A0JM | TCGA-BRCA | 5,205,938,156,161,452,000 | 8,600,973,972,091,778,000 | train | mcq | from_caption | caption_pathology | pathology_findings | all_available | true | true | true | true | Which pathology finding best matches this case? | Irregular nests and cords in prominent desmoplastic stroma with brisk lymphoid-rich tumor-stroma interface inflammation. | Haphazard small angulated glands, tubules, and cords in dense collagenized desmoplasia with limited inflammation and adipose invasion. | Predominant trabecular and irregular nest architecture with geographic pallor, hemorrhagic stromal injury/necrosis, and patchy stromal lymphocytes. | Irregular angulated tubules with small nests and cords in dense desmoplastic stroma, plus conspicuous lymphoid aggregates. | Haphazard small angulated glands, tubules, and cords in dense collagenized desmoplasia with limited inflammation and adipose invasion. | B | TCGA-AO-A0JM | condensed_caption:pathology_findings | [
"data/features/features_uni/TCGA-AO-A0JM-01Z-00-DX1.94E75EFD-E5F5-4DF8-93A0-ED94CB4D203A.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk3/pngs/TCGA-BRCA/TCGA-AO-A0JM/1.3.6.1.4.1.14519.5.2.1.9203.4002.454728436394916718626245859814/1.3.6.1.4.1.14519.5.2.1.9203.4002.114399706254337368650501059482",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_cpgpt_dnam/TCGA-BRCA/TCGA-AO-A0JM-01A__baddabcd-a902-4add-ba54-cc1b45e40ea2.pt | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-AO-A0JM__cd9fd232-1d69-4ef0-911d-28130243994f.pt | |||||
TCGA-AO-A0JM | TCGA-BRCA | 6,858,132,529,743,024,000 | 8,327,158,739,603,489,000 | train | mcq | from_caption | caption_genomics | genomic_findings | all_available | true | true | true | true | Which genomic finding best matches this case? | TP53 truncation with biallelic-appearing PTEN loss; basal-like RNA labeling despite HER2/ERBB2-high, ESR1/PGR-low expression. | LumA, ESR1/FOXA1/GATA3-high, MKI67-low; mutation- and copy-number–silent; high BRCA1 and ESR1 promoter methylation; ER-high/PR-low/HER2-low. | LumB transcriptomic subtype with ESR1/FOXA1/GATA3 and ERBB2 RNA expression, genomically quiet, low TMB, ESR1/GSTP1 methylation. | Basal-like, ESR1/PGR-low, HER2-low transcriptome with MYC, interferon, and unfolded protein response enrichment; mutation/copy-number silent; TMB 0.03. | LumB transcriptomic subtype with ESR1/FOXA1/GATA3 and ERBB2 RNA expression, genomically quiet, low TMB, ESR1/GSTP1 methylation. | C | TCGA-AO-A0JM | condensed_caption:genomic_findings | [
"data/features/features_uni/TCGA-AO-A0JM-01Z-00-DX1.94E75EFD-E5F5-4DF8-93A0-ED94CB4D203A.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk3/pngs/TCGA-BRCA/TCGA-AO-A0JM/1.3.6.1.4.1.14519.5.2.1.9203.4002.454728436394916718626245859814/1.3.6.1.4.1.14519.5.2.1.9203.4002.114399706254337368650501059482",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_cpgpt_dnam/TCGA-BRCA/TCGA-AO-A0JM-01A__baddabcd-a902-4add-ba54-cc1b45e40ea2.pt | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-AO-A0JM__cd9fd232-1d69-4ef0-911d-28130243994f.pt | |||||
TCGA-AO-A0JM | TCGA-BRCA | 1,563,141,250,366,584,600 | 6,253,431,367,140,380,000 | train | mcq | from_caption | caption_integrated | integrated_interpretation | all_available | true | true | true | true | Which integrated interpretation best matches this case? | Infiltrative gland-forming carcinoma matched to irregular enhancing mass, with luminal B expression despite absent detectable driver alterations. | Lobular-pattern discohesive infiltrative carcinoma chiefly distinguished by luminal transcriptional support without morphology-defining driver alteration. | Desmoplastic invasive duct-forming carcinoma with necrotic foci and fat infiltration paired with RNA-level HER2-driven biology lacking DNA amplification. | Copy-number-quiet luminal invasive carcinoma combining strongly gland-forming desmoplastic morphology with PI3K-activated, HR-proficient, ER-high biology. | Infiltrative gland-forming carcinoma matched to irregular enhancing mass, with luminal B expression despite absent detectable driver alterations. | A | TCGA-AO-A0JM | condensed_caption:integrated_interpretation | [
"data/features/features_uni/TCGA-AO-A0JM-01Z-00-DX1.94E75EFD-E5F5-4DF8-93A0-ED94CB4D203A.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk3/pngs/TCGA-BRCA/TCGA-AO-A0JM/1.3.6.1.4.1.14519.5.2.1.9203.4002.454728436394916718626245859814/1.3.6.1.4.1.14519.5.2.1.9203.4002.114399706254337368650501059482",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_cpgpt_dnam/TCGA-BRCA/TCGA-AO-A0JM-01A__baddabcd-a902-4add-ba54-cc1b45e40ea2.pt | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-AO-A0JM__cd9fd232-1d69-4ef0-911d-28130243994f.pt | |||||
