id stringlengths 1 3 | document_id stringlengths 4 9 | passages list | entities list | events list | coreferences list | relations list |
|---|---|---|---|---|---|---|
0 | vizamyl | [
{
"id": "vizamyl_section_S1",
"type": "adverse reactions",
"text": [
" 6 ADVERSE REACTIONS\n\n EXCERPT: Most commonly reported adverse reactions were flushing (2%), headache (1%), increased blood pressure (2%), nausea (1%), and dizziness (1%).\n\n\n\n To report SUSPECTED ADVERSE REACTIONS,... | [
{
"id": "vizamyl_entity_M1",
"type": "AdverseReaction",
"text": [
"flushing"
],
"offsets": [
[
84,
92
]
],
"normalized": []
},
{
"id": "vizamyl_entity_M2",
"type": "AdverseReaction",
"text": [
"headache"
],
"offsets": [
... | [] | [] | [
{
"id": "vizamyl_relation_RL1",
"type": "Effect",
"arg1_id": "M7",
"arg2_id": "M6",
"normalized": []
},
{
"id": "vizamyl_relation_RL2",
"type": "Hypothetical",
"arg1_id": "M25",
"arg2_id": "M24",
"normalized": []
}
] |
1 | horizant | [
{
"id": "horizant_section_S1",
"type": "adverse reactions",
"text": [
" 6 ADVERSE REACTIONS\n\n The following adverse reactions are described in more detail in the Warnings and Precautions section of the label:\n\n\n\n * Somnolence/sedation and dizziness [see Warnings and Precautions ( 5.... | [
{
"id": "horizant_entity_M1",
"type": "AdverseReaction",
"text": [
"Somnolence"
],
"offsets": [
[
152,
162
]
],
"normalized": []
},
{
"id": "horizant_entity_M2",
"type": "AdverseReaction",
"text": [
"sedation"
],
"offsets": ... | [] | [] | [
{
"id": "horizant_relation_RL1",
"type": "Hypothetical",
"arg1_id": "M78",
"arg2_id": "M77",
"normalized": []
},
{
"id": "horizant_relation_RL2",
"type": "Hypothetical",
"arg1_id": "M82",
"arg2_id": "M81",
"normalized": []
},
{
"id": "horizant_relation_RL3",
"... |
2 | pristiq | [
{
"id": "pristiq_section_S1",
"type": "adverse reactions",
"text": [
" 6 ADVERSE REACTIONS\n\n The following adverse reactions are discussed in greater detail in other sections of the label.\n\n\n\n * Hypersensitivity [see Contraindications (4) ] \n * Suicidal Thoughts and Behaviors i... | [
{
"id": "pristiq_entity_M1",
"type": "AdverseReaction",
"text": [
"Hypersensitivity"
],
"offsets": [
[
132,
148
]
],
"normalized": []
},
{
"id": "pristiq_entity_M2",
"type": "AdverseReaction",
"text": [
"Suicidal Thoughts"
],
... | [] | [] | [
{
"id": "pristiq_relation_RL1",
"type": "Effect",
"arg1_id": "M105",
"arg2_id": "M109",
"normalized": []
},
{
"id": "pristiq_relation_RL2",
"type": "Negated",
"arg1_id": "M107",
"arg2_id": "M106",
"normalized": []
},
{
"id": "pristiq_relation_RL3",
"type": "Ne... |
3 | beleodaq | [
{
"id": "beleodaq_section_S1",
"type": "adverse reactions",
"text": [
" 6 ADVERSE REACTIONS\n\n The following serious adverse reactions are described in more detail in other sections of the prescribing information.\n\n\n\n * Hematologic Toxicity [see Warnings and Precautions ( 5.1 )] \... | [
{
"id": "beleodaq_entity_M1",
"type": "AdverseReaction",
"text": [
"Hematologic Toxicity"
],
"offsets": [
[
155,
175
]
],
"normalized": []
},
{
"id": "beleodaq_entity_M2",
"type": "AdverseReaction",
"text": [
"Infection"
],
... | [] | [] | [
{
"id": "beleodaq_relation_RL1",
"type": "Effect",
"arg1_id": "M50",
"arg2_id": "M49",
"normalized": []
},
{
"id": "beleodaq_relation_RL2",
"type": "Negated",
"arg1_id": "M56",
"arg2_id": "M55",
"normalized": []
},
{
"id": "beleodaq_relation_RL3",
"type": "Eff... |
4 | picato | [
{
"id": "picato_section_S1",
"type": "adverse reactions",
"text": [
" 6 ADVERSE REACTIONS \n\n \n\n\n\n The following serious adverse reactions are discussed in more detail in other sections of the labeling:\n\n\n\n \n\n\n\n * Ophthalmic Adverse Reaction [see Warnings and Precautio... | [