TCGA-AO-A12F | TCGA-BRCA | 9,063,184,297,170,379,000 | 6,575,269,353,482,634,000 | train | mcq | from_caption | caption_radiology | radiology_findings | all_available | true | true | true | true | Which radiology finding best matches this case? | Irregular non-mass to mass-like enhancement with clumped/streaky tissue and later faint linear-patchy enhancement. | Dominant irregular mass-like breast lesion with conspicuous heterogeneous enhancement and nearby smaller enhancing foci. | Large irregular heterogeneous enhancing mass occupying much of imaged breast parenchyma, with patchy brighter internal foci and partly indistinct lobulated margins. | Focal posterior breast mass at pectoralis/chest wall interface, irregular heterogeneous enhancement, mass-like rather than nonmass or diffuse. | Large irregular heterogeneous enhancing mass occupying much of imaged breast parenchyma, with patchy brighter internal foci and partly indistinct lobulated margins. | C | TCGA-AO-A12F | condensed_caption:radiology_findings | [
"data/features/features_uni/TCGA-AO-A12F-01Z-00-DX1.847C8E4F-3F37-4B1D-8E6E-ACD14391AD89.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk3/pngs/TCGA-BRCA/TCGA-AO-A12F/1.3.6.1.4.1.14519.5.2.1.9203.4002.240753407080370737439271619596/1.3.6.1.4.1.14519.5.2.1.9203.4002.113170262927555385612922478544",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_cpgpt_dnam/TCGA-BRCA/TCGA-AO-A12F-01A__bad2eefd-6cc3-4c6a-abd9-d51540a2ce9d.pt | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-AO-A12F__d6882616-b77d-4d4c-90dc-7318c57876e1.pt | |||||
TCGA-AO-A12F | TCGA-BRCA | 42,100,142,512,233,784 | 5,366,723,286,272,082,000 | train | mcq | from_caption | caption_pathology | pathology_findings | all_available | true | true | true | true | Which pathology finding best matches this case? | Compact trabecular-to-solid invasive carcinoma with limited luminal formation, monomorphic hyperchromatic cells, scant inflammation, and no conspicuous necrosis. | Lymphoid-rich fibrosing stroma with broad fibrous bands, chronic inflammation, whorled fascicular sclerosis, and only scattered entrapped gland-like epithelium. | Haphazard irregular glands, small tubules, and cords in fibrotic-desmoplastic stroma, extending near adipose tissue with patchy chronic inflammation. | Irregular nests and expansile nodular islands in desmoplastic stroma with large central acellular eosinophilic zones, comedo-like necrosis, and patchy inflammation. | Irregular nests and expansile nodular islands in desmoplastic stroma with large central acellular eosinophilic zones, comedo-like necrosis, and patchy inflammation. | D | TCGA-AO-A12F | condensed_caption:pathology_findings | [
"data/features/features_uni/TCGA-AO-A12F-01Z-00-DX1.847C8E4F-3F37-4B1D-8E6E-ACD14391AD89.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk3/pngs/TCGA-BRCA/TCGA-AO-A12F/1.3.6.1.4.1.14519.5.2.1.9203.4002.240753407080370737439271619596/1.3.6.1.4.1.14519.5.2.1.9203.4002.113170262927555385612922478544",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_cpgpt_dnam/TCGA-BRCA/TCGA-AO-A12F-01A__bad2eefd-6cc3-4c6a-abd9-d51540a2ce9d.pt | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-AO-A12F__d6882616-b77d-4d4c-90dc-7318c57876e1.pt | |||||
TCGA-AO-A12F | TCGA-BRCA | 7,417,669,452,316,885,000 | 3,652,568,074,087,856,000 | train | mcq | from_caption | caption_genomics | genomic_findings | all_available | true | true | true | true | Which genomic finding best matches this case? | GATA3 frameshift with otherwise driver-sparse, copy-number quiet genome; very low TMB; ESR1/PGR/FOXA1/GATA3 expression; LumA registry versus LumB RNA. | Truncating GATA3 frameshift with LumA subtype, strong ESR1/GATA3 expression, low PR, HER2-low, and no copy-number alterations. | TP53 missense plus MAP2K4 splice-site loss; LumA with high ESR1/FOXA1/GATA3, lower PR, HER2-low, copy-number quiet. | Basal registry subtype with separate HER2-enriched RNA signal; low ESR1/PGR, measurable ERBB2/GATA3, mutation-sparse copy-number-neutral low-TMB low-HRD profile. | Basal registry subtype with separate HER2-enriched RNA signal; low ESR1/PGR, measurable ERBB2/GATA3, mutation-sparse copy-number-neutral low-TMB low-HRD profile. | D | TCGA-AO-A12F | condensed_caption:genomic_findings | [
"data/features/features_uni/TCGA-AO-A12F-01Z-00-DX1.847C8E4F-3F37-4B1D-8E6E-ACD14391AD89.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk3/pngs/TCGA-BRCA/TCGA-AO-A12F/1.3.6.1.4.1.14519.5.2.1.9203.4002.240753407080370737439271619596/1.3.6.1.4.1.14519.5.2.1.9203.4002.113170262927555385612922478544",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_cpgpt_dnam/TCGA-BRCA/TCGA-AO-A12F-01A__bad2eefd-6cc3-4c6a-abd9-d51540a2ce9d.pt | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-AO-A12F__d6882616-b77d-4d4c-90dc-7318c57876e1.pt | |||||
TCGA-AO-A12F | TCGA-BRCA | 1,718,867,579,739,932,700 | 4,503,899,847,219,802,000 | train | mcq | from_caption | caption_integrated | integrated_interpretation | all_available | true | true | true | true | Which integrated interpretation best matches this case? | Hormone receptor-driven luminal A invasive tubule-forming carcinoma with PI3K-pathway dysregulation and fibroadipose invasion. | Immune-rich poorly differentiated non-luminal breast carcinoma, TP53-driven, lacking HRD and classic luminal pathway alterations. | Substantial necrotic solid-nested breast carcinoma with mixed basal/HER2-enriched transcriptional phenotype despite absence of canonical driver or genomic instability. | Lobular-pattern discohesive infiltrative carcinoma chiefly distinguished by luminal transcriptional support without morphology-defining driver alteration. | Substantial necrotic solid-nested breast carcinoma with mixed basal/HER2-enriched transcriptional phenotype despite absence of canonical driver or genomic instability. | C | TCGA-AO-A12F | condensed_caption:integrated_interpretation | [
"data/features/features_uni/TCGA-AO-A12F-01Z-00-DX1.847C8E4F-3F37-4B1D-8E6E-ACD14391AD89.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk3/pngs/TCGA-BRCA/TCGA-AO-A12F/1.3.6.1.4.1.14519.5.2.1.9203.4002.240753407080370737439271619596/1.3.6.1.4.1.14519.5.2.1.9203.4002.113170262927555385612922478544",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_cpgpt_dnam/TCGA-BRCA/TCGA-AO-A12F-01A__bad2eefd-6cc3-4c6a-abd9-d51540a2ce9d.pt | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-AO-A12F__d6882616-b77d-4d4c-90dc-7318c57876e1.pt | |||||
TCGA-AR-A24R | TCGA-BRCA | 3,309,521,828,127,305,000 | 84,217,550,187,795,060 | train | mcq | from_caption | caption_radiology | radiology_findings | all_available | true | true | true | true | Which radiology finding best matches this case? | Irregular hyperintense enhancing breast mass with internal heterogeneity and a conspicuous bright enhancing focus. | Small subtle enhancing focus in central retroareolar breast without confidently circumscribed mass contour. | Small irregular ill-defined lesion in lateral-to-upper breast ROI on sagittal MRI. | Irregular noncircumscribed breast parenchymal lesion with heterogeneous enhancement on MRI. | Small irregular ill-defined lesion in lateral-to-upper breast ROI on sagittal MRI. | C | TCGA-AR-A24R | condensed_caption:radiology_findings | [
"data/features/features_uni/TCGA-AR-A24R-01Z-00-DX1.47D79205-63E7-43E6-A513-2CD10DFA53C9.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk3/pngs/TCGA-BRCA/TCGA-AR-A24R/1.3.6.1.4.1.14519.5.2.1.3344.4002.497562410445823123071683209253/1.3.6.1.4.1.14519.5.2.1.3344.4002.102442138533365127368023843246",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_cpgpt_dnam/TCGA-BRCA/TCGA-AR-A24R-01A__93286a9c-b0b5-4068-824b-b6a4e35d8055.pt | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-AR-A24R__7e035247-3586-443f-a94c-0addbaf3b17f.pt | |||||
TCGA-AR-A24R | TCGA-BRCA | 364,705,288,443,210,800 | 4,123,103,339,279,527,000 | train | mcq | from_caption | caption_pathology | pathology_findings | all_available | true | true | true | true | Which pathology finding best matches this case? | Heterogeneous gland-forming carcinoma with irregular angulated glands, small tubules, fused nests, and focal cribriform-solid areas in dense desmoplasia. | Densely packed small-medium cells in nests, cords, trabeculae, vaguely whorled desmoplastic stroma with mild patchy inflammation. | Densely cellular syncytial-sheet carcinoma with scant stroma and brisk diffuse lymphoplasmacytic infiltrate; focal peripheral adipose involvement. | Irregular angulated glands with cribriform-fused nests in broad collagenized desmoplastic bands, forming patchy infiltrative islands. | Densely packed small-medium cells in nests, cords, trabeculae, vaguely whorled desmoplastic stroma with mild patchy inflammation. | B | TCGA-AR-A24R | condensed_caption:pathology_findings | [
"data/features/features_uni/TCGA-AR-A24R-01Z-00-DX1.47D79205-63E7-43E6-A513-2CD10DFA53C9.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk3/pngs/TCGA-BRCA/TCGA-AR-A24R/1.3.6.1.4.1.14519.5.2.1.3344.4002.497562410445823123071683209253/1.3.6.1.4.1.14519.5.2.1.3344.4002.102442138533365127368023843246",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_cpgpt_dnam/TCGA-BRCA/TCGA-AR-A24R-01A__93286a9c-b0b5-4068-824b-b6a4e35d8055.pt | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-AR-A24R__7e035247-3586-443f-a94c-0addbaf3b17f.pt | |||||
TCGA-AR-A24R | TCGA-BRCA | 5,277,748,112,508,464,000 | 7,556,386,687,366,729,000 | train | mcq | from_caption | caption_genomics | genomic_findings | all_available | true | true | true | true | Which genomic finding best matches this case? | RUNX1 frameshift-only driver landscape; LumB with ESR1/PGR/FOXA1/GATA3 expression, MKI67 elevated, copy-number quiet. | PIK3CA H1047R and truncating GATA3 frameshift; LumA with HER2-low signaling, low MKI67, copy-number quiet, low TMB/HRD. | Basal-like subtype with TP53 R175H and PTEN H123D; low ESR1/PGR, low HER2 concordance, proliferative and EMT programs. | No detected panel mutations or copy-number changes; high ESR1/FOXA1/GATA3 with lower PGR; LumA registry but LumB RNA call. | RUNX1 frameshift-only driver landscape; LumB with ESR1/PGR/FOXA1/GATA3 expression, MKI67 elevated, copy-number quiet. | A | TCGA-AR-A24R | condensed_caption:genomic_findings | [
"data/features/features_uni/TCGA-AR-A24R-01Z-00-DX1.47D79205-63E7-43E6-A513-2CD10DFA53C9.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk3/pngs/TCGA-BRCA/TCGA-AR-A24R/1.3.6.1.4.1.14519.5.2.1.3344.4002.497562410445823123071683209253/1.3.6.1.4.1.14519.5.2.1.3344.4002.102442138533365127368023843246",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_cpgpt_dnam/TCGA-BRCA/TCGA-AR-A24R-01A__93286a9c-b0b5-4068-824b-b6a4e35d8055.pt | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-AR-A24R__7e035247-3586-443f-a94c-0addbaf3b17f.pt | |||||