{
"id": "picato_entity_M1",
"type": "AdverseReaction",
"text": [
"Ophthalmic Adverse Reaction"
],
"offsets": [
[
160,
187
]
],
"normalized": []
},
{
"id": "picato_entity_M2",
"type": "AdverseReaction",
"text": [
"Hypersensitivity Re... | [] | [] | [
{
"id": "picato_relation_RL1",
"type": "Hypothetical",
"arg1_id": "M59",
"arg2_id": "M67",
"normalized": []
},
{
"id": "picato_relation_RL2",
"type": "Hypothetical",
"arg1_id": "M61",
"arg2_id": "M67",
"normalized": []
},
{
"id": "picato_relation_RL3",
"type":... |
5 | dysport | [{"id":"dysport_section_S1","type":"adverse reactions","text":[" 6 ADVERSE REACTIONS\n\n The fol(...TRUNCATED) | [{"id":"dysport_entity_M1","type":"AdverseReaction","text":["Distant Spread of Toxin Effect"],"offse(...TRUNCATED) | [] | [] | [{"id":"dysport_relation_RL1","type":"Effect","arg1_id":"M76","arg2_id":"M75","normalized":[]},{"id"(...TRUNCATED) |
6 | xtandi | [{"id":"xtandi_section_S1","type":"adverse reactions","text":[" 6 ADVERSE REACTIONS\n\n The foll(...TRUNCATED) | [{"id":"xtandi_entity_M1","type":"AdverseReaction","text":["Seizure"],"offsets":[[113,120]],"normali(...TRUNCATED) | [] | [] | [{"id":"xtandi_relation_RL1","type":"Effect","arg1_id":"M134","arg2_id":"M132","normalized":[]},{"id(...TRUNCATED) |
7 | stendra | [{"id":"stendra_section_S1","type":"adverse reactions","text":[" 6 ADVERSE REACTIONS\n\n EXCERPT(...TRUNCATED) | [{"id":"stendra_entity_M1","type":"AdverseReaction","text":["headache"],"offsets":[[106,114]],"norma(...TRUNCATED) | [] | [] | [{"id":"stendra_relation_RL1","type":"Hypothetical","arg1_id":"M81","arg2_id":"M85","normalized":[]}(...TRUNCATED) |
8 | potiga | [{"id":"potiga_section_S1","type":"adverse reactions","text":[" 6 ADVERSE REACTIONS\n\n The foll(...TRUNCATED) | [{"id":"potiga_entity_M1","type":"AdverseReaction","text":["Retinal abnormalities"],"offsets":[[153,(...TRUNCATED) | [] | [] | [{"id":"potiga_relation_RL1","type":"Hypothetical","arg1_id":"M3","arg2_id":"M2","normalized":[]},{"(...TRUNCATED) |
9 | dalvance | [{"id":"dalvance_section_S1","type":"adverse reactions","text":[" 6 ADVERSE REACTIONS\n\n Becaus(...TRUNCATED) | [{"id":"dalvance_entity_M1","type":"AdverseReaction","text":["nausea"],"offsets":[[375,381]],"normal(...TRUNCATED) | [] | [] | [{"id":"dalvance_relation_RL1","type":"Effect","arg1_id":"M42","arg2_id":"M43","normalized":[]},{"id(...TRUNCATED) |
End of preview. Expand
in Data Studio
Dataset Card for SPL ADR
The United States Food and Drug Administration (FDA) partnered with the National Library of Medicine to create a pilot dataset containing standardised information about known adverse reactions for 200 FDA-approved drugs. The Structured Product Labels (SPLs), the documents FDA uses to exchange information about drugs and other products, were manually annotated for adverse reactions at the mention level to facilitate development and evaluation of text mining tools for extraction of ADRs from all SPLs. The ADRs were then normalised to the Unified Medical Language System (UMLS) and to the Medical Dictionary for Regulatory Activities (MedDRA).
Citation Information
@article{demner2018dataset,
author = {Demner-Fushman, Dina and Shooshan, Sonya and Rodriguez, Laritza and Aronson,
Alan and Lang, Francois and Rogers, Willie and Roberts, Kirk and Tonning, Joseph},
title = {A dataset of 200 structured product labels annotated for adverse drug reactions},
journal = {Scientific Data},
volume = {5},
year = {2018},
month = {01},
pages = {180001},
url = {
https://www.researchgate.net/publication/322810855_A_dataset_of_200_structured_product_labels_annotated_for_adverse_drug_reactions
},
doi = {10.1038/sdata.2018.1}
}
- Downloads last month
- 29