TCGA-AR-A24R | TCGA-BRCA | 1,609,558,499,194,469,600 | 8,465,051,102,766,762,000 | train | mcq | from_caption | caption_integrated | integrated_interpretation | all_available | true | true | true | true | Which integrated interpretation best matches this case? | Invasive desmoplastic carcinoma extending toward adipose tissue with luminal B biology and unusually low genomic complexity despite RUNX1 loss. | Gland-forming invasive carcinoma with strong luminal-lineage program and exceptionally quiet genome centered on GATA3 alteration. | Desmoplastic infiltrative ductal carcinoma with adipose extension, biologically defined by TP53 loss and luminal-suppressed HER2-associated transcriptional program. | Luminal invasive carcinoma with GATA3-altered lineage program and unusually quiet genome lacking copy-number events or structural rearrangements. | Invasive desmoplastic carcinoma extending toward adipose tissue with luminal B biology and unusually low genomic complexity despite RUNX1 loss. | A | TCGA-AR-A24R | condensed_caption:integrated_interpretation | [
"data/features/features_uni/TCGA-AR-A24R-01Z-00-DX1.47D79205-63E7-43E6-A513-2CD10DFA53C9.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk3/pngs/TCGA-BRCA/TCGA-AR-A24R/1.3.6.1.4.1.14519.5.2.1.3344.4002.497562410445823123071683209253/1.3.6.1.4.1.14519.5.2.1.3344.4002.102442138533365127368023843246",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_cpgpt_dnam/TCGA-BRCA/TCGA-AR-A24R-01A__93286a9c-b0b5-4068-824b-b6a4e35d8055.pt | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-AR-A24R__7e035247-3586-443f-a94c-0addbaf3b17f.pt | |||||
TCGA-BH-A0B1 | TCGA-BRCA | 7,363,081,139,597,454,000 | 8,916,494,896,702,569,000 | train | mcq | from_caption | caption_radiology | radiology_findings | all_available | true | true | false | true | Which radiology finding best matches this case? | Irregular focal parenchymal lesion with indistinct margins and a brighter peripheral focus within fibroglandular tissue. | Irregular heterogeneous enhancing mass spans substantial breast parenchyma, with adjacent chest wall/axillary-side and separate inferior boxed soft-tissue foci. | Irregular spiculated soft-tissue breast mass with radiating linear extensions and internal heterogeneity. | Irregular heterogeneously hyperintense mass with clustered nonuniform internal enhancement; possible adjacent separate parenchymal enhancing focus. | Irregular heterogeneously hyperintense mass with clustered nonuniform internal enhancement; possible adjacent separate parenchymal enhancing focus. | D | TCGA-BH-A0B1 | condensed_caption:radiology_findings | [
"data/features/features_uni/TCGA-BH-A0B1-01Z-00-DX1.CC60D284-04FB-4B73-90AA-FCE9185DADB6.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk4/pngs/TCGA-BRCA/TCGA-BH-A0B1/1.3.6.1.4.1.14519.5.2.1.6450.4002.241701955124018203091289893235/1.3.6.1.4.1.14519.5.2.1.6450.4002.126111704622944477264535522865",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-BH-A0B1__aabb4a65-aff2-4f78-a969-bacbe5b80856.pt | ||||||
TCGA-BH-A0B1 | TCGA-BRCA | 4,741,909,697,549,132,000 | 2,934,200,326,269,143,000 | train | mcq | from_caption | caption_pathology | pathology_findings | all_available | true | true | false | true | Which pathology finding best matches this case? | Angulated tubules, small nests, cords, and dispersed single-cell linear infiltration within desmoplastic stroma extending into fat. | Compact trabecular-to-solid invasive carcinoma with limited luminal formation, monomorphic hyperchromatic cells, scant inflammation, and no conspicuous necrosis. | Patchy low-cellularity infiltrative carcinoma with thin cords and small tubules in densely collagenized desmoplasia; mild chronic inflammation; no conspicuous necrosis. | Multinodular solid invasive nests infiltrate fibroadipose tissue, with focal cribriform punctate lumina and conspicuous adipose involvement. | Angulated tubules, small nests, cords, and dispersed single-cell linear infiltration within desmoplastic stroma extending into fat. | A | TCGA-BH-A0B1 | condensed_caption:pathology_findings | [
"data/features/features_uni/TCGA-BH-A0B1-01Z-00-DX1.CC60D284-04FB-4B73-90AA-FCE9185DADB6.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk4/pngs/TCGA-BRCA/TCGA-BH-A0B1/1.3.6.1.4.1.14519.5.2.1.6450.4002.241701955124018203091289893235/1.3.6.1.4.1.14519.5.2.1.6450.4002.126111704622944477264535522865",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-BH-A0B1__aabb4a65-aff2-4f78-a969-bacbe5b80856.pt | ||||||
TCGA-BH-A0B1 | TCGA-BRCA | 1,857,976,465,366,109,400 | 6,286,164,121,435,561,000 | train | mcq | from_caption | caption_genomics | genomic_findings | all_available | true | true | false | true | Which genomic finding best matches this case? | Luminal hormone-lineage profile with ER-high/PR-low/HER2-low surrogate, elevated aneuploidy, low HRD, and high ESR1 methylation. | GATA3 frameshift with copy-number-neutral, fusion-negative luminal profile; ESR1/PGR/FOXA1/GATA3 expression, LumA registry but LumB classifier. | Isolated TP53 p.R342P with copy-number-neutral genome, low TMB/HRD, and luminal ESR1/FOXA1/GATA3 expression despite LumA/LumB discordance. | Genomically quiet LumA tumor: no panel mutations or copy-number changes; high ESR1/PGR/FOXA1/GATA3; low TMB 1.08/Mb. | Genomically quiet LumA tumor: no panel mutations or copy-number changes; high ESR1/PGR/FOXA1/GATA3; low TMB 1.08/Mb. | D | TCGA-BH-A0B1 | condensed_caption:genomic_findings | [
"data/features/features_uni/TCGA-BH-A0B1-01Z-00-DX1.CC60D284-04FB-4B73-90AA-FCE9185DADB6.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk4/pngs/TCGA-BRCA/TCGA-BH-A0B1/1.3.6.1.4.1.14519.5.2.1.6450.4002.241701955124018203091289893235/1.3.6.1.4.1.14519.5.2.1.6450.4002.126111704622944477264535522865",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-BH-A0B1__aabb4a65-aff2-4f78-a969-bacbe5b80856.pt | ||||||
TCGA-BH-A0B1 | TCGA-BRCA | 5,736,213,790,894,879,000 | 9,052,373,947,077,840,000 | train | mcq | from_caption | caption_integrated | integrated_interpretation | all_available | true | true | false | true | Which integrated interpretation best matches this case? | Small sampled invasive luminal breast mass with mixed duct-forming and single-cell infiltrative histology, lacking recurrent genomic drivers. | Gland-forming invasive ductal-pattern carcinoma invading adipose tissue, paired with luminal B estrogen-lineage program and convergent PI3K/AKT activation. | Luminal A, ER-high invasive gland-forming carcinoma with immune-rich stroma, biologically simple genome, and isolated TP53-driven pathology-genomic concordance. | Concordant invasive duct-forming carcinoma with luminal hormone-lineage program; molecular profiling chiefly refines subtype beyond morphology. | Small sampled invasive luminal breast mass with mixed duct-forming and single-cell infiltrative histology, lacking recurrent genomic drivers. | A | TCGA-BH-A0B1 | condensed_caption:integrated_interpretation | [
"data/features/features_uni/TCGA-BH-A0B1-01Z-00-DX1.CC60D284-04FB-4B73-90AA-FCE9185DADB6.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk4/pngs/TCGA-BRCA/TCGA-BH-A0B1/1.3.6.1.4.1.14519.5.2.1.6450.4002.241701955124018203091289893235/1.3.6.1.4.1.14519.5.2.1.6450.4002.126111704622944477264535522865",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-BH-A0B1__aabb4a65-aff2-4f78-a969-bacbe5b80856.pt | ||||||
TCGA-BH-A0BG | TCGA-BRCA | 1,068,110,033,689,334,900 | 5,700,389,785,733,898,000 | train | mcq | from_caption | caption_radiology | radiology_findings | all_available | true | true | false | true | Which radiology finding best matches this case? | Irregular upper-central breast parenchymal lesion with heterogeneous patchy internal enhancement and infiltrative non-circumscribed architecture. | Irregular noncircumscribed enhancing focus with internal heterogeneity and variable conspicuity across slices, giving a suspicious infiltrative appearance. | Posterior-central breast MRI lesion is irregular stellate/spiculated, with radiating linear extensions and heterogeneous enhancement near chest wall interface. | Small focal enhancing breast mass with irregular non-circumscribed contours, appearing localized rather than multifocal or nodal-associated. | Small focal enhancing breast mass with irregular non-circumscribed contours, appearing localized rather than multifocal or nodal-associated. | D | TCGA-BH-A0BG | condensed_caption:radiology_findings | [
"data/features/features_uni/TCGA-BH-A0BG-01Z-00-DX1.0838FB7F-8C85-4687-9F70-D136A1063383.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk4/pngs/TCGA-BRCA/TCGA-BH-A0BG/1.3.6.1.4.1.14519.5.2.1.6450.4002.219496072079862696210057534066/1.3.6.1.4.1.14519.5.2.1.6450.4002.131555795150149358261388749093",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-BH-A0BG__742a677b-e99b-4916-bb92-3536c55ee5e3.pt | ||||||
TCGA-BH-A0BG | TCGA-BRCA | 8,510,204,039,885,144,000 | 1,765,337,579,130,401,300 | train | mcq | from_caption | caption_pathology | pathology_findings | all_available | true | true | false | true | Which pathology finding best matches this case? | Irregular angulated tubules, fused glands, and cribriform-to-nested structures in desmoplastic stroma with patchy chronic inflammation. | Angulated gland-forming nests and cords with variable tubular differentiation in abundant desmoplastic stroma; only mild scattered inflammation. | Heterogeneous infiltrative carcinoma with glands, nests, trabeculae, and cribriform areas in desmoplastic stroma, plus patchy lymphoid infiltrate. | Diffuse discohesive cords and strands infiltrate desmoplastic stroma and adipose tissue, with patchy chronic inflammation and absent gland formation. | Heterogeneous infiltrative carcinoma with glands, nests, trabeculae, and cribriform areas in desmoplastic stroma, plus patchy lymphoid infiltrate. | C | TCGA-BH-A0BG | condensed_caption:pathology_findings | [
"data/features/features_uni/TCGA-BH-A0BG-01Z-00-DX1.0838FB7F-8C85-4687-9F70-D136A1063383.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk4/pngs/TCGA-BRCA/TCGA-BH-A0BG/1.3.6.1.4.1.14519.5.2.1.6450.4002.219496072079862696210057534066/1.3.6.1.4.1.14519.5.2.1.6450.4002.131555795150149358261388749093",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-BH-A0BG__742a677b-e99b-4916-bb92-3536c55ee5e3.pt | ||||||
TCGA-BH-A0BG | TCGA-BRCA | 4,437,238,236,220,111,400 | 1,852,745,952,793,273,000 | train | mcq | from_caption | caption_genomics | genomic_findings | all_available | true | true | false | true | Which genomic finding best matches this case? | PIK3CA H1047R and TP53 H193R with LumA, high ESR1/PGR/FOXA1, HER2-low, copy-number quiet profile. | PIK3CA E545K with MAP2K4 missense; LumA, high ESR1/PGR, low HER2 signal, low TMB, HR-proficient, copy-number quiet. | Isolated CDH1 p.R63* truncation with LumB expression, preserved ESR1/PGR/FOXA1/GATA3, and entirely copy-number quiet low-TMB genome. | Basal-designated yet HER2-enriched mRNA profile, relative ERBB2 expression, aneuploidy, moderate chromosomal instability, HRD 19, interferon/cytolytic activity. | Basal-designated yet HER2-enriched mRNA profile, relative ERBB2 expression, aneuploidy, moderate chromosomal instability, HRD 19, interferon/cytolytic activity. | D | TCGA-BH-A0BG | condensed_caption:genomic_findings | [
"data/features/features_uni/TCGA-BH-A0BG-01Z-00-DX1.0838FB7F-8C85-4687-9F70-D136A1063383.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk4/pngs/TCGA-BRCA/TCGA-BH-A0BG/1.3.6.1.4.1.14519.5.2.1.6450.4002.219496072079862696210057534066/1.3.6.1.4.1.14519.5.2.1.6450.4002.131555795150149358261388749093",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-BH-A0BG__742a677b-e99b-4916-bb92-3536c55ee5e3.pt | ||||||
TCGA-BH-A0BG | TCGA-BRCA | 1,044,379,425,679,197,800 | 9,127,742,661,089,315,000 | train | mcq | from_caption | caption_integrated | integrated_interpretation | all_available | true | true | false | true | Which integrated interpretation best matches this case? | Lobular-pattern infiltrative morphology aligns with noncircumscribed subareolar lesion; genomics uniquely shows luminal, genomically quiet GATA3-altered biology. | Basal-like BRCA1/TP53/NF1-altered invasive breast carcinoma with DNA-repair and growth-factor pathway disruption, contrasting luminal comparator cases. | Ductal-pattern invasive carcinoma with hormone receptor-associated luminal B biology lacking defining driver, copy-number event, or HRD signature. | Early localized invasive carcinoma with glandular-solid heterogeneity and immune-activated basal-versus-HER2 transcriptional ambiguity despite absent defining drivers. | Early localized invasive carcinoma with glandular-solid heterogeneity and immune-activated basal-versus-HER2 transcriptional ambiguity despite absent defining drivers. | D | TCGA-BH-A0BG | condensed_caption:integrated_interpretation | [
"data/features/features_uni/TCGA-BH-A0BG-01Z-00-DX1.0838FB7F-8C85-4687-9F70-D136A1063383.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk4/pngs/TCGA-BRCA/TCGA-BH-A0BG/1.3.6.1.4.1.14519.5.2.1.6450.4002.219496072079862696210057534066/1.3.6.1.4.1.14519.5.2.1.6450.4002.131555795150149358261388749093",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-BH-A0BG__742a677b-e99b-4916-bb92-3536c55ee5e3.pt | ||||||
TCGA-BH-A0BQ | TCGA-BRCA | 2,666,933,266,489,506,000 | 6,568,213,487,476,884,000 | train | mcq | from_caption | caption_radiology | radiology_findings | all_available | true | true | true | true | Which radiology finding best matches this case? | Dominant rounded-to-irregular enhancing breast mass with internal heterogeneity and adjacent enhancing vascular structures on subtraction MRI. | Small irregular heterogeneously enhancing intraparenchymal breast mass with indistinct margins. | Small mildly heterogeneous enhancing nodular focus in medial posterior right breast parenchyma. | Irregular heterogeneously enhancing breast mass with noncircumscribed configuration and patchy internal signal variation. | Irregular heterogeneously enhancing breast mass with noncircumscribed configuration and patchy internal signal variation. | D | TCGA-BH-A0BQ | condensed_caption:radiology_findings | [
"data/features/features_uni/TCGA-BH-A0BQ-01Z-00-DX1.F5C6386B-BB2C-49DF-B3B8-6C4B80D060D4.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk4/pngs/TCGA-BRCA/TCGA-BH-A0BQ/1.3.6.1.4.1.14519.5.2.1.6450.4002.398551894345363033412310478053/1.3.6.1.4.1.14519.5.2.1.6450.4002.122499269301763646121908956218",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_cpgpt_dnam/TCGA-BRCA/TCGA-BH-A0BQ-01A__e881c84a-c04f-4463-8202-aad487ac0fac.pt | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-BH-A0BQ__68881256-49b8-4a19-87a9-afac4f1841d2.pt | |||||
TCGA-BH-A0BQ | TCGA-BRCA | 4,173,129,776,831,462,400 | 8,288,881,799,977,305,000 | train | mcq | from_caption | caption_pathology | pathology_findings | all_available | true | true | true | true | Which pathology finding best matches this case? | Abundant pale extracellular mucin with infiltrative angulated glands, cribriform-to-micropapillary clusters, desmoplasia, and patchy lymphoplasmacytic inflammation. | Predominantly papillary carcinoma with arborizing fibrovascular fronds, intraluminal papillae, cribriform-tubular fusion, and angulated invasive glands in desmoplastic stroma. | Uniform infiltrative angulated tubules and fused glands with focal cribriform-micropapillary luminal complexity in prominent desmoplastic stroma. | Invasive carcinoma with solid and cribriform foci and rounded gland containing central eosinophilic comedo-like debris. | Invasive carcinoma with solid and cribriform foci and rounded gland containing central eosinophilic comedo-like debris. | D | TCGA-BH-A0BQ | condensed_caption:pathology_findings | [
"data/features/features_uni/TCGA-BH-A0BQ-01Z-00-DX1.F5C6386B-BB2C-49DF-B3B8-6C4B80D060D4.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk4/pngs/TCGA-BRCA/TCGA-BH-A0BQ/1.3.6.1.4.1.14519.5.2.1.6450.4002.398551894345363033412310478053/1.3.6.1.4.1.14519.5.2.1.6450.4002.122499269301763646121908956218",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_cpgpt_dnam/TCGA-BRCA/TCGA-BH-A0BQ-01A__e881c84a-c04f-4463-8202-aad487ac0fac.pt | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-BH-A0BQ__68881256-49b8-4a19-87a9-afac4f1841d2.pt | |||||
TCGA-BH-A0BQ | TCGA-BRCA | 1,262,604,084,550,399,200 | 7,001,223,960,815,373,000 | train | mcq | from_caption | caption_genomics | genomic_findings | all_available | true | true | true | true | Which genomic finding best matches this case? | GATA3 truncating/splice alteration with PIK3CA H1047R; LumA ER-high/PR-low/HER2-low, low MKI67, copy-number silent. | LumA, ER-high/PR-low/HER2-low, strong ESR1/FOXA1/GATA3 with PGR, low MKI67, high ESR1 methylation, no fusions, modest aneuploidy. | TP53 p.R196* truncation with Basal-like RNA subtype, low ER/PR/HER2 surrogates, and exceptionally copy-number quiet genome. | PIK3CA p.E545K hotspot plus truncating GATA3 p.K357*, TP53/CDH1 wild type, luminal expression, copy-number quiet. | PIK3CA p.E545K hotspot plus truncating GATA3 p.K357*, TP53/CDH1 wild type, luminal expression, copy-number quiet. | D | TCGA-BH-A0BQ | condensed_caption:genomic_findings | [
"data/features/features_uni/TCGA-BH-A0BQ-01Z-00-DX1.F5C6386B-BB2C-49DF-B3B8-6C4B80D060D4.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk4/pngs/TCGA-BRCA/TCGA-BH-A0BQ/1.3.6.1.4.1.14519.5.2.1.6450.4002.398551894345363033412310478053/1.3.6.1.4.1.14519.5.2.1.6450.4002.122499269301763646121908956218",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_cpgpt_dnam/TCGA-BRCA/TCGA-BH-A0BQ-01A__e881c84a-c04f-4463-8202-aad487ac0fac.pt | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-BH-A0BQ__68881256-49b8-4a19-87a9-afac4f1841d2.pt | |||||
TCGA-BH-A0BQ | TCGA-BRCA | 7,811,296,172,608,341,000 | 8,757,050,545,935,519,000 | train | mcq | from_caption | caption_integrated | integrated_interpretation | all_available | true | true | true | true | Which integrated interpretation best matches this case? | Scirrhous adipose-invasive ductal carcinoma distinguished by luminal differentiation with isolated AKT1-driven PI3K/AKT signaling and genomically quiet biology. | Luminal-program, genomically quiet duct-forming carcinoma where invasive glandular-desmoplastic morphology aligns with GATA3-altered LumB biology. | Luminal-type infiltrative gland-forming carcinoma with distinctive comedo-like architectural heterogeneity and genomically quiet PIK3CA/GATA3-driven profile. | Desmoplastic invasive ductal-pattern carcinoma aligned with luminal A biology and exceptionally quiet genome, biologically refining stage IIA beyond morphology. | Luminal-type infiltrative gland-forming carcinoma with distinctive comedo-like architectural heterogeneity and genomically quiet PIK3CA/GATA3-driven profile. | C | TCGA-BH-A0BQ | condensed_caption:integrated_interpretation | [
"data/features/features_uni/TCGA-BH-A0BQ-01Z-00-DX1.F5C6386B-BB2C-49DF-B3B8-6C4B80D060D4.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk4/pngs/TCGA-BRCA/TCGA-BH-A0BQ/1.3.6.1.4.1.14519.5.2.1.6450.4002.398551894345363033412310478053/1.3.6.1.4.1.14519.5.2.1.6450.4002.122499269301763646121908956218",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_cpgpt_dnam/TCGA-BRCA/TCGA-BH-A0BQ-01A__e881c84a-c04f-4463-8202-aad487ac0fac.pt | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-BH-A0BQ__68881256-49b8-4a19-87a9-afac4f1841d2.pt | |||||
TCGA-BH-A0DH | TCGA-BRCA | 7,828,100,671,455,965,000 | 4,849,585,391,782,711,000 | train | mcq | from_caption | caption_radiology | radiology_findings | all_available | true | true | false | true | Which radiology finding best matches this case? | Broad central-to-lateral asymmetric heterogeneous enhancement, patchy-to-confluent across a large parenchymal area, with infiltrative non-circumscribed appearance. | Irregular non-circumscribed heterogeneous enhancing mass extends posteriorly toward the chest wall interface. | Broad heterogeneous enhancement with adjacent separate foci, suggesting multifocal or regionally distributed intraparenchymal disease. | Upper-central breast irregular heterogeneous enhancing mass with adjacent small enhancing foci or contiguous extension. | Broad heterogeneous enhancement with adjacent separate foci, suggesting multifocal or regionally distributed intraparenchymal disease. | C | TCGA-BH-A0DH | condensed_caption:radiology_findings | [
"data/features/features_uni/TCGA-BH-A0DH-01Z-00-DX1.968AA1FD-068C-4B90-8C95-85BF2EFC3E3F.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk4/pngs/TCGA-BRCA/TCGA-BH-A0DH/1.3.6.1.4.1.14519.5.2.1.6450.4002.319589426461630943566129258184/1.3.6.1.4.1.14519.5.2.1.6450.4002.132961897956430534507673116083",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-BH-A0DH__73aeda8d-ef07-4d3d-a0fc-643943dd046a.pt | ||||||
TCGA-BH-A0DH | TCGA-BRCA | 5,348,140,804,232,491,000 | 2,796,272,419,243,428,000 | train | mcq | from_caption | caption_pathology | pathology_findings | all_available | true | true | false | true | Which pathology finding best matches this case? | Conspicuous peritumoral lymphoid aggregates around duct-forming carcinoma in densely sclerotic desmoplastic stroma with soft-tissue invasion near adipose tissue. | Predominantly angulated glands and small tubules in prominent desmoplastic stroma, with small lymphoid aggregates but no brisk inflammation. | Irregular small nests, cords, and rounded aggregates with focal targetoid involvement around native structures in desmoplastic fibroadipose tissue. | Duct-forming invasive carcinoma with angulated glands, variable tubule formation, and patchy chronic inflammation in desmoplastic stroma. | Predominantly angulated glands and small tubules in prominent desmoplastic stroma, with small lymphoid aggregates but no brisk inflammation. | B | TCGA-BH-A0DH | condensed_caption:pathology_findings | [
"data/features/features_uni/TCGA-BH-A0DH-01Z-00-DX1.968AA1FD-068C-4B90-8C95-85BF2EFC3E3F.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk4/pngs/TCGA-BRCA/TCGA-BH-A0DH/1.3.6.1.4.1.14519.5.2.1.6450.4002.319589426461630943566129258184/1.3.6.1.4.1.14519.5.2.1.6450.4002.132961897956430534507673116083",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-BH-A0DH__73aeda8d-ef07-4d3d-a0fc-643943dd046a.pt | ||||||
TCGA-BH-A0DH | TCGA-BRCA | 8,162,855,248,092,384,000 | 988,803,863,436,786,600 | train | mcq | from_caption | caption_genomics | genomic_findings | all_available | true | true | false | true | Which genomic finding best matches this case? | PIK3CA p.H1047R hotspot with LumA profile, preserved ESR1/PGR, TP53/CDH1 wild-type, and no focal or arm-level copy-number changes. | Genomically quiet luminal-profile tumor: wild-type TP53/PIK3CA/GATA3, no copy-number events, low TMB, high ESR1 promoter methylation. | CDH1 p.Q23* with PIK3CA p.E542K; LumA, high ESR1/FOXA1/GATA3, TP53 wild-type, copy-number silent, very low TMB. | High aneuploidy, low HRD, high ESR1 promoter methylation, receptor-low ERBB2-high transcripts, discordant basal versus HER2-enriched calls. | Genomically quiet luminal-profile tumor: wild-type TP53/PIK3CA/GATA3, no copy-number events, low TMB, high ESR1 promoter methylation. | B | TCGA-BH-A0DH | condensed_caption:genomic_findings | [
"data/features/features_uni/TCGA-BH-A0DH-01Z-00-DX1.968AA1FD-068C-4B90-8C95-85BF2EFC3E3F.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk4/pngs/TCGA-BRCA/TCGA-BH-A0DH/1.3.6.1.4.1.14519.5.2.1.6450.4002.319589426461630943566129258184/1.3.6.1.4.1.14519.5.2.1.6450.4002.132961897956430534507673116083",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-BH-A0DH__73aeda8d-ef07-4d3d-a0fc-643943dd046a.pt | ||||||
TCGA-BH-A0DH | TCGA-BRCA | 5,323,740,259,179,042,000 | 7,351,537,114,805,336,000 | train | mcq | from_caption | caption_integrated | integrated_interpretation | all_available | true | true | false | true | Which integrated interpretation best matches this case? | Gland-forming desmoplastic invasive carcinoma paired with multifocal-appearing heterogeneous enhancement and exceptionally alteration-sparse luminal biology. | Invasive papillary-patterned luminal breast carcinoma combining desmoplastic-hemorrhagic stromal heterogeneity with strong luminal lineage transcriptional signaling and low proliferation. | Lymphoid-fibrosclerotic sampled breast lesion with minimal epithelium and low-complexity luminal molecular context, fitting noninvasive Tis biology. | Desmoplastic invasive gland-forming carcinoma with adipocyte entrapment plus dual PIK3CA-driven PI3K activation supports luminal-type invasive breast carcinoma. | Gland-forming desmoplastic invasive carcinoma paired with multifocal-appearing heterogeneous enhancement and exceptionally alteration-sparse luminal biology. | A | TCGA-BH-A0DH | condensed_caption:integrated_interpretation | [
"data/features/features_uni/TCGA-BH-A0DH-01Z-00-DX1.968AA1FD-068C-4B90-8C95-85BF2EFC3E3F.h5"
] | [
"data/features/features_radiology/radiology_features.h5::series=data/processes/radiology/chunk4/pngs/TCGA-BRCA/TCGA-BH-A0DH/1.3.6.1.4.1.14519.5.2.1.6450.4002.319589426461630943566129258184/1.3.6.1.4.1.14519.5.2.1.6450.4002.132961897956430534507673116083",
"data/features/features_radiology/radiology_features.h5::s... | data/features/features_bulkformer_rna/TCGA-BRCA/TCGA-BH-A0DH__73aeda8d-ef07-4d3d-a0fc-643943dd046a.pt |
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